The Role of Molecular Diagnostics in the Management of Patients with Gliomas

Current Treatment Options in Oncology

Volumn 17, Issue 10, 2016, Pages

  Wirsching, Hans Georg ^a   Weller, Michael ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

Astrocytoma; Diffuse glioma; Ependymoma; Glioblastoma; Molecular marker; Oligodendroglioma; Pilocytic astrocytoma; Targeted therapy; WHO classification

Indexed keywords

BEVACIZUMAB; CARBOPLATIN; EVEROLIMUS; GLYCINE; HISTONE H3; ISOCITRATE DEHYDROGENASE; LAPATINIB; LOMUSTINE; LYSINE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; PROCARBAZINE; SELUMETINIB; TELOMERASE REVERSE TRANSCRIPTASE; TEMOZOLOMIDE; TEMSIROLIMUS; VEMURAFENIB; VINCRISTINE; HISTONE; TUMOR MARKER;

ASTROCYTIC GLIOMA; CANCER CHEMOTHERAPY; CANCER CLASSIFICATION; CANCER COMBINATION CHEMOTHERAPY; CANCER DIAGNOSIS; CANCER GENETICS; CANCER GRADING; CANCER GROWTH; CANCER PATIENT; CANCER SURVIVAL; CHROMOSOME 19Q; CHROMOSOME 1P; CHROMOSOME DELETION; DIFFUSE OLIGODENDROGLIAL GLIOMA; DRUG EFFICACY; DRUG TREATMENT FAILURE; EPENDYMOMA; EPIGENETICS; GENE EXPRESSION; GENE MUTATION; GENETIC HETEROGENEITY; GENOMIC INSTABILITY; GLIOBLASTOMA; GLIOMA; H3F3A GENE; HISTOPATHOLOGY; HUMAN; IDH GENE; MEDICAL DECISION MAKING; MGMT GENE; MOLECULAR DIAGNOSTICS; MOLECULARLY TARGETED THERAPY; OLIGODENDROGLIOMA; PERSONALIZED MEDICINE; PHARMACODYNAMICS; PHARMACOKINETICS; PILOCYTIC ASTROCYTOMA; PLEOMORPHIC XANTHOASTROCYTOMA; PREDICTION; PROMOTER REGION; REVIEW; SUBEPENDYMAL GIANT CELL ASTROCYTOMA; TERT GENE; WORLD HEALTH ORGANIZATION; BRAIN NEOPLASMS; CANCER STAGING; CELL TRANSFORMATION; CHROMOSOME ABERRATION; DISEASE MANAGEMENT; DNA METHYLATION; GENETICS; METABOLISM; MOLECULAR DIAGNOSIS; MORTALITY; MUTATION; TREATMENT OUTCOME;

BIOMARKERS, TUMOR; BRAIN NEOPLASMS; CELL TRANSFORMATION, NEOPLASTIC; CHROMOSOME ABERRATIONS; DISEASE MANAGEMENT; DNA METHYLATION; GLIOMA; HISTONES; HUMANS; MOLECULAR DIAGNOSTIC TECHNIQUES; MOLECULAR TARGETED THERAPY; MUTATION; NEOPLASM GRADING; NEOPLASM STAGING; PROMOTER REGIONS, GENETIC; TREATMENT OUTCOME;

EID: 84981275124     PISSN: 15272729     EISSN: 15346277     Source Type: Journal    
DOI: 10.1007/s11864-016-0430-4     Document Type: Review

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