-
1
-
-
0027274981
-
The Caenorhabditis elegans unc-17 gene: A putative vesicular acetylcholine transporter
-
Alfonso, A., K. Grundahl, J. S. Duerr, H. P. Han, and J. B. Rand, 1993 The Caenorhabditis elegans unc-17 gene: a putative vesicular acetylcholine transporter. Science 261: 617–619.
-
(1993)
Science
, vol.261
, pp. 617-619
-
-
Alfonso, A.1
Grundahl, K.2
Duerr, J.S.3
Han, H.P.4
Rand, J.B.5
-
2
-
-
84964313213
-
Efficient marker-free recovery of custom genetic modifications with CRISPR/Cas9 in Caenorhabditis elegans
-
Arribere, J. A., R. T. Bell, B. X. Fu, K. L. Artiles, P. S. Hartman et al., 2014 Efficient marker-free recovery of custom genetic modifications with CRISPR/Cas9 in Caenorhabditis elegans. Genetics 198: 837–846.
-
(2014)
Genetics
, vol.198
, pp. 837-846
-
-
Arribere, J.A.1
Bell, R.T.2
Fu, B.X.3
Artiles, K.L.4
Hartman, P.S.5
-
3
-
-
84979934593
-
Cas9 variants expand the target repertoire in Caenorhabditis elegans
-
Bell, R. T., B. X. Fu, and A. Z. Fire, 2015 Cas9 variants expand the target repertoire in Caenorhabditis elegans. Genetics 202: 381–388.
-
(2015)
Genetics
, vol.202
, pp. 381-388
-
-
Bell, R.T.1
Fu, B.X.2
Fire, A.Z.3
-
4
-
-
0032185810
-
Localization of ASH1 mRNA particles in living yeast
-
Bertrand, E., P. Chartrand, M. Schaefer, S. M. Shenoy, R. H. Singer et al., 1998 Localization of ASH1 mRNA particles in living yeast. Mol. Cell 2: 437–445.
-
(1998)
Mol. Cell
, vol.2
, pp. 437-445
-
-
Bertrand, E.1
Chartrand, P.2
Schaefer, M.3
Shenoy, S.M.4
Singer, R.H.5
-
5
-
-
84884911076
-
Heritable gene knockout in Caenorhabditis elegans by direct injection of Cas9-sgRNA ribonucleoproteins
-
Cho, S. W., J. Lee, D. Carroll, J. S. Kim, and J. Lee, 2013 Heritable gene knockout in Caenorhabditis elegans by direct injection of Cas9-sgRNA ribonucleoproteins. Genetics 195: 1177–1180.
-
(2013)
Genetics
, vol.195
, pp. 1177-1180
-
-
Cho, S.W.1
Lee, J.2
Carroll, D.3
Kim, J.S.4
Lee, J.5
-
6
-
-
84873729095
-
Multiplex genome engineering using CRISPR/Cas systems
-
Cong, L., F. A. Ran, D. Cox, S. Lin, R. Barretto et al., 2013 Multiplex genome engineering using CRISPR/Cas systems. Science 339: 819–823.
-
(2013)
Science
, vol.339
, pp. 819-823
-
-
Cong, L.1
Ran, F.A.2
Cox, D.3
Lin, S.4
Barretto, R.5
-
7
-
-
41949138954
-
Gene activation using FLP recombinase in C. Elegans
-
Davis, M. W., J. J. Morton, D. Carroll, and E. M. Jorgensen, 2008 Gene activation using FLP recombinase in C. elegans. PLoS Genet. 4: e1000028.
-
(2008)
Plos Genet
, pp. 4
-
-
Davis, M.W.1
Morton, J.J.2
Carroll, D.3
Jorgensen, E.M.4
-
8
-
-
84884904381
-
Engineering the Caenorhabditis elegans genome using Cas9-triggered homologous recombination
-
Dickinson, D. J., J. D. Ward, D. J. Reiner, and B. Goldstein, 2013 Engineering the Caenorhabditis elegans genome using Cas9-triggered homologous recombination. Nat. Methods 10: 1028–1034.
-
(2013)
Nat. Methods
, vol.10
, pp. 1028-1034
-
-
Dickinson, D.J.1
Ward, J.D.2
Reiner, D.J.3
Goldstein, B.4
-
9
-
-
84939433336
-
Streamlined genome engineering with a self-excising drug selection cassette
-
Dickinson, D. J., A. M. Pani, J. K. Heppert, C. D. Higgins, and B. Goldstein, 2015 Streamlined genome engineering with a self-excising drug selection cassette. Genetics 200: 1035–1049.
-
(2015)
Genetics
, vol.200
, pp. 1035-1049
-
-
Dickinson, D.J.1
Pani, A.M.2
Heppert, J.K.3
Higgins, C.D.4
Goldstein, B.5
-
10
-
-
84913594397
-
Genome editing. The new frontier of genome engineering with CRISPR-Cas9
-
Doudna, J. A., and E. Charpentier, 2014 Genome editing. The new frontier of genome engineering with CRISPR-Cas9. Science 346: 1258096.
-
(2014)
Science
, vol.346
-
-
Doudna, J.A.1
Charpentier, E.2
-
11
-
-
65849183178
-
Golden gate shuffling: A one-pot DNA shuffling method based on type IIs restriction enzymes
-
Engler, C., R. Gruetzner, R. Kandzia, and S. Marillonnet, 2009 Golden gate shuffling: a one-pot DNA shuffling method based on type IIs restriction enzymes. PLoS One 4: e5553.
-
(2009)
Plos One
, pp. 4
-
-
Engler, C.1
Gruetzner, R.2
Kandzia, R.3
Marillonnet, S.4
-
12
-
-
84926433352
-
Dramatic enhancement of genome editing by CRISPR/Cas9 through improved guide RNA design
-
Farboud, B., and B. J. Meyer, 2015 Dramatic enhancement of genome editing by CRISPR/Cas9 through improved guide RNA design. Genetics 199: 959–971.
-
(2015)
Genetics
, vol.199
, pp. 959-971
-
-
Farboud, B.1
Meyer, B.J.2
-
13
-
-
84881475586
-
Heritable genome editing in C. Elegans via a CRISPR-Cas9 system
-
Friedland, A. E., Y. B. Tzur, K. M. Esvelt, M. P. Colaiacovo, G. M. Church et al., 2013 Heritable genome editing in C. elegans via a CRISPR-Cas9 system. Nat. Methods 10: 741–743.
-
(2013)
Nat. Methods
, vol.10
, pp. 741-743
-
-
Friedland, A.E.1
Tzur, Y.B.2
Esvelt, K.M.3
Colaiacovo, M.P.4
Church, G.M.5
-
14
-
-
84887109827
-
Exciting prospects for precise engineering of Caenorhabditis elegans genomes with CRISPR/Cas9
-
Frøkjær-Jensen, C., 2013 Exciting prospects for precise engineering of Caenorhabditis elegans genomes with CRISPR/Cas9. Genetics 195: 635–642.
-
(2013)
Genetics
, vol.195
, pp. 635-642
-
-
Frøkjær-Jensen, C.1
-
15
-
-
55049117864
-
Single-copy insertion of transgenes in Caenorhabditis elegans
-
Frøkjær-Jensen, C., M. W. Davis, C. E. Hopkins, B. J. Newman, J. M. Thummel et al., 2008 Single-copy insertion of transgenes in Caenorhabditis elegans. Nat. Genet. 40: 1375–1383.
-
(2008)
Nat. Genet
, vol.40
, pp. 1375-1383
-
-
Frøkjær-Jensen, C.1
Davis, M.W.2
Hopkins, C.E.3
Newman, B.J.4
Thummel, J.M.5
-
16
-
-
84856470784
-
Improved Mos1-mediated transgenesis in C. Elegans
-
Frøkjær-Jensen, C., M. W. Davis, M. Ailion, and E. M. Jorgensen, 2012 Improved Mos1-mediated transgenesis in C. elegans. Nat. Methods 9: 117–118.
-
(2012)
Nat. Methods
, vol.9
, pp. 117-118
-
-
Frøkjær-Jensen, C.1
Davis, M.W.2
Ailion, M.3
Jorgensen, E.M.4
-
17
-
-
84866859751
-
Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria
-
Gasiunas, G., R. Barrangou, P. Horvath, and V. Siksnys, 2012 Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria. Proc. Natl. Acad. Sci. USA 109: E2579–E2586.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. E2579-E2586
-
-
Gasiunas, G.1
Barrangou, R.2
Horvath, P.3
Siksnys, V.4
-
18
-
-
84941215703
-
Computer-assisted transgenesis of Caenorhabditis elegans for deep phenotyping
-
Gilleland, C. L., A. T. Falls, J. Noraky, M. G. Heiman, and M. F. Yanik, 2015 Computer-assisted transgenesis of Caenorhabditis elegans for deep phenotyping. Genetics 201: 39–46.
-
(2015)
Genetics
, vol.201
, pp. 39-46
-
-
Gilleland, C.L.1
Falls, A.T.2
Noraky, J.3
Heiman, M.G.4
Yanik, M.F.5
-
19
-
-
0024378286
-
The FLP recombinase of yeast catalyzes site-specific recombination in the Drosophila genome
-
Golic, K. G., and S. Lindquist, 1989 The FLP recombinase of yeast catalyzes site-specific recombination in the Drosophila genome. Cell 59: 499–509.
-
(1989)
Cell
, vol.59
, pp. 499-509
-
-
Golic, K.G.1
Lindquist, S.2
-
21
-
-
84865070369
-
A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity
-
Jinek, M., K. Chylinski, I. Fonfara, M. Hauer, J. A. Doudna et al., 2012 A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. Science 337: 816–821.
-
(2012)
Science
, vol.337
, pp. 816-821
-
-
Jinek, M.1
Chylinski, K.2
Fonfara, I.3
Hauer, M.4
Doudna, J.A.5
-
22
-
-
84876567971
-
RNA-programmed genome editing in human cells
-
Jinek, M., A. East, A. Cheng, S. Lin, E. Ma et al., 2013 RNA-programmed genome editing in human cells. eLife 2: e00471.
-
(2013)
Elife
, vol.2
-
-
Jinek, M.1
East, A.2
Cheng, A.3
Lin, S.4
Ma, E.5
-
23
-
-
84884943528
-
Targeted heritable mutation and gene conversion by Cas9-CRISPR in Caenorhabditis elegans
-
Katic, I., and H. Grosshans, 2013 Targeted heritable mutation and gene conversion by Cas9-CRISPR in Caenorhabditis elegans. Genetics 195: 1173–1176.
-
(2013)
Genetics
, vol.195
, pp. 1173-1176
-
-
Katic, I.1
Grosshans, H.2
-
24
-
-
84938894975
-
-
Katic, I., L. Xu, and R. Ciosk, 2015 CRISPR/Cas9 genome editing in Caenorhabditis elegans: evaluation of templates for homology-mediated repair and knock-ins by homology-independent DNA repair. G3 5: 1649–1656.
-
(2015)
Crispr/Cas9 Genome Editing in Caenorhabditis Elegans: Evaluation of Templates for Homology-Mediated Repair and Knock-Ins by Homology-Independent DNA Repair
, vol.G3
, Issue.5
, pp. 1649-1656
-
-
Katic, I.1
Xu, L.2
Ciosk, R.3
-
25
-
-
0037225952
-
A general method for the covalent labeling of fusion proteins with small molecules in vivo
-
Keppler, A., S. Gendreizig, T. Gronemeyer, H. Pick, H. Vogel et al., 2003 A general method for the covalent labeling of fusion proteins with small molecules in vivo. Nat. Biotechnol. 21: 86– 89.
-
(2003)
Nat. Biotechnol.
, vol.21
-
-
Keppler, A.1
Gendreizig, S.2
Gronemeyer, T.3
Pick, H.4
Vogel, H.5
-
26
-
-
84905665662
-
A co-CRISPR strategy for efficient genome editing in Caenorhabditis elegans
-
Kim, H., T. Ishidate, K. S. Ghanta, M. Seth, D. Conte, Jr. et al., 2014 A co-CRISPR strategy for efficient genome editing in Caenorhabditis elegans. Genetics 197: 1069–1080.
-
(2014)
Genetics
, vol.197
, pp. 1069-1080
-
-
Kim, H.1
Ishidate, T.2
Ghanta, K.S.3
Seth, M.4
Conte, D.5
-
27
-
-
84937908208
-
Engineered CRISPR-Cas9 nucleases with altered PAM specificities
-
Kleinstiver, B. P., M. S. Prew, S. Q. Tsai, V. V. Topkar, N. T. Nguyen et al., 2015 Engineered CRISPR-Cas9 nucleases with altered PAM specificities. Nature 523: 481–485.
-
(2015)
Nature
, vol.523
, pp. 481-485
-
-
Kleinstiver, B.P.1
Prew, M.S.2
Tsai, S.Q.3
Topkar, V.V.4
Nguyen, N.T.5
-
28
-
-
69949115558
-
An overview of nested genes in eukaryotic genomes
-
Kumar, A., 2009 An overview of nested genes in eukaryotic genomes. Eukaryot. Cell 8: 1321–1329.
-
(2009)
Eukaryot. Cell
, vol.8
, pp. 1321-1329
-
-
Kumar, A.1
-
29
-
-
0026468322
-
Conservation of gene organization and trans-splicing in the glyceraldehyde-3-phosphate dehydrogenase-encoding genes of Caenorhabditis briggsae
-
Lee, Y. H., X. Y. Huang, D. Hirsh, G. E. Fox, and R. M. Hecht, 1992 Conservation of gene organization and trans-splicing in the glyceraldehyde-3-phosphate dehydrogenase-encoding genes of Caenorhabditis briggsae. Gene 121: 227–235.
-
(1992)
Gene
, vol.121
, pp. 227-235
-
-
Lee, Y.H.1
Huang, X.Y.2
Hirsh, D.3
Fox, G.E.4
Hecht, R.M.5
-
30
-
-
0032567339
-
Generation of destabilized green fluorescent protein as a transcription reporter
-
Li, X., X. Zhao, Y. Fang, X. Jiang, T. Duong et al., 1998 Generation of destabilized green fluorescent protein as a transcription reporter. J. Biol. Chem. 273: 34970–34975.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 34970-34975
-
-
Li, X.1
Zhao, X.2
Fang, Y.3
Jiang, X.4
Duong, T.5
-
31
-
-
84884922656
-
Precise and heritable genome editing in evolutionarily diverse nematodes using TALENs and CRISPR/Cas9 to engineer insertions and deletions
-
Lo, T. W., C. S. Pickle, S. Lin, E. J. Ralston, M. Gurling et al., 2013 Precise and heritable genome editing in evolutionarily diverse nematodes using TALENs and CRISPR/Cas9 to engineer insertions and deletions. Genetics 195: 331–348.
-
(2013)
Genetics
, vol.195
, pp. 331-348
-
-
Lo, T.W.1
Pickle, C.S.2
Lin, S.3
Ralston, E.J.4
Gurling, M.5
-
32
-
-
34447272975
-
The HaloTag: A novel technology for cell imaging and protein analysis
-
Los, G. V., and K. Wood, 2007 The HaloTag: a novel technology for cell imaging and protein analysis. Methods Mol. Biol. 356: 195–208.
-
(2007)
Methods Mol. Biol
, vol.356
, pp. 195-208
-
-
Los, G.V.1
Wood, K.2
-
33
-
-
84873734105
-
RNA-guided human genome engineering via Cas9
-
Mali, P., L. Yang, K. M. Esvelt, J. Aach, M. Guell et al., 2013 RNA-guided human genome engineering via Cas9. Science 339: 823–826.
-
(2013)
Science
, vol.339
, pp. 823-826
-
-
Mali, P.1
Yang, L.2
Esvelt, K.M.3
Aach, J.4
Guell, M.5
-
34
-
-
0030734546
-
Identification and characterization of the vesicular GABA transporter
-
McIntire, S. L., R. J. Reimer, K. Schuske, R. H. Edwards, and E. M. Jorgensen, 1997 Identification and characterization of the vesicular GABA transporter. Nature 389: 870–876.
-
(1997)
Nature
, vol.389
, pp. 870-876
-
-
McIntire, S.L.1
Reimer, R.J.2
Schuske, K.3
Edwards, R.H.4
Jorgensen, E.M.5
-
35
-
-
80052157467
-
Multiple new site-specific recombinases for use in manipulating animal genomes
-
Nern, A., B. D. Pfeiffer, K. Svoboda, and G. M. Rubin, 2011 Multiple new site-specific recombinases for use in manipulating animal genomes. Proc. Natl. Acad. Sci. USA 108: 14198–14203.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 14198-14203
-
-
Nern, A.1
Pfeiffer, B.D.2
Svoboda, K.3
Rubin, G.M.4
-
36
-
-
84943592701
-
Efficient genome editing in Caenorhabditis elegans with a toolkit of dual marker selection cassettes
-
Norris, A. D., H. M. Kim, M. P. Colaiacovo, and J. A. Calarco, 2015 Efficient genome editing in Caenorhabditis elegans with a toolkit of dual marker selection cassettes. Genetics 201: 449–458.
-
(2015)
Genetics
, vol.201
, pp. 449-458
-
-
Norris, A.D.1
Kim, H.M.2
Colaiacovo, M.P.3
Calarco, J.A.4
-
37
-
-
84915746762
-
Scalable and versatile genome editing using linear DNAs with microhomology to Cas9 sites in Caenorhabditis elegans
-
Paix, A., Y. Wang, H. E. Smith, C. Y. Lee, D. Calidas et al., 2014 Scalable and versatile genome editing using linear DNAs with microhomology to Cas9 sites in Caenorhabditis elegans. Genetics 198: 1347–1356.
-
(2014)
Genetics
, vol.198
, pp. 1347-1356
-
-
Paix, A.1
Wang, Y.2
Smith, H.E.3
Lee, C.Y.4
Calidas, D.5
-
38
-
-
84941248689
-
High efficiency, homology-directed genome editing in Caenorhabditis elegans using CRISPR-Cas9 ribonucleoprotein complexes
-
Paix, A., A. Folkmann, D. Rasoloson, and G. Seydoux, 2015 High efficiency, homology-directed genome editing in Caenorhabditis elegans using CRISPR-Cas9 ribonucleoprotein complexes. Genetics 201: 47–54.
-
(2015)
Genetics
, vol.201
, pp. 47-54
-
-
Paix, A.1
Folkmann, A.2
Rasoloson, D.3
Seydoux, G.4
-
39
-
-
0035853677
-
The Caenorhabditis elegans unc-32 gene encodes alternative forms of a vacuolar ATPase a subunit
-
Pujol, N., C. Bonnerot, J. J. Ewbank, Y. Kohara, and D. Thierry- Mieg, 2001 The Caenorhabditis elegans unc-32 gene encodes alternative forms of a vacuolar ATPase a subunit. J. Biol. Chem. 276: 11913–11921.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 11913-11921
-
-
Pujol, N.1
Bonnerot, C.2
Ewbank, J.J.3
Kohara, Y.4
Thierry-Mieg, D.5
-
40
-
-
84910067176
-
Chemical biology strategies for posttranslational control of protein function
-
Rakhit, R., R. Navarro, and T. J. Wandless, 2014 Chemical biology strategies for posttranslational control of protein function. Chem. Biol. 21: 1238–1252.
-
(2014)
Chem. Biol
, vol.21
, pp. 1238-1252
-
-
Rakhit, R.1
Navarro, R.2
Wandless, T.J.3
-
41
-
-
84874956967
-
Proteomic mapping of mitochondria in living cells via spatially restricted enzymatic tagging
-
Rhee, H. W., P. Zou, N. D. Udeshi, J. D. Martell, V. K. Mootha et al., 2013 Proteomic mapping of mitochondria in living cells via spatially restricted enzymatic tagging. Science 339: 1328–1331.
-
(2013)
Science
, vol.339
, pp. 1328-1331
-
-
Rhee, H.W.1
Zou, P.2
Udeshi, N.D.3
Martell, J.D.4
Mootha, V.K.5
-
42
-
-
84860270506
-
A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells
-
Roux, K. J., D. I. Kim, M. Raida, and B. Burke, 2012 A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells. J. Cell Biol. 196: 801–810.
-
(2012)
J. Cell Biol
, vol.196
, pp. 801-810
-
-
Roux, K.J.1
Kim, D.I.2
Raida, M.3
Burke, B.4
-
43
-
-
84939559736
-
Regulatory logic of pan-neuronal gene expression in C. Elegans
-
Stefanakis, N., I. Carrera, and O. Hobert, 2015 Regulatory logic of pan-neuronal gene expression in C. elegans. Neuron 87: 733– 750.
-
(2015)
Neuron
, vol.87
-
-
Stefanakis, N.1
Carrera, I.2
Hobert, O.3
-
44
-
-
0342680006
-
Food and metabolic signalling defects in a Caenorhabditis elegans serotonin-synthesis mutant
-
Sze, J. Y., M. Victor, C. Loer, Y. Shi, and G. Ruvkun, 2000 Food and metabolic signalling defects in a Caenorhabditis elegans serotonin-synthesis mutant. Nature 403: 560–564.
-
(2000)
Nature
, vol.403
, pp. 560-564
-
-
Sze, J.Y.1
Victor, M.2
Loer, C.3
Shi, Y.4
Ruvkun, G.5
-
45
-
-
84884968656
-
Heritable custom genomic modifications in Caenorhabditis elegans via a CRISPR-Cas9 system
-
Tzur, Y. B., A. E. Friedland, S. Nadarajan, G. M. Church, J. A. Calarco et al., 2013 Heritable custom genomic modifications in Caenorhabditis elegans via a CRISPR-Cas9 system. Genetics 195: 1181–1185.
-
(2013)
Genetics
, vol.195
, pp. 1181-1185
-
-
Tzur, Y.B.1
Friedland, A.E.2
Nadarajan, S.3
Church, G.M.4
Calarco, J.A.5
-
46
-
-
84935856905
-
Polymerase Theta is a key driver of genome evolution and of CRISPR/Cas9-mediated mutagenesis
-
van Schendel, R., S. F. Roerink, V. Portegijs, S. van den Heuvel, and M. Tijsterman, 2015 Polymerase Theta is a key driver of genome evolution and of CRISPR/Cas9-mediated mutagenesis. Nat. Commun. 6: 7394.
-
(2015)
Nat. Commun
, vol.6
, pp. 7394
-
-
Van Schendel, R.1
Roerink, S.F.2
Portegijs, V.3
Van Den Heuvel, S.4
Tijsterman, M.5
-
47
-
-
84926451490
-
Rapid and precise engineering of the Caenorhabditis elegans genome with lethal mutation co-conversion and inactivation of NHEJ repair
-
Ward, J. D., 2015 Rapid and precise engineering of the Caenorhabditis elegans genome with lethal mutation co-conversion and inactivation of NHEJ repair. Genetics 199: 363–377.
-
(2015)
Genetics
, vol.199
, pp. 363-377
-
-
Ward, J.D.1
-
48
-
-
84940588446
-
The application of CRISPR-Cas9 genome editing in Caenorhabditis elegans
-
Xu, S., 2015 The application of CRISPR-Cas9 genome editing in Caenorhabditis elegans. J. Genet. Genomics 42: 413–421.
-
(2015)
J. Genet. Genomics
, vol.42
, pp. 413-421
-
-
Xu, S.1
|