-
1
-
-
84862909349
-
Five years of GWAS discovery
-
Visscher, P. M., Brown, M. A., McCarthy, M. I. and Yang, J. (2012) Five years of GWAS discovery. Am. J. Hum. Genet., 90, 7-24
-
(2012)
Am. J. Hum. Genet.
, vol.90
, pp. 7-24
-
-
Visscher, P.M.1
Brown, M.A.2
McCarthy, M.I.3
Yang, J.4
-
2
-
-
0037177527
-
Balancing life-style and genomics research for disease prevention
-
Willett, W. C. (2002) Balancing life-style and genomics research for disease prevention. Science, 296, 695-698
-
(2002)
Science
, vol.296
, pp. 695-698
-
-
Willett, W.C.1
-
3
-
-
0034644185
-
Environmental and heritable factors in the causation of cancer-analyses of cohorts of twins from Sweden
-
Lichtenstein, P., Holm, N. V., Verkasalo, P. K., Iliadou, A., Kaprio, J., Koskenvuo, M., Pukkala, E., Skytthe, A. and Hemminki, K. (2000) Environmental and heritable factors in the causation of cancer-analyses of cohorts of twins from Sweden, Denmark, and Finland. N. Engl. J. Med., 343, 78-85
-
(2000)
Denmark, and Finland. N. Engl. J. Med.
, vol.343
, pp. 78-85
-
-
Lichtenstein, P.1
Holm, N.V.2
Verkasalo, P.K.3
Iliadou, A.4
Kaprio, J.5
Koskenvuo, M.6
Pukkala, E.7
Skytthe, A.8
Hemminki, K.9
-
4
-
-
84871036375
-
Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: A systematic analysis for the Global Burden of Disease Study 2010
-
Lozano, R., Naghavi, M., Foreman, K., et al. (2012) Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet, 380, 2095-2128
-
(2012)
Lancet
, vol.380
, pp. 2095-2128
-
-
Lozano, R.1
Naghavi, M.2
Foreman, K.3
-
5
-
-
84883318855
-
Behavioral and dietary risk factors for noncommunicable diseases
-
Ezzati, M. and Riboli, E. (2013) Behavioral and dietary risk factors for noncommunicable diseases. N. Engl. J. Med., 369, 954-964
-
(2013)
N. Engl. J. Med.
, vol.369
, pp. 954-964
-
-
Ezzati, M.1
Riboli, E.2
-
6
-
-
84906044222
-
Contribution of six risk factors to achieving the 25 × 25 non-communicable disease mortality reduction target: A modelling study
-
Kontis, V., Mathers, C. D., Rehm, J., et al. (2014) Contribution of six risk factors to achieving the 25 × 25 non-communicable disease mortality reduction target: a modelling study. Lancet, 384, 427-437
-
(2014)
Lancet
, vol.384
, pp. 427-437
-
-
Kontis, V.1
Mathers, C.D.2
Rehm, J.3
-
7
-
-
3142740453
-
Spatial epidemiology: Current approaches and future challenges
-
Elliott, P. and Wartenberg, D. (2004) Spatial epidemiology: current approaches and future challenges. Environ. Health Perspect., 112, 998-1006
-
(2004)
Environ. Health Perspect.
, vol.112
, pp. 998-1006
-
-
Elliott, P.1
Wartenberg, D.2
-
8
-
-
84882269987
-
Advancing the application of omics-based biomarkers in environmental epidemiology
-
Vineis, P., van Veldhoven, K., Chadeau-Hyam, M. and Athersuch, T. J (2013) Advancing the application of omics-based biomarkers in environmental epidemiology. Environ. Mol. Mutagen., 54, 461-467
-
(2013)
Environ. Mol. Mutagen.
, vol.54
, pp. 461-467
-
-
Vineis, P.1
Van Veldhoven, K.2
Chadeau-Hyam, M.3
Athersuch, T.J.4
-
9
-
-
23844523425
-
Complementing the genome with an "exposome": The outstanding challenge of environmental exposure measurement in molecular epidemiology
-
Wild, C. P. (2005) Complementing the genome with an "exposome": the outstanding challenge of environmental exposure measurement in molecular epidemiology. Cancer Epidemiol. Biomarkers Prev., 14, 1847-1850
-
(2005)
Cancer Epidemiol. Biomarkers Prev.
, vol.14
, pp. 1847-1850
-
-
Wild, C.P.1
-
10
-
-
78650623080
-
Implications of the exposome for exposure science
-
Rappaport, S. M. (2011) Implications of the exposome for exposure science J. Expo. Sci. Environ. Epidemiol., 21, 5-9
-
(2011)
J. Expo. Sci. Environ. Epidemiol.
, vol.21
, pp. 5-9
-
-
Rappaport, S.M.1
-
11
-
-
84865711795
-
Biomarkers intersect with the exposome
-
Rappaport, S. M. (2012) Biomarkers intersect with the exposome. Biomarkers, 17, 483-489
-
(2012)
Biomarkers
, vol.17
, pp. 483-489
-
-
Rappaport, S.M.1
-
12
-
-
69249115797
-
Building exposure biology centers to put the e into "g x E" interaction studies
-
Smith, M. T. and Rappaport, S. M. (2009) Building exposure biology centers to put the E into "G x E" interaction studies. Environ. Health Perspect., 117, A334-A335
-
(2009)
Environ. Health Perspect.
, vol.117
, pp. A334-A335
-
-
Smith, M.T.1
Rappaport, S.M.2
-
13
-
-
84855992880
-
Discovering environmental causes of disease
-
Rappaport, S. M. (2012) Discovering environmental causes of disease. J Epidemiol. Community Health, 66, 99-102
-
(2012)
J Epidemiol. Community Health
, vol.66
, pp. 99-102
-
-
Rappaport, S.M.1
-
14
-
-
77958192172
-
Epidemiology. Environment and disease risks
-
Rappaport, S. M. and Smith, M. T. (2010) Epidemiology. Environment and disease risks. Science, 330, 460-461
-
(2010)
Science
, vol.330
, pp. 460-461
-
-
Rappaport, S.M.1
Smith, M.T.2
-
15
-
-
80455162391
-
Exposure science and the exposome: An opportunity for coherence in the environmental health sciences
-
Lioy, P. J. and Rappaport, S. M. (2011) Exposure science and the exposome: an opportunity for coherence in the environmental health sciences Environ. Health Perspect., 119, A466-A467
-
(2011)
Environ. Health Perspect.
, vol.119
, pp. A466-A467
-
-
Lioy, P.J.1
Rappaport, S.M.2
-
16
-
-
84891338758
-
The nature of nurture: Refining the definition of the exposome
-
Miller, G. W. and Jones, D. P. (2014) The nature of nurture: refining the definition of the exposome. Toxicol. Sci., 137, 1-2
-
(2014)
Toxicol. Sci.
, vol.137
, pp. 1-2
-
-
Miller, G.W.1
Jones, D.P.2
-
17
-
-
0032168794
-
Systematic functional analysis of the yeast genome
-
Oliver, S. G., Winson, M. K., Kell, D. B. and Baganz, F. (1998) Systematic functional analysis of the yeast genome. Trends Biotechnol., 16, 373-378
-
(1998)
Trends Biotechnol.
, vol.16
, pp. 373-378
-
-
Oliver, S.G.1
Winson, M.K.2
Kell, D.B.3
Baganz, F.4
-
18
-
-
0034959944
-
Combining genomics, metabolome analysis, and biochemical modelling to understand metabolic networks
-
Fiehn, O. (2001) Combining genomics, metabolome analysis, and biochemical modelling to understand metabolic networks. Comp. Funct Genomics, 2, 155-168
-
(2001)
Comp. Funct Genomics
, vol.2
, pp. 155-168
-
-
Fiehn, O.1
-
19
-
-
0032694577
-
'Metabonomics': Understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data
-
Nicholson, J. K., Lindon, J. C. and Holmes, E. (1999) 'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data. Xenobiotica., 29, 1181-1189
-
(1999)
Xenobiotica.
, vol.29
, pp. 1181-1189
-
-
Nicholson, J.K.1
Lindon, J.C.2
Holmes, E.3
-
20
-
-
34247131764
-
Detection of urinary drug metabolite (xenometabolome) signatures in molecular epidemiology studies via statistical total correlation (NMR) spectroscopy
-
Holmes, E., Loo, R. L., Cloarec, O., et al. (2007) Detection of urinary drug metabolite (xenometabolome) signatures in molecular epidemiology studies via statistical total correlation (NMR) spectroscopy. Anal. Chem., 79, 2629-2640
-
(2007)
Anal. Chem.
, vol.79
, pp. 2629-2640
-
-
Holmes, E.1
Loo, R.L.2
Cloarec, O.3
-
22
-
-
84882279485
-
-
Wild, C. P., Scalbert, A. and Herceg, Z. (2013) Measuring the exposome: a powerful basis for evaluating environmental exposures and cancer risk Environ. Mol. Mutagen., 54, 480-499
-
(2013)
Measuring the Exposome: A Powerful Basis for Evaluating Environmental Exposures and Cancer Risk Environ. Mol. Mutagen.
, vol.54
, pp. 480-499
-
-
Wild, C.P.1
Scalbert, A.2
Herceg, Z.3
-
23
-
-
84867340580
-
The role of metabolomics in characterizing the human exposome
-
Athersuch, T. J. (2012) The role of metabolomics in characterizing the human exposome. Bioanalysis, 4, 2207-2212
-
(2012)
Bioanalysis
, vol.4
, pp. 2207-2212
-
-
Athersuch, T.J.1
-
24
-
-
58149202163
-
HMDB: A knowledgebase for the human metabolome
-
Wishart, D. S., Knox, C., Guo, A. C., et al. (2009) HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res., 37, D603-D610
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. D603-D610
-
-
Wishart, D.S.1
Knox, C.2
Guo, A.C.3
-
25
-
-
84876148784
-
-
Wishart, D. S., Jewison, T., Guo, A. C., et al. (2013) HMDB 3.0-The Human Metabolome Database in 2013. Nucleic Acids Res., 41, D801-D807
-
(2013)
HMDB 3.0-The Human Metabolome Database in 2013. Nucleic Acids Res.
, vol.41
, pp. D801-D807
-
-
Wishart, D.S.1
Jewison, T.2
Guo, A.C.3
-
26
-
-
84862198161
-
T3DB: An integrated database for bacterial type III secretion system
-
Wang, Y., Huang, H., Sun, M., Zhang, Q. and Guo, D. (2012) T3DB: an integrated database for bacterial type III secretion system. BMC Bioinformatics, 13, 66
-
(2012)
BMC Bioinformatics
, vol.13
, pp. 66
-
-
Wang, Y.1
Huang, H.2
Sun, M.3
Zhang, Q.4
Guo, D.5
-
27
-
-
84891767304
-
DrugBank 4.0: Shedding new light on drug metabolism
-
Law, V., Knox, C., Djoumbou, Y., et al. (2014) DrugBank 4.0: shedding new light on drug metabolism. Nucleic Acids Res., 42, D1091-D1097
-
(2014)
Nucleic Acids Res.
, vol.42
, pp. D1091-D1097
-
-
Law, V.1
Knox, C.2
Djoumbou, Y.3
-
28
-
-
67849104638
-
PubChem: A public information system for analyzing bioactivities of small molecules
-
Wang, Y., Xiao, J., Suzek, T. O., Zhang, J., Wang, J. and Bryant, S. H (2009) PubChem: a public information system for analyzing bioactivities of small molecules. Nucleic Acids Res., 37, W623-W633
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. W623-W633
-
-
Wang, Y.1
Xiao, J.2
Suzek, T.O.3
Zhang, J.4
Wang, J.5
Bryant, S.H.6
-
29
-
-
78649633211
-
-
Li, Q., Cheng, T., Wang, Y. and Bryant, S. H. (2010) PubChem as a public resource for drug discovery. Drug Discov. Today, 15, 1052-1057
-
(2010)
PubChem As A Public Resource for Drug Discovery. Drug Discov. Today
, vol.15
, pp. 1052-1057
-
-
Li, Q.1
Cheng, T.2
Wang, Y.3
Bryant, S.H.4
-
30
-
-
84862192766
-
ChEMBL: A large-scale bioactivity database for drug discovery
-
Gaulton, A., Bellis, L. J., Bento, A. P., et al. (2012) ChEMBL: a large-scale bioactivity database for drug discovery. Nucleic Acids Res., 40, D1100-D1107
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. D1100-D1107
-
-
Gaulton, A.1
Bellis, L.J.2
Bento, A.P.3
-
31
-
-
0043069547
-
Opinion: Understanding 'global' systems biology: Metabonomics and the continuum of metabolism
-
Nicholson, J. K. and Wilson, I. D. (2003) Opinion: understanding 'global' systems biology: metabonomics and the continuum of metabolism. Nat Rev. Drug Discov., 2, 668-676
-
(2003)
Nat Rev. Drug Discov.
, vol.2
, pp. 668-676
-
-
Nicholson, J.K.1
Wilson, I.D.2
-
32
-
-
84905270662
-
The blood exposome and its role in discovering causes of disease Environ
-
Rappaport, S. M., Barupal, D. K., Wishart, D., Vineis, P. and Scalbert, A (2014) The blood exposome and its role in discovering causes of disease Environ. Health Perspect., 122, 769-774
-
(2014)
Health Perspect.
, vol.122
, pp. 769-774
-
-
Rappaport, S.M.1
Barupal, D.K.2
Wishart, D.3
Vineis, P.4
Scalbert, A.5
-
33
-
-
41149120469
-
Analytical technologies for metabonomics and metabolomics, and multi-omic information recovery
-
Lindon, J. C. and Nicholson, J. K. (2008) Analytical technologies for metabonomics and metabolomics, and multi-omic information recovery Trends Anal. Chem., 27, 194-204
-
(2008)
Trends Anal. Chem.
, vol.27
, pp. 194-204
-
-
Lindon, J.C.1
Nicholson, J.K.2
-
34
-
-
79951892537
-
-
Psychogios, N., Hau, D. D., Peng, J., et al. (2011) The human serum metabolome PLoS One, 6, e16957
-
(2011)
The Human Serum Metabolome PLoS One
, vol.6
, pp. e16957
-
-
Psychogios, N.1
Hau, D.D.2
Peng, J.3
-
35
-
-
84883331522
-
-
Bouatra, S., Aziat, F., Mandal, R., et al. (2013) The human urine metabolome PLoS One, 8, e73076
-
(2013)
The Human Urine Metabolome PLoS One
, vol.8
, pp. e73076
-
-
Bouatra, S.1
Aziat, F.2
Mandal, R.3
-
36
-
-
39149126712
-
Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts
-
Beckonert, O., Keun, H. C., Ebbels, T. M., Bundy, J., Holmes, E., Lindon, J. C. and Nicholson, J. K. (2007) Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts. Nat. Protoc., 2, 2692-2703
-
(2007)
Nat. Protoc.
, vol.2
, pp. 2692-2703
-
-
Beckonert, O.1
Keun, H.C.2
Ebbels, T.M.3
Bundy, J.4
Holmes, E.5
Lindon, J.C.6
Nicholson, J.K.7
-
37
-
-
77952205557
-
-
Want, E. J., Wilson, I. D., Gika, H., Theodoridis, G., Plumb, R. S., Shockcor, J., Holmes, E. and Nicholson, J. K. (2010) Global metabolic profiling procedures for urine using UPLC-MS. Nat. Protoc., 5, 1005-1018
-
(2010)
Global Metabolic Profiling Procedures for Urine Using UPLC-MS. Nat. Protoc.
, vol.5
, pp. 1005-1018
-
-
Want, E.J.1
Wilson, I.D.2
Gika, H.3
Theodoridis, G.4
Plumb, R.S.5
Shockcor, J.6
Holmes, E.7
Nicholson, J.K.8
-
38
-
-
77954731487
-
Evaluation of CE methods for global metabolic profiling of urine
-
Ramautar, R., Toraño, J. S., Somsen, G. W. and de Jong, G. J. (2010) Evaluation of CE methods for global metabolic profiling of urine. Electrophoresis, 31, 2319-2327
-
(2010)
Electrophoresis
, vol.31
, pp. 2319-2327
-
-
Ramautar, R.1
Toraño, J.S.2
Somsen, G.W.3
De Jong, G.J.4
-
39
-
-
78650769334
-
HILIC-UPLC-MS for exploratory urinary metabolic profiling in toxicological studies
-
Spagou, K., Wilson, I. D., Masson, P., et al. (2011) HILIC-UPLC-MS for exploratory urinary metabolic profiling in toxicological studies. Anal Chem., 83, 382-390
-
(2011)
Anal Chem.
, vol.83
, pp. 382-390
-
-
Spagou, K.1
Wilson, I.D.2
Masson, P.3
-
40
-
-
80053427408
-
-
Chan, E. C., Pasikanti, K. K. and Nicholson, J. K. (2011) Global urinary metabolic profiling procedures using gas chromatography-mass spectrometry Nat. Protoc., 6, 1483-1499
-
(2011)
Global Urinary Metabolic Profiling Procedures Using Gas Chromatography-mass Spectrometry Nat. Protoc.
, vol.6
, pp. 1483-1499
-
-
Chan, E.C.1
Pasikanti, K.K.2
Nicholson, J.K.3
-
41
-
-
84864076985
-
-
Roberts, L. D., Souza, A. L., Gerszten, R. E. and Clish, C. B. (2012) Targeted metabolomics. Curr. Protoc. Mol. Biol., 98, 30.2.1-30.2.24
-
(2012)
Targeted Metabolomics. Curr. Protoc. Mol. Biol.
, vol.98
, pp. 3021-30224
-
-
Roberts, L.D.1
Souza, A.L.2
Gerszten, R.E.3
Clish, C.B.4
-
42
-
-
84867376046
-
A QC approach to the determination of day-to-day reproducibility and robustness of LC-MS methods for global metabolite profiling in metabonomics/ metabolomics
-
Gika, H. G., Theodoridis, G. A., Earll, M. and Wilson, I. D. (2012) A QC approach to the determination of day-to-day reproducibility and robustness of LC-MS methods for global metabolite profiling in metabonomics/ metabolomics. Bioanalysis, 4, 2239-2247
-
(2012)
Bioanalysis
, vol.4
, pp. 2239-2247
-
-
Gika, H.G.1
Theodoridis, G.A.2
Earll, M.3
Wilson, I.D.4
-
43
-
-
79959913950
-
Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry
-
Dunn, W. B., Broadhurst, D., Begley, P., et al. (2011) Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry. Nat. Protoc., 6, 1060-1083
-
(2011)
Nat. Protoc.
, vol.6
, pp. 1060-1083
-
-
Dunn, W.B.1
Broadhurst, D.2
Begley, P.3
-
44
-
-
84867341623
-
The importance of experimental design and QC samples in large-scale and MS-driven untargeted metabolomic studies of humans
-
Dunn, W. B., Wilson, I. D., Nicholls, A. W. and Broadhurst, D. (2012) The importance of experimental design and QC samples in large-scale and MS-driven untargeted metabolomic studies of humans. Bioanalysis, 4, 2249-2264
-
(2012)
Bioanalysis
, vol.4
, pp. 2249-2264
-
-
Dunn, W.B.1
Wilson, I.D.2
Nicholls, A.W.3
Broadhurst, D.4
-
45
-
-
33745700684
-
Impact of analytical bias in metabonomic studies of human blood serum and plasma
-
Teahan, O., Gamble, S., Holmes, E., Waxman, J., Nicholson, J. K., Bevan, C. and Keun, H. C. (2006) Impact of analytical bias in metabonomic studies of human blood serum and plasma. Anal. Chem., 78, 4307-4318
-
(2006)
Anal. Chem.
, vol.78
, pp. 4307-4318
-
-
Teahan, O.1
Gamble, S.2
Holmes, E.3
Waxman, J.4
Nicholson, J.K.5
Bevan, C.6
Keun, H.C.7
-
46
-
-
84875900573
-
Performance in omics analyses of blood samples in long-term storage: Opportunities for the exploitation of existing biobanks in environmental health research Environ
-
Hebels, D. G., Georgiadis, P., Keun, H. C., et al. (2013) Performance in omics analyses of blood samples in long-term storage: opportunities for the exploitation of existing biobanks in environmental health research Environ. Health Perspect., 121, 480-487
-
(2013)
Health Perspect.
, vol.121
, pp. 480-487
-
-
Hebels, D.G.1
Georgiadis, P.2
Keun, H.C.3
-
47
-
-
79960130240
-
Differences between human plasma and serum metabolite profiles
-
Yu, Z., Kastenmüller, G., He, Y., et al. (2011) Differences between human plasma and serum metabolite profiles. PLoS One, 6, e21230
-
(2011)
PLoS One
, vol.6
, pp. e21230
-
-
Yu, Z.1
Kastenmüller, G.2
He, Y.3
-
48
-
-
84875106924
-
UPLC-ESI-QTOF/MS and multivariate data analysis for blood plasma and serum metabolomics: Effect of experimental artefacts and anticoagulant
-
Barri, T. and Dragsted, L. O. (2013) UPLC-ESI-QTOF/MS and multivariate data analysis for blood plasma and serum metabolomics: effect of experimental artefacts and anticoagulant. Anal. Chim. Acta, 768, 118-128
-
(2013)
Anal. Chim. Acta
, vol.768
, pp. 118-128
-
-
Barri, T.1
Dragsted, L.O.2
-
49
-
-
77953886372
-
An Environment-Wide Association Study (EWAS) on type 2 diabetes mellitus
-
Patel, C. J., Bhattacharya, J. and Butte, A. J. (2010) An Environment-Wide Association Study (EWAS) on type 2 diabetes mellitus. PLoS One, 5, e10746
-
(2010)
PLoS One
, vol.5
, pp. e10746
-
-
Patel, C.J.1
Bhattacharya, J.2
Butte, A.J.3
-
50
-
-
84862271814
-
Metabolic profiling detects early effects of environmental and lifestyle exposure to cadmium in a human population
-
Ellis, J. K., Athersuch, T. J., Thomas, L. D., et al. (2012) Metabolic profiling detects early effects of environmental and lifestyle exposure to cadmium in a human population. BMC Med., 10, 61
-
(2012)
BMC Med.
, vol.10
, pp. 61
-
-
Ellis, J.K.1
Athersuch, T.J.2
Thomas, L.D.3
-
51
-
-
60749102735
-
-
Thomas, L. D., Hodgson, S., Nieuwenhuijsen, M. and Jarup, L. (2009) Early kidney damage in a population exposed to cadmium and other heavy metals. Environ. Health Perspect., 117, 181-184
-
(2009)
Early Kidney Damage in A Population Exposed to Cadmium and Other Heavy Metals. Environ. Health Perspect.
, vol.117
, pp. 181-184
-
-
Thomas, L.D.1
Hodgson, S.2
Nieuwenhuijsen, M.3
Jarup, L.4
-
52
-
-
79251504951
-
Meetingin- The-middle using metabolic profiling - A strategy for the identification of intermediate biomarkers in cohort studies
-
Chadeau-Hyam, M., Athersuch, T. J., Keun, H. C., et al. (2011) Meetingin- the-middle using metabolic profiling - a strategy for the identification of intermediate biomarkers in cohort studies. Biomarkers, 16, 83-88
-
(2011)
Biomarkers
, vol.16
, pp. 83-88
-
-
Chadeau-Hyam, M.1
Athersuch, T.J.2
Keun, H.C.3
-
53
-
-
79953737332
-
-
Wang, T. J., Larson, M. G., Vasan, R. S., et al. (2011) Metabolite profiles and the risk of developing diabetes. Nat. Med., 17, 448-453
-
(2011)
Metabolite Profiles and the Risk of Developing Diabetes. Nat. Med.
, vol.17
, pp. 448-453
-
-
Wang, T.J.1
Larson, M.G.2
Vasan, R.S.3
-
54
-
-
79953733693
-
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease
-
Wang, Z., Klipfell, E., Bennett, B. J., et al. (2011) Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease. Nature, 472, 57-63
-
(2011)
Nature
, vol.472
, pp. 57-63
-
-
Wang, Z.1
Klipfell, E.2
Bennett, B.J.3
-
55
-
-
84876563088
-
Intestinal microbial metabolism of phosphatidylcholine and cardiovascular risk
-
Tang, W. H., Wang, Z., Levison, B. S., Koeth, R. A., Britt, E. B., Fu, X., Wu, Y. and Hazen, S. L. (2013) Intestinal microbial metabolism of phosphatidylcholine and cardiovascular risk. N. Engl. J. Med., 368, 1575-1584
-
(2013)
N. Engl. J. Med.
, vol.368
, pp. 1575-1584
-
-
Tang, W.H.1
Wang, Z.2
Levison, B.S.3
Koeth, R.A.4
Britt, E.B.5
Fu, X.6
Wu, Y.7
Hazen, S.L.8
-
56
-
-
84877331372
-
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis Nat
-
Koeth, R. A., Wang, Z., Levison, B. S., et al. (2013) Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis Nat. Med., 19, 576-585
-
(2013)
Med.
, vol.19
, pp. 576-585
-
-
Koeth, R.A.1
Wang, Z.2
Levison, B.S.3
-
57
-
-
84910129274
-
γ-Butyrobetaine is a proatherogenic intermediate in gut microbial metabolism of L-carnitine to TMAO
-
Koeth, R. A., Levison, B. S., Culley, M. K., et al. (2014) γ-Butyrobetaine is a proatherogenic intermediate in gut microbial metabolism of L-carnitine to TMAO. Cell Metab., 20, 799-812
-
(2014)
Cell Metab.
, vol.20
, pp. 799-812
-
-
Koeth, R.A.1
Levison, B.S.2
Culley, M.K.3
-
58
-
-
84860223952
-
Genetic determinants of metabolism in health and disease: From biochemical genetics to genome-wide associations
-
Robinette, S. L., Holmes, E., Nicholson, J. K. and Dumas, M. E. (2012) Genetic determinants of metabolism in health and disease: from biochemical genetics to genome-wide associations. Genome Med., 4, 30
-
(2012)
Genome Med.
, vol.4
, pp. 30
-
-
Robinette, S.L.1
Holmes, E.2
Nicholson, J.K.3
Dumas, M.E.4
-
59
-
-
84867744660
-
Genetic variation in metabolic phenotypes: Study designs and applications
-
Suhre, K. and Gieger, C. (2012) Genetic variation in metabolic phenotypes: study designs and applications. Nat. Rev. Genet., 13, 759-769
-
(2012)
Nat. Rev. Genet.
, vol.13
, pp. 759-769
-
-
Suhre, K.1
Gieger, C.2
-
60
-
-
79957604338
-
A genome-wide association study of metabolic traits in human urine
-
Suhre, K., Wallaschofski, H., Raffler, J., et al. (2011) A genome-wide association study of metabolic traits in human urine. Nat. Genet., 43, 565-569
-
(2011)
Nat. Genet.
, vol.43
, pp. 565-569
-
-
Suhre, K.1
Wallaschofski, H.2
Raffler, J.3
-
61
-
-
80052398214
-
Human metabolic individuality in biomedical and pharmaceutical research
-
Suhre, K., Shin, S. Y., Petersen, A. K., et al.; CARDIoGRAM. (2011) Human metabolic individuality in biomedical and pharmaceutical research. Nature, 477, 54-60
-
(2011)
Nature
, vol.477
, pp. 54-60
-
-
Suhre, K.1
Shin, S.Y.2
Petersen, K.A.3
-
62
-
-
75749134031
-
-
Wichmann, H. E., Spector, T. D., Adamski, J. and Suhre, K. (2010) A genome-wide perspective of genetic variation in human metabolism Nature, 42, 137-141
-
(2010)
A Genome-wide Perspective of Genetic Variation in Human Metabolism Nature
, vol.42
, pp. 137-141
-
-
Wichmann, H.E.1
Spector, T.D.2
Adamski, J.3
Suhre, K.4
-
63
-
-
84901686870
-
An atlas of genetic influences on human blood metabolites
-
Shin, S. Y., Fauman, E. B., Petersen, A. K., et al. (2014) An atlas of genetic influences on human blood metabolites. Nat. Genet., 46, 543-550
-
(2014)
Nat. Genet.
, vol.46
, pp. 543-550
-
-
Shin, S.Y.1
Fauman, E.B.2
Petersen, A.K.3
-
64
-
-
84901742293
-
Genome-wide association study of metabolic traits reveals novel gene-metabolite-disease links
-
Rueedi, R., Ledda, M., Nicholls, A. W., et al. (2014) Genome-wide association study of metabolic traits reveals novel gene-metabolite-disease links PLoS Genet., 10, e1004132
-
(2014)
PLoS Genet.
, vol.10
, pp. e1004132
-
-
Rueedi, R.1
Ledda, M.2
Nicholls, A.W.3
-
65
-
-
84897372328
-
Epigenetics meets metabolomics: An epigenome-wide association study with blood serum metabolic traits
-
Petersen, A. K., Zeilinger, S., Kastenmüller, G., et al. (2014) Epigenetics meets metabolomics: an epigenome-wide association study with blood serum metabolic traits. Hum. Mol. Genet., 23, 534-545
-
(2014)
Hum. Mol. Genet.
, vol.23
, pp. 534-545
-
-
Petersen, A.K.1
Zeilinger, S.2
Kastenmüller, G.3
-
66
-
-
84901796976
-
The HELIX Project: Tracking the exposome in real time Environ
-
Potera, C. (2014) The HELIX Project: tracking the exposome in real time Environ. Health Perspect., 122, A169
-
(2014)
Health Perspect.
, vol.122
, pp. A169
-
-
Potera, C.1
-
67
-
-
84901760450
-
The human early-life exposome (HELIX): Project rationale and design
-
Vrijheid, M., Slama, R., Robinson, O., et al. (2014) The human early-life exposome (HELIX): project rationale and design. Environ. Health Perspect., 122, 535-544
-
(2014)
Environ. Health Perspect.
, vol.122
, pp. 535-544
-
-
Vrijheid, M.1
Slama, R.2
Robinson, O.3
-
68
-
-
38949210993
-
Metabolic profiling by ion mobility mass spectrometry (IMMS)
-
Dwivedi, P., Wu, P., Klopsch, S. J., Puzon, G. J., Xun, L. and Hill, H. H., Jr (2008) Metabolic profiling by ion mobility mass spectrometry (IMMS) Metabolomics, 4, 63-80
-
(2008)
Metabolomics
, vol.4
, pp. 63-80
-
-
Dwivedi, P.1
Wu, P.2
Klopsch, S.J.3
Puzon, G.J.4
Xun, L.5
Hill, H.H.6
-
69
-
-
48949106229
-
An approach to enhancing coverage of the urinary metabonome using liquid chromatography-ion mobility-mass spectrometry
-
Harry, E. L., Weston, D. J., Bristow, A. W., Wilson, I. D. and Creaser, C. S (2008) An approach to enhancing coverage of the urinary metabonome using liquid chromatography-ion mobility-mass spectrometry. J. Chromatogr B. Analyt. Technol. Biomed. Life Sci., 871, 357-361
-
(2008)
J. Chromatogr B. Analyt. Technol. Biomed. Life Sci.
, vol.871
, pp. 357-361
-
-
Harry, E.L.1
Weston, D.J.2
Bristow, A.W.3
Wilson, I.D.4
Creaser, C.S.5
-
70
-
-
84857124907
-
The human circadian metabolome
-
Dallmann, R., Viola, A. U., Tarokh, L., Cajochen, C. and Brown, S. A (2012) The human circadian metabolome. Proc. Natl. Acad. Sci. U. S. A., 109, 2625-2629
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. 2625-2629
-
-
Dallmann, R.1
Viola, A.U.2
Tarokh, L.3
Cajochen, C.4
Brown, S.A.5
-
71
-
-
84904704346
-
Effect of sleep deprivation on the human metabolome
-
Davies, S. K., Ang, J. E., Revell, V. L., et al. (2014) Effect of sleep deprivation on the human metabolome. Proc. Natl. Acad. Sci. U. S. A., 111, 10761-10766.
-
(2014)
Proc. Natl. Acad. Sci. U. S. A.
, vol.111
, pp. 10761-10766
-
-
Davies, S.K.1
Ang, J.E.2
Revell, V.L.3
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