Scalable and versatile genome editing using linear DNAs with microhomology to Cas9 sites in Caenorhabditis elegans

Genetics

Volumn 198, Issue 4, 2014, Pages 1347-1356

  Paix, Alexandre ^a   Wang, Yuemeng ^a   Smith, Harold E ^b   Lee, Chih Yung S ^a   Calidas, Deepika ^a   Lu, Tu ^a   Smith, Jarrett ^a   Schmidt, Helen ^a   Krause, Michael W ^b   Seydoux, Geraldine ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRISPR ASSOCIATED PROTEIN; CRISPR ASSOCIATED PROTEIN 9; DNA; PROTEIN TAG; UNCLASSIFIED DRUG; OLIGONUCLEOTIDE; STOP CODON;

ADULT; ANIMAL CELL; ARTICLE; BACTERIAL GENOME; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; DNA END JOINING REPAIR; DNA INTEGRATION; DNA MODIFICATION; DNA REPAIR; DNA TEMPLATE; DOUBLE STRANDED DNA BREAK; EMBRYO; GENE DELETION; GENE INSERTION; GENE MUTATION; GENE SEQUENCE; GENETIC ENGINEERING; GENETIC SELECTION; GENETIC VARIABILITY; GENOME; HERMAPHRODITE; HOMOLOGY DIRECTED REPAIR; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN TARGETING; RESTRICTION SITE; START CODON; STOP CODON; YOUNG ADULT; ANIMAL; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE TARGETING; GENETICS; HOMOLOGOUS RECOMBINATION; METABOLISM; PROCEDURES; RECOMBINATION REPAIR; REPORTER GENE;

CAENORHABDITIS ELEGANS;

ANIMALS; CAENORHABDITIS ELEGANS; CODON, TERMINATOR; CRISPR-ASSOCIATED PROTEINS; DNA BREAKS, DOUBLE-STRANDED; GENE DELETION; GENE EXPRESSION; GENE TARGETING; GENES, REPORTER; GENOME; HOMOLOGOUS RECOMBINATION; MUTAGENESIS, INSERTIONAL; OLIGONUCLEOTIDES; RECOMBINATIONAL DNA REPAIR;

EID: 84915746762     PISSN: 00166731     EISSN: 19432631     Source Type: Journal    
DOI: 10.1534/genetics.114.170423     Document Type: Article

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