Astilbin suppresses collagen-induced arthritis via the dysfunction of lymphocytes

Inflammation Research

Volumn 52, Issue 8, 2003, Pages 334-340

  Cai, Y ^a,b   Chen, T ^a   Xu, Q ^a,b  

^a NANJING UNIVERSITY   (China)

^b CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Astilbin; Collagen induced arthritis; Cyclosporine A; Lymphocyte; Matrix metalloproteinases

Indexed keywords

ASTILBIN; COLLAGEN; CYCLOSPORIN A; MATRIX METALLOPROTEINASE; SMILACIS GLABRAE EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTHRITIS; ARTICLE; BODY WEIGHT; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; FOOT PAD; LIMB SWELLING; LYMPHOCYTE; LYMPHOCYTE FUNCTION; MALE; MOUSE; NONHUMAN; SCORING SYSTEM; SMILACACEAE; SMILACIS GLABRAE;

ANIMALS; ANTIRHEUMATIC AGENTS; ARTHRITIS, EXPERIMENTAL; CONCANAVALIN A; CYCLOSPORINE; DRUGS, CHINESE HERBAL; FLAVONOLS; HINDLIMB; LYMPHOCYTES; MALE; MATRIX METALLOPROTEINASES; MICE; MICE, INBRED STRAINS; NITRIC OXIDE; SPLEEN;

EID: 0041662012     PISSN: 10233830     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00011-003-1179-3     Document Type: Article

References (34)

1. Bradley JD, Brandt KD, Katz BP. Infectious complications of cyclophosphamide treatment for vasculitis. Arthritis Rheum 1989; 32: 45-53.
2. Donadio JV Jr, Holley KE, Ferguson RH, Ilstrup DM. Treatment of diffuse proliferative lupus nephritis with prednisone and combined prednisone and cyclophosphamide. N Engl J Med 1978; 299: 1151-5.
3. Furst DE, Erikson N, Clute L, Koehnke R, Burmeister LF, Kohler JA. Adverse experience with methotrexate during 176 weeks of a long term prospective trial in patients with rheumatoid arthritis. J Rheumatol 1990; 17: 1628-35.
4. Gijtenbeek JM, van den Bent MJ, Vecht CJ. Cyclosporine neurotoxicity: a review. J Neurol 1999; 246: 339-46.
5. Mihatsch MJ, Kyo M, Morozumi K, Yamaguchi Y, Nickeleit V, Ryffel B. The side-effects of cyclosporine-A and tacrolimus. Clin Nephrol 1998; 49: 356-63.
6. Damoiseaux JG, Beijleveld LJ, van Breda Vriesman PJ. Multiple effects of cyclosporin A on the thymus in relation to T-cell development and autoimmunity. Clin Immunol Immunopathol 1997; 82: 197-202.
7. Milicevic NM, Milicevic Z. Cyclosporin A-induced changes of the thymic microenvironment. A review of morphological studies. Histol Histopathol 1998; 13: 1183-96.
8. Viola JP, Rao A. Role of the cyclosporin-sensitive transcription factor NFAT1 in the allergic response. Mem Inst Oswaldo Cruz 1997; 92 Suppl. 2: 147-55.
9. Xu Q, Zhao H, Hang B. Inhibition of delayed type hypersensitivity reactions by Fructus Tribuli. J China Pharmaceut Univ 1991; 22: 12-6. (Abstract in English)
10. Xu Q, Xu L. Inhibition of delayed type hypersensitivity reactions by Radix Gentianae. Pharmacol Clin Chin Materia 1993; 9: 25-6.
11. Xu Q, Yuan K, Lu J, Wang R, Wu F. A new strategy for regulating the immunological liver injury - effectiveness of DTH-inhibiting agents on DTH-induced liver injury to picryl chloride. Pharmacol Res 1997; 36: 401-9.
12. Xu Q, Wang R, Xu L, Jiang J. Effects of Rhizoma Simlacis Glabrae on cellular and humoral immune responses. Chin J Immunol 1993; 9: 39-42. (Abstract in English)
13. Batista Pereira LG, Petacci F, Fernandes JB, Correa AG, Vieira PC, da Silva MF, et al. Biological activity of astilbin from Dimorphandra mollis against Anticarsia gemmatalis and Spodoptera frugiperda. Pest Manag Sci 2002; 58: 503-7.
14. Chen TH, Liu JC, Chang JJ, Tsai MF, Hsieh MH, Chan P. The in vitro inhibitory effect of flavonoid astilbin on 3-hydroxy-3-methylglutaryl coenzyme A reductase on Vero cells. Zhonghua Yi Xue Za Zhi (Taipei) 2001; 64: 382-7.
15. Haraguchi H, Ohmi I, Fukuda A, Tamura Y, Mizutani K, Tanaka O et al. Inhibition of aldose reductase and sorbitol accumulation by astilbin and taxifolin dihydroflavonols in Engelhardtia chrysolepis. Biosci Biotechnol Biochem 1997; 61: 651-4.
16. 4C-induced hepatotoxicity in rats: effect of astilbin. Prostaglandins Leukot Essent Fatty Acids 1997; 56: 331-4.
17. Cechinel-Filho V, Vaz ZR, Zunino L, Calixto JB, Yunes RA. Antinociceptive and anti-oedematogenic properties of astilbin, taxifolin and some related compounds. Arzneimittelforschung 2000; 50: 281-5.
18. Haraguchi H, Mochida Y, Sakai S, Masuda H, Tamura Y, Mizutani K, et al. Protection against oxidative damage by dihydroflavonols in Engelhardtia chrysolepis. Biosci Biotechnol Biochem 1996; 60: 945-8.
19. Igarashi K, Uchida Y, Murakami N, Mizutani K, Masuda H. Effect of astilbin in tea processed from leaves of Engelhardtia chrysolepis on the serum and liver lipid concentrations and on the erythrocyte and liver antioxidative enzyme activities of rats. Biosci Biotechnol Biochem 1996; 60: 513-5.
20. Xu Q, Wu F, Cao J, Chen T, Jiang J, Saiki I et al. Astilbin selectively induces dysfunction of liver-infiltrating cells - novel protection from liver damage. Eur J Pharmacol 1999; 377: 93-100.
21. Yan R, Xu Q. Astilbin selectively facilitates the apoptosis of interleukin-2-dependent phytohemagglutinin-activated Jurkat cells. Pharmacol Res 2001; 44: 135-9.
22. Chen T, Li J, Cao J, Xu Q, Komatsu K, Namba T. A new flavanone isolated from Rhizoma Smilacis Glabrae and the structural requirements of its derivatives for preventing immunological hepatocyte damage. Planta Med 1999; 65: 56-9.
23. Rosoniec EF, Cremer M, Kang A, Myers LK. Collagen-induced arthritis. In: Coligan JE, Kruisbeek AM, Margulies DH, Shevach EM, Strober W, editors. Current Protocols in Immunology. New York 1996: p.15.5.1.
24. Aoudjit F, Esteve PO, Desrosiers M, Potworowski EF, St-Pierre Y. Gelatinase B (MMP) production and expression by stromal cells in the normal and adult thymus and experimental thymic lymphoma. Int J Cancer 1997; 71: 71-8.
25. Panayi GS, Lanchbury JS, Kingsley GH. The importance of the T cell in initiating and maintaining the chronic synovitis of rheumatoid arthritis. Arthritis Rheum 1992; 35: 729-35.
26. Plows D, Kontogeorgos G, and Kollias G. Mice lacking mature T and B lymphocytes develop arthritic lesions after immunization with type II collagen. J Immunol 1999; 162: 1018-23.
27. Doncarli A, Stasiuk LM, Fournier C, Abehsira-Amar O. Conversion in vivo from an early dominant Th0/Th1 response to a Th2 phenotype during the development of collagen-induced arthritis. Eur J Immunol 1997; 27: 1451-8.
28. Leppert D, Waubant E, Galardy R, Bunnett NW, Hauser SL. T cell gelatinases mediate basement membrane transmigration in vitro. J Immunol 1995; 154: 4379-89.
29. Cherla RP, Ganju RK. Stromal cell-derived factor 1 alpha-induced chemotaxis in T cells is mediated by nitric oxide signaling pathways. J Immunol 2001; 166: 3067-74.
30. Sugaya T, Ishizu A, Ikeda H, Nakamaru Y, Fugo K, Higuchi M, et al. Clonotypic analysis of T cells accumulating at arthritic lesions in HTLV-I env-pX transgenic rats. Exp Mol Pathol 2002; 72: 56-61.
31. Springer TA. Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm. Cell 1994; 76: 301-14.
32. 3 integrin involved in adhesion of leukocytes to endothelium. J Cell Biol 1995; 130: 451-60.
33. Cid MC, Esparza J, Juan M, Miralles A, Ordi J, Vilella R, et al. Signaling through CD50 (ICAM-3) stimulates T lymphocyte binding to human umbilical vein endothelial cells and extracellular matrix proteins via an increase in beta1 and beta2 integrin function. Eur J Immunol 1994; 24: 1377-82.
34. Bianchi E, Bender JR, Blasi F, Pardi R. Through and beyond the wall: Late steps in leukocyte transendothelail migration. Immunol Today 1997; 18: 586-91.