-
1
-
-
57149114936
-
Genetics meets metabolomics: A genome-wide association study of metabolite profiles in human serum
-
Gieger, C. et al. Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum. PLoS Genet. 4, e1000282 (2008).
-
(2008)
PLoS Genet.
, vol.4
-
-
Gieger, C.1
-
2
-
-
75749134031
-
A genome-wide perspective of genetic variation in human metabolism
-
Illig, T. et al. A genome-wide perspective of genetic variation in human metabolism. Nat. Genet. 42, 137-141 (2010).
-
(2010)
Nat. Genet.
, vol.42
, pp. 137-141
-
-
Illig, T.1
-
3
-
-
59249096217
-
Genome-wide association study of plasma polyunsaturated fatty acids in the InCHIANTI Study
-
Tanaka, T. et al. Genome-wide association study of plasma polyunsaturated fatty acids in the InCHIANTI Study. PLoS Genet. 5, e1000338 (2009).
-
(2009)
PLoS Genet.
, vol.5
-
-
Tanaka, T.1
-
4
-
-
73449117605
-
Genetic determinants of circulating sphingolipid concentrations in European populations
-
Hicks, A.A. et al. Genetic determinants of circulating sphingolipid concentrations in European populations. PLoS Genet. 5, e1000672 (2009).
-
(2009)
PLoS Genet.
, vol.5
-
-
Hicks, A.A.1
-
5
-
-
33745700438
-
Targeted profiling: Quantitative analysis of 1H NMR metabolomics data
-
Weljie, A.M., Newton, J., Mercier, P., Carlson, E. & Slupsky, C.M. Targeted profiling: quantitative analysis of 1H NMR metabolomics data. Anal. Chem. 78, 4430-4442 (2006).
-
(2006)
Anal. Chem.
, vol.78
, pp. 4430-4442
-
-
Weljie, A.M.1
Newton, J.2
Mercier, P.3
Carlson, E.4
Slupsky, C.M.5
-
6
-
-
46349084465
-
Bioinformatics analysis of targeted metabolomics - Uncovering old and new tales of diabetic mice under medication
-
DOI 10.1210/en.2007-1747
-
Altmaier, E. et al. Bioinformatics analysis of targeted metabolomics-uncovering old and new tales of diabetic mice under medication. Endocrinology 149, 3478-3489 (2008). (Pubitemid 351919596)
-
(2008)
Endocrinology
, vol.149
, Issue.7
, pp. 3478-3489
-
-
Altmaier, E.1
Ramsay, S.L.2
Graber, A.3
Mewes, H.-W.4
Weinberger, K.M.5
Suhre, K.6
-
7
-
-
78649735772
-
Metabolic footprint of diabetes: A multiplatform metabolomics study in an epidemiological setting
-
Suhre, K. et al. Metabolic footprint of diabetes: a multiplatform metabolomics study in an epidemiological setting. PLoS ONE 5, e13953 (2010).
-
(2010)
PLoS ONE
, vol.5
-
-
Suhre, K.1
-
8
-
-
0000279797
-
β-Aminoisobutyric acid (α-methyl-β-alanine); A new amino-acid obtained from human urine
-
Crumpler, H.R., Dent, C.E., Harris, H. & Westall, R.G. β-Aminoisobutyric acid (α-methyl-β-alanine); a new amino-acid obtained from human urine. Nature 167, 307-308 (1951).
-
(1951)
Nature
, vol.167
, pp. 307-308
-
-
Crumpler, H.R.1
Dent, C.E.2
Harris, H.3
Westall, R.G.4
-
9
-
-
0345910237
-
Family studies on the urinary excretion of beta-aminoisobutyric acid
-
Harris, H. Family studies on the urinary excretion of beta-aminoisobutyric acid. Ann. Eugen. 18, 43-49 (1953).
-
(1953)
Ann. Eugen.
, vol.18
, pp. 43-49
-
-
Harris, H.1
-
10
-
-
0014487750
-
Genetic study of beta-aminoisobutyric acid excretion by Japanese
-
Yanai, J., Kakimoto, Y., Tsujio, T. & Sano, I. Genetic study of beta-aminoisobutyric acid excretion by Japanese. Am. J. Hum. Genet. 21, 115-132 (1969).
-
(1969)
Am. J. Hum. Genet.
, vol.21
, pp. 115-132
-
-
Yanai, J.1
Kakimoto, Y.2
Tsujio, T.3
Sano, I.4
-
11
-
-
0014689925
-
Pyruvate aminotransferase in mammalian liver and excretion of beta-aminoisobutyrate by man
-
Kakimoto, Y., Taniguchi, K. & Sano, I. D-beta-aminoisobutyrate: pyruvate aminotransferase in mammalian liver and excretion of beta-aminoisobutyrate by man. J. Biol. Chem. 244, 335-340 (1969).
-
(1969)
J. Biol. Chem.
, vol.244
, pp. 335-340
-
-
Kakimoto, Y.1
Taniguchi, K.2
D-Beta-Aminoisobutyrate, S.I.3
-
12
-
-
9444252988
-
β-Ureidopropionase deficiency: An inborn error of pyrimidine degradation associated with neurological abnormalities
-
van Kuilenburg, A.B. et al. β-Ureidopropionase deficiency: an inborn error of pyrimidine degradation associated with neurological abnormalities. Hum. Mol. Genet. 13, 2793-2801 (2004).
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 2793-2801
-
-
Van Kuilenburg, A.B.1
-
13
-
-
0000913280
-
Disorders of omega-amino acids in free and peptide-linked forms
-
eds. Scriver, C.R., Beaudet, A.L., Sly, W.S. & Valle, D. McGraw-Hill, New York
-
Scriver, C.R. & Perry, T.L. Disorders of omega-amino acids in free and peptide-linked forms. in The Metabolic Basis of Inherited Disease Vol. I (eds. Scriver, C.R., Beaudet, A.L., Sly, W.S. & Valle, D.) 755-771 (McGraw-Hill, New York, 1989).
-
(1989)
The Metabolic Basis of Inherited Disease i
, pp. 755-771
-
-
Scriver, C.R.1
Perry, T.L.2
-
14
-
-
77949313676
-
Human alanine-glyoxylate aminotransferase 2 lowers asymmetric dimethylarginine and protects from inhibition of nitric oxide production
-
Rodionov, R.N., Murry, D.J., Vaulman, S.F., Stevens, J.W. & Lentz, S.R. Human alanine-glyoxylate aminotransferase 2 lowers asymmetric dimethylarginine and protects from inhibition of nitric oxide production. J. Biol. Chem. 285, 5385-5391 (2010).
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 5385-5391
-
-
Rodionov, R.N.1
Murry, D.J.2
Vaulman, S.F.3
Stevens, J.W.4
Lentz, S.R.5
-
15
-
-
77953501978
-
Association between exaggerated blood pressure response to exercise and serum asymmetric dimethylarginine levels
-
Kayrak, M. et al. Association between exaggerated blood pressure response to exercise and serum asymmetric dimethylarginine levels. Circ. J. 74, 1135-1141 (2010).
-
(2010)
Circ. J.
, vol.74
, pp. 1135-1141
-
-
Kayrak, M.1
-
16
-
-
54149088882
-
Differential effects of arginine methylation on diastolic dysfunction and disease progression in patients with chronic systolic heart failure
-
Wilson Tang, W.H. et al. Differential effects of arginine methylation on diastolic dysfunction and disease progression in patients with chronic systolic heart failure. Eur. Heart J. 29, 2506-2513 (2008).
-
(2008)
Eur. Heart J.
, vol.29
, pp. 2506-2513
-
-
Wilson Tang, W.H.1
-
17
-
-
0026548912
-
Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure
-
Vallance, P., Leone, A., Calver, A., Collier, J. & Moncada, S. Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure. Lancet 339, 572-575 (1992).
-
(1992)
Lancet
, vol.339
, pp. 572-575
-
-
Vallance, P.1
Leone, A.2
Calver, A.3
Collier, J.4
Moncada, S.5
-
18
-
-
27444444747
-
Asymmetric dimethylarginine and progression of chronic kidney disease: The mild to moderate kidney disease study
-
DOI 10.1681/ASN.2005020179
-
Fliser, D. et al. Asymmetric dimethylarginine and progression of chronic kidney disease: the mild to moderate kidney disease study. J. Am. Soc. Nephrol. 16, 2456-2461 (2005). (Pubitemid 41725064)
-
(2005)
Journal of the American Society of Nephrology
, vol.16
, Issue.8
, pp. 2456-2461
-
-
Fliser, D.1
Kronenberg, F.2
Kielstein, J.T.3
Morath, C.4
Bode-Boger, S.M.5
Haller, H.6
Ritz, E.7
-
19
-
-
28444435118
-
Asymmetrical dimethylarginine predicts progression to dialysis and death in patients with chronic kidney disease: A competing risks modeling approach
-
DOI 10.1681/ASN.2005010076
-
Ravani, P. et al. Asymmetrical dimethylarginine predicts progression to dialysis and death in patients with chronic kidney disease: a competing risks modeling approach. J. Am. Soc. Nephrol. 16, 2449-2455 (2005). (Pubitemid 41725063)
-
(2005)
Journal of the American Society of Nephrology
, vol.16
, Issue.8
, pp. 2449-2455
-
-
Ravani, P.1
Tripepi, G.2
Malberti, F.3
Testa, S.4
Mallamaci, F.5
Zoccali, C.6
-
20
-
-
33847005404
-
Disruption of methylarginine metabolism impairs vascular homeostasis
-
Leiper, J. et al. Disruption of methylarginine metabolism impairs vascular homeostasis. Nat. Med. 13, 198-203 (2007).
-
(2007)
Nat. Med.
, vol.13
, pp. 198-203
-
-
Leiper, J.1
-
21
-
-
34548721074
-
Joint effects of the N-acetyltransferase 1 and 2 (NAT1 and NAT2) genes and smoking on bladder carcinogenesis: A literature-based systematic HuGE review and evidence synthesis
-
DOI 10.1093/aje/kwm167
-
Sanderson, S., Salanti, G. & Higgins, J. Joint effects of the N-acetyltransferase 1 and 2 (NAT1 and NAT2) genes and smoking on bladder carcinogenesis: a literature-based systematic HuGE review and evidence synthesis. Am. J. Epidemiol. 166, 741-751 (2007). (Pubitemid 47428907)
-
(2007)
American Journal of Epidemiology
, vol.166
, Issue.7
, pp. 741-751
-
-
Sanderson, S.1
Salanti, G.2
Higgins, J.3
-
22
-
-
77952886405
-
A pharmacogenetic study of docetaxel and thalidomide in patients with castration-resistant prostate cancer using the DMET genotyping platform
-
Deeken, J.F. et al. A pharmacogenetic study of docetaxel and thalidomide in patients with castration-resistant prostate cancer using the DMET genotyping platform. Pharmacogenomics J. 10, 191-199 (2010).
-
(2010)
Pharmacogenomics J.
, vol.10
, pp. 191-199
-
-
Deeken, J.F.1
-
23
-
-
77955505564
-
Biological, clinical and population relevance of 95 loci for blood lipids
-
Teslovich, T.M. et al. Biological, clinical and population relevance of 95 loci for blood lipids. Nature 466, 707-713 (2010).
-
(2010)
Nature
, vol.466
, pp. 707-713
-
-
Teslovich, T.M.1
-
24
-
-
77951553451
-
Drug-induced liver injury: Past, present and future
-
Daly, A.K. Drug-induced liver injury: past, present and future. Pharmacogenomics 11, 607-611 (2010).
-
(2010)
Pharmacogenomics
, vol.11
, pp. 607-611
-
-
Daly, A.K.1
-
25
-
-
70350644759
-
A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium
-
Soranzo, N. et al. A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. Nat. Genet. 41, 1182-1190 (2009).
-
(2009)
Nat. Genet.
, vol.41
, pp. 1182-1190
-
-
Soranzo, N.1
-
28
-
-
33745080967
-
Renal crystal deposits and histopathology in patients with cystine stones
-
DOI 10.1038/sj.ki.5000268, PII 5000268
-
Evan, A.P. et al. Renal crystal deposits and histopathology in patients with cystine stones. Kidney Int. 69, 2227-2235 (2006). (Pubitemid 43882110)
-
(2006)
Kidney International
, vol.69
, Issue.12
, pp. 2227-2235
-
-
Evan, A.P.1
Coe, F.L.2
Lingeman, J.E.3
Shao, Y.4
Matlaga, B.R.5
Kim, S.C.6
Bledsoe, S.B.7
Sommer, A.J.8
Grynpas, M.9
Phillips, C.L.10
Worcester, E.M.11
-
29
-
-
77951766263
-
New loci associated with kidney function and chronic kidney disease
-
Köttgen, A. et al. New loci associated with kidney function and chronic kidney disease. Nat. Genet. 42, 376-384 (2010).
-
(2010)
Nat. Genet.
, vol.42
, pp. 376-384
-
-
Köttgen, A.1
-
30
-
-
77951768942
-
Genetic loci influencing kidney function and chronic kidney disease
-
Chambers, J.C. et al. Genetic loci influencing kidney function and chronic kidney disease. Nat. Genet. 42, 373-375 (2010).
-
(2010)
Nat. Genet.
, vol.42
, pp. 373-375
-
-
Chambers, J.C.1
-
31
-
-
15744405825
-
Identification of mammalian proline transporter SIT1 (SLC6A20) with characteristics of classical system imino
-
DOI 10.1074/jbc.M413027200
-
Takanaga, H., Mackenzie, B., Suzuki, Y. & Hediger, M.A. Identification of mammalian proline transporter SIT1 (SLC6A20) with characteristics of classical system imino. J. Biol. Chem. 280, 8974-8984 (2005). (Pubitemid 40409589)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.10
, pp. 8974-8984
-
-
Takanaga, H.1
Mackenzie, B.2
Suzuki, Y.3
Hediger, M.A.4
-
32
-
-
57449088245
-
Iminoglycinuria and hyperglycinuria are discrete human phenotypes resulting from complex mutations in proline and glycine transporters
-
Bröer, S. et al. Iminoglycinuria and hyperglycinuria are discrete human phenotypes resulting from complex mutations in proline and glycine transporters. J. Clin. Invest. 118, 3881-3892 (2008).
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 3881-3892
-
-
Bröer, S.1
-
33
-
-
79953680469
-
Cohort profile: The Study of Health in Pomerania
-
Volzke, H. et al. Cohort profile: the Study of Health in Pomerania. Int. J. Epidemiol. 40, 294-307 (2011).
-
(2011)
Int. J. Epidemiol.
, vol.40
, pp. 294-307
-
-
Volzke, H.1
-
34
-
-
0034884907
-
Study of Health in Pomerania (SHIP): A health examination survey in an east German region: Objectives and design
-
DOI 10.1007/BF01324255
-
John, U. et al. Study of Health In Pomerania (SHIP): a health examination survey in an east German region: objectives and design. Soz. Praventivmed. 46, 186-194 (2001). (Pubitemid 32747278)
-
(2001)
Sozial- und Praventivmedizin
, vol.46
, Issue.3
, pp. 186-194
-
-
John, U.1
Hensel, E.2
Ludemann, J.3
Piek, M.4
Sauer, S.5
Adam, C.6
Born, G.7
Alte, D.8
Greiser, E.9
Haertel, U.10
Hense, H.-W.11
Haerting, J.12
Willich, S.13
Kessler, C.14
-
35
-
-
34548292504
-
PLINK: A tool set for whole-genome association and population-based linkage analyses
-
DOI 10.1086/519795
-
Purcell, S. et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am. J. Hum. Genet. 81, 559-575 (2007). (Pubitemid 47330214)
-
(2007)
American Journal of Human Genetics
, vol.81
, Issue.3
, pp. 559-575
-
-
Purcell, S.1
Neale, B.2
Todd-Brown, K.3
Thomas, L.4
Ferreira, M.A.R.5
Bender, D.6
Maller, J.7
Sklar, P.8
De Bakker, P.I.W.9
Daly, M.J.10
Sham, P.C.11
|