Novel robust in vitro hepatitis B virus infection model using fresh human hepatocytes isolated from humanized mice

American Journal of Pathology

Volumn 185, Issue 5, 2015, Pages 1275-1285

  Ishida, Yuji ^a,b   Yamasaki, Chihiro ^a   Yanagi, Ami ^a   Yoshizane, Yasumi ^a   Fujikawa, Kazuyuki ^b   Watashi, Koichi ^c   Abe, Hiromi ^b,d   Wakita, Takaji ^c   Hayes, C Nelson ^b,d   Chayama, Kazuaki ^b,d   Tateno, Chise ^a,b  

^a PhoenixBio USA Corporation   (Japan)

^b HIROSHIMA UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^d Institute of Physical and Chemical Research   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CIRCULAR DNA; HEPATITIS B ANTIBODY; HEPATITIS B SURFACE ANTIGEN; LAMIVUDINE; MESSENGER RNA; SMALL INTERFERING RNA; TAUROCHOLIC ACID; VIRUS DNA; VIRUS PROTEIN; VIRUS RNA;

ANIMAL CELL; ARTICLE; CELL ISOLATION; CHILD; CHIMERA; COMPARATIVE STUDY; COVALENT BOND; DOSE RESPONSE; FEMALE; GENE EXPRESSION; HEPATITIS B; HEPATITIS B VIRUS; HEPATITIS B VIRUS GENOTYPE A; HEPATITIS B VIRUS GENOTYPE B; HEPATITIS B VIRUS GENOTYPE C; HEPATITIS B VIRUS GENOTYPE D; HEPATOCELLULAR CARCINOMA CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; INFECTION SENSITIVITY; INOCULATION; LIVER CELL; MALE; MOUSE; NONHUMAN; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN EXPRESSION; REINFECTION; VIRUS ENTRY; VIRUS PARTICLE; VIRUS REPLICATION; ANIMAL; DISEASE MODEL; GENE SILENCING; GROWTH, DEVELOPMENT AND AGING; IMMUNOHISTOCHEMISTRY; INFANT; REAL TIME POLYMERASE CHAIN REACTION; VIROLOGY;

ANIMALS; CHILD, PRESCHOOL; DISEASE MODELS, ANIMAL; DNA, VIRAL; FEMALE; GENE KNOCKDOWN TECHNIQUES; HEPATITIS B; HEPATITIS B VIRUS; HEPATOCYTES; HUMANS; IMMUNOHISTOCHEMISTRY; IN VITRO TECHNIQUES; INFANT; MALE; MICE; REAL-TIME POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; RNA, VIRAL;

EID: 84928037100     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2015.01.028     Document Type: Article

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