Inhibition of autophagy by chloroquine induces apoptosis in primary effusion lymphoma in vitro and in vivo through induction of endoplasmic reticulum stress

Apoptosis

Volumn 21, Issue 10, 2016, Pages 1191-1201

  Masud Alam, Md ^a   Kariya, Ryusho ^a   Kawaguchi, Azusa ^a   Matsuda, Kouki ^a   Kudo, Eriko ^a   Okada, Seiji ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

Author keywords

Apoptosis; Autophagy; Chloroquine (CQ); Endoplasmic Reticulum (ER) stress; Mouse model; Primary Effusion Lymphoma (PEL)

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; CASPASE 3; CHLOROQUINE; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR 2ALPHA; P65 PROTEIN; PHOSPHORYLATED AKT PROTEIN; PHOSPHORYLATED AKT S473 PROTEIN; PHOSPHORYLATED AKT T308 PROTEIN; PHOSPHORYLATED P65 PROTEIN; PHOSPHORYLATED STAT3 PROTEIN; PROTEIN KINASE B; STAT3 PROTEIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT;

AGGRESOME; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASCITES; AUTOLYSOSOME; AUTOPHAGOSOME; AUTOPHAGY; CELL DEATH; CELL GROWTH; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; FEMALE; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE SUBPOPULATION; MOUSE; MTT ASSAY; NONHUMAN; PRIMARY EFFUSION LYMPHOMA; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN PHOSPHORYLATION; SPLEEN WEIGHT; TUMOR CELL INOCULATION; UPREGULATION; WESTERN BLOTTING; ANIMAL; DRUG EFFECTS; ENDOPLASMIC RETICULUM; NUDE MOUSE; PATHOPHYSIOLOGY; PHYSIOLOGY; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; AUTOPHAGY; CELL LINE, TUMOR; CELL PROLIFERATION; CHLOROQUINE; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; FEMALE; HUMANS; LYMPHOMA, PRIMARY EFFUSION; MICE; MICE, NUDE;

EID: 84982822236     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-016-1277-7     Document Type: Article

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