Different soluble forms of the interleukin-6 family signal transducer gp130 fine-tune the blockade of interleukin-6 trans-signaling

Journal of Biological Chemistry

Volumn 291, Issue 31, 2016, Pages 16186-16196

  Wolf, Janina ^a   Waetzig, Georg H ^b   Chalaris, Athena ^a   Reinheimer, Torsten M ^c   Wege, Henning ^d   Rose John, Stefan ^a   Garbers, Christoph ^a  

^a UNIVERSITY OF KIEL   (Germany)

^b CONARIS Research Institute AG ^*  (Germany)

^c Ferring Pharmaceuticals AS   (Denmark)

^d UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROLIFERATION; CELLS; CYTOLOGY; DISEASES; IMMUNOLOGY; SIGNALING;

CELL TYPES; ECTODOMAIN SHEDDING; INFLAMMATORY DISEASE; INTERLEUKIN-6; MEMBRANE-BOUND; METALLOPROTEASES; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCERS;

CELL SIGNALING;

ADAM PROTEIN; ADAM10 ENDOPEPTIDASE; ADAM17 PROTEIN; GLYCOPROTEIN GP 130; INTERLEUKIN 6; MESSENGER RNA; SOLUBLE FORM OF GLYCOPROTEIN 130 E10; SOLUBLE FORM OF GLYCOPROTEIN 130 RHEUMATOID ARTHRITIS ASSOCIATED PEPTIDE; UNCLASSIFIED DRUG; ADAM10 PROTEIN, HUMAN; ADAM10 PROTEIN, MOUSE; ADAM17 PROTEIN, HUMAN; ADAM17 PROTEIN, MOUSE; IL6 PROTEIN, HUMAN; IL6ST PROTEIN, MOUSE; INTERLEUKIN-6, MOUSE; MEMBRANE PROTEIN; SECRETASE; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MACROPHAGE; MONOCYTE; MOUSE; NONHUMAN; PRE B LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; ANIMAL; GENETICS; HEK293 CELL LINE; HEP-G2 CELL LINE; METABOLISM; PHYSIOLOGY;

ADAM10 PROTEIN; ADAM17 PROTEIN; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; CYTOKINE RECEPTOR GP130; HEK293 CELLS; HEP G2 CELLS; HUMANS; INTERLEUKIN-6; MEMBRANE PROTEINS; MICE; PRECURSOR CELLS, B-LYMPHOID; SIGNAL TRANSDUCTION;

EID: 84979780142     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M116.718551     Document Type: Article

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