메뉴 건너뛰기




Volumn 43, Issue 6, 2011, Pages 565-569

A genome-wide association study of metabolic traits in human urine

(24)  Suhre, Karsten a,b,g   Wallaschofski, Henri c   Raffler, Johannes a,b   Friedrich, Nele c   Haring, Robin c   Michael, Kathrin c   Wasner, Christina c   Krebs, Alexander c   Kronenberg, Florian d   Chang, David e   Meisinger, Christa a   Wichmann, H Erich a,b,f   Hoffmann, Wolfgang c   Völzke, Henry c   Völker, Uwe c   Teumer, Alexander c   Biffar, Reiner c   Kocher, Thomas c   Felix, Stephan B c   Illig, Thomas a   more..


Author keywords

[No Author keywords available]

Indexed keywords

ALANINE GLYOXYLATE AMINOTRANSFERASE; ALANINE GLYOXYLATE AMINOTRANSFERASE 2; ARYLAMINE ACETYLTRANSFERASE; MEMBRANE PROTEIN; SLC6A20 PROTEIN; SLC7A9 PROTEIN; UNCLASSIFIED DRUG;

EID: 79957604338     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.837     Document Type: Article
Times cited : (212)

References (35)
  • 1
    • 57149114936 scopus 로고    scopus 로고
    • Genetics meets metabolomics: A genome-wide association study of metabolite profiles in human serum
    • Gieger, C. et al. Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum. PLoS Genet. 4, e1000282 (2008).
    • (2008) PLoS Genet. , vol.4
    • Gieger, C.1
  • 2
    • 75749134031 scopus 로고    scopus 로고
    • A genome-wide perspective of genetic variation in human metabolism
    • Illig, T. et al. A genome-wide perspective of genetic variation in human metabolism. Nat. Genet. 42, 137-141 (2010).
    • (2010) Nat. Genet. , vol.42 , pp. 137-141
    • Illig, T.1
  • 3
    • 59249096217 scopus 로고    scopus 로고
    • Genome-wide association study of plasma polyunsaturated fatty acids in the InCHIANTI Study
    • Tanaka, T. et al. Genome-wide association study of plasma polyunsaturated fatty acids in the InCHIANTI Study. PLoS Genet. 5, e1000338 (2009).
    • (2009) PLoS Genet. , vol.5
    • Tanaka, T.1
  • 4
    • 73449117605 scopus 로고    scopus 로고
    • Genetic determinants of circulating sphingolipid concentrations in European populations
    • Hicks, A.A. et al. Genetic determinants of circulating sphingolipid concentrations in European populations. PLoS Genet. 5, e1000672 (2009).
    • (2009) PLoS Genet. , vol.5
    • Hicks, A.A.1
  • 5
    • 33745700438 scopus 로고    scopus 로고
    • Targeted profiling: Quantitative analysis of 1H NMR metabolomics data
    • Weljie, A.M., Newton, J., Mercier, P., Carlson, E. & Slupsky, C.M. Targeted profiling: quantitative analysis of 1H NMR metabolomics data. Anal. Chem. 78, 4430-4442 (2006).
    • (2006) Anal. Chem. , vol.78 , pp. 4430-4442
    • Weljie, A.M.1    Newton, J.2    Mercier, P.3    Carlson, E.4    Slupsky, C.M.5
  • 6
    • 46349084465 scopus 로고    scopus 로고
    • Bioinformatics analysis of targeted metabolomics - Uncovering old and new tales of diabetic mice under medication
    • DOI 10.1210/en.2007-1747
    • Altmaier, E. et al. Bioinformatics analysis of targeted metabolomics-uncovering old and new tales of diabetic mice under medication. Endocrinology 149, 3478-3489 (2008). (Pubitemid 351919596)
    • (2008) Endocrinology , vol.149 , Issue.7 , pp. 3478-3489
    • Altmaier, E.1    Ramsay, S.L.2    Graber, A.3    Mewes, H.-W.4    Weinberger, K.M.5    Suhre, K.6
  • 7
    • 78649735772 scopus 로고    scopus 로고
    • Metabolic footprint of diabetes: A multiplatform metabolomics study in an epidemiological setting
    • Suhre, K. et al. Metabolic footprint of diabetes: a multiplatform metabolomics study in an epidemiological setting. PLoS ONE 5, e13953 (2010).
    • (2010) PLoS ONE , vol.5
    • Suhre, K.1
  • 8
    • 0000279797 scopus 로고
    • β-Aminoisobutyric acid (α-methyl-β-alanine); A new amino-acid obtained from human urine
    • Crumpler, H.R., Dent, C.E., Harris, H. & Westall, R.G. β-Aminoisobutyric acid (α-methyl-β-alanine); a new amino-acid obtained from human urine. Nature 167, 307-308 (1951).
    • (1951) Nature , vol.167 , pp. 307-308
    • Crumpler, H.R.1    Dent, C.E.2    Harris, H.3    Westall, R.G.4
  • 9
    • 0345910237 scopus 로고
    • Family studies on the urinary excretion of beta-aminoisobutyric acid
    • Harris, H. Family studies on the urinary excretion of beta-aminoisobutyric acid. Ann. Eugen. 18, 43-49 (1953).
    • (1953) Ann. Eugen. , vol.18 , pp. 43-49
    • Harris, H.1
  • 10
    • 0014487750 scopus 로고
    • Genetic study of beta-aminoisobutyric acid excretion by Japanese
    • Yanai, J., Kakimoto, Y., Tsujio, T. & Sano, I. Genetic study of beta-aminoisobutyric acid excretion by Japanese. Am. J. Hum. Genet. 21, 115-132 (1969).
    • (1969) Am. J. Hum. Genet. , vol.21 , pp. 115-132
    • Yanai, J.1    Kakimoto, Y.2    Tsujio, T.3    Sano, I.4
  • 11
    • 0014689925 scopus 로고
    • Pyruvate aminotransferase in mammalian liver and excretion of beta-aminoisobutyrate by man
    • Kakimoto, Y., Taniguchi, K. & Sano, I. D-beta-aminoisobutyrate: pyruvate aminotransferase in mammalian liver and excretion of beta-aminoisobutyrate by man. J. Biol. Chem. 244, 335-340 (1969).
    • (1969) J. Biol. Chem. , vol.244 , pp. 335-340
    • Kakimoto, Y.1    Taniguchi, K.2    D-Beta-Aminoisobutyrate, S.I.3
  • 12
    • 9444252988 scopus 로고    scopus 로고
    • β-Ureidopropionase deficiency: An inborn error of pyrimidine degradation associated with neurological abnormalities
    • van Kuilenburg, A.B. et al. β-Ureidopropionase deficiency: an inborn error of pyrimidine degradation associated with neurological abnormalities. Hum. Mol. Genet. 13, 2793-2801 (2004).
    • (2004) Hum. Mol. Genet. , vol.13 , pp. 2793-2801
    • Van Kuilenburg, A.B.1
  • 13
    • 0000913280 scopus 로고
    • Disorders of omega-amino acids in free and peptide-linked forms
    • eds. Scriver, C.R., Beaudet, A.L., Sly, W.S. & Valle, D. McGraw-Hill, New York
    • Scriver, C.R. & Perry, T.L. Disorders of omega-amino acids in free and peptide-linked forms. in The Metabolic Basis of Inherited Disease Vol. I (eds. Scriver, C.R., Beaudet, A.L., Sly, W.S. & Valle, D.) 755-771 (McGraw-Hill, New York, 1989).
    • (1989) The Metabolic Basis of Inherited Disease i , pp. 755-771
    • Scriver, C.R.1    Perry, T.L.2
  • 14
    • 77949313676 scopus 로고    scopus 로고
    • Human alanine-glyoxylate aminotransferase 2 lowers asymmetric dimethylarginine and protects from inhibition of nitric oxide production
    • Rodionov, R.N., Murry, D.J., Vaulman, S.F., Stevens, J.W. & Lentz, S.R. Human alanine-glyoxylate aminotransferase 2 lowers asymmetric dimethylarginine and protects from inhibition of nitric oxide production. J. Biol. Chem. 285, 5385-5391 (2010).
    • (2010) J. Biol. Chem. , vol.285 , pp. 5385-5391
    • Rodionov, R.N.1    Murry, D.J.2    Vaulman, S.F.3    Stevens, J.W.4    Lentz, S.R.5
  • 15
    • 77953501978 scopus 로고    scopus 로고
    • Association between exaggerated blood pressure response to exercise and serum asymmetric dimethylarginine levels
    • Kayrak, M. et al. Association between exaggerated blood pressure response to exercise and serum asymmetric dimethylarginine levels. Circ. J. 74, 1135-1141 (2010).
    • (2010) Circ. J. , vol.74 , pp. 1135-1141
    • Kayrak, M.1
  • 16
    • 54149088882 scopus 로고    scopus 로고
    • Differential effects of arginine methylation on diastolic dysfunction and disease progression in patients with chronic systolic heart failure
    • Wilson Tang, W.H. et al. Differential effects of arginine methylation on diastolic dysfunction and disease progression in patients with chronic systolic heart failure. Eur. Heart J. 29, 2506-2513 (2008).
    • (2008) Eur. Heart J. , vol.29 , pp. 2506-2513
    • Wilson Tang, W.H.1
  • 17
    • 0026548912 scopus 로고
    • Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure
    • Vallance, P., Leone, A., Calver, A., Collier, J. & Moncada, S. Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure. Lancet 339, 572-575 (1992).
    • (1992) Lancet , vol.339 , pp. 572-575
    • Vallance, P.1    Leone, A.2    Calver, A.3    Collier, J.4    Moncada, S.5
  • 19
    • 28444435118 scopus 로고    scopus 로고
    • Asymmetrical dimethylarginine predicts progression to dialysis and death in patients with chronic kidney disease: A competing risks modeling approach
    • DOI 10.1681/ASN.2005010076
    • Ravani, P. et al. Asymmetrical dimethylarginine predicts progression to dialysis and death in patients with chronic kidney disease: a competing risks modeling approach. J. Am. Soc. Nephrol. 16, 2449-2455 (2005). (Pubitemid 41725063)
    • (2005) Journal of the American Society of Nephrology , vol.16 , Issue.8 , pp. 2449-2455
    • Ravani, P.1    Tripepi, G.2    Malberti, F.3    Testa, S.4    Mallamaci, F.5    Zoccali, C.6
  • 20
    • 33847005404 scopus 로고    scopus 로고
    • Disruption of methylarginine metabolism impairs vascular homeostasis
    • Leiper, J. et al. Disruption of methylarginine metabolism impairs vascular homeostasis. Nat. Med. 13, 198-203 (2007).
    • (2007) Nat. Med. , vol.13 , pp. 198-203
    • Leiper, J.1
  • 21
    • 34548721074 scopus 로고    scopus 로고
    • Joint effects of the N-acetyltransferase 1 and 2 (NAT1 and NAT2) genes and smoking on bladder carcinogenesis: A literature-based systematic HuGE review and evidence synthesis
    • DOI 10.1093/aje/kwm167
    • Sanderson, S., Salanti, G. & Higgins, J. Joint effects of the N-acetyltransferase 1 and 2 (NAT1 and NAT2) genes and smoking on bladder carcinogenesis: a literature-based systematic HuGE review and evidence synthesis. Am. J. Epidemiol. 166, 741-751 (2007). (Pubitemid 47428907)
    • (2007) American Journal of Epidemiology , vol.166 , Issue.7 , pp. 741-751
    • Sanderson, S.1    Salanti, G.2    Higgins, J.3
  • 22
    • 77952886405 scopus 로고    scopus 로고
    • A pharmacogenetic study of docetaxel and thalidomide in patients with castration-resistant prostate cancer using the DMET genotyping platform
    • Deeken, J.F. et al. A pharmacogenetic study of docetaxel and thalidomide in patients with castration-resistant prostate cancer using the DMET genotyping platform. Pharmacogenomics J. 10, 191-199 (2010).
    • (2010) Pharmacogenomics J. , vol.10 , pp. 191-199
    • Deeken, J.F.1
  • 23
    • 77955505564 scopus 로고    scopus 로고
    • Biological, clinical and population relevance of 95 loci for blood lipids
    • Teslovich, T.M. et al. Biological, clinical and population relevance of 95 loci for blood lipids. Nature 466, 707-713 (2010).
    • (2010) Nature , vol.466 , pp. 707-713
    • Teslovich, T.M.1
  • 24
    • 77951553451 scopus 로고    scopus 로고
    • Drug-induced liver injury: Past, present and future
    • Daly, A.K. Drug-induced liver injury: past, present and future. Pharmacogenomics 11, 607-611 (2010).
    • (2010) Pharmacogenomics , vol.11 , pp. 607-611
    • Daly, A.K.1
  • 25
    • 70350644759 scopus 로고    scopus 로고
    • A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium
    • Soranzo, N. et al. A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. Nat. Genet. 41, 1182-1190 (2009).
    • (2009) Nat. Genet. , vol.41 , pp. 1182-1190
    • Soranzo, N.1
  • 29
    • 77951766263 scopus 로고    scopus 로고
    • New loci associated with kidney function and chronic kidney disease
    • Köttgen, A. et al. New loci associated with kidney function and chronic kidney disease. Nat. Genet. 42, 376-384 (2010).
    • (2010) Nat. Genet. , vol.42 , pp. 376-384
    • Köttgen, A.1
  • 30
    • 77951768942 scopus 로고    scopus 로고
    • Genetic loci influencing kidney function and chronic kidney disease
    • Chambers, J.C. et al. Genetic loci influencing kidney function and chronic kidney disease. Nat. Genet. 42, 373-375 (2010).
    • (2010) Nat. Genet. , vol.42 , pp. 373-375
    • Chambers, J.C.1
  • 31
    • 15744405825 scopus 로고    scopus 로고
    • Identification of mammalian proline transporter SIT1 (SLC6A20) with characteristics of classical system imino
    • DOI 10.1074/jbc.M413027200
    • Takanaga, H., Mackenzie, B., Suzuki, Y. & Hediger, M.A. Identification of mammalian proline transporter SIT1 (SLC6A20) with characteristics of classical system imino. J. Biol. Chem. 280, 8974-8984 (2005). (Pubitemid 40409589)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.10 , pp. 8974-8984
    • Takanaga, H.1    Mackenzie, B.2    Suzuki, Y.3    Hediger, M.A.4
  • 32
    • 57449088245 scopus 로고    scopus 로고
    • Iminoglycinuria and hyperglycinuria are discrete human phenotypes resulting from complex mutations in proline and glycine transporters
    • Bröer, S. et al. Iminoglycinuria and hyperglycinuria are discrete human phenotypes resulting from complex mutations in proline and glycine transporters. J. Clin. Invest. 118, 3881-3892 (2008).
    • (2008) J. Clin. Invest. , vol.118 , pp. 3881-3892
    • Bröer, S.1
  • 33
    • 79953680469 scopus 로고    scopus 로고
    • Cohort profile: The Study of Health in Pomerania
    • Volzke, H. et al. Cohort profile: the Study of Health in Pomerania. Int. J. Epidemiol. 40, 294-307 (2011).
    • (2011) Int. J. Epidemiol. , vol.40 , pp. 294-307
    • Volzke, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.