Astilbin improves potassium oxonate-induced hyperuricemia and kidney injury through regulating oxidative stress and inflammation response in mice

Biomedicine and Pharmacotherapy

Volumn 83, Issue , 2016, Pages 975-988

  Wang, Ming ^a   Zhao, Jing ^b   Zhang, Nan ^a   Chen, Jianghua ^c  

^a THE SECOND AFFILIATED HOSPITAL OF ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b Zhaohui Community Health Service Center   (China)

^c ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Astilbin; Hyperuricemia; Potassium oxonate; Renal injury; TXNIP

Indexed keywords

ASTILBIN; BREAST CANCER RESISTANCE PROTEIN; CARNITINE TRANSPORTER 1; CARNITINE TRANSPORTER 2; CREATININE; CRYOPYRIN; GLUCOSE TRANSPORTER; GLUCOSE TRANSPORTER 9; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 6; JANUS KINASE 2; ORGANIC ANION TRANSPORTER 1; ORGANIC ANION TRANSPORTER 3; ORGANIC CATION TRANSPORTER 1; OTERACIL POTASSIUM; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; THIOREDOXIN INTERACTING PROTEIN; UNCLASSIFIED DRUG; URATE; URATE TRANSPORTER; URATE TRANSPORTER 1; URIC ACID; CARRIER PROTEIN; FLAVONOL DERIVATIVE; INFLAMMASOME; NLRP3 PROTEIN, MOUSE; OTERACIL; THIOREDOXIN; TXNIP PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; CREATININE URINE LEVEL; DOSE RESPONSE; FRACTIONAL EXCRETION; HYPERURICEMIA; INFLAMMATION; KIDNEY FUNCTION; KIDNEY INJURY; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PODOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RENAL PROTECTION; SARSAPARILLA; SIGNAL TRANSDUCTION; UPREGULATION; UREA NITROGEN BLOOD LEVEL; URIC ACID BLOOD LEVEL; URIC ACID URINE LEVEL; ANIMAL; BLOOD; CHEMICALLY INDUCED; CHEMISTRY; DRUG EFFECTS; KIDNEY; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY;

ANIMALS; CARRIER PROTEINS; FLAVONOLS; HYPERURICEMIA; INFLAMMASOMES; INFLAMMATION; JANUS KINASE 2; KIDNEY; MALE; MEMBRANE TRANSPORT PROTEINS; MICE; NF-KAPPA B; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; OXIDATIVE STRESS; OXONIC ACID; PODOCYTES; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; THIOREDOXINS; URIC ACID;

EID: 84981351769     PISSN: 07533322     EISSN: 19506007     Source Type: Journal    
DOI: 10.1016/j.biopha.2016.07.025     Document Type: Article

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