HDAC6 modulates Hsp90 chaperone activity and regulates activation of aryl hydrocarbon receptor signaling

Journal of Biological Chemistry

Volumn 284, Issue 12, 2009, Pages 7436-7445

  Kekatpure, Vikram D ^a,b   Dannenberg, Andrew J ^a   Subbaramaiah, Kotha ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

, INHIBITOR; ARYL HYDROCARBON RECEPTOR; BASIC HELIX LOOP HELIXES; BROAD SPECTRUM; CHAPERONE ACTIVITY; COMPLEX FORMATIONS; CYTOSOL; ENVIRONMENTAL TOXINS; HDAC INHIBITORS; HYDROXAMIC ACIDS; HYPERACETYLATION; IN-CELL; MOLECULAR CHAPERONES; MUTATION ANALYSIS; PHARMACOLOGICAL INHIBITORS; POLYCHLORINATED DIOXINS; TETRACHLORODIBENZO P DIOXINS; TOXICOLOGICAL RESPONSE; TRICHOSTATIN A; XENOBIOTIC METABOLISM;

ACETYLATION; BIOCHEMISTRY; CELL CULTURE; HYDROCARBONS; LIGANDS; METABOLISM; ORGANIC ACIDS; SIGNALING; TRANSCRIPTION; TRANSCRIPTION FACTORS;

BIOACTIVITY;

AROMATIC HYDROCARBON RECEPTOR; CHAPERONE; CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; DIOXIN; HEAT SHOCK PROTEIN 90; HISTONE DEACETYLASE 6; POLYCYCLIC AROMATIC HYDROCARBON; PROTEIN P23; PROTEIN XAP 2; TRICHOSTATIN A; UNCLASSIFIED DRUG; VORINOSTAT; ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN; ARYL HYDROCARBON RECEPTOR-INTERACTING PROTEIN; CYP1B1 PROTEIN, HUMAN; CYTOCHROME P450; ENZYME INHIBITOR; HDAC6 PROTEIN, HUMAN; HISTONE DEACETYLASE; HYDROXAMIC ACID; ISOMERASE; PROSTAGLANDIN E SYNTHASE; SIGNAL PEPTIDE;

ACETYLATION; ARTICLE; CANCER CELL CULTURE; CELL NUCLEUS; COMPLEX FORMATION; CONTROLLED STUDY; CYTOSOL; ENZYME INACTIVATION; ENZYME INDUCTION; ENZYME REGULATION; GENE EXPRESSION REGULATION; GENE INACTIVATION; GENE SILENCING; HUMAN; HUMAN CELL; LIGAND BINDING; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RECEPTOR OCCUPANCY; SIGNAL TRANSDUCTION; XENOBIOTIC METABOLISM; BIOSYNTHESIS; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; ENZYME ACTIVATION; GENETICS; METABOLISM; MUTATION; POLLUTANT; TUMOR CELL LINE;

ACETYLATION; CELL LINE, TUMOR; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 ENZYME SYSTEM; DIOXINS; ENVIRONMENTAL POLLUTANTS; ENZYME ACTIVATION; ENZYME INHIBITORS; HISTONE DEACETYLASES; HSP90 HEAT-SHOCK PROTEINS; HUMANS; HYDROXAMIC ACIDS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; INTRAMOLECULAR OXIDOREDUCTASES; MUTATION; POLYCYCLIC HYDROCARBONS, AROMATIC; RECEPTORS, ARYL HYDROCARBON; SIGNAL TRANSDUCTION;

EID: 65549166880     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M808999200     Document Type: Article

References (50)

1. Gu, Y. Z., Hogenesch, J. B., and Bradfield, C. A. (2000) Annu. Rev. Pharmacol. Toxicol. 40, 519-561
2. Poland, A., Glover, E., and Kende, A. S. (1976) J. Biol. Chem. 251, 4936-4946
3. Bock, K. W., and Köhle, C. (2006) Biochem. Pharmacol. 72, 393-404
4. Andersson, P., McGuire, J., Rubio, C., Gradin, K., Whitelaw, M. L., Pettersson, S., Hanberg, A., and Poellinger, L. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 9990-9995
5. Moennikes, O., Loeppen, S., Buchmann, A., Andersson, P., Ittrich, C., Poellinger, L., and Schwarz, M. (2004) Cancer Res. 64, 4707-4710
6. Shimizu, Y., Nakatsuru, Y., Ichinose, M., Takahashi, Y., Kume, H., Mimura, J., Fujii-Kuriyama, Y., and Ishikawa, T. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 779-782
7. Denis, M., Cuthill, S., Wikström, A. C., Poellinger, L., and Gustafsson, J. A. (1988) Biochem. Biophys. Res. Commun. 155, 801-807
8. Perdew, G. H. (1988) J. Biol. Chem. 263, 13802-13805
9. Cox, M. B., and Miller, C. A. (2004) Cell Stress Chaperones 9, 4-20
10. Kazlauskas, A., Poellinger, L., and Pongratz, I. (1999) J. Biol. Chem. 274, 13519-13524
11. Meyer, B. K., Pray-Grant, M. G., Vanden Heuvel, J. P., and Perdew, G. H. (1988) Mol. Cell. Biol. 18, 978-988
12. Pongratz, I., Mason, G. G., and Poellinger, L. (1992) J. Biol. Chem. 267, 13728-13734
13. Whitelaw, M., Pongratz, I., Wilhelmsson, A., Gustafsson, J. A., and Poellinger, L. (1993) Mol. Cell. Biol. 13, 2504-2514
14. Probst, M. R., Reisz-Porszasz, S., Agbunag, R. V., Ong, M. S., and Hankinson, O. (1993) Mol. Pharmacol. 44, 511-518
15. Shehin, S. E., Stephenson, R. O., and Greenlee, W. F. (2000) J. Biol. Chem. 275, 6770-6776
16. Port, J. L., Yamaguchi, K., Du, B., De Lorenzo, M., Chang, M., Heerdt, P. M., Kopelovich, L., Marcus, C. B., Altorki, N. K., Subbaramaiah, K., and Dannenberg, A. J. (2004) Carcinogenesis 25, 2275-2281
17. Kawajiri, K., and Fujii-Kuriyama, Y. (2007) Arch. Biochem. Biophys. 464, 207-212
18. Shimada, T., Hayes, C. L., Yamazaki, H., Amin, S., Hecht, S. S., Guengerich, F. P., and Sutter, T. R. (1996) Cancer Res. 56, 2979-2984
19. Shimada, T., Oda, Y., Gillam, E. M., Guengerich, F. P., and Inoue, K. (2001) Drug Metab. Dispos. 29, 1176-1182
20. Harrigan, J. A., Vezina, C. M., McGarrigle, B. P., Ersing, N., Box, H. C., Maccubbin, A. E., and Olson, J. R. (2004) Toxicol. Sci. 77, 307-314
21. Hunt, S. N., Jusko, W. J., and Yurchak, A. M. (1976) Clin. Pharmacol. Ther. 19, 546-551
22. Hamilton, M., Wolf, J. L., Rusk, J., Beard, S. E., Clark, G. M., Witt, K., and Cagnoni, P. J. (2006) Clin. Cancer Res. 12, 2166-2171
23. Dertinger, S. D., Nazarenko, D. A., Silverstone, A. E., and Gasiewicz, T. A. (2001) Carcinogenesis 22, 171-177
24. Puppala, D., Lee, H., Kim, K. B., and Swanson, H. I. (2008) Mol. Pharmacol. 73, 1064-1071
25. Yu, X., Guo, Z. S., Marcu, M. G., Neckers, L., Nguyen, D. M., Chen, G. A., and Schrump, D. S. (2002) J. Natl. Cancer Inst. 94, 504-513
26. Fiskus, W., Ren, Y., Mohapatra, A., Bali, P., Mandawat, A., Rao, R., Herger, B., Yang, Y., Atadja, P., Wu, J., and Bhalla, K. (2007) Clin. Cancer Res. 13, 4882-4890
27. Kovacs, J. J., Murphy, P. J., Gaillard, S., Zhao, X., Wu, J. T., Nicchitta, C. V., Yoshida, M., Toft, D. O., Pratt, W. B., and Yao, T. P. (2005) Mol. Cell 18, 601-607
28. Bali, P., Pranpat, M., Bradner, J., Balasis, M., Fiskus, W., Guo, F., Rocha, K., Kumaraswamy, S., Boyapalle, S., Atadja, P., Seto, E., and Bhalla, K. (2005) J. Biol. Chem. 280, 26729-26734
29. Murphy, P. J., Morishima, Y., Kovacs, J. J., Yao, T. P., and Pratt, W. B. (2005) J. Biol. Chem. 280, 33792-33799
30. Scroggins, B. T., Robzyk, K., Wang, D., Marcu, M. G., Tsutsumi, S., Beebe, K., Cotter, R. J., Felts, S., Toft, D., Karnitz, L., Rosen, N., and Neckers, L. (2007) Mol. Cell 25, 151-159
31. Tanaka, H., Shibagaki, I., Shimada, Y., Wagata, T., Imamura, M., and Ishizaki, K. (1996) Int. J. Cancer 65, 372-376
32. Marsh, K. A., Stamp, G. W., and Kirkland, S. C. (1993) J. Pathol. 170, 441-450
33. Sacks, P., Parnes, S. M., Gallick, G. E., Mansouri, Z., Lichtner, R., Satya-Prakash, K. I., Pathak, S., and Parsons, D. F. (1988) Cancer Res. 48, 2858-2866
34. Mitsudomi, T., Viallet, J., Mulshine, J. L., Linnoila, R. I., Minna, J. D., and Gazdar, A. F. (1991) Oncogene 6, 1353-1362
35. Sacks, P. G. (1996) Cancer Metastasis Rev. 15, 27-51
36. Du, B., Altorki, N. K., Kopelovich, L., Subbaramaiah, K., and Dannenberg, A. J. (2005) Cancer Res. 65, 5982-5988
37. Gümüs, Z., Du, B., Kacker, A., Boyle, J. O., Bocker, J. M., Mukherjee, P., Subbaramaiah, K., Dannenberg, A. J., and Weinstein, H. (2008) Cancer Prev. Res. 1, 100-111
38. Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J. (1951) J. Biol. Chem. 193, 265-275
39. Laemmli, U. K. (1970) Nature 227, 680-685
40. Towbin, H., Staehelin, T., and Gordon, J. (1979) Proc. Natl. Acad. Sci. U. S. A. 76, 4350-4354
41. Matthews, J., Wihlen, B., Thomsen, J., and Gustafsson, J.-A. (2005) Mol. Cell. Biol. 25, 5317-5328
42. Kang, H. J., Kim, H. J., Kim, S. K., Barouki, R., Cho, C. H., Khanna, K. K., Rosen, E. M., and Bae, I. (2006) J. Biol. Chem. 28, 14654-14662
43. Haggarty, S. J., Koeller, K. M., Wong, J. C., Grozinger, C. M., and Schreiber, S. L. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 4389-4394
44. Whitelaw, M. L., McGuire, J., Picard, D., Gustafsson, J.-A., and Poellinger, L. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 4437-4441
45. Chen, H. S., Sing, S. S., and Perdew, G. H. (1997) Arch. Biochem. Biophys. 348, 190-198
46. Hughes, D., Guttenplan, J. B., Marcus, C. B., Subbaramaiah, K., and Dannenberg, A. J. (2008) Cancer Prev. Res. 1, 485-493
47. Lee, Y. S., Lim, K. H., Guo, X., Kawaguchi, Y., Gao, Y., Barrientos, T., Ordentlich, P., Wang, X. F., Counter, C. M., and Yao, T. P. (2008) Cancer Res. 68, 7561-7569
48. Ramadoss, P., Marcus, C., and Perdew, G. H. (2005) Expert Opin. Metab. Toxicol., 1, 9-21
49. Volk, D. E., Thiviyanathan, V., Rice, J. S., Luxon, B. A., Shah, J. H., Yagi, H., Sayer, J. M., Yeh, H. J. C., Jerina, D. M., and Gorenstein, D. G. (2003) Biochemistry 42, 1410-1420
50. Spira, A., Beane, J., Shah, V., Liu, G., Schembri, F., Yang, X., Palma, J., and Brody, J. S. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 10143-10148