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Volumn 7, Issue 5, 2016, Pages 397-413

Limited prolonged effects of rifaximin treatment on irritable bowel syndrome-related differences in the fecal microbiome and metabolome

Author keywords

16s rRNA sequencing; irritable bowel syndrome; metabolomics; metagenomics; rifaximin

Indexed keywords

RIFAXIMIN; RNA 16S; RIFAMYCIN;

EID: 84981710144     PISSN: 19490976     EISSN: 19490984     Source Type: Journal    
DOI: 10.1080/19490976.2016.1215805     Document Type: Article
Times cited : (64)

References (88)
  • 1
    • 59849113547 scopus 로고    scopus 로고
    • Microbes in gastrointestinal health and disease
    • 19026645
    • A.S.Neish. Microbes in gastrointestinal health and disease. Gastroenterology 2009; 136:65-80; PMID:19026645; http://dx.doi.org/10.1053/j.gastro.2008.10.080
    • (2009) Gastroenterology , vol.136 , pp. 65-80
    • Neish, A.S.1
  • 3
    • 84905376185 scopus 로고    scopus 로고
    • Microbiota-host interactions in irritable bowel syndrome: epithelial barrier, immune regulation and brain-gut interactions
    • 25083059
    • N.P.Hyland, E.M.Quigley, E.Brint. Microbiota-host interactions in irritable bowel syndrome:epithelial barrier, immune regulation and brain-gut interactions. World J Gastroenterol 2014; 20:8859-66; PMID:25083059
    • (2014) World J Gastroenterol , vol.20 , pp. 8859-8866
    • Hyland, N.P.1    Quigley, E.M.2    Brint, E.3
  • 5
    • 84924921458 scopus 로고    scopus 로고
    • Efficacy of prebiotics, probiotics, and synbiotics in irritable bowel syndrome and chronic idiopathic constipation: systematic review and meta-analysis
    • A.C.Ford, E.M.Quigley M, B.E.Lacy, A.J.Lembo, Y.A.Saito, L.R.Schiller, E.E.Soffer, B.M.Spiegel, P.Moayyedi. Efficacy of prebiotics, probiotics, and synbiotics in irritable bowel syndrome and chronic idiopathic constipation:systematic review and meta-analysis. Am J Gastroenterol 2014; 109:1547-61, 1562; http://dx.doi.org/10.1038/ajg.2014.202
    • (2014) Am J Gastroenterol , vol.109 , pp. 1562-1561
    • Ford, A.C.1    Quigley, E.M.2    Lacy, B.E.3    Lembo, A.J.4    Saito, Y.A.5    Schiller, L.R.6    Soffer, E.E.7    Spiegel, B.M.8    Moayyedi, P.9
  • 6
    • 33646201266 scopus 로고    scopus 로고
    • The functional gastrointestinal disorders and the Rome III process
    • 16678553
    • D.A.Drossman. The functional gastrointestinal disorders and the Rome III process. Gastroenterology 2006; 130:1377-90; PMID:16678553; http://dx.doi.org/10.1053/j.gastro.2006.03.008
    • (2006) Gastroenterology , vol.130 , pp. 1377-1390
    • Drossman, D.A.1
  • 7
    • 84905389962 scopus 로고    scopus 로고
    • Intestinal microbiota in pathophysiology and management of irritable bowel syndrome
    • 25083061
    • K.N.Lee, O.Y.Lee. Intestinal microbiota in pathophysiology and management of irritable bowel syndrome. World J Gastroenterol 2014; 20:8886-97; PMID:25083061
    • (2014) World J Gastroenterol , vol.20 , pp. 8886-8897
    • Lee, K.N.1    Lee, O.Y.2
  • 8
    • 0036893761 scopus 로고    scopus 로고
    • AGA technical review on irritable bowel syndrome
    • 12454866
    • D.A.Drossman, M.Camilleri, E.A.Mayer, W.E.Whitehead. AGA technical review on irritable bowel syndrome. Gastroenterology 2002; 123:2108-31; PMID:12454866; http://dx.doi.org/10.1053/gast.2002.37095
    • (2002) Gastroenterology , vol.123 , pp. 2108-2131
    • Drossman, D.A.1    Camilleri, M.2    Mayer, E.A.3    Whitehead, W.E.4
  • 9
    • 0023150160 scopus 로고
    • Instability in the faecal flora of a patient suffering from food-related irritable bowel syndrome
    • 3820268
    • H.K.Bradley, G.M.Wyatt, C.E.Bayliss, J.O.Hunter. Instability in the faecal flora of a patient suffering from food-related irritable bowel syndrome. J Med Microbiol 1987; 23:29-32; PMID:3820268; http://dx.doi.org/10.1099/00222615-23-1-29
    • (1987) J Med Microbiol , vol.23 , pp. 29-32
    • Bradley, H.K.1    Wyatt, G.M.2    Bayliss, C.E.3    Hunter, J.O.4
  • 10
    • 3142767014 scopus 로고    scopus 로고
    • Intestinal microecology and quality of life in irritable bowel syndrome patients
    • 15188510
    • J.M.Si, Y.C.Yu, Y.J.Fan, S.J.Chen. Intestinal microecology and quality of life in irritable bowel syndrome patients. World J Gastroenterol 2004; 10:1802-5; PMID:15188510; http://dx.doi.org/10.3748/wjg.v10.i12.1802
    • (2004) World J Gastroenterol , vol.10 , pp. 1802-1805
    • Si, J.M.1    Yu, Y.C.2    Fan, Y.J.3    Chen, S.J.4
  • 11
    • 13944255868 scopus 로고    scopus 로고
    • Analysis of the fecal microbiota of irritable bowel syndrome patients and healthy controls with real-time PCR
    • 15667495
    • E.Malinen, T.Rinttilä, K.Kajander, J.Mättö, A.Kassinen, L.Krogius, M.Saarela, R.Korpela, A.Palva. Analysis of the fecal microbiota of irritable bowel syndrome patients and healthy controls with real-time PCR. Am J Gastroenterol 2005; 100:373-82; PMID:15667495; http://dx.doi.org/10.1111/j.1572-0241.2005.40312.x
    • (2005) Am J Gastroenterol , vol.100 , pp. 373-382
    • Malinen, E.1    Rinttilä, T.2    Kajander, K.3    Mättö, J.4    Kassinen, A.5    Krogius, L.6    Saarela, M.7    Korpela, R.8    Palva, A.9
  • 13
    • 76849116160 scopus 로고    scopus 로고
    • A molecular analysis of fecal and mucosal bacterial communities in irritable bowel syndrome
    • 19693670
    • C.Codling, L.O'Mahony, F.Shanahan, E.M.Quigley, J.R.Marchesi. A molecular analysis of fecal and mucosal bacterial communities in irritable bowel syndrome. Dig Dis Sci 2010; 55:392-7; PMID:19693670; http://dx.doi.org/10.1007/s10620-009-0934-x
    • (2010) Dig Dis Sci , vol.55 , pp. 392-397
    • Codling, C.1    O'Mahony, L.2    Shanahan, F.3    Quigley, E.M.4    Marchesi, J.R.5
  • 14
    • 84905402629 scopus 로고    scopus 로고
    • Methodological issues in the study of intestinal microbiota in irritable bowel syndrome
    • 25083056
    • V.Taverniti, S.Guglielmetti. Methodological issues in the study of intestinal microbiota in irritable bowel syndrome. World J Gastroenterol 2014; 20:8821-36; PMID:25083056
    • (2014) World J Gastroenterol , vol.20 , pp. 8821-8836
    • Taverniti, V.1    Guglielmetti, S.2
  • 15
    • 12844273701 scopus 로고    scopus 로고
    • Composition and temporal stability of gastrointestinal microbiota in irritable bowel syndrome–a longitudinal study in IBS and control subjects
    • J.Mättö, L.Maunuksela, K.Kajander, A.Palva, R.Korpela, A.Kassinen, M.Saarela. Composition and temporal stability of gastrointestinal microbiota in irritable bowel syndrome–a longitudinal study in IBS and control subjects. FEMS Immunol Med Microbiol 2005; 43:213-22; http://dx.doi.org/10.1016/j.femsim.2004.08.009
    • (2005) FEMS Immunol Med Microbiol , vol.43 , pp. 213-222
    • Mättö, J.1    Maunuksela, L.2    Kajander, K.3    Palva, A.4    Korpela, R.5    Kassinen, A.6    Saarela, M.7
  • 17
    • 33646359935 scopus 로고    scopus 로고
    • Small intestine bacterial overgrowth in irritable bowel syndrome: a retrospective study with rifaximin
    • 16554709
    • L.Cuoco, M.Salvagnini. Small intestine bacterial overgrowth in irritable bowel syndrome:a retrospective study with rifaximin. Minerva Gastroenterol Dietol 2006; 52:89-95; PMID:16554709
    • (2006) Minerva Gastroenterol Dietol , vol.52 , pp. 89-95
    • Cuoco, L.1    Salvagnini, M.2
  • 18
    • 67651222067 scopus 로고    scopus 로고
    • Small intestine bacterial overgrowth and irritable bowel syndrome-related symptoms: experience with Rifaximin
    • 19496193
    • S.Peralta, C.Cottone, T.Doveri, P.L.Almasio, A.Craxi. Small intestine bacterial overgrowth and irritable bowel syndrome-related symptoms:experience with Rifaximin. World J Gastroenterol 2009; 15:2628-31; PMID:19496193; http://dx.doi.org/10.3748/wjg.15.2628
    • (2009) World J Gastroenterol , vol.15 , pp. 2628-2631
    • Peralta, S.1    Cottone, C.2    Doveri, T.3    Almasio, P.L.4    Craxi, A.5
  • 19
    • 37249035165 scopus 로고    scopus 로고
    • Rifaximin vs. other antibiotics in the primary treatment and retreatment of bacterial overgrowth in IBS
    • 17520365
    • J.Yang, H.R.Lee, K.Low, S.Chatterjee, M.Pimentel. Rifaximin vs. other antibiotics in the primary treatment and retreatment of bacterial overgrowth in IBS. Dig Dis Sci 2008; 53:169-74; PMID:17520365; http://dx.doi.org/10.1007/s10620-007-9839-8
    • (2008) Dig Dis Sci , vol.53 , pp. 169-174
    • Yang, J.1    Lee, H.R.2    Low, K.3    Chatterjee, S.4    Pimentel, M.5
  • 25
    • 84855462831 scopus 로고    scopus 로고
    • The efficacy and safety of rifaximin for the irritable bowel syndrome: a systematic review and meta-analysis
    • quiz 36, 22045120
    • S.B.Menees, M.Maneerattannaporn, H.M.Kim, W.D.Chey. The efficacy and safety of rifaximin for the irritable bowel syndrome:a systematic review and meta-analysis. Am J Gastroenterol 2012; 107:28-35; quiz 36; PMID:22045120; http://dx.doi.org/10.1038/ajg.2011.355
    • (2012) Am J Gastroenterol , vol.107 , pp. 28-35
    • Menees, S.B.1    Maneerattannaporn, M.2    Kim, H.M.3    Chey, W.D.4
  • 26
    • 0033854244 scopus 로고    scopus 로고
    • Non-absorbable antibiotics for managing intestinal gas production and gas-related symptoms
    • 10930893
    • M.Di Stefano, A.Strocchi, S.Malservisi, G.Veneto, A.Ferrieri, G.R.Corazza. Non-absorbable antibiotics for managing intestinal gas production and gas-related symptoms. Aliment Pharmacol Ther 2000; 14:1001-8; PMID:10930893; http://dx.doi.org/10.1046/j.1365-2036.2000.00808.x
    • (2000) Aliment Pharmacol Ther , vol.14 , pp. 1001-1008
    • Di Stefano, M.1    Strocchi, A.2    Malservisi, S.3    Veneto, G.4    Ferrieri, A.5    Corazza, G.R.6
  • 27
    • 77949346102 scopus 로고    scopus 로고
    • The place of antibiotics in management of irritable bowel syndrome: a systematic review and meta-analysis
    • 22371720
    • A.Rezaie, S.Nikfar, M.Abdollahi. The place of antibiotics in management of irritable bowel syndrome:a systematic review and meta-analysis. Arch Med Sci 2010; 6:49-55; PMID:22371720; http://dx.doi.org/10.5114/aoms.2010.13507
    • (2010) Arch Med Sci , vol.6 , pp. 49-55
    • Rezaie, A.1    Nikfar, S.2    Abdollahi, M.3
  • 28
    • 84952915656 scopus 로고    scopus 로고
    • Review article: potential mechanisms of action of rifaximin in the management of irritable bowel syndrome with diarrhoea
    • 26618924
    • M.Pimentel. Review article:potential mechanisms of action of rifaximin in the management of irritable bowel syndrome with diarrhoea. Aliment Pharmacol Ther 2016; 43 Suppl 1:37-49; PMID:26618924; http://dx.doi.org/10.1111/apt.13437
    • (2016) Aliment Pharmacol Ther , vol.43 , Issue.1 , pp. 37-49
    • Pimentel, M.1
  • 29
    • 84936937057 scopus 로고    scopus 로고
    • Profile of rifaximin and its potential in the treatment of irritable bowel syndrome
    • 26089696
    • N.Iorio, Z.Malik, R.Schey. Profile of rifaximin and its potential in the treatment of irritable bowel syndrome. Clin Exp Gastroenterol 2015; 8:159-67; PMID:26089696
    • (2015) Clin Exp Gastroenterol , vol.8 , pp. 159-167
    • Iorio, N.1    Malik, Z.2    Schey, R.3
  • 30
    • 84875497594 scopus 로고    scopus 로고
    • Rifaximin treatment for the irritable bowel syndrome with a positive lactulose hydrogen breath test improves symptoms for at least 3 months
    • 23066911
    • P.Meyrat, E.Safroneeva, A.M.Schoepfer. Rifaximin treatment for the irritable bowel syndrome with a positive lactulose hydrogen breath test improves symptoms for at least 3 months. Aliment Pharmacol Ther 2012; 36:1084-93; PMID:23066911; http://dx.doi.org/10.1111/apt.12087
    • (2012) Aliment Pharmacol Ther , vol.36 , pp. 1084-1093
    • Meyrat, P.1    Safroneeva, E.2    Schoepfer, A.M.3
  • 31
    • 33750721328 scopus 로고    scopus 로고
    • The effect of a nonabsorbed oral antibiotic (rifaximin) on the symptoms of the irritable bowel syndrome: a randomized trial
    • 17043337
    • M.Pimentel, S.Park, J.Mirocha, S.V.Kane, Y.Kong. The effect of a nonabsorbed oral antibiotic (rifaximin) on the symptoms of the irritable bowel syndrome:a randomized trial. Ann Intern Med 2006; 145:557-63; PMID:17043337; http://dx.doi.org/10.7326/0003-4819-145-8-200610170-00004
    • (2006) Ann Intern Med , vol.145 , pp. 557-563
    • Pimentel, M.1    Park, S.2    Mirocha, J.3    Kane, S.V.4    Kong, Y.5
  • 32
    • 33644912601 scopus 로고    scopus 로고
    • A randomized double-blind placebo-controlled trial of rifaximin in patients with abdominal bloating and flatulence
    • 16454838
    • A.I.Sharara, E.Aoun, H.Abdul-Baki, R.Mounzer, S.Sidani, I.Elhajj. A randomized double-blind placebo-controlled trial of rifaximin in patients with abdominal bloating and flatulence. Am J Gastroenterol 2006; 101:326-33; PMID:16454838; http://dx.doi.org/10.1111/j.1572-0241.2006.00458.x
    • (2006) Am J Gastroenterol , vol.101 , pp. 326-333
    • Sharara, A.I.1    Aoun, E.2    Abdul-Baki, H.3    Mounzer, R.4    Sidani, S.5    Elhajj, I.6
  • 33
    • 84861578319 scopus 로고    scopus 로고
    • An irritable bowel syndrome subtype defined by species-specific alterations in faecal microbiota
    • 22180058
    • I.B.Jeffery, P.W.O'Toole, L.Öhman, M.J.Claesson, J.Deane, E.M.Quigley, M.Simrén. An irritable bowel syndrome subtype defined by species-specific alterations in faecal microbiota. Gut 2012; 61:997-1006; PMID:22180058; http://dx.doi.org/10.1136/gutjnl-2011-301501
    • (2012) Gut , vol.61 , pp. 997-1006
    • Jeffery, I.B.1    O'Toole, P.W.2    Öhman, L.3    Claesson, M.J.4    Deane, J.5    Quigley, E.M.6    Simrén, M.7
  • 34
    • 84949490326 scopus 로고    scopus 로고
    • Modulation of the gut microbiota composition by rifaximin in non-constipated irritable bowel syndrome patients: a molecular approach
    • 26673000
    • S.Soldi, S.Vasileiadis, F.Uggeri, M.Campanale, L.Morelli, M.V.Fogli, F.Calanni, M.Grimaldi, A.Gasbarrini. Modulation of the gut microbiota composition by rifaximin in non-constipated irritable bowel syndrome patients:a molecular approach. Clin Exp Gastroenterol 2015; 8:309-25; PMID:26673000; http://dx.doi.org/10.2147/CEG.S89999
    • (2015) Clin Exp Gastroenterol , vol.8 , pp. 309-325
    • Soldi, S.1    Vasileiadis, S.2    Uggeri, F.3    Campanale, M.4    Morelli, L.5    Fogli, M.V.6    Calanni, F.7    Grimaldi, M.8    Gasbarrini, A.9
  • 35
    • 84908293797 scopus 로고    scopus 로고
    • Irritable bowel syndrome: a clinical review
    • 25232249
    • R.L.Soares. Irritable bowel syndrome:a clinical review. World J Gastroenterol 2014; 20:12144-60; PMID:25232249; http://dx.doi.org/10.3748/wjg.v20.i34.12144
    • (2014) World J Gastroenterol , vol.20 , pp. 12144-12160
    • Soares, R.L.1
  • 36
    • 84905365322 scopus 로고    scopus 로고
    • Irritable bowel syndrome: a disease still searching for pathogenesis, diagnosis and therapy
    • 25083055
    • M.Bellini, D.Gambaccini, C.Stasi, M.T.Urbano, S.Marchi, P.Usai-Satta. Irritable bowel syndrome:a disease still searching for pathogenesis, diagnosis and therapy. World J Gastroenterol 2014; 20:8807-20; PMID:25083055
    • (2014) World J Gastroenterol , vol.20 , pp. 8807-8820
    • Bellini, M.1    Gambaccini, D.2    Stasi, C.3    Urbano, M.T.4    Marchi, S.5    Usai-Satta, P.6
  • 37
    • 84892825869 scopus 로고    scopus 로고
    • Rifaximin alters intestinal bacteria and prevents stress-induced gut inflammation and visceral hyperalgesia in rats
    • 24161699
    • D.Xu, J.Gao, M.Gillilland, X.Wu, I.Song, J.Y.Kao, C.Owyang. Rifaximin alters intestinal bacteria and prevents stress-induced gut inflammation and visceral hyperalgesia in rats. Gastroenterol 2014; 146:484-496. e4; PMID:24161699; http://dx.doi.org/10.1053/j.gastro.2013.10.026
    • (2014) Gastroenterol , vol.146 , pp. e4-e496
    • Xu, D.1    Gao, J.2    Gillilland, M.3    Wu, X.4    Song, I.5    Kao, J.Y.6    Owyang, C.7
  • 38
    • 80052481927 scopus 로고    scopus 로고
    • Metabolomics of fecal extracts detects altered metabolic activity of gut microbiota in ulcerative colitis and irritable bowel syndrome
    • 21761941
    • G.Le Gall, S.O.Noor, K.Ridgway, L.Scovell, C.Jamieson, I.T.Johnson, I.J.Colquhoun, E.K.Kemsley, A.Narbad. Metabolomics of fecal extracts detects altered metabolic activity of gut microbiota in ulcerative colitis and irritable bowel syndrome. J Proteome Res 2011; 10:4208-18; PMID:21761941; http://dx.doi.org/10.1021/pr2003598
    • (2011) J Proteome Res , vol.10 , pp. 4208-4218
    • Le Gall, G.1    Noor, S.O.2    Ridgway, K.3    Scovell, L.4    Jamieson, C.5    Johnson, I.T.6    Colquhoun, I.J.7    Kemsley, E.K.8    Narbad, A.9
  • 39
    • 22844432598 scopus 로고    scopus 로고
    • The influence of microbial metabolites on human intestinal epithelial cells and macrophages in vitro
    • 15939578
    • M.H.van Nuenen, R.A.de Ligt, R.P.Doornbos, J.C.van der Woude, E.J.Kuipers, K.Venema. The influence of microbial metabolites on human intestinal epithelial cells and macrophages in vitro. FEMS Immunol Med Microbiol 2005; 45:183-9; PMID:15939578; http://dx.doi.org/10.1016/j.femsim.2005.03.010
    • (2005) FEMS Immunol Med Microbiol , vol.45 , pp. 183-189
    • van Nuenen, M.H.1    de Ligt, R.A.2    Doornbos, R.P.3    van der Woude, J.C.4    Kuipers, E.J.5    Venema, K.6
  • 40
    • 84902247158 scopus 로고    scopus 로고
    • Metabolomics as a diagnostic tool in gastroenterology
    • 24199025
    • V.De Preter, K.Verbeke. Metabolomics as a diagnostic tool in gastroenterology. World J Gastrointest Pharmacol Ther 2013; 4:97-107; PMID:24199025
    • (2013) World J Gastrointest Pharmacol Ther , vol.4 , pp. 97-107
    • De Preter, V.1    Verbeke, K.2
  • 42
    • 84874828665 scopus 로고    scopus 로고
    • An investigation of fecal volatile organic metabolites in irritable bowel syndrome
    • I.Ahmed, R.Greenwood, L.Costello Bde, N.M.Ratcliffe, C.S.Probert. An investigation of fecal volatile organic metabolites in irritable bowel syndrome. PLoS One 2013; 8:e58204.
    • (2013) PLoS One , vol.8 , pp. e58204
    • Ahmed, I.1    Greenwood, R.2    Costello Bde, L.3    Ratcliffe, N.M.4    Probert, C.S.5
  • 43
    • 79957601426 scopus 로고    scopus 로고
    • Microbial community and metabolomic comparison of irritable bowel syndrome faeces
    • 21330412
    • K.Ponnusamy, J.N.Choi, J.Kim, S.Y.Lee, C.H.Lee. Microbial community and metabolomic comparison of irritable bowel syndrome faeces. J Med Microbiol 2011; 60:817-27; PMID:21330412; http://dx.doi.org/10.1099/jmm.0.028126-0
    • (2011) J Med Microbiol , vol.60 , pp. 817-827
    • Ponnusamy, K.1    Choi, J.N.2    Kim, J.3    Lee, S.Y.4    Lee, C.H.5
  • 47
    • 84871709986 scopus 로고    scopus 로고
    • Biodiversity and functional genomics in the human microbiome
    • 23140990
    • X.C.Morgan, N.Segata, C.Huttenhower. Biodiversity and functional genomics in the human microbiome. Trends Genet 2013; 29:51-8; PMID:23140990; http://dx.doi.org/10.1016/j.tig.2012.09.005
    • (2013) Trends Genet , vol.29 , pp. 51-58
    • Morgan, X.C.1    Segata, N.2    Huttenhower, C.3
  • 49
    • 84893707135 scopus 로고    scopus 로고
    • Intestinal microbiota, diet and health
    • 23931069
    • S.E.Power, P.W.O'Toole, C.Stanton, R.P.Ross, G.F.Fitzgerald. Intestinal microbiota, diet and health. Br J Nutr 2014; 111:387-402; PMID:23931069; http://dx.doi.org/10.1017/S0007114513002560
    • (2014) Br J Nutr , vol.111 , pp. 387-402
    • Power, S.E.1    O'Toole, P.W.2    Stanton, C.3    Ross, R.P.4    Fitzgerald, G.F.5
  • 50
    • 84920489030 scopus 로고    scopus 로고
    • Healthy control subjects are poorly defined in case-control studies of irritable bowel syndrome
    • 25609236
    • S.Ghorbani, A.Nejad, D.Law, K.S.Chua, M.M.Amichai, M.Pimentel. Healthy control subjects are poorly defined in case-control studies of irritable bowel syndrome. Ann Gastroenterol 2015; 28:87-93; PMID:25609236
    • (2015) Ann Gastroenterol , vol.28 , pp. 87-93
    • Ghorbani, S.1    Nejad, A.2    Law, D.3    Chua, K.S.4    Amichai, M.M.5    Pimentel, M.6
  • 52
    • 84989245447 scopus 로고    scopus 로고
    • 16S rRNA gene-based profiling of the human infant gut microbiota is strongly influenced by sample processing and PCR primer choice
    • 26120470
    • A.W.Walker, J.C.Martin, P.Scott, J.Parkhill, H.J.Flint, K.P.Scott. 16S rRNA gene-based profiling of the human infant gut microbiota is strongly influenced by sample processing and PCR primer choice. Microbiome 2015; 3:26; PMID:26120470; http://dx.doi.org/10.1186/s40168-015-0087-4
    • (2015) Microbiome , vol.3 , pp. 26
    • Walker, A.W.1    Martin, J.C.2    Scott, P.3    Parkhill, J.4    Flint, H.J.5    Scott, K.P.6
  • 53
    • 34547683600 scopus 로고    scopus 로고
    • Diversity of the human gastrointestinal tract microbiota revisited
    • 17686012
    • M.Rajilić-Stojanović, H.Smidt, W.M.de Vos. Diversity of the human gastrointestinal tract microbiota revisited. Environ Microbiol 2007; 9:2125-36; PMID:17686012; http://dx.doi.org/10.1111/j.1462-2920.2007.01369.x
    • (2007) Environ Microbiol , vol.9 , pp. 2125-2136
    • Rajilić-Stojanović, M.1    Smidt, H.2    de Vos, W.M.3
  • 54
    • 74549185684 scopus 로고    scopus 로고
    • Microbial community analysis reveals high level phylogenetic alterations in the overall gastrointestinal microbiota of diarrhoea-predominant irritable bowel syndrome sufferers
    • 20015409
    • L.Krogius-Kurikka, A.Lyra, E.Malinen, J.Aarnikunnas, J.Tuimala, L.Paulin, H.Mäkivuokko, K.Kajander, A.Palva. Microbial community analysis reveals high level phylogenetic alterations in the overall gastrointestinal microbiota of diarrhoea-predominant irritable bowel syndrome sufferers. BMC Gastroenterol 2009; 9:95; PMID:20015409; http://dx.doi.org/10.1186/1471-230X-9-95
    • (2009) BMC Gastroenterol , vol.9 , pp. 95
    • Krogius-Kurikka, L.1    Lyra, A.2    Malinen, E.3    Aarnikunnas, J.4    Tuimala, J.5    Paulin, L.6    Mäkivuokko, H.7    Kajander, K.8    Palva, A.9
  • 55
    • 84861185968 scopus 로고    scopus 로고
    • Alterations in composition and diversity of the intestinal microbiota in patients with diarrhea-predominant irritable bowel syndrome
    • 22339879
    • I.M.Carroll, T.Ringel-Kulka, J.P.Siddle, Y.Ringel. Alterations in composition and diversity of the intestinal microbiota in patients with diarrhea-predominant irritable bowel syndrome. Neurogastroenterol Motil 2012; 24:521-30, e248; PMID:22339879; http://dx.doi.org/10.1111/j.1365-2982.2012.01891.x
    • (2012) Neurogastroenterol Motil , vol.24 , pp. e248-e230
    • Carroll, I.M.1    Ringel-Kulka, T.2    Siddle, J.P.3    Ringel, Y.4
  • 56
    • 69549086278 scopus 로고    scopus 로고
    • The effects of ageing on the colonic bacterial microflora in adults
    • 19606407
    • P.Enck, K.Zimmermann, K.Rusch, A.Schwiertz, S.Klosterhalfen, J.-S.Frick. The effects of ageing on the colonic bacterial microflora in adults. Z Gastroenterol 2009; 47:653-8; PMID:19606407; http://dx.doi.org/10.1055/s-0028-1109055
    • (2009) Z Gastroenterol , vol.47 , pp. 653-658
    • Enck, P.1    Zimmermann, K.2    Rusch, K.3    Schwiertz, A.4    Klosterhalfen, S.5    Frick, J.-S.6
  • 58
    • 80051785670 scopus 로고    scopus 로고
    • Luminal and mucosal-associated intestinal microbiota in patients with diarrhea-predominant irritable bowel syndrome
    • 21143915
    • I.M.Carroll, Y.H.Chang, J.Park, R.B.Sartor, Y.Ringel. Luminal and mucosal-associated intestinal microbiota in patients with diarrhea-predominant irritable bowel syndrome. Gut Pathog 2010; 2:19; PMID:21143915; http://dx.doi.org/10.1186/1757-4749-2-19
    • (2010) Gut Pathog , vol.2 , pp. 19
    • Carroll, I.M.1    Chang, Y.H.2    Park, J.3    Sartor, R.B.4    Ringel, Y.5
  • 59
    • 84867863334 scopus 로고    scopus 로고
    • Dysbiosis in ukrainian children with irritable bowel syndrome affected by natural radiation
    • 23400266
    • M.R.Sheikh Sajjadieh, L.V.Kuznetsova, V.B.Bojenko. Dysbiosis in ukrainian children with irritable bowel syndrome affected by natural radiation. Iran J Pediatr 2012; 22:364-8; PMID:23400266
    • (2012) Iran J Pediatr , vol.22 , pp. 364-368
    • Sheikh Sajjadieh, M.R.1    Kuznetsova, L.V.2    Bojenko, V.B.3
  • 60
    • 77950670562 scopus 로고    scopus 로고
    • Altered profiles of intestinal microbiota and organic acids may be the origin of symptoms in irritable bowel syndrome
    • 19903265
    • C.Tana, Y.Umesaki, A.Imaoka, T.Handa, M.Kanazawa, S.Fukudo. Altered profiles of intestinal microbiota and organic acids may be the origin of symptoms in irritable bowel syndrome. Neurogastroenterol Motil 2010; 22:512-9, e114-115; PMID:19903265
    • (2010) Neurogastroenterol Motil , vol.22 , pp. e114-e115
    • Tana, C.1    Umesaki, Y.2    Imaoka, A.3    Handa, T.4    Kanazawa, M.5    Fukudo, S.6
  • 62
    • 79251495453 scopus 로고    scopus 로고
    • Molecular analysis of faecal and duodenal samples reveals significantly higher prevalence and numbers of Pseudomonas aeruginosa in irritable bowel syndrome
    • 20947663
    • A.P.Kerckhoffs, K.Ben-Amor, M.Samsom, M.E.van der Rest, J.de Vogel, J.Knol, L.M.Akkermans. Molecular analysis of faecal and duodenal samples reveals significantly higher prevalence and numbers of Pseudomonas aeruginosa in irritable bowel syndrome. J Med Microbiol 2011; 60:236-45; PMID:20947663; http://dx.doi.org/10.1099/jmm.0.022848-0
    • (2011) J Med Microbiol , vol.60 , pp. 236-245
    • Kerckhoffs, A.P.1    Ben-Amor, K.2    Samsom, M.3    van der Rest, M.E.4    de Vogel, J.5    Knol, J.6    Akkermans, L.M.7
  • 64
    • 84869493735 scopus 로고    scopus 로고
    • Quantitative profiling of gut microbiota of children with diarrhea-predominant irritable bowel syndrome
    • 22986438
    • L.Rigsbee, R.Agans, V.Shankar, H.Kenche, H.J.Khamis, S.Michail, O.Paliy. Quantitative profiling of gut microbiota of children with diarrhea-predominant irritable bowel syndrome. Am J Gastroenterol 2012; 107:1740-51; PMID:22986438; http://dx.doi.org/10.1038/ajg.2012.287
    • (2012) Am J Gastroenterol , vol.107 , pp. 1740-1751
    • Rigsbee, L.1    Agans, R.2    Shankar, V.3    Kenche, H.4    Khamis, H.J.5    Michail, S.6    Paliy, O.7
  • 66
    • 65449165950 scopus 로고    scopus 로고
    • Postinfectious irritable bowel syndrome
    • 19457422
    • R.Spiller, K.Garsed. Postinfectious irritable bowel syndrome. Gastroenterology 2009; 136:1979-88; PMID:19457422; http://dx.doi.org/10.1053/j.gastro.2009.02.074
    • (2009) Gastroenterology , vol.136 , pp. 1979-1988
    • Spiller, R.1    Garsed, K.2
  • 69
    • 84899114664 scopus 로고    scopus 로고
    • Safety and tolerability of rifaximin for the treatment of irritable bowel syndrome without constipation: a pooled analysis of randomised, double-blind, placebo-controlled trials
    • 24697851
    • P.Schoenfeld, M.Pimentel, L.Chang, A.Lembo, W.D.Chey, J.Yu, C.Paterson, E.Bortey, W.P.Forbes. Safety and tolerability of rifaximin for the treatment of irritable bowel syndrome without constipation:a pooled analysis of randomised, double-blind, placebo-controlled trials. Aliment Pharmacol Ther 2014; 39:1161-8; PMID:24697851; http://dx.doi.org/10.1111/apt.12735
    • (2014) Aliment Pharmacol Ther , vol.39 , pp. 1161-1168
    • Schoenfeld, P.1    Pimentel, M.2    Chang, L.3    Lembo, A.4    Chey, W.D.5    Yu, J.6    Paterson, C.7    Bortey, E.8    Forbes, W.P.9
  • 70
    • 84875513134 scopus 로고    scopus 로고
    • Rifaximin in irritable bowel syndrome: rationale, evidence and clinical use
    • 23556126
    • M.Saadi, R.W.McCallum. Rifaximin in irritable bowel syndrome:rationale, evidence and clinical use. Ther Adv Chronic Dis 2013; 4:71-5; PMID:23556126; http://dx.doi.org/10.1177/2040622312472008
    • (2013) Ther Adv Chronic Dis , vol.4 , pp. 71-75
    • Saadi, M.1    McCallum, R.W.2
  • 72
    • 34248573696 scopus 로고    scopus 로고
    • Review article: the role of antibiotics vs. conventional pharmacotherapy in treating symptoms of irritable bowel syndrome
    • 17509095
    • C.L.Frissora, B.D.Cash. Review article:the role of antibiotics vs. conventional pharmacotherapy in treating symptoms of irritable bowel syndrome. Aliment Pharmacol Ther 2007; 25:1271-81; PMID:17509095; http://dx.doi.org/10.1111/j.1365-2036.2007.03313.x
    • (2007) Aliment Pharmacol Ther , vol.25 , pp. 1271-1281
    • Frissora, C.L.1    Cash, B.D.2
  • 75
    • 64949194229 scopus 로고    scopus 로고
    • Metabolite profiling of fecal water extracts from human colorectal cancer
    • D.Monleón, J.M.Morales, A.Barrasa, J.A.López, C.Vázquez, B.Celda. Metabolite profiling of fecal water extracts from human colorectal cancer. NMR Biomed 2009; 22:342-8; http://dx.doi.org/10.1002/nbm.1345
    • (2009) NMR Biomed , vol.22 , pp. 342-348
    • Monleón, D.1    Morales, J.M.2    Barrasa, A.3    López, J.A.4    Vázquez, C.5    Celda, B.6
  • 76
    • 37149033981 scopus 로고    scopus 로고
    • Systematic review and meta-analysis: the clinical and physiological effects of fibre-containing enteral formulae
    • 17922802
    • M.Elia, M.B.Engfer, C.J.Green, D.B.Silk. Systematic review and meta-analysis:the clinical and physiological effects of fibre-containing enteral formulae. Aliment Pharmacol Ther 2008; 27:120-45; PMID:17922802; http://dx.doi.org/10.1111/j.1365-2036.2007.03544.x
    • (2008) Aliment Pharmacol Ther , vol.27 , pp. 120-145
    • Elia, M.1    Engfer, M.B.2    Green, C.J.3    Silk, D.B.4
  • 77
    • 0030731874 scopus 로고    scopus 로고
    • Absence of gaseous symptoms during ingestion of commercial fibre preparations
    • 9663831
    • L.Zumarraga, M.D.Levitt, F.Suarez. Absence of gaseous symptoms during ingestion of commercial fibre preparations. Aliment Pharmacol Ther 1997; 11:1067-72; PMID:9663831; http://dx.doi.org/10.1046/j.1365-2036.1997.00250.x
    • (1997) Aliment Pharmacol Ther , vol.11 , pp. 1067-1072
    • Zumarraga, L.1    Levitt, M.D.2    Suarez, F.3
  • 78
    • 84923335326 scopus 로고    scopus 로고
    • No difference in small bowel microbiota between patients with irritable bowel syndrome and healthy controls
    • 25687743
    • A.Dlugosz, B.Winckler, E.Lundin, K.Zakikhany, G.Sandström, W.Ye, L.Engstrand, G.Lindberg. No difference in small bowel microbiota between patients with irritable bowel syndrome and healthy controls. Sci Rep 2015; 5:8508; PMID:25687743; http://dx.doi.org/10.1038/srep08508
    • (2015) Sci Rep , vol.5 , pp. 8508
    • Dlugosz, A.1    Winckler, B.2    Lundin, E.3    Zakikhany, K.4    Sandström, G.5    Ye, W.6    Engstrand, L.7    Lindberg, G.8
  • 81
    • 84988520486 scopus 로고    scopus 로고
    • [cited 2015 Apr 6]
    • FASTX-Toolkit [Internet]. [cited 2015 Apr 6]; Available from:http://hannonlab.cshl.edu/fastx_toolkit/index.html
  • 82
    • 84911429654 scopus 로고    scopus 로고
    • STAMP: statistical analysis of taxonomic and functional profiles
    • 25061070
    • D.H.Parks, G.W.Tyson, P.Hugenholtz, R.G.Beiko. STAMP:statistical analysis of taxonomic and functional profiles. Bioinformatics 2014; 30:3123-4; PMID:25061070; http://dx.doi.org/10.1093/bioinformatics/btu494
    • (2014) Bioinformatics , vol.30 , pp. 3123-3124
    • Parks, D.H.1    Tyson, G.W.2    Hugenholtz, P.3    Beiko, R.G.4
  • 83
    • 84988477470 scopus 로고    scopus 로고
    • ggplot2: Elegant Graphics for Data Analysis
    • 1st, New York: Springer
    • H.Wickham. ggplot2:Elegant Graphics for Data Analysis. 1st ed. 2009. Corr. 3rd printing 2010 edition. New York:Springer; 2010
    • (2010) Corr. 3rd printing 2010 edition
    • Wickham, H.1
  • 84
    • 84988471199 scopus 로고
    • Controlling the false discovery rate: A practical and powerful approach to multiple testing
    • Y.Benjamini, Y.Hochberg. Controlling the false discovery rate:A practical and powerful approach to multiple testing. J Royal Statistical Society Series B (Methodological) 1995; 57:289-300.
    • (1995) J Royal Statistical Society Series B (Methodological) , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 85
    • 34547145165 scopus 로고    scopus 로고
    • G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences
    • 17695343
    • F.Faul, E.Erdfelder, A.-G.Lang, A.Buchner. G*Power 3:a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods 2007; 39:175-91; PMID:17695343; http://dx.doi.org/10.3758/BF03193146
    • (2007) Behav Res Methods , vol.39 , pp. 175-191
    • Faul, F.1    Erdfelder, E.2    Lang, A.-G.3    Buchner, A.4
  • 88
    • 84894887900 scopus 로고
    • Computer Aided Design of Experiments
    • R.W.Kennard, L.A.Stone. Computer Aided Design of Experiments. Technometrics 1969; 11:137-48; http://dx.doi.org/10.1080/00401706.1969.10490666
    • (1969) Technometrics , vol.11 , pp. 137-148
    • Kennard, R.W.1    Stone, L.A.2


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