The effects of ageing on the colonic bacterial microflora in adults

Zeitschrift fur Gastroenterologie

Volumn 47, Issue 7, 2009, Pages 653-658

  Enck, P ^a   Zimmermann, K ^b   Rusch, K ^b   Schwiertz, A ^b   Klosterhalfen, S ^a,c   Frick, J S ^a  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^b Symbio Herborn Group GmbH   (Germany)

^c Institute for Clinical Neurosciences and Medical Psychology   (Germany)

Author keywords

Ageing; Colon; Commensal bacteria

Indexed keywords

ADULT; AGED; AGING; ARTICLE; BACTERIUM COLONY; BACTEROIDES; BIFIDOBACTERIUM; CLOSTRIDIUM DIFFICILE; COLON FLORA; COLONY FORMING UNIT; CROHN DISEASE; ENTEROCOCCUS; ESCHERICHIA COLI; FECES ANALYSIS; FECES MICROFLORA; FEMALE; GASTROINTESTINAL DISEASE; HUMAN; IRRITABLE COLON; LACTOBACILLUS; MAJOR CLINICAL STUDY; MALE; ULCERATIVE COLITIS;

ADULT; AGE DISTRIBUTION; AGED; AGED, 80 AND OVER; AGING; COLITIS; COLON; FECES; FEMALE; GERMANY; HUMANS; MALE; MIDDLE AGED; PREVALENCE; YOUNG ADULT;

EID: 69549086278     PISSN: 00442771     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0028-1109055     Document Type: Article

References (37)

1. Gueimonde M, Ouwehand A, Huhtinen H et al. Qualitative and quantitative analyses of the bifidobacterial microbiota in the colonic mucosa of patients with colorectal cancer, diverticulitis and inflammatory bowel disease. World J Gastroenterol 2007; 13: 3985-3989 (Pubitemid 47272497)
2. Mylonaki M, Rayment NB, Rampton DS et al. Molecular characterization of rectal mucosa-associated bacterial flora in inflammatory bowel disease. Inflamm Bowel Dis 2005; 11: 481-487 (Pubitemid 40704083)
3. Moore WE, Moore LH. Intestinal floras of populations that have a high risk of colon cancer. Appl Environ Microbiol 1995; 61: 3202-3207
4. Benno Y, Endo K, Mizutani T et al. Comparison of fecal microflora of elderly persons in rural and urban areas of Japan. Appl Environ Microbiol 1989; 55: 1100-1105 (Pubitemid 19120705)
5. Hayashi H, Sakamoto M, Benno Y. Fecal microbial diversity in a strict vegetarian as determined by molecular analysis and cultivation. Microbiol Immunol 2002; 46: 819-831 (Pubitemid 36019156)
6. Finegold SM, Attebery HR, Sutter VL. Effect of diet on human fecal flora: comparison of Japanese and American diets. Am J Clin Nutr 1974; 27: 1456-1469
7. Mueller S, Saunier K, Hanisch C et al. Differences in fecal microbiota in different European study populations in relation to age, gender, and country: a cross-sectional study. Appl Environ Microbiol 2006; 72: 1027-1033 (Pubitemid 43271206)
8. Ferguson LR, Shelling AN, Browning BL et al. Genes, diet and inflammatory bowel disease. Mutat Res 2007; 622: 70-83
9. Milner JA. Nutrition and cancer: Essential elements for a roadmap. Cancer Lett 2008; 269: 189-198
10. Bruzzese E, Canani RB, De Marco G et al. Microflora in inflammatory bowel diseases: a pediatric perspective. J Clin Gastroenterol 2004; 38: S91-S93
11. Hudson MJ, Hill MJ, Elliott PR et al. The microbial flora of the rectal mucosa and faeces of patients with Crohn's disease before and during antimicrobial chemotherapy. J Med Microbiol 1984; 18: 335-345
12. McFarland LV, Dublin S. Meta-analysis of probiotics for the treatment of irritable bowel syndrome. World J Gastroenterol 2008; 14: 2650-2661
13. Nikfar S, Rahimi R, Rahimi F et al. Efficacy of probiotics in irritable bowel syndrome: a meta-analysis of randomized, controlled trials. Dis Colon Rectum 2008; 51: 1775-1780
14. Rembacken BJ, Snelling AM, Hawkey PM et al. Non-pathogenic Escherichia coli versus mesalazine for the treatment of ulcerative colitis: a randomised trial. Lancet 1999; 354: 635-639
15. Lievin-Le MV, Sarrazin-Davila LE, Servin AL. An experimental study and a randomized, double-blind, placebo-controlled clinical trial to evaluate the antisecretory activity of Lactobacillus acidophilus strain LB against nonrotavirus diarrhea. Pediatrics 2007; 120: e795-e803
16. Gionchetti P, Rizzello F, Venturi A et al. Probiotics in infective diarrhoea and inflammatory bowel diseases. J Gastroenterol Hepatol 2000; 15: 489-493 (Pubitemid 30327049)
17. Gionchetti P, Rizzello F, Venturi A et al. Oral bacteriotherapy as maintenance treatment in patients with chronic pouchitis: a double-blind, placebo-controlled trial. Gastroenterology 2000; 119: 305-309 (Pubitemid 30621980)
18. Gill HS. Probiotics to enhance anti-infective defences in the gastrointestinal tract. Best Pract Res Clin Gastroenterol 2003; 17: 755-773 (Pubitemid 37554721)
19. Cong Y, Konrad A, Iqbal N et al. Probiotics and immune regulation of inflammatory bowel diseases. Curr Drug Targets lnflamm Allergy 2003; 2: 145-154
20. Arslanoglu S, Moro GE, Schmitt J et al. Early dietary intervention with a mixture of prebiotic oligosaccharides reduces the incidence of allergic manifestations and infections during the first two years of life. J Nutr 2008; 138: 1091-1095 (Pubitemid 351769134)
21. Huurre A, Laitinen K, Rautava S et al. Impact of maternal atopy and probiotic supplementation during pregnancy on infant sensitization: a double-blind placebo-controlled study. Clin Exp Allergy 2008; 38: 1342-1348 (Pubitemid 352019662)
22. Zuccotti GV, Meneghin F, Raimondi C et al. Probiotics in clinical practice: an overview. J Int Med Res 2008; 36 (Suppl 1): 1A-53A (Pubitemid 351255962)
23. Salminen S, Gueimonde M. Gut microbiota in infants between 6 and 24 months of age. Nestle Nutr Workshop Ser Pediatr Program 2005; 56: 43-51
24. Hopkins MJ, Sharp R, Macfarlane GT. Age and disease related changes in intestinal bacterial populations assessed by cell culture, 16S rRNA abundance, and community cellular fatty acid profiles. Gut 2001; 48: 198-205 (Pubitemid 32141843)
25. Woodmansey EJ. Intestinal bacteria and ageing. J Appl Microbiol 2007; 102: 1178-1186
26. Harmsen HJ, Wildeboer-Veloo AC, Grijpstra J et al. Development of 16S rRNA-based probes for the Coriobacterium group and the Atopobium cluster and their application for enumeration of Coriobacteriaceae in human feces from volunteers of different age groups. Appl Environ Microbiol 2000; 66: 4523-4527 (Pubitemid 30768556)
27. Saunier K, Dore J. Gastrointestinal tract and the elderly: functional foods, gut microflora and healthy ageing. Dig Liver Dis 2002; 34 (Suppl 2): S19-S24
28. Blaut M, Collins MD, Welling GW et al. Molecular biological methods for studying the gut microbiota: the EU human gut flora project. Br J Nutr 2002; 87 (Suppl 2): S203-S211 (Pubitemid 34685556)
29. He F, Ouwehand AC, Isolauri E et al. Differences in composition and mucosal adhesion of bifidobacteria isolated from healthy adults and healthy seniors. Curr Microbiol 2001; 43: 351-354 (Pubitemid 32973287)
30. Ouwehand AC, Isolauri E, Kirjavainen PV et al. Adhesion of four Bifidobacterium strains to human intestinal mucus from subjects in different age groups. FEMS Microbiol Lett 1999; 172: 61-64 (Pubitemid 29090291)
31. Eschenbach DA, Davick PR, Williams BL et al. Prevalence of hydrogen peroxide-producing Lactobacillus species in normal women and women with bacterial vaginosis. J Clin Microbiol 1989; 27: 251-256
32. Guigoz Y, Dore J, Schiffrin EJ. The inflammatory status of old age can be nurtured from the intestinal environment. Curr Opin Clin Nutr Metab Care 2008; 11: 13-20 (Pubitemid 350295220)
33. Hayashi H, Sakamoto M, Kitahara M et al. Molecular analysis of fecal microbiota in elderly individuals using 16S rDNA library and T-RFLP. Microbiol Immunol 2003; 47: 557-570 (Pubitemid 37010383)
34. Bouhnik Y, Raskine L, Simoneau G et al. The capacity of nondigestible carbohydrates to stimulate fecal bifidobacteria in healthy humans: a double-blind, randomized, placebo-controlled, parallel-group, dose-response relation study. Am J Clin Nutr 2004; 80: 1658-1664 (Pubitemid 41103868)
35. Palframan RJ, Gibson GR, Rastall RA. Carbohydrate preferences of Bifidobacterium species isolated from the human gut. Curr Issues Intest Microbiol 2003; 4: 71-75
36. Roberfroid MB, Van Loo JA, Gibson GR. The bifidogenic nature of chicory inulin and its hydrolysis products. J Nutr 1998; 128: 11-19
37. Liu C, Song Y, McTeague M et al. Rapid identification of the species of the Bacteroides fragilis group by multiplex PCR assays using group- and species-specific primers. FEMS Microbiol Lett 2003; 222: 9-16 (Pubitemid 36577346)