Mendelian Randomization Studies Do Not Support a Role for Vitamin D in Coronary Artery Disease

Circulation: Cardiovascular Genetics

Volumn 9, Issue 4, 2016, Pages 349-356

  Manousaki, Despoina ^a   Mokry, Lauren E ^a   Ross, Stephanie ^a   Goltzman, David ^a,b   Brent Richards, J ^a,b,c,d  

^a MCGILL UNIVERSITY   (Canada)

^b Department of Medicine ^*  (Canada)

^c MCGILL UNIVERSITY   (Canada)

^d KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

coronary artery disease; Genome Wide Association Study; Mendelian randomization analysis; single nucleotide polymorphism; Vitamin D

Indexed keywords

25 HYDROXYVITAMIN D; COLECALCIFEROL 24 HYDROXYLASE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; VITAMIN D; 25-HYDROXYVITAMIN D; BIOLOGICAL MARKER;

ALLELE; ARTICLE; BODY MASS; CARDIOVASCULAR RISK; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DIASTOLIC BLOOD PRESSURE; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HUMAN; HYPERLIPIDEMIA; HYPERTENSION; MAJOR CLINICAL STUDY; MENDELIAN RANDOMIZATION ANALYSIS; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PLEIOTROPY; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTOLIC BLOOD PRESSURE; VITAMIN BLOOD LEVEL; ANALOGS AND DERIVATIVES; BLOOD; CASE CONTROL STUDY; GENE FREQUENCY; GENETIC PREDISPOSITION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; META ANALYSIS; ODDS RATIO; PHENOTYPE; RISK ASSESSMENT; RISK FACTOR; VITAMIN D DEFICIENCY;

BIOMARKERS; CASE-CONTROL STUDIES; CORONARY ARTERY DISEASE; GENE FREQUENCY; GENETIC PLEIOTROPY; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; LINKAGE DISEQUILIBRIUM; MENDELIAN RANDOMIZATION ANALYSIS; ODDS RATIO; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK ASSESSMENT; RISK FACTORS; VITAMIN D; VITAMIN D DEFICIENCY;

EID: 84982310426     PISSN: 1942325X     EISSN: 19423268     Source Type: Journal    
DOI: 10.1161/CIRCGENETICS.116.001396     Document Type: Article

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