A soluble form of the interleukin-6 family signal transducer gp130 is dimerized via a C-terminal disulfide bridge resulting from alternative mRNA splicing

Biochemical and Biophysical Research Communications

Volumn 470, Issue 4, 2016, Pages 870-876

  Wolf, Janina ^a   Waetzig, Georg H ^b   Reinheimer, Torsten M ^c   Scheller, Jürgen ^d   Rose John, Stefan ^a   Garbers, Christoph ^a  

^a UNIVERSITY OF KIEL   (Germany)

^b CONARIS Research Institute AG ^*  (Germany)

^c Ferring Pharmaceuticals AS   (Denmark)

^d Department of Orthopedic Surgery   (Germany)

Author keywords

Gp130; IL 6R; Interleukin 6; Sgp130; Trans signaling

Indexed keywords

DISULFIDE; GLYCOPROTEIN GP 130; MESSENGER RNA;

ALTERNATIVE RNA SPLICING; CHEMISTRY; GENETICS; HEK293 CELL LINE; HUMAN; PROTEIN TERTIARY STRUCTURE; SOLUBILITY; STRUCTURE ACTIVITY RELATION;

ALTERNATIVE SPLICING; CYTOKINE RECEPTOR GP130; DISULFIDES; HEK293 CELLS; HUMANS; PROTEIN STRUCTURE, TERTIARY; RNA, MESSENGER; SOLUBILITY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84957547865     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2016.01.127     Document Type: Article

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