Shedding of the soluble IL-6 receptor is triggered by Ca2+ mobilization, while basal release is predominantly the product of differential mRNA splicing in THP-1 cells

European Journal of Immunology

Volumn 28, Issue 11, 1998, Pages 3514-3522

  Jones, Simon A ^a   Horiuchi, Sankichi ^b   Novick, Daniela ^c   Yamamoto, Naoki ^b   Fuller, Gerald M ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^c WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

IL 6; IL 6 receptor; Inflammation; Soluble receptor

Indexed keywords

BREFELDIN A; CALCIUM ION; CALCIUM IONOPHORE; INTERLEUKIN 6 RECEPTOR; IONOMYCIN; MESSENGER RNA; PROTEINASE INHIBITOR; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; INFLAMMATION; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA SPLICING;

ANIMALS; CALCIUM; CELL LINE; HUMANS; MICE; MICE, INBRED BALB C; PROTEIN KINASE C; RECEPTORS, INTERLEUKIN-6; RNA SPLICING; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0031795233     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4141(199811)28:11<3514::AID-IMMU3514>3.0.CO;2-T     Document Type: Article

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