A reductionist metastasis-on-a-chip platform for in vitro tumor progression modeling and drug screening

Biotechnology and Bioengineering

Volumn 113, Issue 9, 2016, Pages 2020-2032

  Skardal, Aleksander ^a,b   Devarasetty, Mahesh ^a,b   Forsythe, Steven ^a   Atala, Anthony ^a,b   Soker, Shay ^a,b  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b Virginia Tech Wake Forest School of Biomedical Engineering and Sciences   (United States)

Author keywords

cancer; diagnostics; hydrogel; in vitro models; organs on a chip

Indexed keywords

ANIMAL CELL CULTURE; BIOMECHANICS; CELL CULTURE; DISEASES; DRUG THERAPY; FLOW OF FLUIDS; HYALURONIC ACID; HYDROGELS; MOLECULAR BIOLOGY; PATHOLOGY; PLASMA DIAGNOSTICS; TISSUE; TUMORS;

CANCER; CELL CULTURE MODELS; CHEMOTHERAPEUTIC AGENTS; CIRCULATING FLUIDS; COLON CANCER CELLS; IN-VITRO MODELS; ORGANS-ON-A-CHIP; TUMOR PROGRESSIONS;

DIAGNOSIS;

BETA CATENIN; CYCLINE; FLUOROURACIL; GELATINASE B; HYALURONIC ACID; MARIMASTAT; NERVE CELL ADHESION MOLECULE; PROTEIN ZO1; TUMOR MARKER; VINCULIN;

ARTICLE; CELL MIGRATION; CELL PROLIFERATION; COLON CANCER; CONTROLLED STUDY; DRUG SCREENING; FLUID FLOW; HUMAN; HUMAN CELL; HYDROGEL; IN VITRO STUDY; MEDICAL DEVICE; MESENCHYME CELL; METASTASIS; METASTASIS ON A CHIP; PHENOTYPE; TUMOR GROWTH; TUMOR INVASION; TUMOR MODEL;

EID: 84979779795     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.25950     Document Type: Article

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