Polymorphisms related to the serum 25-Hydroxyvitamin D level and risk of Myocardial infarction, diabetes, cancer and mortality. The Tromsø study

PLoS ONE

Volumn 7, Issue 5, 2012, Pages

  Jorde, Rolf ^a,b   Schirmer, Henrik ^a   Wilsgaard, Tom ^a   Joakimsen, Ragnar Martin ^a,b   Mathiesen, Ellisiv Bøgeberg ^a,b   Njølstad, Inger ^a   Løchen, Maja Lisa ^a   Figenschau, Yngve ^a,b   Berg, Jens Petter ^c   Svartberg, Johan ^a,b   Grimnes, Guri ^a,b  

^a UNIVERSITY OF TROMSØ   (Norway)

^b UNIVERSITY HOSPITAL OF NORTH NORWAY   (Norway)

^c OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIFEDIOL; CYTOCHROME P450; CYTOCHROME P450 24A1; DNA; UNCLASSIFIED DRUG; 25 HYDROXYVITAMIN D; 25-HYDROXYVITAMIN D; DRUG DERIVATIVE; STEROID MONOOXYGENASE; VITAMIN D; VITAMIN D 24 HYDROXYLASE; VITAMIN D 24-HYDROXYLASE;

ALLELE; ARTICLE; CONTROLLED STUDY; CYP24A1 GENE; DISEASE REGISTRY; FEMALE; GENE; GENETIC ASSOCIATION; GENETIC RISK; GENOTYPE; HEART INFARCTION; HUMAN; MAJOR CLINICAL STUDY; MALE; MALIGNANT NEOPLASTIC DISEASE; MORTALITY; NON INSULIN DEPENDENT DIABETES MELLITUS; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM; VITAMIN BLOOD LEVEL; BIOASSAY; BLOOD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; GENETICS; NEOPLASM; NORWAY; RANDOMIZED CONTROLLED TRIAL; REGRESSION ANALYSIS; RISK FACTOR;

DIABETES MELLITUS, TYPE 2; ENDPOINT DETERMINATION; HUMANS; MYOCARDIAL INFARCTION; NEOPLASMS; NORWAY; POLYMORPHISM, SINGLE NUCLEOTIDE; REGRESSION ANALYSIS; RISK FACTORS; STEROID HYDROXYLASES; VITAMIN D;

EID: 84861371583     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0037295     Document Type: Article

References (45)

1. DeLuca HF, (2004) Overview of general physiologic features and functions of vitamin D. Am J Clin Nutr 80: 1689S-1696S.
2. Jorde R, Figenschau Y, Emaus N, Hutchinson M, Grimnes G, (2010) Serum 25-hydroxyvitamin D levels are strongly related to systolic blood pressure but do not predict future hypertension. Hypertension 55: 792-798.
3. Jorde R, Sneve M, Emaus N, Figenschau Y, Grimnes G, (2010) Cross-sectional and longitudinal relation between serum 25-hydroxyvitamin D and body mass index: the Tromsø study. Eur J Nutr 49: 401-407.
4. Hutchinson MS, Figenschau Y, Njølstad I, Schirmer H, Jorde R, (2011) Serum 25-hydroxyvitamin D levels are inversely associated with glycated haemoglobin (HbA(1c)). The Tromsø Study. Scand J Clin Lab Invest 71: 399-406.
5. Jorde R, Figenschau Y, Hutchinson M, Emaus N, Grimnes G, (2010) High serum 25- hydroxyvitamin D concentrations are associated with a favorable serum lipid profile. Eur J Clin Nutr 64: 1457-1464.
6. Grimnes G, Emaus N, Joakimsen RM, Figenschau Y, Jenssen T, et al. (2010) Baseline serum 25-hydroxyvitamin D concentrations in the Tromsø Study 1994-95 and risk of developing type 2 diabetes mellitus during 11 years of follow-up. Diabet Med 27: 1107-1115.
7. Hutchinson MS, Grimnes G, Joakimsen RM, Figenschau Y, Jorde R, (2010) Low serum 25-hydroxyvitamin D levels are associated with increased all-cause mortality risk in a general population: the Tromsø study. Eur J Endocrinol 162: 935-942.
8. Knekt P, Laaksonen M, Mattila C, Härkänen T, Marniemi J, et al. (2008) Serum vitamin D and subsequent occurrence of type 2 diabetes. Epidemiology 19: 666-671.
9. Melamed ML, Michos ED, Post W, Astor B, (2008) 25-hydroxyvitamin D levels and the risk of mortality in the general population. Arch Intern Med 168: 1629-1637.
10. Giovannucci E, Liu Y, Rimm EB, Hollis BW, Fuchs CS, et al. (2006) Prospective study of predictors of vitamin D status and cancer incidence and mortality in men. J Natl Cancer Inst 98: 451-459.
11. Livshits G, Karasik D, Seibel MJ, (1999) Statistical genetic analysis of plasma levels of vitamin D: familial study. Ann Hum Genet 63(Pt 5): 429-439.
12. Hunter D, De Lange M, Snieder H, MacGregor AJ, Swaminathan R, et al. (2001) Genetic contribution to bone metabolism, calcium excretion, and vitamin D and parathyroid hormone regulation. J Bone Miner Res 16: 371-378.
13. Wang TJ, Zhang F, Richards JB, Kestenbaum B, van Meurs JB, et al. (2010) Common genetic determinants of vitamin D insufficiency: a genome-wide association study Lancet 376: 180-188.
14. Ahn J, Yu K, Stolzenberg-Solomon R, Simon KC, McCullough ML, et al. (2010) Genome-wide association study of circulating vitamin D levels. Hum Mol Genet 19: 2739-2745.
15. Thelle DS, Førde OH, Try K, Lehmann EH, (1976) The Tromsø heart study. Methods and main results of the cross-sectional study. Acta Med Scand 200: 107-118.
16. Jacobsen BK, Eggen AE, Mathiesen EB, Wilsgaard T, Njølstad I, (2011) Cohort profile: The Tromso Study. Int J Epidemiol [Epub ahead of print] doi:10.1093/ije/dyr049.
17. Joseph J, Svartberg J, Njølstad I, Schirmer H, (2011) Risk factors of type 2 diabetes in groups stratified according to metabolic syndrome. A 10-year follow-up of The Tromsø Study. Eur J Epidemiol 26: 117-124.
18. Mannsverk J, Wilsgaard T, Njølstad I, Hopstock LA, Løchen ML, et al. (2011) Age and gender differences in incidence and case fatality trends for myocardial infarction: a 30-year follow-up. The Tromso Study. Eur J Cardiovasc Prev Rehabil [Epub ahead of print] doi:10.1177/1741826711421081.
19. Kulathinal S, Karvanen J, Saarela O, Kuulasmaa K, (2007) Case-cohort design in practice-experiences from the MORGAM Project. Epidemiol Perspect Innov 4: 15.
20. Giovannucci E, Liu Y, Hollis BW, Rimm EB, (2008) 25-hydroxyvitamin D and risk of myocardial infarction in men: a prospective study. Arch Intern Med 168: 1174-1180.
21. Grimnes G, Almaas B, Eggen AE, Emaus N, Figenschau Y, et al. (2010) Effect of smoking on the serum levels of 25-hydroxyvitamin D depends on the assay employed. Eur J Endocrinol 163: 339-348.
22. Jorde R, Svartberg J, Sundsfjord J, (2005) Serum parathyroid hormone as a predictor of increase in systolic blood pressure in men. J Hypertens 23: 1639-1644.
23. Bu FX, Armas L, Lappe J, Zhou Y, Gao G, et al. (2010) Comprehensive association analysis of nine candidate genes with serum 25-hydroxy vitamin D levels among healthy Caucasian subjects. Hum Genet 128: 549-556.
24. Shen H, Bielak LF, Ferguson JF, Streeten EA, Yerges-Armstrong LM, et al. (2010) Association of the vitamin D metabolism gene CYP24A1 with coronary artery calcification. Arterioscler Thromb Vasc Biol 30: 2648-2654.
25. Rodriguez S, Gaunt TR, Day IN, (2009) Hardy-Weinberg equilibrium testing of biological ascertainment for Mendelian randomization studies. Am J Epidemiol 169: 505-514.
26. Lewontin RC, (1964) The Interaction of Selection and Linkage. I. General Considerations; Heterotic Models. Genetics 49: 49-67.
27. Gaunt TR, Rodríguez S, Day IN, (2007) Cubic exact solutions for the estimation of pairwise haplotype frequencies: implications for linkage disequilibrium analyses and a web tool 'CubeX'. BMC Bioinformatics 8: 428.
28. Engelman CD, Meyers KJ, Ziegler JT, Taylor KD, Palmer ND, et al. (2010) Genome-wide association study of vitamin D concentrations in Hispanic Americans: the IRAS family study. J Steroid Biochem Mol Biol 122: 186-192.
29. Wang TJ, Pencina MJ, Booth SL, Jacques PF, Ingelsson E, et al. (2008) Vitamin D deficiency and risk of cardiovascular disease. Circulation 117: 503-511.
30. Detrano R, Guerci AD, Carr JJ, Bild DE, Burke G, et al. (2008) Coronary calcium as a predictor of coronary events in four racial or ethnic groups. N Engl J Med 358: 1336-1345.
31. Deeb KK, Trump DL, Johnson CS, (2007) Vitamin D signalling pathways in cancer: potential for anticancer therapeutics. Nat Rev Cancer 7: 684-700.
32. Buttigliero C, Monagheddu C, Petroni P, Saini A, Dogliotti L, et al. (2011) Prognostic role of vitamin d status and efficacy of vitamin d supplementation in cancer patients: a systematic review. Oncologist 16: 1215-1227.
33. Institute of Medicine (US) Committee to Review Dietary Reference Intakes for Vitamin D and Calcium; Ross AC, Taylor CL, Yaktine AL, Del Valle HB, editors 2011 Dietary Reference Intakes for Calcium and Vitamin D. Washington (DC): National Academies Press (US).
34. Ramnath N, Kim S, Christensen PJ, (2011) Vitamin D and lung cancer. Expert Rev Respir Med 5: 305-309.
35. Barnett CM, Beer TM, (2011) Prostate cancer and vitamin d: what does the evidence really suggest? Urol Clin North Am 38: 333-342.
36. Yin L, Grandi N, Raum E, Haug U, Arndt V, et al. (2010) Meta-analysis: serum vitamin D and breast cancer risk. Eur J Cancer 46: 2196-2205.
37. Chen G, Kim SH, King AN, Zhao L, Simpson RU, et al. (2011) CYP24A1 is an independent prognostic marker of survival in patients with lung adenocarcinoma. Clin Cancer Res 17: 817-826.
38. Anderson LN, Cotterchio M, Cole DE, Knight JA, (2011) Vitamin D-related genetic variants, interactions with vitamin D exposure, and breast cancer risk among Caucasian women in Ontario. Cancer Epidemiol Biomarkers Prev 20: 1708-1717.
39. Dorjgochoo T, Delahanty R, Lu W, Long J, Cai Q, et al. (2011) Common Genetic Variants in the Vitamin D Pathway Including Genome-Wide Associated Variants Are Not Associated with Breast Cancer Risk among Chinese Women. Cancer Epidemiol Biomarkers Prev 20: 2313-2316.
40. Ma Y, Zhang P, Wang F, Yang J, Liu Z, et al. (2011) Association Between Vitamin D and Risk of Colorectal Cancer: A Systematic Review of Prospective Studies. J Clin Oncol 29: 3775-3782.
41. Broderstad AR, Smith-Sivertsen T, Dahl IM, Ingebretsen OC, Lund E, (2010) Low prevalence of hereditary hemochromatosis in multiethnic populations in Northern Norway. Scand J Gastroenterol 46: 350-357.
42. NCBI website. 21 Available: http://www.ncbi.nlm.nih.gov/sites/entrez?db=snp. Accessed 2012 Apr.
43. Constans J, Viau M, Bouissou C, (1980) Affinity differences for the 25-OH-D3 associated with the genetic heterogeneity of the vitamin D-binding protein. FEBS Lett 111: 107-111.
44. Zintzaras E, Rodopoulou P, Koukoulis GN, (2006) BsmI, TaqI, ApaI and FokI polymorphisms in the vitamin D receptor (VDR) gene and the risk of osteoporosis: a meta-analysis. Dis Markers 22: 317-326.
45. Cooper JD, Smyth DJ, Walker NM, Stevens H, Burren OS, et al. (2011) Inherited variation in vitamin D genes is associated with predisposition to autoimmune disease type 1 diabetes. Diabetes 60: 1624-1631.