-
1
-
-
35948946582
-
Use of treatment algorithms for depression
-
Trivedi M.H., Fava M., Marangell L.B., Osser D.N., Shelton R.C. Use of treatment algorithms for depression. Prim. Care Compan. J. Clin. Psychiatry 2006, 8:291-298.
-
(2006)
Prim. Care Compan. J. Clin. Psychiatry
, vol.8
, pp. 291-298
-
-
Trivedi, M.H.1
Fava, M.2
Marangell, L.B.3
Osser, D.N.4
Shelton, R.C.5
-
2
-
-
84867227874
-
Synaptic dysfunction in depression: potential therapeutic targets
-
Duman R.S., Aghajanian G.K. Synaptic dysfunction in depression: potential therapeutic targets. Science 2012, 338:68-72.
-
(2012)
Science
, vol.338
, pp. 68-72
-
-
Duman, R.S.1
Aghajanian, G.K.2
-
3
-
-
48049084135
-
The cytokine hypothesis of depression: inflammation, oxidative & nitrosative stress (IO&NS) and leaky gut as new targets for adjunctive treatments in depression
-
Maes M. The cytokine hypothesis of depression: inflammation, oxidative & nitrosative stress (IO&NS) and leaky gut as new targets for adjunctive treatments in depression. Neuro. Endocrinol. Lett. 2008, 29:287-291.
-
(2008)
Neuro. Endocrinol. Lett.
, vol.29
, pp. 287-291
-
-
Maes, M.1
-
4
-
-
47049121575
-
Inflammation, glutamate, and glia in depression: a literature review
-
McNally L., Bhagwagar Z., Hannestad J. Inflammation, glutamate, and glia in depression: a literature review. CNS Spectr. 2008, 13:501-510.
-
(2008)
CNS Spectr.
, vol.13
, pp. 501-510
-
-
McNally, L.1
Bhagwagar, Z.2
Hannestad, J.3
-
5
-
-
80052115992
-
Venlafaxine protects against stress-induced oxidative DNA damage in hippocampus during antidepressant testing in mice
-
Abdel-Wahab B.A., Salama R.H. Venlafaxine protects against stress-induced oxidative DNA damage in hippocampus during antidepressant testing in mice. Pharmacol. Biochem. Behav. 2011, 100:59-65.
-
(2011)
Pharmacol. Biochem. Behav.
, vol.100
, pp. 59-65
-
-
Abdel-Wahab, B.A.1
Salama, R.H.2
-
6
-
-
84862287737
-
Preclinical and clinical evidence of antioxidant effects of antidepressant agents: implications for the pathophysiology of major depressive disorder
-
Behr G.A., Moreira J.C., Frey B.N. Preclinical and clinical evidence of antioxidant effects of antidepressant agents: implications for the pathophysiology of major depressive disorder. Oxid. Med. Cell. Longev. 2012, 2012:609421.
-
(2012)
Oxid. Med. Cell. Longev.
, vol.2012
, pp. 609421
-
-
Behr, G.A.1
Moreira, J.C.2
Frey, B.N.3
-
7
-
-
84883554467
-
Oxidative/nitrosative stress and antidepressants: targets for novel antidepressants
-
Lee S.Y., Lee S.J., Han C., Patkar A.A., Masand P.S., Pae C.U. Oxidative/nitrosative stress and antidepressants: targets for novel antidepressants. Prog. Neuropsychopharmacol. Biol. Psychiatry 2013, 46:224-235.
-
(2013)
Prog. Neuropsychopharmacol. Biol. Psychiatry
, vol.46
, pp. 224-235
-
-
Lee, S.Y.1
Lee, S.J.2
Han, C.3
Patkar, A.A.4
Masand, P.S.5
Pae, C.U.6
-
8
-
-
84867034260
-
Role of nrf2 in oxidative stress and toxicity
-
Ma Q. Role of nrf2 in oxidative stress and toxicity. Annu. Rev. Pharmacol. Toxicol. 2013, 53:401-426.
-
(2013)
Annu. Rev. Pharmacol. Toxicol.
, vol.53
, pp. 401-426
-
-
Ma, Q.1
-
9
-
-
84883852983
-
Nrf2 participates in depressive disorders through an anti-inflammatory mechanism
-
Martin-de-Saavedra M.D., Budni J., Cunha M.P., Gomez-Rangel V., Lorrio S., Del Barrio L., Lastres-Becker I., Parada E., Tordera R.M., Rodrigues A.L., Cuadrado A., Lopez M.G. Nrf2 participates in depressive disorders through an anti-inflammatory mechanism. Psychoneuroendocrinology 2013, 38:2010-2022.
-
(2013)
Psychoneuroendocrinology
, vol.38
, pp. 2010-2022
-
-
Martin-de-Saavedra, M.D.1
Budni, J.2
Cunha, M.P.3
Gomez-Rangel, V.4
Lorrio, S.5
Del Barrio, L.6
Lastres-Becker, I.7
Parada, E.8
Tordera, R.M.9
Rodrigues, A.L.10
Cuadrado, A.11
Lopez, M.G.12
-
10
-
-
21744445077
-
Nrf2, a multi-organ protector?
-
Lee J.M., Li J., Johnson D.A., Stein T.D., Kraft A.D., Calkins M.J., Jakel R.J., Johnson J.A. Nrf2, a multi-organ protector?. FASEB J. 2005, 19:1061-1066.
-
(2005)
FASEB J.
, vol.19
, pp. 1061-1066
-
-
Lee, J.M.1
Li, J.2
Johnson, D.A.3
Stein, T.D.4
Kraft, A.D.5
Calkins, M.J.6
Jakel, R.J.7
Johnson, J.A.8
-
11
-
-
84865429068
-
Nrf2: a potential target for new therapeutics in liver disease
-
Bataille A.M., Manautou J.E. Nrf2: a potential target for new therapeutics in liver disease. Clin. Pharmacol. Ther. 2012, 92:340-348.
-
(2012)
Clin. Pharmacol. Ther.
, vol.92
, pp. 340-348
-
-
Bataille, A.M.1
Manautou, J.E.2
-
12
-
-
33744729373
-
Multiorgan autoimmune inflammation, enhanced lymphoproliferation, and impaired homeostasis of reactive oxygen species in mice lacking the antioxidant-activated transcription factor Nrf2
-
Ma Q., Battelli L., Hubbs A.F. Multiorgan autoimmune inflammation, enhanced lymphoproliferation, and impaired homeostasis of reactive oxygen species in mice lacking the antioxidant-activated transcription factor Nrf2. Am. J. Pathol. 2006, 168:1960-1974.
-
(2006)
Am. J. Pathol.
, vol.168
, pp. 1960-1974
-
-
Ma, Q.1
Battelli, L.2
Hubbs, A.F.3
-
13
-
-
34548500771
-
Quinone oxidoreductase (NQO1) gene polymorphism may not confer a susceptibility to mood disorders
-
Pae C.U., Yoon S.J., Patkar A.A., Kim J.J., Lee C., Paik I.H. Quinone oxidoreductase (NQO1) gene polymorphism may not confer a susceptibility to mood disorders. Psychiatry Res. 2007, 153:83-86.
-
(2007)
Psychiatry Res.
, vol.153
, pp. 83-86
-
-
Pae, C.U.1
Yoon, S.J.2
Patkar, A.A.3
Kim, J.J.4
Lee, C.5
Paik, I.H.6
-
14
-
-
79955909679
-
Glutamate cysteine ligase (GCL) and self reported depression: an association study from the HUNT
-
Berk M., Johansson S., Wray N.R., Williams L., Olsson C., Haavik J., Bjerkeset O. Glutamate cysteine ligase (GCL) and self reported depression: an association study from the HUNT. J. Affect. Disord. 2011, 131:207-213.
-
(2011)
J. Affect. Disord.
, vol.131
, pp. 207-213
-
-
Berk, M.1
Johansson, S.2
Wray, N.R.3
Williams, L.4
Olsson, C.5
Haavik, J.6
Bjerkeset, O.7
-
15
-
-
65649125633
-
Neurogenesis-dependent and -independent effects of fluoxetine in an animal model of anxiety/depression
-
David D.J., Samuels B.A., Rainer Q., Wang J.W., Marsteller D., Mendez I., Drew M., Craig D.A., Guiard B.P., Guilloux J.P., Artymyshyn R.P., Gardier A.M., Gerald C., Antonijevic I.A., Leonardo E.D., Hen R. Neurogenesis-dependent and -independent effects of fluoxetine in an animal model of anxiety/depression. Neuron 2009, 62:479-493.
-
(2009)
Neuron
, vol.62
, pp. 479-493
-
-
David, D.J.1
Samuels, B.A.2
Rainer, Q.3
Wang, J.W.4
Marsteller, D.5
Mendez, I.6
Drew, M.7
Craig, D.A.8
Guiard, B.P.9
Guilloux, J.P.10
Artymyshyn, R.P.11
Gardier, A.M.12
Gerald, C.13
Antonijevic, I.A.14
Leonardo, E.D.15
Hen, R.16
-
16
-
-
84900827276
-
Rapid anxiolytic effects of a 5-HT(4) receptor agonist are mediated by a neurogenesis-independent mechanism
-
Mendez-David I., David D.J., Darcet F., Wu M.V., Kerdine-Romer S., Gardier A.M., Hen R. Rapid anxiolytic effects of a 5-HT(4) receptor agonist are mediated by a neurogenesis-independent mechanism. Neuropsychopharmacology 2014, 39:1366-1378.
-
(2014)
Neuropsychopharmacology
, vol.39
, pp. 1366-1378
-
-
Mendez-David, I.1
David, D.J.2
Darcet, F.3
Wu, M.V.4
Kerdine-Romer, S.5
Gardier, A.M.6
Hen, R.7
-
17
-
-
84906565721
-
Neurotrophins and psychiatric disorders
-
Castren E. Neurotrophins and psychiatric disorders. Handb. Exp. Pharmacol. 2014, 220:461-479.
-
(2014)
Handb. Exp. Pharmacol.
, vol.220
, pp. 461-479
-
-
Castren, E.1
-
18
-
-
0031577292
-
An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements
-
Itoh K., Chiba T., Takahashi S., Ishii T., Igarashi K., Katoh Y., Oyake T., Hayashi N., Satoh K., Hatayama I., Yamamoto M., Nabeshima Y. An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements. Biochem. Biophys. Res. Commun. 1997, 236:313-322.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.236
, pp. 313-322
-
-
Itoh, K.1
Chiba, T.2
Takahashi, S.3
Ishii, T.4
Igarashi, K.5
Katoh, Y.6
Oyake, T.7
Hayashi, N.8
Satoh, K.9
Hatayama, I.10
Yamamoto, M.11
Nabeshima, Y.12
-
19
-
-
84856067756
-
Functional status of somatodendritic serotonin 1A autoreceptor after long-term treatment with fluoxetine in a mouse model of anxiety/depression based on repeated corticosterone administration
-
Rainer Q., Nguyen H.T., Quesseveur G., Gardier A.M., David D.J., Guiard B.P. Functional status of somatodendritic serotonin 1A autoreceptor after long-term treatment with fluoxetine in a mouse model of anxiety/depression based on repeated corticosterone administration. Mol. Pharmacol. 2012, 81:106-112.
-
(2012)
Mol. Pharmacol.
, vol.81
, pp. 106-112
-
-
Rainer, Q.1
Nguyen, H.T.2
Quesseveur, G.3
Gardier, A.M.4
David, D.J.5
Guiard, B.P.6
-
20
-
-
79953055982
-
Integrated behavioral z-scoring increases the sensitivity and reliability of behavioral phenotyping in mice: relevance to emotionality and sex
-
Guilloux J.P., Seney M., Edgar N., Sibille E. Integrated behavioral z-scoring increases the sensitivity and reliability of behavioral phenotyping in mice: relevance to emotionality and sex. J. Neurosci. Methods 2011, 197:21-31.
-
(2011)
J. Neurosci. Methods
, vol.197
, pp. 21-31
-
-
Guilloux, J.P.1
Seney, M.2
Edgar, N.3
Sibille, E.4
-
21
-
-
84885338313
-
A method for biomarker measurements in peripheral blood mononuclear cells isolated from anxious and depressed mice: beta-arrestin 1 protein levels in depression and treatment
-
Mendez-David I., El-Ali Z., Hen R., Falissard B., Corruble E., Gardier A.M., Kerdine-Romer S., David D.J. A method for biomarker measurements in peripheral blood mononuclear cells isolated from anxious and depressed mice: beta-arrestin 1 protein levels in depression and treatment. Front Pharmacol. 2013, 4:124.
-
(2013)
Front Pharmacol.
, vol.4
, pp. 124
-
-
Mendez-David, I.1
El-Ali, Z.2
Hen, R.3
Falissard, B.4
Corruble, E.5
Gardier, A.M.6
Kerdine-Romer, S.7
David, D.J.8
-
22
-
-
79954598830
-
Depression is an inflammatory disease, but cell-mediated immune activation is the key component of depression
-
Maes M. Depression is an inflammatory disease, but cell-mediated immune activation is the key component of depression. Prog. Neuropsychopharmacol. Biol. Psychiatry 2011, 35:664-675.
-
(2011)
Prog. Neuropsychopharmacol. Biol. Psychiatry
, vol.35
, pp. 664-675
-
-
Maes, M.1
-
23
-
-
82655172359
-
Activation of cell-mediated immunity in depression: association with inflammation, melancholia, clinical staging and the fatigue and somatic symptom cluster of depression
-
Maes M., Mihaylova I., Kubera M., Ringel K. Activation of cell-mediated immunity in depression: association with inflammation, melancholia, clinical staging and the fatigue and somatic symptom cluster of depression. Prog. Neuropsychopharmacol. Biol. Psychiatry 2012, 36:169-175.
-
(2012)
Prog. Neuropsychopharmacol. Biol. Psychiatry
, vol.36
, pp. 169-175
-
-
Maes, M.1
Mihaylova, I.2
Kubera, M.3
Ringel, K.4
-
24
-
-
47949083810
-
The transcription factor Nrf2 is a therapeutic target against brain inflammation
-
Innamorato N.G., Rojo A.I., Garcia-Yague A.J., Yamamoto M., de Ceballos M.L., Cuadrado A. The transcription factor Nrf2 is a therapeutic target against brain inflammation. J. Immunol. 2008, 181:680-689.
-
(2008)
J. Immunol.
, vol.181
, pp. 680-689
-
-
Innamorato, N.G.1
Rojo, A.I.2
Garcia-Yague, A.J.3
Yamamoto, M.4
de Ceballos, M.L.5
Cuadrado, A.6
-
25
-
-
84906605867
-
Lymphocyte levels of redox-sensitive transcription factors and antioxidative enzymes as indicators of pro-oxidative state in depressive patients
-
Lukic I., Mitic M., Djordjevic J., Tatalovic N., Bozovic N., Soldatovic I., Mihaljevic M., Pavlovic Z., Radojcic M.B., Maric N.P., Adzic M. Lymphocyte levels of redox-sensitive transcription factors and antioxidative enzymes as indicators of pro-oxidative state in depressive patients. Neuropsychobiology 2014, 70:1-9.
-
(2014)
Neuropsychobiology
, vol.70
, pp. 1-9
-
-
Lukic, I.1
Mitic, M.2
Djordjevic, J.3
Tatalovic, N.4
Bozovic, N.5
Soldatovic, I.6
Mihaljevic, M.7
Pavlovic, Z.8
Radojcic, M.B.9
Maric, N.P.10
Adzic, M.11
-
26
-
-
84862769027
-
New drug targets in depression: inflammatory, cell-mediated immune, oxidative and nitrosative stress, mitochondrial, antioxidant, and neuroprogressive pathways. And new drug candidates-Nrf2 activators and GSK-3 inhibitors
-
Maes M., Fisar Z., Medina M., Scapagnini G., Nowak G., Berk M. New drug targets in depression: inflammatory, cell-mediated immune, oxidative and nitrosative stress, mitochondrial, antioxidant, and neuroprogressive pathways. And new drug candidates-Nrf2 activators and GSK-3 inhibitors. Inflammopharmacology 2012, 20:127-150.
-
(2012)
Inflammopharmacology
, vol.20
, pp. 127-150
-
-
Maes, M.1
Fisar, Z.2
Medina, M.3
Scapagnini, G.4
Nowak, G.5
Berk, M.6
-
27
-
-
84929660426
-
Differential and converging molecular mechanisms of antidepressants' action in the hippocampal dentate gyrus
-
Patricio P., Mateus-Pinheiro A., Irmler M., Alves N.D., Machado-Santos A.R., Morais M., Correia J.S., Korostynski M., Piechota M., Stoffel R., Beckers J., Bessa J.M., Almeida O.F., Sousa N., Pinto L. Differential and converging molecular mechanisms of antidepressants' action in the hippocampal dentate gyrus. Neuropsychopharmacology 2015, 40:338-349.
-
(2015)
Neuropsychopharmacology
, vol.40
, pp. 338-349
-
-
Patricio, P.1
Mateus-Pinheiro, A.2
Irmler, M.3
Alves, N.D.4
Machado-Santos, A.R.5
Morais, M.6
Correia, J.S.7
Korostynski, M.8
Piechota, M.9
Stoffel, R.10
Beckers, J.11
Bessa, J.M.12
Almeida, O.F.13
Sousa, N.14
Pinto, L.15
-
28
-
-
33846924300
-
How many transcription factors does it take to turn on the heme oxygenase-1 gene?
-
Alam J., Cook J.L. How many transcription factors does it take to turn on the heme oxygenase-1 gene?. Am. J. Respir. Cell Mol. Biol. 2007, 36:166-174.
-
(2007)
Am. J. Respir. Cell Mol. Biol.
, vol.36
, pp. 166-174
-
-
Alam, J.1
Cook, J.L.2
-
29
-
-
1642396537
-
Role of Nrf2 in the regulation of CD36 and stress protein expression in murine macrophages: activation by oxidatively modified LDL and 4-hydroxynonenal
-
Ishii T., Itoh K., Ruiz E., Leake D.S., Unoki H., Yamamoto M., Mann G.E. Role of Nrf2 in the regulation of CD36 and stress protein expression in murine macrophages: activation by oxidatively modified LDL and 4-hydroxynonenal. Circ. Res. 2004, 94:609-616.
-
(2004)
Circ. Res.
, vol.94
, pp. 609-616
-
-
Ishii, T.1
Itoh, K.2
Ruiz, E.3
Leake, D.S.4
Unoki, H.5
Yamamoto, M.6
Mann, G.E.7
-
30
-
-
33646691510
-
Curcumin activates defensive genes and protects neurons against oxidative stress
-
Scapagnini G., Colombrita C., Amadio M., D'Agata V., Arcelli E., Sapienza M., Quattrone A., Calabrese V. Curcumin activates defensive genes and protects neurons against oxidative stress. Antioxid. Redox Signal. 2006, 8:395-403.
-
(2006)
Antioxid. Redox Signal.
, vol.8
, pp. 395-403
-
-
Scapagnini, G.1
Colombrita, C.2
Amadio, M.3
D'Agata, V.4
Arcelli, E.5
Sapienza, M.6
Quattrone, A.7
Calabrese, V.8
-
31
-
-
77955637265
-
Serum and plasma BDNF levels in major depression: a replication study and meta-analyses
-
Bocchio-Chiavetto L., Bagnardi V., Zanardini R., Molteni R., Nielsen M.G., Placentino A., Giovannini C., Rillosi L., Ventriglia M., Riva M.A., Gennarelli M. Serum and plasma BDNF levels in major depression: a replication study and meta-analyses. World J. Biol. Psychiatry 2010, 11:763-773.
-
(2010)
World J. Biol. Psychiatry
, vol.11
, pp. 763-773
-
-
Bocchio-Chiavetto, L.1
Bagnardi, V.2
Zanardini, R.3
Molteni, R.4
Nielsen, M.G.5
Placentino, A.6
Giovannini, C.7
Rillosi, L.8
Ventriglia, M.9
Riva, M.A.10
Gennarelli, M.11
-
32
-
-
84862990970
-
Plasma brain-derived neurotrophic factor levels predict the clinical outcome of depression treatment in a naturalistic study
-
Kurita M., Nishino S., Kato M., Numata Y., Sato T. Plasma brain-derived neurotrophic factor levels predict the clinical outcome of depression treatment in a naturalistic study. PLoS One 2012, 7:e39212.
-
(2012)
PLoS One
, vol.7
, pp. e39212
-
-
Kurita, M.1
Nishino, S.2
Kato, M.3
Numata, Y.4
Sato, T.5
-
33
-
-
84902578456
-
Nrf2 regulates neurogenesis and protects neural progenitor cells against Abeta toxicity
-
Karkkainen V., Pomeshchik Y., Savchenko E., Dhungana H., Kurronen A., Lehtonen S., Naumenko N., Tavi P., Levonen A.L., Yamamoto M., Malm T., Magga J., Kanninen K.M., Koistinaho J. Nrf2 regulates neurogenesis and protects neural progenitor cells against Abeta toxicity. Stem Cells 2014, 32:1904-1916.
-
(2014)
Stem Cells
, vol.32
, pp. 1904-1916
-
-
Karkkainen, V.1
Pomeshchik, Y.2
Savchenko, E.3
Dhungana, H.4
Kurronen, A.5
Lehtonen, S.6
Naumenko, N.7
Tavi, P.8
Levonen, A.L.9
Yamamoto, M.10
Malm, T.11
Magga, J.12
Kanninen, K.M.13
Koistinaho, J.14
-
34
-
-
84925884428
-
HO-1 attenuates hippocampal neurons injury via the activation of BDNF-TrkB-PI3K/Akt signaling pathway in stroke
-
Qi D., Ouyang C., Wang Y., Zhang S., Ma X., Song Y., Yu H., Tang J., Fu W., Sheng L., Yang L., Wang M., Zhang W., Miao L., Li T., Huang X., Dong H. HO-1 attenuates hippocampal neurons injury via the activation of BDNF-TrkB-PI3K/Akt signaling pathway in stroke. Brain Res. 2014, 1577:69-76.
-
(2014)
Brain Res.
, vol.1577
, pp. 69-76
-
-
Qi, D.1
Ouyang, C.2
Wang, Y.3
Zhang, S.4
Ma, X.5
Song, Y.6
Yu, H.7
Tang, J.8
Fu, W.9
Sheng, L.10
Yang, L.11
Wang, M.12
Zhang, W.13
Miao, L.14
Li, T.15
Huang, X.16
Dong, H.17
|