Tumour-cell-induced endothelial cell necroptosis via death receptor 6 promotes metastasis

Nature

Volumn 536, Issue 7615, 2016, Pages 215-218

  Strilic, Boris ^a   Yang, Lida ^a   Albarrán Juárez, Julián ^a   Wachsmuth, Laurens ^b   Han, Kang ^c   Müller, Ulrike C ^c   Pasparakis, Manolis ^b   Offermanns, Stefan ^a,d  

^a MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

^b UNIVERSITY OF COLOGNE   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d GOETHE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN; CASPASE 8; DEATH RECEPTOR; DEATH RECEPTOR 6; UNCLASSIFIED DRUG; CASPASE INHIBITOR; IMIDAZOLE DERIVATIVE; INDOLE DERIVATIVE; NECROSTATIN-1; RECEPTOR INTERACTING PROTEIN SERINE THREONINE KINASE; RIPK3 PROTEIN, HUMAN; RIPK3 PROTEIN, MOUSE; TNFRSF21 PROTEIN, HUMAN; TNFRSF21 PROTEIN, MOUSE; TUMOR NECROSIS FACTOR RECEPTOR;

BLOOD; CANCER; CARDIOVASCULAR SYSTEM; CELLS AND CELL COMPONENTS; ENZYME ACTIVITY; PROTEIN; TUMOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MALE; METASTASIS; MOUSE; NECROPTOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR CELL; ANIMAL; ANTAGONISTS AND INHIBITORS; APOPTOSIS; CELL LINE; DEFICIENCY; DISEASE MODEL; DRUG EFFECTS; GENETICS; METABOLISM; NECROSIS; NEOPLASM; NEOPLASM METASTASIS; PATHOLOGY; TRANSENDOTHELIAL AND TRANSEPITHELIAL MIGRATION; UMBILICAL VEIN ENDOTHELIAL CELL;

MURINAE; MUS;

AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; APOPTOSIS; CASPASE 8; CASPASE INHIBITORS; CELL LINE; DISEASE MODELS, ANIMAL; ENDOTHELIAL CELLS; FEMALE; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; IMIDAZOLES; INDOLES; MALE; MICE; NECROSIS; NEOPLASM METASTASIS; NEOPLASMS; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES; RECEPTORS, TUMOR NECROSIS FACTOR; TRANSENDOTHELIAL AND TRANSEPITHELIAL MIGRATION;

EID: 84982142876     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature19076     Document Type: Article

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