Hsp90 and PKM2 drive the expression of aromatase in Li-Fraumeni syndrome breast adipose stromal cells

Journal of Biological Chemistry

Volumn 291, Issue 31, 2016, Pages 16011-16023

  Subbaramaiah, Kotha ^a   Brown, Kristy A ^b,c   Zahid, Heba ^b,c,d   Balmus, Gabriel ^e,g   Weiss, Robert S ^e   Herbert, Brittney Shea ^f   Dannenberg, Andrew J ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

^c MONASH UNIVERSITY   (Australia)

^d TAIBAH UNIVERSITY   (Saudi Arabia)

^e Cornell University ^*  (United States)

^f INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CYTOLOGY; TISSUE;

AROMATASE EXPRESSIONS; ATP-ASE ACTIVITY; BREAST CANCER; BREAST TISSUES; ELEVATED LEVEL; HORMONE RECEPTORS; MAMMARY GLAND; RATE-LIMITING ENZYMES;

CELLS;

ACTIVATOR OF HEAT SHOCK PROTEIN 90 ADENOSINE TRIPHOSPHATASE 1; ADENOSINE TRIPHOSPHATASE; AROMATASE; HEAT SHOCK PROTEIN 90; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PROTEIN P53; PYRUVATE KINASE; PYRUVATE KINASE M2; UNCLASSIFIED DRUG; AHSA1 PROTEIN, HUMAN; AHSA1 PROTEIN, MOUSE; CARRIER PROTEIN; CHAPERONE; CYP19A1 PROTEIN, HUMAN; MEMBRANE PROTEIN; THYROID HORMONE; THYROID HORMONE-BINDING PROTEINS; TUMOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; FAMILIAL CANCER; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; MAMMARY GLAND; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; STROMA CELL; ADIPOSE TISSUE; ANIMAL; BIOSYNTHESIS; BREAST; CELL LINE; GENE EXPRESSION REGULATION; GENETICS; KNOCKOUT MOUSE; LI-FRAUMENI SYNDROME; METABOLISM; PATHOLOGY; UDDER;

ADIPOSE TISSUE; ANIMALS; AROMATASE; BREAST; CARRIER PROTEINS; CELL LINE; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HSP90 HEAT-SHOCK PROTEINS; HUMANS; LI-FRAUMENI SYNDROME; MAMMARY GLANDS, ANIMAL; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; MOLECULAR CHAPERONES; NEOPLASM PROTEINS; STROMAL CELLS; THYROID HORMONES;

EID: 84979783849     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.698902     Document Type: Article

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