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Volumn 16, Issue 1, 2016, Pages

Platelet inhibitory effects of juices from Pachyrhizus erosus L. root and Psidium guajava L. fruit: A randomized controlled trial in healthy volunteers

Author keywords

Antiplatelet effect; Blood pressure lowering effect; Guava fruit juice; Plasma cGMP; Systemic nitrate; Systemic nitrite; Yam bean root juice

Indexed keywords

ADENOSINE DIPHOSPHATE; ANTITHROMBOCYTIC AGENT; COLLAGEN; CYCLIC GMP; GUAVA EXTRACT; NITRATE; NITRITE; PACHYRHIZUS EROSUS EXTRACT; PLANT EXTRACT; POTASSIUM; UNCLASSIFIED DRUG; WATER;

EID: 84982702317     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/s12906-016-1255-1     Document Type: Article
Times cited : (26)

References (56)
  • 1
    • 13844269298 scopus 로고    scopus 로고
    • The role of nitric oxide in cardiovascular diseases
    • Naseem KM. The role of nitric oxide in cardiovascular diseases. Mol Aspects Med. 2005;26:33-65.
    • (2005) Mol Aspects Med , vol.26 , pp. 33-65
    • Naseem, K.M.1
  • 2
    • 33746245192 scopus 로고    scopus 로고
    • Insights into human hypertension: the role of endothelial dysfunction
    • Giansante C, Fiotti N. Insights into human hypertension: the role of endothelial dysfunction. J Hum Hypertens. 2006;20(10):725-6.
    • (2006) J Hum Hypertens , vol.20 , Issue.10 , pp. 725-726
    • Giansante, C.1    Fiotti, N.2
  • 3
    • 58849099597 scopus 로고    scopus 로고
    • Diminished NO generation by injured endothelium and loss of macula densa nNOS may contribute to sustained acute kidney injury after ischemia-reperfusion
    • Kwon O, Hong SM, Ramesh G. Diminished NO generation by injured endothelium and loss of macula densa nNOS may contribute to sustained acute kidney injury after ischemia-reperfusion. Am J Physiol Renal Physiol. 2009;296(1):F25-33.
    • (2009) Am J Physiol Renal Physiol , vol.296 , Issue.1 , pp. F25-F33
    • Kwon, O.1    Hong, S.M.2    Ramesh, G.3
  • 4
    • 33749236623 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase deficiency produces accelerated nephropathy in diabetic mice
    • Zhao HJ, Wang S, Cheng H, Zhang MZ, Takahashi T, Fogo AB, et al. Endothelial nitric oxide synthase deficiency produces accelerated nephropathy in diabetic mice. J Am Soc Nephrol. 2006;17(10):2664-9.
    • (2006) J Am Soc Nephrol , vol.17 , Issue.10 , pp. 2664-2669
    • Zhao, H.J.1    Wang, S.2    Cheng, H.3    Zhang, M.Z.4    Takahashi, T.5    Fogo, A.B.6
  • 5
    • 0027242030 scopus 로고
    • Hypercholesterolemia increases endothelial superoxide anion production
    • Ohara Y, Peterson TE, Harrison DG. Hypercholesterolemia increases endothelial superoxide anion production. J Clin Invest. 1993;91(6):2546-51.
    • (1993) J Clin Invest , vol.91 , Issue.6 , pp. 2546-2551
    • Ohara, Y.1    Peterson, T.E.2    Harrison, D.G.3
  • 6
    • 0028969847 scopus 로고
    • Nitric oxide activity in the human coronary circulation. Impact of risk factors for coronary atherosclerosis
    • Quyyumi AA, Dakak N, Andrews NP, Husain S, Arora S, Gilligan DM, et al. Nitric oxide activity in the human coronary circulation. Impact of risk factors for coronary atherosclerosis. J Clin Invest. 1995;95(4):1747-55.
    • (1995) J Clin Invest , vol.95 , Issue.4 , pp. 1747-1755
    • Quyyumi, A.A.1    Dakak, N.2    Andrews, N.P.3    Husain, S.4    Arora, S.5    Gilligan, D.M.6
  • 7
    • 79955375799 scopus 로고    scopus 로고
    • All-natural nitrite and nitrate containing dietary supplement promotes nitric oxide production and reduces triglycerides in humans
    • Zand J, Lanza F, Garg HK, Bryan NS. All-natural nitrite and nitrate containing dietary supplement promotes nitric oxide production and reduces triglycerides in humans. Nutr Res. 2011;31(4):262-9.
    • (2011) Nutr Res , vol.31 , Issue.4 , pp. 262-269
    • Zand, J.1    Lanza, F.2    Garg, H.K.3    Bryan, N.S.4
  • 8
    • 26944451356 scopus 로고    scopus 로고
    • Dietary arginine supplementation attenuates renal damage after relief of unilateral ureteral obstruction in rats
    • Ito K, Chen J, Seshan SV, Khodadadian JJ, Gallagher R, El Chaar M, et al. Dietary arginine supplementation attenuates renal damage after relief of unilateral ureteral obstruction in rats. Kidney Int. 2005;68(2):515-28.
    • (2005) Kidney Int , vol.68 , Issue.2 , pp. 515-528
    • Ito, K.1    Chen, J.2    Seshan, S.V.3    Khodadadian, J.J.4    Gallagher, R.5    Chaar, M.6
  • 9
    • 8244264753 scopus 로고    scopus 로고
    • A clinical trial of the effects of dietary patterns on blood pressure. DASH Collaborative Research Group
    • Appel LJ, Moore TJ, Obarzanek E, Vollmer WM, Svetkey LP, Sacks FM, et al. A clinical trial of the effects of dietary patterns on blood pressure. DASH Collaborative Research Group. N Engl J Med. 1997;336(16):1117-24.
    • (1997) N Engl J Med , vol.336 , Issue.16 , pp. 1117-1124
    • Appel, L.J.1    Moore, T.J.2    Obarzanek, E.3    Vollmer, W.M.4    Svetkey, L.P.5    Sacks, F.M.6
  • 11
    • 75149158338 scopus 로고    scopus 로고
    • Dietary nitrate in Japanese traditional foods lowers diastolic blood pressure in healthy volunteers
    • Sobko T, Marcus C, Govoni M, Kamiya S. Dietary nitrate in Japanese traditional foods lowers diastolic blood pressure in healthy volunteers. Nitric Oxide. 2010;22(2):136-40.
    • (2010) Nitric Oxide , vol.22 , Issue.2 , pp. 136-140
    • Sobko, T.1    Marcus, C.2    Govoni, M.3    Kamiya, S.4
  • 12
    • 84873470565 scopus 로고    scopus 로고
    • Vascular effects of dietary nitrate (as found in green leafy vegetables and beetroot) via the nitrate-nitrite-nitric oxide pathway
    • Lidder S, Webb AJ. Vascular effects of dietary nitrate (as found in green leafy vegetables and beetroot) via the nitrate-nitrite-nitric oxide pathway. Br J Clin Pharmacol. 2013;75(3):677-96.
    • (2013) Br J Clin Pharmacol , vol.75 , Issue.3 , pp. 677-696
    • Lidder, S.1    Webb, A.J.2
  • 13
    • 77955476126 scopus 로고    scopus 로고
    • Inorganic nitrate supplementation lowers blood pressure in humans: role for nitrite-derived NO
    • Kapil V, Milsom AB, Okorie M, Maleki-Toyserkani S, Akram F, Rehman F, et al. Inorganic nitrate supplementation lowers blood pressure in humans: role for nitrite-derived NO. Hypertension. 2010;56(2):274-81.
    • (2010) Hypertension , vol.56 , Issue.2 , pp. 274-281
    • Kapil, V.1    Milsom, A.B.2    Okorie, M.3    Maleki-Toyserkani, S.4    Akram, F.5    Rehman, F.6
  • 14
    • 39749182795 scopus 로고    scopus 로고
    • Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite
    • Webb AJ, Patel N, Loukogeorgakis S, Okorie M, Aboud Z, Misra S, et al. Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite. Hypertension. 2008;51(3):784-90.
    • (2008) Hypertension , vol.51 , Issue.3 , pp. 784-790
    • Webb, A.J.1    Patel, N.2    Loukogeorgakis, S.3    Okorie, M.4    Aboud, Z.5    Misra, S.6
  • 15
    • 0035849516 scopus 로고    scopus 로고
    • Select flavonoids and whole juice from purple grapes inhibit platelet function and enhance nitric oxide release
    • Freedman JE, Parker 3rd C, Li L, Perlman JA, Frei B, Ivanov V, et al. Select flavonoids and whole juice from purple grapes inhibit platelet function and enhance nitric oxide release. Circulation. 2001;103(23):2792-8.
    • (2001) Circulation , vol.103 , Issue.23 , pp. 2792-2798
    • Freedman, J.E.1    Parker, C.2    Li, L.3    Perlman, J.A.4    Frei, B.5    Ivanov, V.6
  • 16
    • 67649515752 scopus 로고    scopus 로고
    • Effects of pomegranate juice and extract polyphenols on platelet function
    • Mattiello T, Trifiro E, Jotti GS, Pulcinelli FM. Effects of pomegranate juice and extract polyphenols on platelet function. J Med Food. 2009;12(2):334-9.
    • (2009) J Med Food , vol.12 , Issue.2 , pp. 334-339
    • Mattiello, T.1    Trifiro, E.2    Jotti, G.S.3    Pulcinelli, F.M.4
  • 17
    • 68149153088 scopus 로고    scopus 로고
    • Effects of chronic and acute consumption of fruit- and vegetable-puree-based drinks on vasodilation, risk factors for CVD and the response as a result of the eNOS G298T polymorphism
    • George TW, Niwat C, Waroonphan S, Gordon MH, Lovegrove JA. Effects of chronic and acute consumption of fruit- and vegetable-puree-based drinks on vasodilation, risk factors for CVD and the response as a result of the eNOS G298T polymorphism. Proc Nutr Soc. 2009;68(2):148-61.
    • (2009) Proc Nutr Soc , vol.68 , Issue.2 , pp. 148-161
    • George, T.W.1    Niwat, C.2    Waroonphan, S.3    Gordon, M.H.4    Lovegrove, J.A.5
  • 18
    • 34547674896 scopus 로고    scopus 로고
    • Resveratrol inhibits rat aortic vascular smooth muscle cell proliferation via estrogen receptor dependent nitric oxide production
    • Ekshyyan VP, Hebert VY, Khandelwal A, Dugas TR. Resveratrol inhibits rat aortic vascular smooth muscle cell proliferation via estrogen receptor dependent nitric oxide production. J Cardiovasc Pharmacol. 2007;50(1):83-93.
    • (2007) J Cardiovasc Pharmacol , vol.50 , Issue.1 , pp. 83-93
    • Ekshyyan, V.P.1    Hebert, V.Y.2    Khandelwal, A.3    Dugas, T.R.4
  • 19
    • 20144388620 scopus 로고    scopus 로고
    • Beneficial effects of pomegranate juice on oxidation-sensitive genes and endothelial nitric oxide synthase activity at sites of perturbed shear stress
    • de Nigris F, Williams-Ignarro S, Lerman LO, Crimi E, Botti C, Mansueto G, et al. Beneficial effects of pomegranate juice on oxidation-sensitive genes and endothelial nitric oxide synthase activity at sites of perturbed shear stress. Proc Natl Acad Sci U S A. 2005;102(13):4896-901.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , Issue.13 , pp. 4896-4901
    • Nigris, F.1    Williams-Ignarro, S.2    Lerman, L.O.3    Crimi, E.4    Botti, C.5    Mansueto, G.6
  • 20
    • 78651304738 scopus 로고    scopus 로고
    • Hesperidin contributes to the vascular protective effects of orange juice: a randomized crossover study in healthy volunteers
    • Morand C, Dubray C, Milenkovic D, Lioger D, Martin JF, Scalbert A, et al. Hesperidin contributes to the vascular protective effects of orange juice: a randomized crossover study in healthy volunteers. Am J Clin Nutr. 2011;93(1):73-80.
    • (2011) Am J Clin Nutr , vol.93 , Issue.1 , pp. 73-80
    • Morand, C.1    Dubray, C.2    Milenkovic, D.3    Lioger, D.4    Martin, J.F.5    Scalbert, A.6
  • 21
    • 84982741016 scopus 로고    scopus 로고
    • Nutrigenomic effects of hesperidin, the major polyphenol of orange, related to its cardiovascular protective effects
    • Morand C, Milenkovic D, Chanet A, Deval C, Mazur A. Nutrigenomic effects of hesperidin, the major polyphenol of orange, related to its cardiovascular protective effects. FASEB J. 2011;25:582-9.
    • (2011) FASEB J , vol.25 , pp. 582-589
    • Morand, C.1    Milenkovic, D.2    Chanet, A.3    Deval, C.4    Mazur, A.5
  • 22
    • 25844519695 scopus 로고    scopus 로고
    • Antihypertensive effect of sweetie fruit in patients with stage I hypertension
    • Reshef N, Hayari Y, Goren C, Boaz M, Madar Z, Knobler H. Antihypertensive effect of sweetie fruit in patients with stage I hypertension. Am J Hypertens. 2005;18(10):1360-3.
    • (2005) Am J Hypertens , vol.18 , Issue.10 , pp. 1360-1363
    • Reshef, N.1    Hayari, Y.2    Goren, C.3    Boaz, M.4    Madar, Z.5    Knobler, H.6
  • 23
    • 34248366081 scopus 로고    scopus 로고
    • Phytochemical Screening and Antibacterial Properties of Organic Solvent Fractions of Psidium guajava Aqueous Leaf Extracts
    • Geidam Y, Ambali A, Onyeyili P. Phytochemical Screening and Antibacterial Properties of Organic Solvent Fractions of Psidium guajava Aqueous Leaf Extracts. Int J Pharmacol. 2007;3:68-73.
    • (2007) Int J Pharmacol , vol.3 , pp. 68-73
    • Geidam, Y.1    Ambali, A.2    Onyeyili, P.3
  • 24
    • 0035188653 scopus 로고    scopus 로고
    • Guava fruit (Psidium guajava L.) as a new source of antioxidant dietary fiber
    • Jiménez-Escrig A, Rincón M, Pulido R, Saura-Calixto F. Guava fruit (Psidium guajava L.) as a new source of antioxidant dietary fiber. J Agric Food Chem. 2001;49(11):5489-93.
    • (2001) J Agric Food Chem , vol.49 , Issue.11 , pp. 5489-5493
    • Jiménez-Escrig, A.1    Rincón, M.2    Pulido, R.3    Saura-Calixto, F.4
  • 25
    • 77951704683 scopus 로고    scopus 로고
    • Anti-hypertensive effect of pink guava Psidium guajava puree on spontaneous hypertensive rats
    • Ayub M, Norazmir M, Mamot S, Jeeven K, Hadijah H. Anti-hypertensive effect of pink guava Psidium guajava puree on spontaneous hypertensive rats. Inter Food Res J. 2010;17:89-96.
    • (2010) Inter Food Res J , vol.17 , pp. 89-96
    • Ayub, M.1    Norazmir, M.2    Mamot, S.3    Jeeven, K.4    Hadijah, H.5
  • 26
    • 12244259695 scopus 로고    scopus 로고
    • Cardioprotective effects of extracts from Psidium guajava L and Limonium wrightii, Okinawan medicinal plants, against ischemia-reperfusion injury in perfused rat hearts
    • Yamashiro S, Noguchi K, Matsuzaki T, Miyagi K, Nakasone J, Sakanashi M, et al. Cardioprotective effects of extracts from Psidium guajava L and Limonium wrightii, Okinawan medicinal plants, against ischemia-reperfusion injury in perfused rat hearts. Pharmacology. 2003;67(3):128-35.
    • (2003) Pharmacology , vol.67 , Issue.3 , pp. 128-135
    • Yamashiro, S.1    Noguchi, K.2    Matsuzaki, T.3    Miyagi, K.4    Nakasone, J.5    Sakanashi, M.6
  • 27
    • 76149118464 scopus 로고    scopus 로고
    • Exract from leaf of Psidium guajava L. depresses the guinea pig atrial contractility by interfering with potassium and calcium channels
    • Gondim A, de Oliveira V, dos Santos S, da Silva B, de Vasconcelos C, Conde-Garcia E. Exract from leaf of Psidium guajava L. depresses the guinea pig atrial contractility by interfering with potassium and calcium channels. Braz J Pharm Sci. 2010;43(5):483-9.
    • (2010) Braz J Pharm Sci , vol.43 , Issue.5 , pp. 483-489
    • Gondim, A.1    Oliveira, V.2    Santos, S.3    Silva, B.4    Vasconcelos, C.5    Conde-Garcia, E.6
  • 28
    • 84893664394 scopus 로고    scopus 로고
    • Immunomodulatory activity of Bengkoang (Pachyrhizus erosus) fiber extract in vitro and in vivo
    • Kumalasari ID, Nishi K, Harmayani E, Raharjo S, Sugahara T. Immunomodulatory activity of Bengkoang (Pachyrhizus erosus) fiber extract in vitro and in vivo. Cytotechnology. 2014;66(1):75-85.
    • (2014) Cytotechnology , vol.66 , Issue.1 , pp. 75-85
    • Kumalasari, I.D.1    Nishi, K.2    Harmayani, E.3    Raharjo, S.4    Sugahara, T.5
  • 29
    • 0037251861 scopus 로고    scopus 로고
    • Methodologies for the sensitive and specific measurement of S-nitrosothiols, iron-nitrosyls, and nitrite in biological samples
    • Yang BK, Vivas EX, Reiter CD, Gladwin MT. Methodologies for the sensitive and specific measurement of S-nitrosothiols, iron-nitrosyls, and nitrite in biological samples. Free Radic Res. 2003;37(1):1-10.
    • (2003) Free Radic Res , vol.37 , Issue.1 , pp. 1-10
    • Yang, B.K.1    Vivas, E.X.2    Reiter, C.D.3    Gladwin, M.T.4
  • 31
    • 44849097211 scopus 로고    scopus 로고
    • Chemiluminescent detection of S-nitrosated proteins: comparison of tri-iodide, copper/CO/cysteine, and modified copper/cysteine methods
    • Basu S, Wang X, Gladwin MT, Kim-Shapiro DB. Chemiluminescent detection of S-nitrosated proteins: comparison of tri-iodide, copper/CO/cysteine, and modified copper/cysteine methods. Methods Enzymol. 2008;440:137-56.
    • (2008) Methods Enzymol , vol.440 , pp. 137-156
    • Basu, S.1    Wang, X.2    Gladwin, M.T.3    Kim-Shapiro, D.B.4
  • 32
    • 78651139188 scopus 로고
    • The aggregation of blood platelets
    • Born GVR, Cross MJ. The aggregation of blood platelets. J Physiol. 1963;168:178-95.
    • (1963) J Physiol , vol.168 , pp. 178-195
    • Born, G.V.R.1    Cross, M.J.2
  • 33
    • 9144239404 scopus 로고    scopus 로고
    • Platelet aggregation: turbidimetric measurements
    • Jarvis GE. Platelet aggregation: turbidimetric measurements. Methods Mol Biol. 2004;272:65-76.
    • (2004) Methods Mol Biol , vol.272 , pp. 65-76
    • Jarvis, G.E.1
  • 35
    • 0030601646 scopus 로고    scopus 로고
    • Determination of nitrite in human blood by combination of a specific sample preparation with high-performance anion-exchange chromatography and electrochemical detection
    • Preik-Steinhoff H, Kelm M. Determination of nitrite in human blood by combination of a specific sample preparation with high-performance anion-exchange chromatography and electrochemical detection. J Chromatogr B Biomed Appl. 1996;685(2):348-52.
    • (1996) J Chromatogr B Biomed Appl , vol.685 , Issue.2 , pp. 348-352
    • Preik-Steinhoff, H.1    Kelm, M.2
  • 36
    • 0028932526 scopus 로고
    • The effect of amoxycillin on salivary nitrite concentrations: an important mechanism of adverse reactions?
    • Dougall HT, Smith L, Duncan C, Benjamin N. The effect of amoxycillin on salivary nitrite concentrations: an important mechanism of adverse reactions? Br J Clin Pharmacol. 1995;39(4):460-2.
    • (1995) Br J Clin Pharmacol , vol.39 , Issue.4 , pp. 460-462
    • Dougall, H.T.1    Smith, L.2    Duncan, C.3    Benjamin, N.4
  • 37
    • 0029075644 scopus 로고
    • Chemical generation of nitric oxide in the mouth from the enterosalivary circulation of dietary nitrate
    • Duncan C, Dougall H, Johnston P, Green S, Brogan R, Leifert C, et al. Chemical generation of nitric oxide in the mouth from the enterosalivary circulation of dietary nitrate. Nat Med. 1995;1(6):546-51.
    • (1995) Nat Med , vol.1 , Issue.6 , pp. 546-551
    • Duncan, C.1    Dougall, H.2    Johnston, P.3    Green, S.4    Brogan, R.5    Leifert, C.6
  • 38
    • 55549095980 scopus 로고    scopus 로고
    • The increase in plasma nitrite after a dietary nitrate load is markedly attenuated by an antibacterial mouthwash
    • Govoni M, Jansson EA, Weitzberg E, Lundberg JO. The increase in plasma nitrite after a dietary nitrate load is markedly attenuated by an antibacterial mouthwash. Nitric Oxide. 2008;19(4):333-7.
    • (2008) Nitric Oxide , vol.19 , Issue.4 , pp. 333-337
    • Govoni, M.1    Jansson, E.A.2    Weitzberg, E.3    Lundberg, J.O.4
  • 39
    • 45549098720 scopus 로고    scopus 로고
    • A mammalian functional nitrate reductase that regulates nitrite and nitric oxide homeostasis
    • Jansson EA, Huang L, Malkey R, Govoni M, Nihlen C, Olsson A, et al. A mammalian functional nitrate reductase that regulates nitrite and nitric oxide homeostasis. Nat Chem Biol. 2008;4(7):411-7.
    • (2008) Nat Chem Biol , vol.4 , Issue.7 , pp. 411-417
    • Jansson, E.A.1    Huang, L.2    Malkey, R.3    Govoni, M.4    Nihlen, C.5    Olsson, A.6
  • 40
    • 0036036981 scopus 로고    scopus 로고
    • The ingestion of inorganic nitrate increases gastric S-nitrosothiol levels and inhibits platelet function in humans
    • Richardson G, Hicks SL, O'Byrne S, Frost MT, Moore K, Benjamin N, et al. The ingestion of inorganic nitrate increases gastric S-nitrosothiol levels and inhibits platelet function in humans. Nitric Oxide. 2002;7(1):24-9.
    • (2002) Nitric Oxide , vol.7 , Issue.1 , pp. 24-29
    • Richardson, G.1    Hicks, S.L.2    O'Byrne, S.3    Frost, M.T.4    Moore, K.5    Benjamin, N.6
  • 41
    • 0025020416 scopus 로고
    • Cardioprotective effects of acidified sodium nitrite in myocardial ischemia with reperfusion
    • Johnson 3rd G, Tsao PS, Mulloy D, Lefer AM. Cardioprotective effects of acidified sodium nitrite in myocardial ischemia with reperfusion. J Pharmacol Exp Ther. 1990;252(1):35-41.
    • (1990) J Pharmacol Exp Ther , vol.252 , Issue.1 , pp. 35-41
    • Johnson, G.1    Tsao, P.S.2    Mulloy, D.3    Lefer, A.M.4
  • 43
    • 10744220361 scopus 로고    scopus 로고
    • Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation
    • Cosby K, Partovi KS, Crawford JH, Patel RP, Reiter CD, Martyr S, et al. Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation. Nat Med. 2003;9(12):1498-505.
    • (2003) Nat Med , vol.9 , Issue.12 , pp. 1498-1505
    • Cosby, K.1    Partovi, K.S.2    Crawford, J.H.3    Patel, R.P.4    Reiter, C.D.5    Martyr, S.6
  • 44
    • 84890568414 scopus 로고    scopus 로고
    • Antiplatelet effects of dietary nitrate in healthy volunteers: involvement of cGMP and influence of sex
    • Velmurugan S, Kapil V, Ghosh SM, Davies S, McKnight A, Aboud Z, et al. Antiplatelet effects of dietary nitrate in healthy volunteers: involvement of cGMP and influence of sex. Free Radic Biol Med. 2013;65:1521-32.
    • (2013) Free Radic Biol Med , vol.65 , pp. 1521-1532
    • Velmurugan, S.1    Kapil, V.2    Ghosh, S.M.3    Davies, S.4    McKnight, A.5    Aboud, Z.6
  • 45
    • 0028027071 scopus 로고
    • Plasma arteriovenous cGMP difference as a useful indicator of nitrate tolerance in patients with heart failure
    • Tsutamoto T, Kinoshita M, Ohbayashi Y, Wada A, Maeda Y, Adachi T. Plasma arteriovenous cGMP difference as a useful indicator of nitrate tolerance in patients with heart failure. Circulation. 1994;90(2):823-9.
    • (1994) Circulation , vol.90 , Issue.2 , pp. 823-829
    • Tsutamoto, T.1    Kinoshita, M.2    Ohbayashi, Y.3    Wada, A.4    Maeda, Y.5    Adachi, T.6
  • 46
    • 56749158772 scopus 로고    scopus 로고
    • Nitric oxide specifically inhibits integrin-mediated platelet adhesion and spreading on collagen
    • Roberts W, Riba R, Homer-Vanniasinkam S, Farndale RW, Naseem KM. Nitric oxide specifically inhibits integrin-mediated platelet adhesion and spreading on collagen. J Thromb Haemost. 2008;6(12):2175-85.
    • (2008) J Thromb Haemost , vol.6 , Issue.12 , pp. 2175-2185
    • Roberts, W.1    Riba, R.2    Homer-Vanniasinkam, S.3    Farndale, R.W.4    Naseem, K.M.5
  • 47
    • 0038299375 scopus 로고    scopus 로고
    • Inhaled NO inhibits platelet aggregation and elevates plasma but not intraplatelet cGMP in healthy human volunteers
    • Beghetti M, Sparling C, Cox PN, Stephens D, Adatia I. Inhaled NO inhibits platelet aggregation and elevates plasma but not intraplatelet cGMP in healthy human volunteers. Am J Physiol Heart Circ Physiol. 2003;285(2):H637-42.
    • (2003) Am J Physiol Heart Circ Physiol , vol.285 , Issue.2 , pp. H637-H642
    • Beghetti, M.1    Sparling, C.2    Cox, P.N.3    Stephens, D.4    Adatia, I.5
  • 48
    • 0032554683 scopus 로고    scopus 로고
    • Inhaled nitric oxide inhibits human platelet aggregation, P-selectin expression, and fibrinogen binding in vitro and in vivo
    • Gries A, Bode C, Peter K, Herr A, Bohrer H, Motsch J, et al. Inhaled nitric oxide inhibits human platelet aggregation, P-selectin expression, and fibrinogen binding in vitro and in vivo. Circulation. 1998;97(15):1481-7.
    • (1998) Circulation , vol.97 , Issue.15 , pp. 1481-1487
    • Gries, A.1    Bode, C.2    Peter, K.3    Herr, A.4    Bohrer, H.5    Motsch, J.6
  • 49
    • 70350185413 scopus 로고    scopus 로고
    • Evaluation of the antioxidant activity of non-transformed and transformed pineapple: a comparative study
    • Mhatre M, Tilak-Jain J, De S, Devasagayam TP. Evaluation of the antioxidant activity of non-transformed and transformed pineapple: a comparative study. Food Chem Toxicol. 2009;47(11):2696-702.
    • (2009) Food Chem Toxicol , vol.47 , Issue.11 , pp. 2696-2702
    • Mhatre, M.1    Tilak-Jain, J.2    De, S.3    Devasagayam, T.P.4
  • 50
    • 0034851475 scopus 로고    scopus 로고
    • Flavonoid (myricetin, quercetin, kaempferol, luteolin, and apigenin) content of edible tropical plants
    • Miean KH, Mohamed S. Flavonoid (myricetin, quercetin, kaempferol, luteolin, and apigenin) content of edible tropical plants. J Agric Food Chem. 2001;49(6):3106-12.
    • (2001) J Agric Food Chem , vol.49 , Issue.6 , pp. 3106-3112
    • Miean, K.H.1    Mohamed, S.2
  • 51
    • 40949157010 scopus 로고    scopus 로고
    • Psidium guajava: a review of its traditional uses, phytochemistry and pharmacology
    • Gutierrez RM, Mitchell S, Solis RV. Psidium guajava: a review of its traditional uses, phytochemistry and pharmacology. J Ethnopharmacol. 2008;117(1):1-27.
    • (2008) J Ethnopharmacol , vol.117 , Issue.1 , pp. 1-27
    • Gutierrez, R.M.1    Mitchell, S.2    Solis, R.V.3
  • 52
    • 13244275108 scopus 로고    scopus 로고
    • Ingestion of quercetin inhibits platelet aggregation and essential components of the collagen-stimulated platelet activation pathway in humans
    • Hubbard GP, Wolffram S, Lovegrove JA, Gibbins JM. Ingestion of quercetin inhibits platelet aggregation and essential components of the collagen-stimulated platelet activation pathway in humans. J Thromb Haemost. 2004;2(12):2138-45.
    • (2004) J Thromb Haemost , vol.2 , Issue.12 , pp. 2138-2145
    • Hubbard, G.P.1    Wolffram, S.2    Lovegrove, J.A.3    Gibbins, J.M.4
  • 54
    • 0035201020 scopus 로고    scopus 로고
    • Antiplatelet activity of green tea catechins is mediated by inhibition of cytoplasmic calcium increase
    • Kang W, Chung K, Chung J, Lee J, Park J, Zhang Y, et al. Antiplatelet activity of green tea catechins is mediated by inhibition of cytoplasmic calcium increase. J Cardiovasc Pharmacol. 2001;38(6):875-84.
    • (2001) J Cardiovasc Pharmacol , vol.38 , Issue.6 , pp. 875-884
    • Kang, W.1    Chung, K.2    Chung, J.3    Lee, J.4    Park, J.5    Zhang, Y.6
  • 55
    • 0026490865 scopus 로고
    • Effects of guava intake on serum total and high-density lipoprotein cholesterol levels and on systemic blood pressure
    • Singh RB, Rastogi SS, Singh R, Ghosh S, Niaz MA. Effects of guava intake on serum total and high-density lipoprotein cholesterol levels and on systemic blood pressure. Am J Cardiol. 1992;70(15):1287-91.
    • (1992) Am J Cardiol , vol.70 , Issue.15 , pp. 1287-1291
    • Singh, R.B.1    Rastogi, S.S.2    Singh, R.3    Ghosh, S.4    Niaz, M.A.5
  • 56
    • 33144471473 scopus 로고    scopus 로고
    • Hypoglycemic and hypotensive effects of Psidium guajava Linn. (Myrtaceae) leaf aqueous extract
    • Ojewole JA. Hypoglycemic and hypotensive effects of Psidium guajava Linn. (Myrtaceae) leaf aqueous extract. Methods Find Exp Clin Pharmacol. 2005;27(10):689-95.
    • (2005) Methods Find Exp Clin Pharmacol , vol.27 , Issue.10 , pp. 689-695
    • Ojewole, J.A.1


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