Antidepressant effects of TrkB ligands on depression-like behavior and dendritic changes in mice after inflammation

International Journal of Neuropsychopharmacology

Volumn 18, Issue 4, 2014, Pages 1-12

  Zhang, Ji Chun ^a   Wu, Jin ^a   Fujita, Yuko ^a   Yao, Wei ^a   Ren, Qian ^a   Yang, Chun ^a   Li, Su Xia ^a,b   Shirayama, Yukihiko ^a,c   Hashimoto, Kenji ^a  

^a CHIBA UNIVERSITY   (Japan)

^b PEKING UNIVERSITY   (China)

^c TEIKYO UNIVERSITY CHIBA MEDICAL CENTER   (Japan)

Author keywords

BDNF TrkB signaling; Hippocampus; Inflammation; Nucleus accumbens; Prefrontal cortex

Indexed keywords

7,8 DIHYDROXYFLAVONE; AMIDE; BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; CHRYSIN; DEXAMETHASONE; LIPOPOLYSACCHARIDE; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N2 [2 [[(2 OXOAZEPAN 3 YL) AMINO]CARBONYL]PHENYL]BENZO[B]THIOPHENE 2 CARBOXAMIDE; PAROXETINE; PROTEIN TYROSINE KINASE INHIBITOR; RAPAMYCIN; UNCLASSIFIED DRUG; VENLAFAXINE; 6,7-DIHYDROXYFLAVONE; ANA 12 COMPOUND; ANTIDEPRESSANT AGENT; AZEPINE DERIVATIVE; BENZAMIDE DERIVATIVE; FLAVONE DERIVATIVE; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; TARGET OF RAPAMYCIN KINASE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDEPRESSANT ACTIVITY; ARTICLE; BRAIN REGION; CONTROLLED STUDY; DENDRITE; DENDRITIC SPINE; DENTATE GYRUS; DEPRESSION; HIPPOCAMPAL CA3 REGION; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; INFLAMMATION; MALE; MOUSE; NONHUMAN; NUCLEUS ACCUMBENS; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; AGONISTS; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; DEPRESSIVE DISORDER; DISEASE MODEL; DRUG EFFECTS; HIPPOCAMPUS; METABOLISM; PATHOPHYSIOLOGY; PHOSPHORYLATION; PHYSIOLOGY;

ANIMALS; ANTIDEPRESSIVE AGENTS; AZEPINES; BENZAMIDES; BRAIN-DERIVED NEUROTROPHIC FACTOR; DENDRITIC SPINES; DEPRESSIVE DISORDER; DISEASE MODELS, ANIMAL; FLAVONES; HIPPOCAMPUS; LIPOPOLYSACCHARIDES; MALE; MICE, INBRED C57BL; MULTIPROTEIN COMPLEXES; NUCLEUS ACCUMBENS; PHOSPHORYLATION; PREFRONTAL CORTEX; RECEPTOR, TRKB; TOR SERINE-THREONINE KINASES;

EID: 84927639238     PISSN: 14611457     EISSN: 14695111     Source Type: Journal    
DOI: 10.1093/ijnp/pyu077     Document Type: Article

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