메뉴 건너뛰기




Volumn 6, Issue , 2016, Pages

Role of Keap1-Nrf2 signaling in depression and dietary intake of glucoraphanin confers stress resilience in mice

Author keywords

[No Author keywords available]

Indexed keywords

GLUCORAPHANIN; GLUCOSINOLATE; IMIDOESTER; KEAP1 PROTEIN, MOUSE; KELCH LIKE ECH ASSOCIATED PROTEIN 1; NEUROPROTECTIVE AGENT; NFE2L2 PROTEIN, MOUSE; TRANSCRIPTION FACTOR NRF2;

EID: 84979935392     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep30659     Document Type: Article
Times cited : (129)

References (76)
  • 1
    • 84887259083 scopus 로고    scopus 로고
    • Global burden of disease attributable to mental and substance use disorders: Findings from the Global Burden of Disease Study 2010
    • Whiteford, H. A. et al. Global burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010. Lancet 382, 1575-1586 (2013).
    • (2013) Lancet , vol.382 , pp. 1575-1586
    • Whiteford, H.A.1
  • 2
    • 84928023204 scopus 로고    scopus 로고
    • Mortality in mental disorders and global disease burden implications: A systematic review and meta-analysis
    • Walker, E. R., McGee, R. E., Druss, B. G. Mortality in mental disorders and global disease burden implications: a systematic review and meta-analysis. JAMA Psychiatry 72, 334-341 (2015).
    • (2015) JAMA Psychiatry , vol.72 , pp. 334-341
    • Walker, E.R.1    McGee, R.E.2    Druss, B.G.3
  • 3
    • 77951077887 scopus 로고    scopus 로고
    • Dietary intake and depressive symptoms: A systemic review of observational studies
    • Mukakami, K., Sasaki, S. Dietary intake and depressive symptoms: a systemic review of observational studies. Mol Nutr Food Res. 54, 471-488 (2010).
    • (2010) Mol Nutr Food Res , vol.54 , pp. 471-488
    • Mukakami, K.1    Sasaki, S.2
  • 4
    • 84922479473 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids and their metabolites in brain function and disease
    • Bazinet, R. P., Layé, S. Polyunsaturated fatty acids and their metabolites in brain function and disease. Nat Rev Neurosci 15, 771-785 (2014).
    • (2014) Nat Rev Neurosci , vol.15 , pp. 771-785
    • Bazinet, R.P.1    Layé, S.2
  • 5
    • 84900300344 scopus 로고    scopus 로고
    • 3 and major Depression: A review
    • Mello, A. H. et al. ?-3 and major depression: a review. Acta Neuropsychiatr 26, 178-185 (2014).
    • (2014) Acta Neuropsychiatr , vol.26 , pp. 178-185
    • Mello, A.H.1
  • 6
    • 84925283645 scopus 로고    scopus 로고
    • Maternal depression, stress and feeding styles: Towards a framework for theory and research in child obesity
    • El-Behadli, A. F. et al. Maternal depression, stress and feeding styles: towards a framework for theory and research in child obesity. Br J Nutr 113, S55-S71 (2015).
    • (2015) Br J Nutr , vol.113 , pp. S55-S71
    • El-Behadli, A.F.1
  • 7
    • 84937022411 scopus 로고    scopus 로고
    • The impact of whole-of-diet interventions on depression and anxiety: A systematic review of randomised controlled trials
    • Opie, A., O'Neil, R. S., Itsiopoulos, C., Jacka, F. N. The impact of whole-of-diet interventions on depression and anxiety: a systematic review of randomised controlled trials. Public Health Nutr 18, 2074-2093 (2015).
    • (2015) Public Health Nutr , vol.18 , pp. 2074-2093
    • Opie, A.1    O'Neil, R.S.2    Itsiopoulos, C.3    Jacka, F.N.4
  • 8
    • 84891438764 scopus 로고    scopus 로고
    • A systematic review and meta-analysis of dietary patterns and depression in community-dwelling adults
    • Lai, J. S. et al. A systematic review and meta-analysis of dietary patterns and depression in community-dwelling adults. Am J Clin Nutr. 99, 181-197 (2014).
    • (2014) Am J Clin Nutr , vol.99 , pp. 181-197
    • Lai, J.S.1
  • 9
    • 84961216298 scopus 로고    scopus 로고
    • Fruit and vegetable consumption and the risk of depression: A meta-analysis
    • Liu, X., Yan, Y., Li, F., Zhang, D. Fruit and vegetable consumption and the risk of depression: A meta-analysis. Nutrition 32, 296-302 (2016).
    • (2016) Nutrition , vol.32 , pp. 296-302
    • Liu, X.1    Yan, Y.2    Li, F.3    Zhang, D.4
  • 10
    • 56549127348 scopus 로고    scopus 로고
    • Why do many psychiatric disorders emerge during adolescence?
    • Paus, T., Keshavan, M., Giedd, J. N. Why do many psychiatric disorders emerge during adolescence? Nat Rev Neurosci 9, 947-957 (2008).
    • (2008) Nat Rev Neurosci , vol.9 , pp. 947-957
    • Paus, T.1    Keshavan, M.2    Giedd, J.N.3
  • 11
    • 84889592915 scopus 로고    scopus 로고
    • Adolescent brain vulnerability and psychopathology through the generations: Role of diet and dopamine
    • O'Connor, R. M., Cryan, J. F. Adolescent brain vulnerability and psychopathology through the generations: role of diet and dopamine. Biol Psychiatry 75, 4-6 (2014).
    • (2014) Biol Psychiatry , vol.75 , pp. 4-6
    • O'Connor, R.M.1    Cryan, J.F.2
  • 12
    • 37249094173 scopus 로고    scopus 로고
    • From inflammation to sickness and depression: When the immune system subjugates the brain
    • Dantzer, R. et al. From inflammation to sickness and depression: when the immune system subjugates the brain. Nature Rev Neurosci. 9, 46-57 (2008).
    • (2008) Nature Rev Neurosci , vol.9 , pp. 46-57
    • Dantzer, R.1
  • 13
    • 70349513258 scopus 로고    scopus 로고
    • Emerging role of glutamate in the pathophysiology of major depressive disorder
    • Hashimoto, K. Emerging role of glutamate in the pathophysiology of major depressive disorder. Brain Res Rev. 61, 105-123 (2009).
    • (2009) Brain Res Rev , vol.61 , pp. 105-123
    • Hashimoto, K.1
  • 14
    • 63449122724 scopus 로고    scopus 로고
    • Inflammation and its discontents: The role of cytokines in the pathophysiology of major depression
    • Miller, A. H., Maletic, V., Raison, C. L. Inflammation and its discontents: The role of cytokines in the pathophysiology of major depression. Biol Psychiatry 65, 732-741 (2009).
    • (2009) Biol Psychiatry , vol.65 , pp. 732-741
    • Miller, A.H.1    Maletic, V.2    Raison, C.L.3
  • 15
    • 78649955466 scopus 로고    scopus 로고
    • Inflammation sanitation, and Consternation: Loss of contact with coevolved, tolerogenic microorganisms and the pathophysiology and treatment of major depression
    • Raison, C. L., Lowry, C. A., Rook, G. A. Inflammation, sanitation, and consternation: loss of contact with coevolved, tolerogenic microorganisms and the pathophysiology and treatment of major depression. Arch Gen Psychiatry 67, 1211-1224 (2010).
    • (2010) Arch Gen Psychiatry , vol.67 , pp. 1211-1224
    • Raison, C.L.1    Lowry, C.A.2    Rook, G.A.3
  • 16
    • 84927667387 scopus 로고    scopus 로고
    • Inflammatory biomarkers as differential predictors of antidepressant response
    • Hashimoto, K. Inflammatory biomarkers as differential predictors of antidepressant response. Int J Mol Sci. 16, 7796-7801 (2015).
    • (2015) Int J Mol Sci , vol.16 , pp. 7796-7801
    • Hashimoto, K.1
  • 17
    • 84986877596 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor (BDNF)-TrkB signaling in inflammation-related depression and potential therapeutic targets
    • Zhang, J. C., Yao, W., Hashimoto, K. Brain-derived neurotrophic factor (BDNF)-TrkB signaling in inflammation-related depression and potential therapeutic targets. Curr Neuropharmacol doi: 10.2174/1570159X14666160119094646 (2016).
    • (2016) Curr Neuropharmacol
    • Zhang, J.C.1    Yao, W.2    Hashimoto, K.3
  • 18
    • 75849155537 scopus 로고    scopus 로고
    • A Meta-Analysis of cytokines in major depression
    • Dowlati, Y. et al. A meta-analysis of cytokines in major depression. Biol Psychiatry 67, 446-457 (2010).
    • (2010) Biol Psychiatry , vol.67 , pp. 446-457
    • Dowlati, Y.1
  • 19
    • 84906331370 scopus 로고    scopus 로고
    • A review of the relationship between pro-inflammatory cytokines and major depressive disorder
    • Young, J. J., Bruno, D., Pomara, N. A review of the relationship between pro-inflammatory cytokines and major depressive disorder. J Affect Disord 169, 15-20 (2014).
    • (2014) J Affect Disord , vol.169 , pp. 15-20
    • Young, J.J.1    Bruno, D.2    Pomara, N.3
  • 20
    • 84940609837 scopus 로고    scopus 로고
    • Cumulative meta-analysis of interleukins 6 and 1?, tumour necrosis factor ? and C-reactive protein in patients with major depressive disorder
    • Haapakoski, R. et al. Cumulative meta-analysis of interleukins 6 and 1?, tumour necrosis factor ? and C-reactive protein in patients with major depressive disorder. Brain Behav Immun 49, 206-215 (2015).
    • (2015) Brain Behav Immun , vol.49 , pp. 206-215
    • Haapakoski, R.1
  • 21
    • 71649086548 scopus 로고    scopus 로고
    • Regionally-Specific changes in levels of tumour necrosis factor in the dorsolateral prefrontal cortex obtained postmortem from subjects with major depressive disorder
    • Dean, B., Tawadros, N., Scarr, E., Gibbons, A. S. Regionally-specific changes in levels of tumour necrosis factor in the dorsolateral prefrontal cortex obtained postmortem from subjects with major depressive disorder. J Affect Disord 120, 245-248 (2010).
    • (2010) J Affect Disord , vol.120 , pp. 245-248
    • Dean, B.1    Tawadros, N.2    Scarr, E.3    Gibbons, A.S.4
  • 22
    • 79959611025 scopus 로고    scopus 로고
    • Altered expression of genes involved in inflammation and apoptosis in frontal cortex in major depression
    • Shelton, R. C. et al. Altered expression of genes involved in inflammation and apoptosis in frontal cortex in major depression. Mol Psychiatry 16, 751-762 (2011).
    • (2011) Mol Psychiatry , vol.16 , pp. 751-762
    • Shelton, R.C.1
  • 23
    • 84867034260 scopus 로고    scopus 로고
    • Role of nrf2 in oxidative stress and toxicity
    • Ma, Q. Role of nrf2 in oxidative stress and toxicity. Annu Rev Pharmacol Toxicol 53, 401-426 (2013).
    • (2013) Annu Rev Pharmacol Toxicol , vol.53 , pp. 401-426
    • Ma, Q.1
  • 24
    • 84879344989 scopus 로고    scopus 로고
    • Roles nrf2 plays in myeloid cells and related disorders
    • Kobayashi, E., Suzuki, T., Yamamoto, M. Roles nrf2 plays in myeloid cells and related disorders. Oxid Med Cell Longev 2013, 529219 (2013).
    • (2013) Oxid Med Cell Longev , vol.2013 , pp. 529219
    • Kobayashi, E.1    Suzuki, T.2    Yamamoto, M.3
  • 25
    • 84878572136 scopus 로고    scopus 로고
    • Toward clinical application of the Keap1-Nrf2 pathway
    • Suzuki, T., Motohashi, H., Yamamoto, M. Toward clinical application of the Keap1-Nrf2 pathway. Trends Pharmacol Sci. 34, 340-346 (2013).
    • (2013) Trends Pharmacol Sci , vol.34 , pp. 340-346
    • Suzuki, T.1    Motohashi, H.2    Yamamoto, M.3
  • 26
    • 84971291437 scopus 로고    scopus 로고
    • Molecular basis of the Keap1-Nrf2 system
    • Suzuki, T., Yamamoto, M. Molecular basis of the Keap1-Nrf2 system. Free Radic Biol Med. 88, 93-100 (2015).
    • (2015) Free Radic Biol Med , vol.88 , pp. 93-100
    • Suzuki, T.1    Yamamoto, M.2
  • 27
    • 84938765962 scopus 로고    scopus 로고
    • The Keap1/Nrf2 pathway in health and disease: From the bench to the clinic
    • O'Connell, M. A., Hayes, J. D. The Keap1/Nrf2 pathway in health and disease: from the bench to the clinic. Biochem Soc Trans 43, 687-689 (2015).
    • (2015) Biochem Soc Trans , vol.43 , pp. 687-689
    • O'Connell, M.A.1    Hayes, J.D.2
  • 28
    • 84938813629 scopus 로고    scopus 로고
    • Dissecting molecular cross-talk between Nrf2 and NF-? B response pathways
    • Wardyn, J. D., Ponsford, A. H., Sanderson, C. M. Dissecting molecular cross-talk between Nrf2 and NF-? B response pathways. Biochem Soc Trans 43, 621-626 (2015).
    • (2015) Biochem Soc Trans , vol.43 , pp. 621-626
    • Wardyn, J.D.1    Ponsford, A.H.2    Sanderson, C.M.3
  • 29
    • 0026577605 scopus 로고
    • A major inducer of anticarcinogenic protective enzymes from broccoli: Isolation and elucidation of structure
    • Zhang, Y., Talalay, P., Cho, C. G., Posner, G. H. A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure. Proc Natl Acad Sci USA 89, 2399-2403 (1992).
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 2399-2403
    • Zhang, Y.1    Talalay, P.2    Cho, C.G.3    Posner, G.H.4
  • 30
    • 0030931522 scopus 로고    scopus 로고
    • Broccoli sprouts: An exceptionally rich source of inducers of enzymes that protect against chemical carcinogens
    • Fahey, J. W., Zhang, Y., Talalay, P. Broccoli sprouts: an exceptionally rich source of inducers of enzymes that protect against chemical carcinogens. Proc Natl Acad Sci USA 94, 10367-10372 (1997).
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 10367-10372
    • Fahey, J.W.1    Zhang, Y.2    Talalay, P.3
  • 31
    • 84874489560 scopus 로고    scopus 로고
    • Keap1-Nrf2 signaling: A target for cancer prevention by sulforaphane
    • Kensler, T. W. et al. Keap1-Nrf2 signaling: a target for cancer prevention by sulforaphane. Top Curr Chem. 329, 163-177 (2013).
    • (2013) Top Curr Chem , vol.329 , pp. 163-177
    • Kensler, T.W.1
  • 32
    • 34247606510 scopus 로고    scopus 로고
    • Molecular basis for chemoprevention by sulforaphane: A comprehensive review
    • Juge, N., Mithen, R. F., Traka, M. Molecular basis for chemoprevention by sulforaphane: a comprehensive review. Cell Mol Life Sci. 64, 1105-1127 (2007).
    • (2007) Cell Mol Life Sci , vol.64 , pp. 1105-1127
    • Juge, N.1    Mithen, R.F.2    Traka, M.3
  • 33
    • 77649270763 scopus 로고    scopus 로고
    • Targeting NRF2 signaling for cancer chemoprevention
    • Kwak, M. K., Kensler, T. W. Targeting NRF2 signaling for cancer chemoprevention. Toxicol Appl Pharmacol 244, 66-76 (2010).
    • (2010) Toxicol Appl Pharmacol , vol.244 , pp. 66-76
    • Kwak, M.K.1    Kensler, T.W.2
  • 34
    • 84950241058 scopus 로고    scopus 로고
    • Sulforaphane bioavailability from glucoraphanin-rich broccoli: Control by active endogenous myrosinase
    • Fahey, J. W. et al. Sulforaphane bioavailability from glucoraphanin-rich broccoli: control by active endogenous myrosinase. PLos One 10, e0140963 (2015).
    • (2015) PLos One , vol.10 , pp. e0140963
    • Fahey, J.W.1
  • 35
    • 0037187646 scopus 로고    scopus 로고
    • Neurobiology of depression
    • Nestler, E. J. et al. Neurobiology of depression. Neuron 34, 13-25 (2002).
    • (2002) Neuron , vol.34 , pp. 13-25
    • Nestler, E.J.1
  • 36
    • 2442597374 scopus 로고    scopus 로고
    • Critical role of brain-derived neurotrophic factor in mood disorders
    • Hashimoto, K., Shimizu, E., Iyo, M. Critical role of brain-derived neurotrophic factor in mood disorders. Brain Res Brain Res Rev. 45, 104-114 (2004).
    • (2004) Brain Res Brain Res Rev , vol.45 , pp. 104-114
    • Hashimoto, K.1    Shimizu, E.2    Iyo, M.3
  • 37
    • 33745208951 scopus 로고    scopus 로고
    • A neutrotrophic model for stress-related mood disorders
    • Duman, R. S., Monteggia, L. M. A neutrotrophic model for stress-related mood disorders. Biol Psychiatry 59, 1116-1127 (2006).
    • (2006) Biol Psychiatry , vol.59 , pp. 1116-1127
    • Duman, R.S.1    Monteggia, L.M.2
  • 38
    • 77955078119 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor as a biomarker for mood disorders: An historical overview and future directions
    • Hashimoto, K. Brain-derived neurotrophic factor as a biomarker for mood disorders: an historical overview and future directions. Psychiatry Clin Neurosci 64, 341-357 (2010).
    • (2010) Psychiatry Clin Neurosci , vol.64 , pp. 341-357
    • Hashimoto, K.1
  • 39
    • 84870937818 scopus 로고    scopus 로고
    • Sigma-1 receptor chaperone and brain-derived neurotrophic factor: Emerging links between cardiovascular disease and depression
    • Hashimoto, K. Sigma-1 receptor chaperone and brain-derived neurotrophic factor: emerging links between cardiovascular disease and depression. Prog Neurobiol 100, 15-29 (2013).
    • (2013) Prog Neurobiol , vol.100 , pp. 15-29
    • Hashimoto, K.1
  • 40
    • 84906565721 scopus 로고    scopus 로고
    • Neurotrophins and psychiatric disorders
    • Castrén, E. Neurotrophins and psychiatric disorders. Handb Exp Pharmacol 220, 461-479 (2014).
    • (2014) Handb Exp Pharmacol , vol.220 , pp. 461-479
    • Castrén, E.1
  • 41
    • 84946781732 scopus 로고    scopus 로고
    • BDNF-A key transducer of antidepressant effects
    • Björkholm, C., Monteggia, L. M. BDNF-a key transducer of antidepressant effects. Neuropharmacology 102, 72-79 (2015).
    • (2015) Neuropharmacology , vol.102 , pp. 72-79
    • Björkholm, C.1    Monteggia, L.M.2
  • 42
    • 32444451651 scopus 로고    scopus 로고
    • Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress
    • Berton, O. et al. Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress. Science 311, 864-868 (2006).
    • (2006) Science , vol.311 , pp. 864-868
    • Berton, O.1
  • 43
    • 77249168715 scopus 로고    scopus 로고
    • A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone
    • Jang, S. W. et al. A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone. Proc Natl Acad Sci USA 107, 2687-2692 (2010).
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 2687-2692
    • Jang, S.W.1
  • 44
    • 84878261788 scopus 로고    scopus 로고
    • Effects of TrkB agonist 7,8-dihydroxyflavone on sensory gating deficits in mice after administration of methamphetamine
    • Ren, Q. et al. Effects of TrkB agonist 7,8-dihydroxyflavone on sensory gating deficits in mice after administration of methamphetamine. Pharmacol Biochem Behav 106, 124-127 (2013).
    • (2013) Pharmacol Biochem Behav , vol.106 , pp. 124-127
    • Ren, Q.1
  • 45
    • 84891830653 scopus 로고    scopus 로고
    • 7,8-Dihydroxyflavone, a TrkB agonist, attenuates behavioral abnormalities and neurotoxicity in mice after administration of methamphetamine
    • Ren, Q. et al. 7,8-Dihydroxyflavone, a TrkB agonist, attenuates behavioral abnormalities and neurotoxicity in mice after administration of methamphetamine. Psychopharmacology (Berl) 231, 159-166 (2014).
    • (2014) Psychopharmacology (Berl) 231 , pp. 159-166
    • Ren, Q.1
  • 46
    • 84989352639 scopus 로고    scopus 로고
    • BDNF-TrkB signaling in the nucleus accumbens shell of mice has key role in methamphetamine withdrawal symptoms
    • Ren, Q. et al. BDNF-TrkB signaling in the nucleus accumbens shell of mice has key role in methamphetamine withdrawal symptoms. Transl Psychiatry 5, e666 (2015).
    • (2015) Transl Psychiatry , vol.5 , pp. e666
    • Ren, Q.1
  • 47
    • 84927639238 scopus 로고    scopus 로고
    • Antidepressant effects of TrkB ligands on depression-like behavior and dendritic changes in mice after inflammation
    • Zhang, J. C. et al. Antidepressant effects of TrkB ligands on depression-like behavior and dendritic changes in mice after inflammation. Int J Neuropsychopharmacol 18, pii: pyu077 (2015).
    • (2015) Int J Neuropsychopharmacol , vol.18 , pp. 077
    • Zhang, J.C.1
  • 48
    • 84945469252 scopus 로고    scopus 로고
    • Comparison of ketamine, 7,8-dihydroxyflavone, and ANA-12 antidepressant effects in the social defeat stress model of depression
    • Zhang, J. C. et al. Comparison of ketamine, 7,8-dihydroxyflavone, and ANA-12 antidepressant effects in the social defeat stress model of depression. Psychopharmacology 232, 4325-4335 (2015).
    • (2015) Psychopharmacology , vol.232 , pp. 4325-4335
    • Zhang, J.C.1
  • 49
    • 79955489341 scopus 로고    scopus 로고
    • Identification of a low-molecular weight TrkB antagonist with anxiolytic and antidepressant activity in mice
    • Cazorla, M. et al. Identification of a low-molecular weight TrkB antagonist with anxiolytic and antidepressant activity in mice. J Clin Invest 121, 1846-1857 (2011).
    • (2011) J Clin Invest , vol.121 , pp. 1846-1857
    • Cazorla, M.1
  • 50
    • 84859996055 scopus 로고    scopus 로고
    • Protective effects of the antioxidant sulforaphane on behavioral changes and neurotoxicity in mice after the administration of methamphetamine
    • Chen, H. et al. Protective effects of the antioxidant sulforaphane on behavioral changes and neurotoxicity in mice after the administration of methamphetamine. Psychopharmacology (Berl) 222, 37-45 (2012).
    • (2012) Psychopharmacology (Berl) , vol.222 , pp. 37-45
    • Chen, H.1
  • 51
    • 84865811850 scopus 로고    scopus 로고
    • Effects of the antioxidant sulforaphane on hyperlocomotion and prepulse inhibition deficits in mice after phencyclidine administration
    • Shirai, Y., Fujita, Y., Hashimoto, K. Effects of the antioxidant sulforaphane on hyperlocomotion and prepulse inhibition deficits in mice after phencyclidine administration. Clin Psychopharmacol Neurosci 10, 97-98 (2012).
    • (2012) Clin Psychopharmacol Neurosci , vol.10 , pp. 97-98
    • Shirai, Y.1    Fujita, Y.2    Hashimoto, K.3
  • 52
    • 84939152891 scopus 로고    scopus 로고
    • Dietary intake of sulforaphane-rich broccoli sprout extracts during Juvenile and adolescence can prevent phencyclidine-induced cognitive deficits at adulthood
    • Shirai, Y. et al. Dietary intake of sulforaphane-rich broccoli sprout extracts during Juvenile and adolescence can prevent phencyclidine-induced cognitive deficits at adulthood. PLos One 10, e0127244 (2015).
    • (2015) PLos One , vol.10 , pp. e0127244
    • Shirai, Y.1
  • 53
    • 84884816644 scopus 로고    scopus 로고
    • Nrf2 deficiency leads to behavioral, neurochemical and transcriptional changes in mice
    • Muramatsu, H. et al. Nrf2 deficiency leads to behavioral, neurochemical and transcriptional changes in mice. Genes Cells 18, 899-908 (2013).
    • (2013) Genes Cells , vol.18 , pp. 899-908
    • Muramatsu, H.1
  • 54
    • 84979896709 scopus 로고    scopus 로고
    • Oxidative stress, anti-oxidants and the cross-sectional and longitudinal association with depressive symptoms: Results from the CARDIA study
    • Black, C. N. et al. Oxidative stress, anti-oxidants and the cross-sectional and longitudinal association with depressive symptoms: results from the CARDIA study. Transl Psychiatry 6, e743 (2016).
    • (2016) Transl Psychiatry , vol.6 , pp. e743
    • Black, C.N.1
  • 55
    • 84924330587 scopus 로고    scopus 로고
    • Oxidative stress as an etiological factor and a potential treatment target of psychiatric disorders Part 2. Depression, anxiety, schizophrenia and autism
    • Smaga, I. et al. Oxidative stress as an etiological factor and a potential treatment target of psychiatric disorders. Part 2. Depression, anxiety, schizophrenia and autism. Pharmacol Rep. 67, 569-580 (2015).
    • (2015) Pharmacol Rep , vol.67 , pp. 569-580
    • Smaga, I.1
  • 56
    • 0042154427 scopus 로고    scopus 로고
    • Altered gene expression of brain-derived neurotrophic factor and receptor tyrosin kinase B in postmortem brain of suicide subjects
    • Dwivedi, Y. et al. Altered gene expression of brain-derived neurotrophic factor and receptor tyrosin kinase B in postmortem brain of suicide subjects. Arch Gen Psychiatry 60, 804-815 (2003).
    • (2003) Arch Gen Psychiatry , vol.60 , pp. 804-815
    • Dwivedi, Y.1
  • 57
    • 18944406852 scopus 로고    scopus 로고
    • Neurotrophin levels in postmortem brains of suicide victims and the effects of antemortem diagnosis and psychotropic drugs
    • Karege, F. et al. Neurotrophin levels in postmortem brains of suicide victims and the effects of antemortem diagnosis and psychotropic drugs. Brain Res Mol Brain Res. 136, 29-37 (2005).
    • (2005) Brain Res Mol Brain Res , vol.136 , pp. 29-37
    • Karege, F.1
  • 58
    • 84929647417 scopus 로고    scopus 로고
    • Regional differences in brain-derived neurotrophic factor levels and dendritic spine density confer resilience to inescapable stress
    • Yang, C. et al. Regional differences in brain-derived neurotrophic factor levels and dendritic spine density confer resilience to inescapable stress. Int J Neuropsychopharmacol 18, pyu121 (2015).
    • (2015) Int J Neuropsychopharmacol , vol.18 , pp. 121
    • Yang, C.1
  • 59
    • 84940855007 scopus 로고    scopus 로고
    • R-Ketamine: A Rapid-Onset and sustained antidepressant without psychotomimetic side effects
    • Yang, C. et al. R-Ketamine: a rapid-onset and sustained antidepressant without psychotomimetic side effects. Transl Psychiatry 5, e632 (2015).
    • (2015) Transl Psychiatry , vol.5 , pp. e632
    • Yang, C.1
  • 60
    • 0037092425 scopus 로고    scopus 로고
    • Brain-Derived neurotrophic factor produces antidepressant effects in behavioral models of depression
    • Shirayama, Y. et al. Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression. J Neurosci. 22, 3251-3261 (2002).
    • (2002) J Neurosci , vol.22 , pp. 3251-3261
    • Shirayama, Y.1
  • 61
    • 84945448917 scopus 로고    scopus 로고
    • Alterations in brain-derived neurotrophic factor (BDNF) and its precursor proBDNF in the brain regions of a learned helplessness rat model and the antidepressant effects of a TrkB agonist and antagonist
    • Shirayama, Y. et al. Alterations in brain-derived neurotrophic factor (BDNF) and its precursor proBDNF in the brain regions of a learned helplessness rat model and the antidepressant effects of a TrkB agonist and antagonist. Eur Neuropsychopharmacol 25, 2449-2458 (2015).
    • (2015) Eur Neuropsychopharmacol , vol.25 , pp. 2449-2458
    • Shirayama, Y.1
  • 62
    • 3242666768 scopus 로고    scopus 로고
    • Essential role of brain-derived neurotrophic factor in adult hippocampal function
    • Monteggia, L. M. et al. Essential role of brain-derived neurotrophic factor in adult hippocampal function. Proc Natl Acad Sci USA 101, 10827-10832 (2004).
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 10827-10832
    • Monteggia, L.M.1
  • 63
    • 0037218768 scopus 로고    scopus 로고
    • Activation of the TrkB neurotrophin receptor is induced by antidepressant drugs and is required for antidepressant-induced behavioral effects
    • Saarelainen, T. et al. Activation of the TrkB neurotrophin receptor is induced by antidepressant drugs and is required for antidepressant-induced behavioral effects. J Neurosci. 23, 349-357 (2003).
    • (2003) J Neurosci , vol.23 , pp. 349-357
    • Saarelainen, T.1
  • 64
    • 33846105118 scopus 로고    scopus 로고
    • Brain-Derived neurotrophic factor conditional knockouts show gender differences in depression-related behaviors
    • Monteggia, L. M. et al. Brain-derived neurotrophic factor conditional knockouts show gender differences in depression-related behaviors. Biol Psychiatry 61, 187-197 (2007).
    • (2007) Biol Psychiatry , vol.61 , pp. 187-197
    • Monteggia, L.M.1
  • 65
    • 84883852983 scopus 로고    scopus 로고
    • Nrf2 participates in depressive disorders through an anti-inflammatory mechanism
    • Martín-de-Saavedra, M. D. et al. Nrf2 participates in depressive disorders through an anti-inflammatory mechanism. Psychoneuroendocrinology 38, 2010-2022 (2013).
    • (2013) Psychoneuroendocrinology , vol.38 , pp. 2010-2022
    • Martín-De-Saavedra, M.D.1
  • 66
    • 84929657641 scopus 로고    scopus 로고
    • Nrf2-signaling and BDNF: A new target for the antidepressant-like activity of chronic fluoxetine treatment in a mouse model of anxiety/depression
    • Mendez-David, I. et al. Nrf2-signaling and BDNF: A new target for the antidepressant-like activity of chronic fluoxetine treatment in a mouse model of anxiety/depression. Neurosci Lett. 597, 121-126 (2015).
    • (2015) Neurosci Lett , vol.597 , pp. 121-126
    • Mendez-David, I.1
  • 67
    • 65649152524 scopus 로고    scopus 로고
    • Associations of depression with C-reactive protein IL-1 and IL-6: A meta-analysis
    • Howren, M. B., Lamkin, D. M., Suls, J. Associations of depression with C-reactive protein, IL-1, and IL-6: a meta-analysis. Psychosom Med. 71, 171-186 (2009).
    • (2009) Psychosom Med , vol.71 , pp. 171-186
    • Howren, M.B.1    Lamkin, D.M.2    Suls, J.3
  • 68
    • 84943357496 scopus 로고    scopus 로고
    • Inflammation and clinical response to treatment in depression: A meta-analysis
    • Strawbridge, R. et al. Inflammation and clinical response to treatment in depression: A meta-analysis. Eur. Neuropsychopharmacol 25, 1532-1543 (2015).
    • (2015) Eur. Neuropsychopharmacol , vol.25 , pp. 1532-1543
    • Strawbridge, R.1
  • 69
    • 84908425948 scopus 로고    scopus 로고
    • Sulforaphane treatment of autism spectrum disorder (ASD)
    • Singh, K. et al. Sulforaphane treatment of autism spectrum disorder (ASD). Proc Natl Acad Sci USA 111, 15550-15555 (2014).
    • (2014) Proc Natl Acad Sci USA , vol.111 , pp. 15550-15555
    • Singh, K.1
  • 70
    • 84929455924 scopus 로고    scopus 로고
    • An open study of sulforaphane-rich broccoli sprout extract in patients with schizophrenia
    • Shiina, A. et al. An open study of sulforaphane-rich broccoli sprout extract in patients with schizophrenia. Clin Psychopharmacol Neurosci. 13, 62-67 (2015).
    • (2015) Clin Psychopharmacol Neurosci , vol.13 , pp. 62-67
    • Shiina, A.1
  • 71
    • 84928212338 scopus 로고    scopus 로고
    • Potentiation of neurite outgrowth by brexpiprazole, a novel serotonin-dopamine activity modulator: A role for serotonin 5-HT1A and 5-HT2A receptors
    • Ishima, T. et al. Potentiation of neurite outgrowth by brexpiprazole, a novel serotonin-dopamine activity modulator: a role for serotonin 5-HT1A and 5-HT2A receptors. Eur Neuropsychopharmacol 25, 505-511 (2015).
    • (2015) Eur Neuropsychopharmacol , vol.25 , pp. 505-511
    • Ishima, T.1
  • 72
    • 0031577292 scopus 로고    scopus 로고
    • An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements
    • Itoh, K. et al. An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements. Biochem Biophys Res Commun 236, 313-322 (1997).
    • (1997) Biochem Biophys Res Commun , vol.236 , pp. 313-322
    • Itoh, K.1
  • 73
    • 4644251008 scopus 로고    scopus 로고
    • Profiling glucosinolates, flavonoids, alkaloids, and other secondary metabolites in tissues of Azima tetracantha L. (Salvadoraceae)
    • Bennett, R. N. et al. Profiling glucosinolates, flavonoids, alkaloids, and other secondary metabolites in tissues of Azima tetracantha L. (Salvadoraceae). J Agric Food Chem. 52, 5856-5862 (2004).
    • (2004) J Agric Food Chem , vol.52 , pp. 5856-5862
    • Bennett, R.N.1
  • 74
    • 1242336781 scopus 로고    scopus 로고
    • Glucoraphanin and 4-hydroxyglucobrassicin contents in seeds of 59 cultivars of broccoli, raab, kohlrabi, radish, cauliflower, brussels sprouts, kale, and cabbage
    • West, L. G. et al. Glucoraphanin and 4-hydroxyglucobrassicin contents in seeds of 59 cultivars of broccoli, raab, kohlrabi, radish, cauliflower, brussels sprouts, kale, and cabbage. J Agric Food Chem. 52, 916-926 (2004).
    • (2004) J Agric Food Chem , vol.52 , pp. 916-926
    • West, L.G.1
  • 75
    • 80053589736 scopus 로고    scopus 로고
    • A standardized protocol for repeated social defeat stress in mice
    • Golden, S. A., Covington, H. E. 3rd., Berton, O., Russo, S. J. A standardized protocol for repeated social defeat stress in mice. Nat Protoc 6, 1183-1191 (2011).
    • (2011) Nat Protoc , vol.6 , pp. 1183-1191
    • Golden, S.A.1    Covington, H.E.2    Berton, O.3    Russo, S.J.4
  • 76
    • 84893713925 scopus 로고    scopus 로고
    • Stress and CRF gate neural activation of BDNF in the mesolimbic reward pathway
    • Walsh, J. J. et al. Stress and CRF gate neural activation of BDNF in the mesolimbic reward pathway. Nat Neurosci. 17, 27-29 (2014).
    • (2014) Nat Neurosci , vol.17 , pp. 27-29
    • Walsh, J.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.