Increased DNA methylation near TREM2 is consistently seen in the superior temporal gyrus in Alzheimer's disease brain

Neurobiology of Aging

Volumn 47, Issue , 2016, Pages 35-40

  Smith, Adam R ^a   Smith, Rebecca G ^a   Condliffe, Daniel ^b   Hannon, Eilis ^a   Schalkwyk, Leonard ^c   Mill, Jonathan ^a,d   Lunnon, Katie ^a  

^a UNIVERSITY OF EXETER MEDICAL SCHOOL   (United Kingdom)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^c UNIVERSITY OF ESSEX   (United Kingdom)

^d KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

AD; Alzheimer's disease; Braak stage; Brain; DNA methylation; Epigenetics; TREM2

Indexed keywords

GENOMIC DNA; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2; IMMUNOGLOBULIN RECEPTOR; MEMBRANE PROTEIN; TREM2 PROTEIN, HUMAN;

ALZHEIMER DISEASE; ARTICLE; BRAIN TISSUE; COHORT ANALYSIS; CPG ISLAND; DNA ISOLATION; DNA METHYLATION; GENE DISRUPTION; GENE LOCUS; GENE MUTATION; GENOTYPE; HUMAN; PRIORITY JOURNAL; PYROSEQUENCING; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM; SUPERIOR TEMPORAL GYRUS; TRANSCRIPTION INITIATION SITE; TREM2 GENE; AGED; FEMALE; GENETIC ASSOCIATION STUDY; GENETIC EPIGENESIS; GENETICS; MALE; META ANALYSIS (TOPIC); METABOLISM; MIDDLE AGED; TEMPORAL LOBE; VERY ELDERLY;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; COHORT STUDIES; CPG ISLANDS; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; GENETIC ASSOCIATION STUDIES; HUMANS; MALE; MEMBRANE GLYCOPROTEINS; META-ANALYSIS AS TOPIC; MIDDLE AGED; RECEPTORS, IMMUNOLOGIC; TEMPORAL LOBE;

EID: 84981487656     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2016.07.008     Document Type: Article

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