ATF4 gene network mediates cellular response to the anticancer PAD inhibitor YW3-56 in triple-negative breast cancer cells

Molecular Cancer Therapeutics

Volumn 14, Issue 4, 2015, Pages 877-888

  Wang, Shu ^a   Chen, Xiangyun Amy ^a   Hu, Jing ^a   Jiang, Jian Kang ^b   Li, Yunfei ^a,c   Chan Salis, Ka Yim ^a   Gu, Ying ^a   Chen, Gong ^a   Thomas, Craig ^b   Pugh, B Franklin ^a   Wang, Yanming ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c Life Technologies   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; ANTINEOPLASTIC AGENT; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; HYDROLASE INHIBITOR; INITIATION FACTOR 2ALPHA; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PROGESTERONE RECEPTOR; PROTEIN ARGININE DEIMINASE; PROTEIN P53; PUMA PROTEIN; UNCLASSIFIED DRUG; UPSTREAM STIMULATORY FACTOR; YW 3 56; CCAAT ENHANCER BINDING PROTEIN BETA; EIF2AK3 PROTEIN, HUMAN; ENZYME INHIBITOR; HISTONE; HYDROLASE; PROTEIN BINDING; PROTEIN KINASE R; PROTEIN-ARGININE DEIMINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOLYSOSOME; AUTOPHAGOSOME; AUTOPHAGY; BINDING SITE; BREAST CANCER CELL LINE; CANCER INHIBITION; CELL DEATH; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; GENE ACTIVATION; GENE EXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; MICROARRAY ANALYSIS; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PHOSPHORYLATION; REGULATOR GENE; RNA INTERFERENCE; TRANSCRIPTION REGULATION; TRIPLE NEGATIVE BREAST CANCER; TUMOR GROWTH INHIBITION RATE; TUMOR VOLUME; TUMOR XENOGRAFT; ANIMAL; ANTAGONISTS AND INHIBITORS; CLUSTER ANALYSIS; DISEASE MODEL; DRUG EFFECTS; DRUG SCREENING; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENETICS; METABOLISM; MUTATION; NUCLEOTIDE MOTIF; PATHOLOGY; SIGNAL TRANSDUCTION; TRIPLE NEGATIVE BREAST NEOPLASMS; TUMOR CELL LINE;

ACTIVATING TRANSCRIPTION FACTOR 4; ANIMALS; AUTOPHAGY; BINDING SITES; CCAAT-ENHANCER-BINDING PROTEIN-BETA; CELL LINE, TUMOR; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; CLUSTER ANALYSIS; DISEASE MODELS, ANIMAL; EIF-2 KINASE; ENDOPLASMIC RETICULUM STRESS; ENZYME INHIBITORS; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE REGULATORY NETWORKS; HISTONES; HUMANS; HYDROLASES; MICE; MITOCHONDRIA; MUTATION; NUCLEOTIDE MOTIFS; PROTEIN BINDING; SIGNAL TRANSDUCTION; TRIPLE NEGATIVE BREAST NEOPLASMS; TUMOR BURDEN; TUMOR SUPPRESSOR PROTEIN P53; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84982168622     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-14-1093-T     Document Type: Article

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