A single-molecule view of transcription reveals convoys of RNA polymerases and multi-scale bursting

Nature Communications

Volumn 7, Issue , 2016, Pages

  Tantale, Katjana ^a   Mueller, Florian ^b   Kozulic Pirher, Alja ^a   Lesne, Annick ^a,c   Victor, Jean Marc ^a,c   Robert, Marie Cecile ^a   Capozi, Serena ^a   Chouaib, Racha ^a   Bäcker, Volker ^d   Mateos Langerak, Julio ^d   Darzacq, Xavier ^e,f   Zimmer, Christophe ^b   Basyuk, Eugenia ^a   Bertrand, Edouard ^a  

^a INSTITUT DE GÉNÉTIQUE MOLÉCULAIRE DE MONTPELLIER   (France)

^b INSTITUT PASTEUR   (France)

^c SORBONNE UNIVERSITÉ   (France)

^d University of Montpellier   (France)

^e PSL RESEARCH UNIVERSITY   (France)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; NUCLEOTIDE; RNA POLYMERASE; VIRUS RNA; DNA DIRECTED RNA POLYMERASE; RNA; TATA BINDING PROTEIN; TRANSACTIVATOR PROTEIN;

CELLS AND CELL COMPONENTS; ENZYME ACTIVITY; GENE EXPRESSION; NUMERICAL MODEL; PHENOTYPE; RNA;

ARTICLE; CONTROLLED STUDY; HUMAN IMMUNODEFICIENCY VIRUS 1; MOLECULAR INTERACTION; PHENOTYPIC VARIATION; PROMOTER REGION; RNA SYNTHESIS; RNA TRANSCRIPTION; STOCHASTIC MODEL; TATA BOX; BIOLOGICAL MODEL; CELL SURVIVAL; GENETIC TRANSCRIPTION; GENETICS; HELA CELL LINE; HUMAN; KINETICS; METABOLISM; NUCLEOTIDE SEQUENCE; PROCEDURES; SINGLE MOLECULE IMAGING;

HUMAN IMMUNODEFICIENCY VIRUS 1;

BASE SEQUENCE; CELL SURVIVAL; DNA-DIRECTED RNA POLYMERASES; GENE PRODUCTS, TAT; HELA CELLS; HIV-1; HUMANS; KINETICS; MODELS, BIOLOGICAL; PROMOTER REGIONS, GENETIC; RNA; SINGLE MOLECULE IMAGING; TATA BOX; TATA-BOX BINDING PROTEIN; TRANSCRIPTION, GENETIC;

EID: 84979920522     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms12248     Document Type: Article

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