Inhibition of cardiomyocytes hypertrophy by resveratrol is associated with amelioration of endoplasmic reticulum stress

Cellular Physiology and Biochemistry

Volumn 39, Issue 2, 2016, Pages 780-789

  Lin, Yan ^a   Zhu, Jingbin ^b   Zhang, Xiaojie ^a   Wang, Jun ^a   Xiao, Wei ^a   Li, Bo ^a   Jin, Li ^a   Lian, Jie ^a   Zhou, Li ^a   Liu, Jicheng ^a  

^a QIQIHAR MEDICAL UNIVERSITY   (China)

^b First Hospital of Harbin   (China)

Author keywords

Apoptosis; Cardiac hypertrophy; Endoplasmic reticulum stress; Resveratrol

Indexed keywords

4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; ATRIAL NATRIURETIC FACTOR; GLUCOSE REGULATED PROTEIN 78; GLUCOSE REGULATED PROTEIN 94; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; ISOPRENALINE; LACTATE DEHYDROGENASE; MALONALDEHYDE; PROTEIN BAX; PROTEIN BCL 2; RESVERATROL; ANTIOXIDANT; BAX PROTEIN, RAT; CARDIOTONIC AGENT; HEAT SHOCK PROTEIN; HSPA5 PROTEIN, RAT; STILBENE DERIVATIVE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CARDIAC MUSCLE CELL; CELL SURFACE; CELL SURVIVAL; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION; GROWTH INHIBITION; HEART PROTECTION; HEART VENTRICLE HYPERTROPHY; IMMUNOHISTOCHEMISTRY; MEDIATOR; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; STAINING; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING; ANIMAL; CARDIOMEGALY; CELL CULTURE; CELL SIZE; CYTOLOGY; DRUG EFFECTS; GENETICS; METABOLISM; NEWBORN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WISTAR RAT;

ANIMALS; ANIMALS, NEWBORN; ANTIOXIDANTS; APOPTOSIS; ATRIAL NATRIURETIC FACTOR; BCL-2-ASSOCIATED X PROTEIN; BLOTTING, WESTERN; CARDIOMEGALY; CARDIOTONIC AGENTS; CELL SIZE; CELLS, CULTURED; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION; HEAT-SHOCK PROTEINS; ISOPROTERENOL; MICROSCOPY, ELECTRON, TRANSMISSION; MYOCYTES, CARDIAC; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STILBENES;

EID: 84981320702     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000447788     Document Type: Article

References (36)

1. Peng K, Tian X, Qian Y, Skibba M, Zou C, Liu Z, Wang J, Xu Z, Li X, Liang G: Novel EGFR inhibitors attenuate cardiac hypertrophy induced by angiotensin II. J Cell Mol Med 2016;20:482-494.
2. Rao RV, Ellerby HM, Bredesen DE: Coupling endoplasmic reticulum stress to the cell death program. Cell Death Differ 2004;11:372-380.
3. Szegezdi E, Fitzgerald U, Samali A: Caspase-12 and ER-stress-mediated apoptosis: The story so far. Ann N Y Acad Sci 2003;1010:186-194.
4. 231 ameliorates cardiac hypertrophy by inhibiting cellular autophagy in vivo and in vitro. Cell Physiol Biochem 2015;36:1597-1612.
5. Okada K, Minamino T, Tsukamoto Y, Liao Y, Tsukamoto O, Takashima S, Hirata A, Fujita M, Nagamachi Y, Nakatani T, Yutani C, Ozawa K, Ogawa S, Tomoike H, Hori M, Kitakaze M: Prolonged endoplasmic reticulum stress in hypertrophic and failing heart after aortic constriction: possible contribution of endoplasmic reticulum stress to cardiac myocyte apoptosis. Circulation 2004;110:705-712.
6. Rojas C, Pan-Castillo B, Valls C, Pujadas G, Garcia-Vallve S, Arola L, Mulero M: Resveratrol enhances palmitate-induced ER stress and apoptosis in cancer cells. PLoS One 2014;9:e113929.
7. Hsieh DJ, Kuo WW, Lai YP, Shibu MA, Shen CY, Pai P, Yeh YL, Lin JY, Viswanadha VP, Huang CY: 17β-estradiol and/or estrogen receptor β attenuate the autophagic and apoptotic effects induced by prolonged hypoxia through HIF-1α-mediated BNIP3 and IGFBP-3 signaling blockage. Cell Physiol Biochem 2015;36:274-284.
8. Li Y, Xu S, Giles A, Nakamura K, Lee JW, Hou X, Donmez G, Li J, Luo Z, Walsh K, Guarente L, Zang M: Hepatic overexpression of sirt1 in mice attenuates endoplasmic reticulum stress and insulin resistance in the liver. FASEB J 2011;25:1664-1679.
9. Qi HP, Wang Y, Zhang QH, Guo J, Li L, Cao YG, Li SZ, Li XL, Shi MM, Xu W, Li BY, Sun HL: Activation of peroxisome proliferator-activated receptor γ (PPARγ) through NF-κB/Brg1 and TGF-β1 pathways attenuates cardiac remodeling in pressure-overloaded rat hearts. Cell Physiol Biochem 2015;35:899-912.
10. Lin Y, Zhang X, Wang L, Zhao Y, Li H, Xiao W, Xu C, Liu J: Polyamine depletion attenuates isoproterenol-induced hypertrophy and endoplasmic reticulum stress in cardiomyocytes. Cell Physiol Biochem 2014;34:1455-1465.
11. Zhao YJ, Zhang WH, Xu CQ, Li HZ, Wang LN, Li H, Sun YH, Lin Y, Han LP, Zhang L, Tian Y, Wang R, Yang BF, Li WM: Involvement of the ornithine decarboxylase/polyamine system in precondition-induced cardioprotection through an interaction with pkc in rat hearts. Mol Cell Biochem 2009;332:135-144.
12. Lin Y, Wang LN, Xi YH, Li HZ, Xiao FG, Zhao YJ, Tian Y, Yang BF, Xu CQ: L-arginine inhibits isoproterenol-induced cardiac hypertrophy through nitric oxide and polyamine pathways. Basic Clin Pharmacol Toxicol 2008;103:124-130.
13. Groenning BA, Nilsson JC, Sondergaard L, Fritz-Hansen T, Larsson HB, Hildebrandt PR: Antiremodeling effects on the left ventricle during beta-blockade with metoprolol in the treatment of chronic heart failure. J Am Coll Cardiol 2000;36:2072-2080.
14. Park CS, Cha H, Kwon EJ, Sreenivasaiah PK, Kim DH: The chemical chaperone 4-phenylbutyric acid attenuates pressure-overload cardiac hypertrophy by alleviating endoplasmic reticulum stress. Biochem Biophys Res Commun 2012;421:578-584.
15. Shetty S, Gladden JB, Henson ES, Hu X, Villanueva J, Haney N, Gibson SB: Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) up-regulates death receptor 5 (DR5) mediated by nfkappab activation in epithelial derived cell lines. Apoptosis 2002;7:413-420.
16. Pérez-Treviño P, Pérez-Treviño J, Borja-Villa C, García N, Altamirano J: Changes in T-tubules and sarcoplasmic reticulum in ventricular myocytes in early cardiac hypertrophy in a pressure overload rat model. Cell Physiol Biochem 2015;37:1329-1344.
17. Voelkl J, Castor T, Musculus K, Viereck R, Mia S, Feger M, Alesutan I, Lang F: SGK1-sensitive regulation of cyclin-dependent kinase inhibitor 1B (p27) in cardiomyocyte hypertrophy. Cell Physiol Biochem 2015;37:603-614.
18. Kemp TJ, Moore JM, Griffith TS: Human B cells express functional TRAIL/Apo-2 ligand after CpG-containing oligodeoxynucleotide stimulation. J Immunol 2004;173:892-899.
19. Dolinsky VW, Chakrabarti S, Pereira TJ, Oka T, Levasseur J, Beker D, Zordoky BN, Morton JS, Nagendran J, Lopaschuk GD, Davidge ST, Dyck JR: Resveratrol prevents hypertension and cardiac hypertrophy in hypertensive rats and mice. Biochim Biophys Acta 2013;1832:1723-1733.
20. Chen YR, Yi FF, Li XY, Wang CY, Chen L, Yang XC, Su PX, Cai J: Resveratrol attenuates ventricular arrhythmias and improves the long-term survival in rats with myocardial infarction. Cardiovasc Drugs Ther 2008;22:479-485.
21. Dolinsky VW, Soltys CL, Rogan KJ, Chan AY, Nagendran J, Wang S, Dyck JR: Resveratrol prevents pathological but not physiological cardiac hypertrophy. J Mol Med (Berl) 2015;93:413-425.
22. Sung MM, Das SK, Levasseur J, Byrne NJ, Fung D, Kim TT, Masson G, Boisvenue J, Soltys CL, Oudit GY, Dyck JR: Resveratrol treatment of mice with pressure-overload-induced heart failure improves diastolic function and cardiac energy metabolism. Circ Heart Fail 2015;8:128-137.
23. Qin F, Siwik DA, Pimentel DR, Morgan RJ, Biolo A, Tu VH, Kang YJ, Cohen RA, Colucci WS: Cytosolic H2O2 mediates hypertrophy, apoptosis, and decreased serca activity in mice with chronic hemodynamic overload. Am J Physiol Heart Circ Physiol 2014;306:H1453-1463.
24. Liu Y, Liu Q, Hu Z, Shen Q, Liang H, Jiang X: Resveratrol attenuated homocysteine-induced apoptosis of rat ventricular myocytes. Int J Cardiol 2014;177:298-300.
25. Shen M, Jia GL, Wang YM, Ma H: Cardioprotective effect of resvaratrol pretreatment on myocardial ischemia-reperfusion induced injury in rats. Vascul Pharmacol 2006;45:122-126.
26. Krajewski S, Tanaka S, Takayama S, Schibler MJ, Fenton W, Reed JC: Investigation of the subcellular distribution of the bcl-2 oncoprotein. Residence in the nuclear envelope, endoplasmic reticulum, and outer mitochondrial membranes. Cancer Res 1993;53:4701-4714.
27. Reed JC: Bcl-2 family proteins. Oncogene 1998;17:3225-3236.
28. Whelan RS, Kaplinskiy V, Kitsis RN: Cell death in the pathogenesis of heart disease: mechanisms and significance. Annu Rev Physiol 2010;72:19-44.
29. Yin K, Zhao L, Feng D, Ma W, Liu Y, Wang Y, Liang J, Yang F, Bi C, Chen H, Li X, Lu Y, Cai B: Resveratrol attenuated low ambient temperature-induced myocardial hypertrophy via inhibiting cardiomyocyte apoptosis. Cell Physiol Biochem 2015;35:2451-2462.
30. Glembotski CC: The role of the unfolded protein response in the heart. J Mol Cell Cardiol 2008;44:453-459.
31. Brostrom MA, Mourad F, Brostrom CO: Regulated expression of GRP78 during vasopressin-induced hypertrophy of heart-derived myocytes. J Cell Biochem 2001;83:204-217.
32. Sari FR, Widyantoro B, Thandavarayan RA, Harima M, Lakshmanan AP, Zhang S, Muslin AJ, Suzuki K, Kodama M, Watanabe K: Attenuation of CHOP-mediated myocardial apoptosis in pressure-overloaded dominant negative p38α mitogen-activated protein kinase mice. Cell Physiol Biochem 2011;27:487-496.
33. Oyadomari S, Mori M: Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ 2004;11:381-389.
34. Zinszner H, Kuroda M, Wang X, Batchvarova N, Lightfoot RT, Remotti H, Stevens JL, Ron D: CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum. Genes Dev 1998;12:982-995.
35. Lou Y, Wang Z, Xu Y, Zhou P, Cao J, Li Y, Chen Y, Sun J, Fu L: Resveratrol prevents doxorubicin-induced cardiotoxicity in H9C2 cells through the inhibition of endoplasmic reticulum stress and the activation of the sirt1 pathway. Int J Mol Med 2015;36:873-880.
36. Pan QR, Ren YL, Liu WX, Hu YJ, Zheng JS, Xu Y, Wang G: Resveratrol prevents hepatic steatosis and endoplasmic reticulum stress and regulates the expression of genes involved in lipid metabolism, insulin resistance, and inflammation in rats. Nutr Res 2015;35:576-584.