Effect of overproduction of mitochondrial uncoupling protein 2 on cos7 cells: Induction of senescent-like morphology and oncotic cell death

Current Aging Science

Volumn 9, Issue 3, 2016, Pages 229-238

  Nishio, Koji ^a   Ma, Qian ^b  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Cellular senescence; Cos7 cells and oncotic cell death; Mitochondrial carrier family; Mitochondrial membrane potential; Senescent morphology; UCP2

Indexed keywords

ANTIBIOTIC AGENT; ANTIMYCIN A1; GENECITIN; GREEN FLUORESCENT PROTEIN; MITOCHONDRIAL PROTEIN; MUTANT PROTEIN; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 2; ADENOSINE TRIPHOSPHATE; HYBRID PROTEIN; REACTIVE OXYGEN METABOLITE; UCP2 PROTEIN, HUMAN; UCP2 PROTEIN, MOUSE;

ACUTE TOXICITY; ANIMAL CELL; ARTICLE; BIOLOGICAL ACTIVITY; CELL AGING; CELL DEATH; CELL LYSATE; CELL SHAPE; CELL STRUCTURE; CONTROLLED STUDY; COS 7 CELL LINE; DOWN REGULATION; GENE OVEREXPRESSION; HUMAN; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; OXIDATIVE PHOSPHORYLATION UNCOUPLING; PHASE CONTRAST MICROSCOPY; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN STABILITY; WESTERN BLOTTING; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL; BIOSYNTHESIS; CHEMISTRY; CHLOROCEBUS AETHIOPS; CV-1 CELL LINE; GENETIC TRANSFECTION; GENETICS; METABOLISM; MITOCHONDRION; MOUSE; SITE DIRECTED MUTAGENESIS;

ADENOSINE TRIPHOSPHATE; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; CELL DEATH; CELL SHAPE; CELLULAR SENESCENCE; CERCOPITHECUS AETHIOPS; COS CELLS; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MITOCHONDRIA; MUTAGENESIS, SITE-DIRECTED; REACTIVE OXYGEN SPECIES; RECOMBINANT FUSION PROTEINS; TRANSFECTION; UNCOUPLING PROTEIN 2;

EID: 84981295207     PISSN: 18746098     EISSN: 18746128     Source Type: Journal    
DOI: 10.2174/1874609809666160211125332     Document Type: Article

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