-
1
-
-
13844310310
-
Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer
-
Wang Y, Klijn JG, Zhang Y, Sieuwerts AM, Look MP, et al. (2005) Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer. Lancet 365: 671-679.
-
(2005)
Lancet
, vol.365
, pp. 671-679
-
-
Wang, Y.1
Klijn, J.G.2
Zhang, Y.3
Sieuwerts, A.M.4
Look, M.P.5
-
2
-
-
27144488136
-
Molecular portraits and 70-gene prognosis signature are preserved throughout the metastatic process of breast cancer
-
Weigelt B, Hu Z, He X, Livasy C, Carey LA, et al. (2005) Molecular portraits and 70-gene prognosis signature are preserved throughout the metastatic process of breast cancer. Cancer Res 65: 9155-9158.
-
(2005)
Cancer Res
, vol.65
, pp. 9155-9158
-
-
Weigelt, B.1
Hu, Z.2
He, X.3
Livasy, C.4
Carey, L.A.5
-
3
-
-
19944422061
-
A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer
-
Paik S, Shak S, Tang G, Kim C, Baker J, et al. (2004) A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer. N Engl J Med 351: 2817-2826.
-
(2004)
N Engl J Med
, vol.351
, pp. 2817-2826
-
-
Paik, S.1
Shak, S.2
Tang, G.3
Kim, C.4
Baker, J.5
-
4
-
-
19344364880
-
Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials
-
Early Breast Cancer Trialists' Collaborative Group
-
Early Breast Cancer Trialists' Collaborative Group (2005) Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials. Lancet 365: 1687-1717.
-
(2005)
Lancet
, vol.365
, pp. 1687-1717
-
-
-
5
-
-
37549055451
-
Adjuvant chemotherapy in oestrogen-receptor-poor breast cancer: patient-level meta-analysis of randomised trials
-
Clarke M, Coates AS, Darby SC, Davies C, Gelber RD, et al. (2008) Adjuvant chemotherapy in oestrogen-receptor-poor breast cancer: patient-level meta-analysis of randomised trials. Lancet 371: 29-40.
-
(2008)
Lancet
, vol.371
, pp. 29-40
-
-
Clarke, M.1
Coates, A.S.2
Darby, S.C.3
Davies, C.4
Gelber, R.D.5
-
6
-
-
84863105627
-
Circulating tumour cells in non-metastatic breast cancer: a prospective study
-
Lucci A, Hall CS, Lodhi AK, Bhattacharyya A, Anderson AE, et al. (2012) Circulating tumour cells in non-metastatic breast cancer: a prospective study. Lancet Oncol 13: 688-695.
-
(2012)
Lancet Oncol
, vol.13
, pp. 688-695
-
-
Lucci, A.1
Hall, C.S.2
Lodhi, A.K.3
Bhattacharyya, A.4
Anderson, A.E.5
-
7
-
-
33845914033
-
The clinical significance of disseminated tumor cells in breast cancer
-
Slade MJ, Coombes RC, (2007) The clinical significance of disseminated tumor cells in breast cancer. Nat Clin Pract Oncol 4: 30-41.
-
(2007)
Nat Clin Pract Oncol
, vol.4
, pp. 30-41
-
-
Slade, M.J.1
Coombes, R.C.2
-
8
-
-
35548936833
-
Models, mechanisms and clinical evidence for cancer dormancy
-
Aguirre-Ghiso JA, (2007) Models, mechanisms and clinical evidence for cancer dormancy. Nat Rev Cancer 7: 834-846.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 834-846
-
-
Aguirre-Ghiso, J.A.1
-
9
-
-
84855493107
-
Disseminated tumor cells predict survival after neoadjuvant therapy in primary breast cancer
-
Hall C, Krishnamurthy S, Lodhi A, Bhattacharyya A, Anderson A, et al. (2012) Disseminated tumor cells predict survival after neoadjuvant therapy in primary breast cancer. Cancer 118: 342-348.
-
(2012)
Cancer
, vol.118
, pp. 342-348
-
-
Hall, C.1
Krishnamurthy, S.2
Lodhi, A.3
Bhattacharyya, A.4
Anderson, A.5
-
10
-
-
78649467513
-
Does tumour dormancy offer a therapeutic target?
-
Goss PE, Chambers AF, (2010) Does tumour dormancy offer a therapeutic target? Nat Rev Cancer 10: 871-877.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 871-877
-
-
Goss, P.E.1
Chambers, A.F.2
-
11
-
-
37349079197
-
Systemic spread is an early step in breast cancer
-
Husemann Y, Geigl JB, Schubert F, Musiani P, Meyer M, et al. (2008) Systemic spread is an early step in breast cancer. Cancer Cell 13: 58-68.
-
(2008)
Cancer Cell
, vol.13
, pp. 58-68
-
-
Husemann, Y.1
Geigl, J.B.2
Schubert, F.3
Musiani, P.4
Meyer, M.5
-
12
-
-
24944534497
-
Genomic analysis of single cytokeratin-positive cells from bone marrow reveals early mutational events in breast cancer
-
Schardt JA, Meyer M, Hartmann CH, Schubert F, Schmidt-Kittler O, et al. (2005) Genomic analysis of single cytokeratin-positive cells from bone marrow reveals early mutational events in breast cancer. Cancer Cell 8: 227-239.
-
(2005)
Cancer Cell
, vol.8
, pp. 227-239
-
-
Schardt, J.A.1
Meyer, M.2
Hartmann, C.H.3
Schubert, F.4
Schmidt-Kittler, O.5
-
13
-
-
0037206022
-
Genetic heterogeneity of single disseminated tumour cells in minimal residual cancer
-
Klein CA, Blankenstein TJ, Schmidt-Kittler O, Petronio M, Polzer B, et al. (2002) Genetic heterogeneity of single disseminated tumour cells in minimal residual cancer. Lancet 360: 683-689.
-
(2002)
Lancet
, vol.360
, pp. 683-689
-
-
Klein, C.A.1
Blankenstein, T.J.2
Schmidt-Kittler, O.3
Petronio, M.4
Polzer, B.5
-
14
-
-
41649098379
-
Breast cancer metastases are molecularly distinct from their primary tumors
-
Vecchi M, Confalonieri S, Nuciforo P, Vigano MA, Capra M, et al. (2008) Breast cancer metastases are molecularly distinct from their primary tumors. Oncogene 27: 2148-2158.
-
(2008)
Oncogene
, vol.27
, pp. 2148-2158
-
-
Vecchi, M.1
Confalonieri, S.2
Nuciforo, P.3
Vigano, M.A.4
Capra, M.5
-
15
-
-
0346734120
-
Gene expression profiles of primary breast tumors maintained in distant metastases
-
Weigelt B, Glas AM, Wessels LF, Witteveen AT, Peterse JL, et al. (2003) Gene expression profiles of primary breast tumors maintained in distant metastases. Proc Natl Acad Sci U S A 100: 15901-15905.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 15901-15905
-
-
Weigelt, B.1
Glas, A.M.2
Wessels, L.F.3
Witteveen, A.T.4
Peterse, J.L.5
-
16
-
-
77951139631
-
Genome remodelling in a basal-like breast cancer metastasis and xenograft
-
Ding L, Ellis MJ, Li S, Larson DE, Chen K, et al. (2010) Genome remodelling in a basal-like breast cancer metastasis and xenograft. Nature 464: 999-1005.
-
(2010)
Nature
, vol.464
, pp. 999-1005
-
-
Ding, L.1
Ellis, M.J.2
Li, S.3
Larson, D.E.4
Chen, K.5
-
17
-
-
0037226593
-
A molecular signature of metastasis in primary solid tumors
-
Ramaswamy S, Ross KN, Lander ES, Golub TR, (2003) A molecular signature of metastasis in primary solid tumors. Nat Genet 33: 49-54.
-
(2003)
Nat Genet
, vol.33
, pp. 49-54
-
-
Ramaswamy, S.1
Ross, K.N.2
Lander, E.S.3
Golub, T.R.4
-
19
-
-
77950809059
-
A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations
-
Sharma SV, Lee DY, Li B, Quinlan MP, Takahashi F, et al. (2010) A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations. Cell 141: 69-80.
-
(2010)
Cell
, vol.141
, pp. 69-80
-
-
Sharma, S.V.1
Lee, D.Y.2
Li, B.3
Quinlan, M.P.4
Takahashi, F.5
-
20
-
-
0034860222
-
Solitary cancer cells as a possible source of tumour dormancy?
-
Naumov GN, MacDonald IC, Chambers AF, Groom AC, (2001) Solitary cancer cells as a possible source of tumour dormancy? Semin Cancer Biol 11: 271-276.
-
(2001)
Semin Cancer Biol
, vol.11
, pp. 271-276
-
-
Naumov, G.N.1
MacDonald, I.C.2
Chambers, A.F.3
Groom, A.C.4
-
21
-
-
67649300721
-
Genes that mediate breast cancer metastasis to the brain
-
Bos PD, Zhang XH, Nadal C, Shu W, Gomis RR, et al. (2009) Genes that mediate breast cancer metastasis to the brain. Nature 459: 1005-1009.
-
(2009)
Nature
, vol.459
, pp. 1005-1009
-
-
Bos, P.D.1
Zhang, X.H.2
Nadal, C.3
Shu, W.4
Gomis, R.R.5
-
22
-
-
23144461051
-
Genes that mediate breast cancer metastasis to lung
-
Minn AJ, Gupta GP, Siegel PM, Bos PD, Shu W, et al. (2005) Genes that mediate breast cancer metastasis to lung. Nature 436: 518-524.
-
(2005)
Nature
, vol.436
, pp. 518-524
-
-
Minn, A.J.1
Gupta, G.P.2
Siegel, P.M.3
Bos, P.D.4
Shu, W.5
-
23
-
-
0017704436
-
Metastasis results from preexisting variant cells within a malignant tumor
-
Fidler IJ, Kripke ML, (1977) Metastasis results from preexisting variant cells within a malignant tumor. Science 197: 893-895.
-
(1977)
Science
, vol.197
, pp. 893-895
-
-
Fidler, I.J.1
Kripke, M.L.2
-
24
-
-
17844406154
-
Expression profiling of primary tumors and matched lymphatic and lung metastases in a xenogeneic breast cancer model
-
Montel V, Huang TY, Mose E, Pestonjamasp K, Tarin D, (2005) Expression profiling of primary tumors and matched lymphatic and lung metastases in a xenogeneic breast cancer model. Am J Pathol 166: 1565-1579.
-
(2005)
Am J Pathol
, vol.166
, pp. 1565-1579
-
-
Montel, V.1
Huang, T.Y.2
Mose, E.3
Pestonjamasp, K.4
Tarin, D.5
-
25
-
-
0038488950
-
A multigenic program mediating breast cancer metastasis to bone
-
Kang Y, Siegel PM, Shu W, Drobnjak M, Kakonen SM, et al. (2003) A multigenic program mediating breast cancer metastasis to bone. Cancer Cell 3: 537-549.
-
(2003)
Cancer Cell
, vol.3
, pp. 537-549
-
-
Kang, Y.1
Siegel, P.M.2
Shu, W.3
Drobnjak, M.4
Kakonen, S.M.5
-
26
-
-
84864285223
-
RNA sequencing of pancreatic circulating tumour cells implicates WNT signalling in metastasis
-
Yu M, Ting DT, Stott SL, Wittner BS, Ozsolak F, et al. (2012) RNA sequencing of pancreatic circulating tumour cells implicates WNT signalling in metastasis. Nature 487: 510-513.
-
(2012)
Nature
, vol.487
, pp. 510-513
-
-
Yu, M.1
Ting, D.T.2
Stott, S.L.3
Wittner, B.S.4
Ozsolak, F.5
-
27
-
-
0142244181
-
Progression to malignancy in the polyoma middle T oncoprotein mouse breast cancer model provides a reliable model for human diseases
-
Lin EY, Jones JG, Li P, Zhu L, Whitney KD, et al. (2003) Progression to malignancy in the polyoma middle T oncoprotein mouse breast cancer model provides a reliable model for human diseases. Am J Pathol 163: 2113-2126.
-
(2003)
Am J Pathol
, vol.163
, pp. 2113-2126
-
-
Lin, E.Y.1
Jones, J.G.2
Li, P.3
Zhu, L.4
Whitney, K.D.5
-
28
-
-
0026587657
-
Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease
-
Guy CT, Cardiff RD, Muller WJ, (1992) Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease. Mol Cell Biol 12: 954-961.
-
(1992)
Mol Cell Biol
, vol.12
, pp. 954-961
-
-
Guy, C.T.1
Cardiff, R.D.2
Muller, W.J.3
-
29
-
-
33845867158
-
Polyoma and SV40 proteins differentially regulate PP2A to activate distinct cellular signaling pathways involved in growth control
-
Rodriguez-Viciana P, Collins C, Fried M, (2006) Polyoma and SV40 proteins differentially regulate PP2A to activate distinct cellular signaling pathways involved in growth control. Proc Natl Acad Sci U S A 103: 19290-19295.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 19290-19295
-
-
Rodriguez-Viciana, P.1
Collins, C.2
Fried, M.3
-
30
-
-
34548863946
-
Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors
-
Herschkowitz JI, Simin K, Weigman VJ, Mikaelian I, Usary J, et al. (2007) Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors. Genome Biol 8: R76.
-
(2007)
Genome Biol
, vol.8
-
-
Herschkowitz, J.I.1
Simin, K.2
Weigman, V.J.3
Mikaelian, I.4
Usary, J.5
-
31
-
-
38549131901
-
GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model
-
Kouros-Mehr H, Bechis SK, Slorach EM, Littlepage LE, Egeblad M, et al. (2008) GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model. Cancer Cell 13: 141-152.
-
(2008)
Cancer Cell
, vol.13
, pp. 141-152
-
-
Kouros-Mehr, H.1
Bechis, S.K.2
Slorach, E.M.3
Littlepage, L.E.4
Egeblad, M.5
-
32
-
-
35748949257
-
A comparison of background correction methods for two-colour microarrays
-
Ritchie ME, Silver J, Oshlack A, Holmes M, Diyagama D, et al. (2007) A comparison of background correction methods for two-colour microarrays. Bioinformatics 23: 2700-2707.
-
(2007)
Bioinformatics
, vol.23
, pp. 2700-2707
-
-
Ritchie, M.E.1
Silver, J.2
Oshlack, A.3
Holmes, M.4
Diyagama, D.5
-
33
-
-
33745696736
-
Toxicity and health-related quality of life in breast cancer patients receiving adjuvant docetaxel, doxorubicin, cyclophosphamide (TAC) or 5-fluorouracil, doxorubicin and cyclophosphamide (FAC): impact of adding primary prophylactic granulocyte-colony stimulating factor to the TAC regimen
-
Martin M, Lluch A, Segui MA, Ruiz A, Ramos M, et al. (2006) Toxicity and health-related quality of life in breast cancer patients receiving adjuvant docetaxel, doxorubicin, cyclophosphamide (TAC) or 5-fluorouracil, doxorubicin and cyclophosphamide (FAC): impact of adding primary prophylactic granulocyte-colony stimulating factor to the TAC regimen. Ann Oncol 17: 1205-1212.
-
(2006)
Ann Oncol
, vol.17
, pp. 1205-1212
-
-
Martin, M.1
Lluch, A.2
Segui, M.A.3
Ruiz, A.4
Ramos, M.5
-
34
-
-
34547742663
-
Signal transducer and activator of transcription 1 in breast cancer: analysis with tissue microarray
-
Sheen-Chen SM, Huang CC, Tang RP, Yang CH, Chou FF, et al. (2007) Signal transducer and activator of transcription 1 in breast cancer: analysis with tissue microarray. Anticancer Res 27: 2481-2486.
-
(2007)
Anticancer Res
, vol.27
, pp. 2481-2486
-
-
Sheen-Chen, S.M.1
Huang, C.C.2
Tang, R.P.3
Yang, C.H.4
Chou, F.F.5
-
35
-
-
1242319531
-
STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells
-
Khodarev NN, Beckett M, Labay E, Darga T, Roizman B, et al. (2004) STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells. Proc Natl Acad Sci U S A 101: 1714-1719.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 1714-1719
-
-
Khodarev, N.N.1
Beckett, M.2
Labay, E.3
Darga, T.4
Roizman, B.5
-
36
-
-
67149111590
-
STAT1 pathway mediates amplification of metastatic potential and resistance to therapy
-
Khodarev NN, Roach P, Pitroda SP, Golden DW, Bhayani M, et al. (2009) STAT1 pathway mediates amplification of metastatic potential and resistance to therapy. PLoS One 4: e5821.
-
(2009)
PLoS One
, vol.4
-
-
Khodarev, N.N.1
Roach, P.2
Pitroda, S.P.3
Golden, D.W.4
Bhayani, M.5
-
37
-
-
21044456453
-
STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage
-
Townsend PA, Cragg MS, Davidson SM, McCormick J, Barry S, et al. (2005) STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage. J Cell Sci 118: 1629-1639.
-
(2005)
J Cell Sci
, vol.118
, pp. 1629-1639
-
-
Townsend, P.A.1
Cragg, M.S.2
Davidson, S.M.3
McCormick, J.4
Barry, S.5
-
38
-
-
0028923658
-
Elevated levels of members of the STAT family of transcription factors in breast carcinoma nuclear extracts
-
Watson CJ, Miller WR, (1995) Elevated levels of members of the STAT family of transcription factors in breast carcinoma nuclear extracts. Br J Cancer 71: 840-844.
-
(1995)
Br J Cancer
, vol.71
, pp. 840-844
-
-
Watson, C.J.1
Miller, W.R.2
-
39
-
-
7244245445
-
Roles and regulation of stat family transcription factors in human breast cancer
-
Clevenger CV, (2004) Roles and regulation of stat family transcription factors in human breast cancer. Am J Pathol 165: 1449-1460.
-
(2004)
Am J Pathol
, vol.165
, pp. 1449-1460
-
-
Clevenger, C.V.1
-
40
-
-
0034680102
-
Molecular portraits of human breast tumours
-
Perou CM, Sorlie T, Eisen MB, van de Rijn M, Jeffrey SS, et al. (2000) Molecular portraits of human breast tumours. Nature 406: 747-752.
-
(2000)
Nature
, vol.406
, pp. 747-752
-
-
Perou, C.M.1
Sorlie, T.2
Eisen, M.B.3
van de Rijn, M.4
Jeffrey, S.S.5
-
41
-
-
9644310201
-
Molecular portraits of breast cancer: tumour subtypes as distinct disease entities
-
Sorlie T, (2004) Molecular portraits of breast cancer: tumour subtypes as distinct disease entities. Eur J Cancer 40: 2667-2675.
-
(2004)
Eur J Cancer
, vol.40
, pp. 2667-2675
-
-
Sorlie, T.1
-
42
-
-
33745834662
-
Distinct molecular mechanisms underlying clinically relevant subtypes of breast cancer: gene expression analyses across three different platforms
-
Sorlie T, Wang Y, Xiao C, Johnsen H, Naume B, et al. (2006) Distinct molecular mechanisms underlying clinically relevant subtypes of breast cancer: gene expression analyses across three different platforms. BMC Genomics 7: 127.
-
(2006)
BMC Genomics
, vol.7
, pp. 127
-
-
Sorlie, T.1
Wang, Y.2
Xiao, C.3
Johnsen, H.4
Naume, B.5
-
43
-
-
34250652449
-
Strong time dependence of the 76-gene prognostic signature for node-negative breast cancer patients in the TRANSBIG multicenter independent validation series
-
Desmedt C, Piette F, Loi S, Wang Y, Lallemand F, et al. (2007) Strong time dependence of the 76-gene prognostic signature for node-negative breast cancer patients in the TRANSBIG multicenter independent validation series. Clin Cancer Res 13: 3207-3214.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 3207-3214
-
-
Desmedt, C.1
Piette, F.2
Loi, S.3
Wang, Y.4
Lallemand, F.5
-
44
-
-
33845209913
-
A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes
-
Neve RM, Chin K, Fridlyand J, Yeh J, Baehner FL, et al. (2006) A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell 10: 515-527.
-
(2006)
Cancer Cell
, vol.10
, pp. 515-527
-
-
Neve, R.M.1
Chin, K.2
Fridlyand, J.3
Yeh, J.4
Baehner, F.L.5
-
45
-
-
33845191779
-
Genomic and transcriptional aberrations linked to breast cancer pathophysiologies
-
Chin K, DeVries S, Fridlyand J, Spellman PT, Roydasgupta R, et al. (2006) Genomic and transcriptional aberrations linked to breast cancer pathophysiologies. Cancer Cell 10: 529-541.
-
(2006)
Cancer Cell
, vol.10
, pp. 529-541
-
-
Chin, K.1
DeVries, S.2
Fridlyand, J.3
Spellman, P.T.4
Roydasgupta, R.5
-
46
-
-
0042838307
-
Breast cancer classification and prognosis based on gene expression profiles from a population-based study
-
Sotiriou C, Neo SY, McShane LM, Korn EL, Long PM, et al. (2003) Breast cancer classification and prognosis based on gene expression profiles from a population-based study. Proc Natl Acad Sci U S A 100: 10393-10398.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 10393-10398
-
-
Sotiriou, C.1
Neo, S.Y.2
McShane, L.M.3
Korn, E.L.4
Long, P.M.5
-
47
-
-
79959956046
-
The JAK2/STAT3 signaling pathway is required for growth of CD44(+)CD24(-) stem cell-like breast cancer cells in human tumors
-
Marotta LL, Almendro V, Marusyk A, Shipitsin M, Schemme J, et al. (2011) The JAK2/STAT3 signaling pathway is required for growth of CD44(+)CD24(-) stem cell-like breast cancer cells in human tumors. J Clin Invest 121: 2723-2735.
-
(2011)
J Clin Invest
, vol.121
, pp. 2723-2735
-
-
Marotta, L.L.1
Almendro, V.2
Marusyk, A.3
Shipitsin, M.4
Schemme, J.5
-
48
-
-
34248545443
-
Gene expression profiling of breast, prostate, and glioma cells following single versus fractionated doses of radiation
-
Tsai MH, Cook JA, Chandramouli GV, DeGraff W, Yan H, et al. (2007) Gene expression profiling of breast, prostate, and glioma cells following single versus fractionated doses of radiation. Cancer Res 67: 3845-3852.
-
(2007)
Cancer Res
, vol.67
, pp. 3845-3852
-
-
Tsai, M.H.1
Cook, J.A.2
Chandramouli, G.V.3
DeGraff, W.4
Yan, H.5
-
49
-
-
33644683611
-
GBP1 overexpression is associated with a paclitaxel resistance phenotype
-
Duan Z, Foster R, Brakora KA, Yusuf RZ, Seiden MV, (2006) GBP1 overexpression is associated with a paclitaxel resistance phenotype. Cancer Chemother Pharmacol 57: 25-33.
-
(2006)
Cancer Chemother Pharmacol
, vol.57
, pp. 25-33
-
-
Duan, Z.1
Foster, R.2
Brakora, K.A.3
Yusuf, R.Z.4
Seiden, M.V.5
-
50
-
-
57449088412
-
An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer
-
Weichselbaum RR, Ishwaran H, Yoon T, Nuyten DS, Baker SW, et al. (2008) An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer. Proc Natl Acad Sci U S A 105: 18490-18495.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 18490-18495
-
-
Weichselbaum, R.R.1
Ishwaran, H.2
Yoon, T.3
Nuyten, D.S.4
Baker, S.W.5
-
51
-
-
33845384469
-
STAT1 signaling is associated with acquired crossresistance to doxorubicin and radiation in myeloma cell lines
-
Fryknas M, Dhar S, Oberg F, Rickardson L, Rydaker M, et al. (2007) STAT1 signaling is associated with acquired crossresistance to doxorubicin and radiation in myeloma cell lines. Int J Cancer 120: 189-195.
-
(2007)
Int J Cancer
, vol.120
, pp. 189-195
-
-
Fryknas, M.1
Dhar, S.2
Oberg, F.3
Rickardson, L.4
Rydaker, M.5
-
52
-
-
24944521677
-
Identification of molecular mechanisms for cellular drug resistance by combining drug activity and gene expression profiles
-
Rickardson L, Fryknas M, Dhar S, Lovborg H, Gullbo J, et al. (2005) Identification of molecular mechanisms for cellular drug resistance by combining drug activity and gene expression profiles. Br J Cancer 93: 483-492.
-
(2005)
Br J Cancer
, vol.93
, pp. 483-492
-
-
Rickardson, L.1
Fryknas, M.2
Dhar, S.3
Lovborg, H.4
Gullbo, J.5
-
53
-
-
33749825228
-
Novel role of Stat1 in the development of docetaxel resistance in prostate tumor cells
-
Patterson SG, Wei S, Chen X, Sallman DA, Gilvary DL, et al. (2006) Novel role of Stat1 in the development of docetaxel resistance in prostate tumor cells. Oncogene 25: 6113-6122.
-
(2006)
Oncogene
, vol.25
, pp. 6113-6122
-
-
Patterson, S.G.1
Wei, S.2
Chen, X.3
Sallman, D.A.4
Gilvary, D.L.5
-
54
-
-
17444362227
-
Identification of genes associated with platinum drug sensitivity and resistance in human ovarian cancer cells
-
Roberts D, Schick J, Conway S, Biade S, Laub PB, et al. (2005) Identification of genes associated with platinum drug sensitivity and resistance in human ovarian cancer cells. Br J Cancer 92: 1149-1158.
-
(2005)
Br J Cancer
, vol.92
, pp. 1149-1158
-
-
Roberts, D.1
Schick, J.2
Conway, S.3
Biade, S.4
Laub, P.B.5
-
55
-
-
79956300159
-
A novel requirement for Janus kinases as mediators of drug resistance induced by fibroblast growth factor-2 in human cancer cells
-
Carmo CR, Lyons-Lewis J, Seckl MJ, Costa-Pereira AP, (2011) A novel requirement for Janus kinases as mediators of drug resistance induced by fibroblast growth factor-2 in human cancer cells. PLoS One 6: e19861.
-
(2011)
PLoS One
, vol.6
-
-
Carmo, C.R.1
Lyons-Lewis, J.2
Seckl, M.J.3
Costa-Pereira, A.P.4
-
56
-
-
77958501473
-
DNA damage-mediated induction of a chemoresistant niche
-
Gilbert LA, Hemann MT, (2010) DNA damage-mediated induction of a chemoresistant niche. Cell 143: 355-366.
-
(2010)
Cell
, vol.143
, pp. 355-366
-
-
Gilbert, L.A.1
Hemann, M.T.2
-
57
-
-
79958161210
-
Deactivation of signal transducer and activator of transcription 3 reverses chemotherapeutics resistance of leukemia cells via down-regulating P-gp
-
Zhang X, Xiao W, Wang L, Tian Z, Zhang J, (2011) Deactivation of signal transducer and activator of transcription 3 reverses chemotherapeutics resistance of leukemia cells via down-regulating P-gp. PLoS One 6: e20965.
-
(2011)
PLoS One
, vol.6
-
-
Zhang, X.1
Xiao, W.2
Wang, L.3
Tian, Z.4
Zhang, J.5
-
58
-
-
0037206950
-
Resistance to chemotherapy via Stat3-dependent overexpression of Bcl-2 in metastatic breast cancer cells
-
Real PJ, Sierra A, De Juan A, Segovia JC, Lopez-Vega JM, et al. (2002) Resistance to chemotherapy via Stat3-dependent overexpression of Bcl-2 in metastatic breast cancer cells. Oncogene 21: 7611-7618.
-
(2002)
Oncogene
, vol.21
, pp. 7611-7618
-
-
Real, P.J.1
Sierra, A.2
De Juan, A.3
Segovia, J.C.4
Lopez-Vega, J.M.5
-
59
-
-
0033036097
-
Serum interleukin-6 levels correlate to tumor progression and prognosis in metastatic breast carcinoma
-
Zhang GJ, Adachi I, (1999) Serum interleukin-6 levels correlate to tumor progression and prognosis in metastatic breast carcinoma. Anticancer Res 19: 1427-1432.
-
(1999)
Anticancer Res
, vol.19
, pp. 1427-1432
-
-
Zhang, G.J.1
Adachi, I.2
-
60
-
-
0037455841
-
Circulating interleukin-6 predicts survival in patients with metastatic breast cancer
-
Salgado R, Junius S, Benoy I, Van Dam P, Vermeulen P, et al. (2003) Circulating interleukin-6 predicts survival in patients with metastatic breast cancer. Int J Cancer 103: 642-646.
-
(2003)
Int J Cancer
, vol.103
, pp. 642-646
-
-
Salgado, R.1
Junius, S.2
Benoy, I.3
Van Dam, P.4
Vermeulen, P.5
-
61
-
-
34447506658
-
Oncogenic Ras-induced secretion of IL6 is required for tumorigenesis
-
Ancrile B, Lim KH, Counter CM, (2007) Oncogenic Ras-induced secretion of IL6 is required for tumorigenesis. Genes Dev 21: 1714-1719.
-
(2007)
Genes Dev
, vol.21
, pp. 1714-1719
-
-
Ancrile, B.1
Lim, K.H.2
Counter, C.M.3
-
62
-
-
0035799531
-
Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells
-
Garcia R, Bowman TL, Niu G, Yu H, Minton S, et al. (2001) Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells. Oncogene 20: 2499-2513.
-
(2001)
Oncogene
, vol.20
, pp. 2499-2513
-
-
Garcia, R.1
Bowman, T.L.2
Niu, G.3
Yu, H.4
Minton, S.5
-
63
-
-
33947414063
-
Significance of interleukin-6 (IL-6) in breast cancer (review)
-
Knupfer H, Preiss R, (2007) Significance of interleukin-6 (IL-6) in breast cancer (review). Breast Cancer Res Treat 102: 129-135.
-
(2007)
Breast Cancer Res Treat
, vol.102
, pp. 129-135
-
-
Knupfer, H.1
Preiss, R.2
-
64
-
-
80052855899
-
Interleukin-6 as a therapeutic target in human ovarian cancer
-
Coward J, Kulbe H, Chakravarty P, Leader D, Vassileva V, et al. (2011) Interleukin-6 as a therapeutic target in human ovarian cancer. Clin Cancer Res 17: 6083-6096.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 6083-6096
-
-
Coward, J.1
Kulbe, H.2
Chakravarty, P.3
Leader, D.4
Vassileva, V.5
-
65
-
-
70949094349
-
The JAK2 inhibitor AZD1480 potently blocks Stat3 signaling and oncogenesis in solid tumors
-
Hedvat M, Huszar D, Herrmann A, Gozgit JM, Schroeder A, et al. (2009) The JAK2 inhibitor AZD1480 potently blocks Stat3 signaling and oncogenesis in solid tumors. Cancer Cell 16: 487-497.
-
(2009)
Cancer Cell
, vol.16
, pp. 487-497
-
-
Hedvat, M.1
Huszar, D.2
Herrmann, A.3
Gozgit, J.M.4
Schroeder, A.5
-
66
-
-
84867919330
-
Targeting Notch, a key pathway for ovarian cancer stem cells, sensitizes tumors to platinum therapy
-
McAuliffe SM, Morgan SL, Wyant GA, Tran LT, Muto KW, et al. (2012) Targeting Notch, a key pathway for ovarian cancer stem cells, sensitizes tumors to platinum therapy. Proc Natl Acad Sci U S A 109: E2939-2948.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
-
-
McAuliffe, S.M.1
Morgan, S.L.2
Wyant, G.A.3
Tran, L.T.4
Muto, K.W.5
-
67
-
-
77953700950
-
Targeting Notch to target cancer stem cells
-
Pannuti A, Foreman K, Rizzo P, Osipo C, Golde T, et al. (2010) Targeting Notch to target cancer stem cells. Clin Cancer Res 16: 3141-3152.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 3141-3152
-
-
Pannuti, A.1
Foreman, K.2
Rizzo, P.3
Osipo, C.4
Golde, T.5
-
68
-
-
84859893371
-
Histone methylation: a dynamic mark in health, disease and inheritance
-
Greer EL, Shi Y, (2012) Histone methylation: a dynamic mark in health, disease and inheritance. Nat Rev Genet 13: 343-357.
-
(2012)
Nat Rev Genet
, vol.13
, pp. 343-357
-
-
Greer, E.L.1
Shi, Y.2
-
69
-
-
77049099785
-
Histone methyltransferases in cancer
-
Albert M, Helin K, (2010) Histone methyltransferases in cancer. Semin Cell Dev Biol 21: 209-220.
-
(2010)
Semin Cell Dev Biol
, vol.21
, pp. 209-220
-
-
Albert, M.1
Helin, K.2
-
70
-
-
84864434739
-
Emerging epigenetic targets and therapies in cancer medicine
-
Popovic R, Licht JD, (2012) Emerging epigenetic targets and therapies in cancer medicine. Cancer Discov 2: 405-413.
-
(2012)
Cancer Discov
, vol.2
, pp. 405-413
-
-
Popovic, R.1
Licht, J.D.2
-
71
-
-
65149084552
-
Crosstalk between histone modifications during the DNA damage response
-
van Attikum H, Gasser SM, (2009) Crosstalk between histone modifications during the DNA damage response. Trends Cell Biol 19: 207-217.
-
(2009)
Trends Cell Biol
, vol.19
, pp. 207-217
-
-
van Attikum, H.1
Gasser, S.M.2
-
72
-
-
84879421605
-
The histone methyltransferase MMSET/WHSC1 activates TWIST1 to promote an epithelial-mesenchymal transition and invasive properties of prostate cancer
-
Ezponda T, Popovic R, Shah MY, Martinez-Garcia E, Zheng Y, et al. (2012) The histone methyltransferase MMSET/WHSC1 activates TWIST1 to promote an epithelial-mesenchymal transition and invasive properties of prostate cancer. Oncogene.
-
(2012)
Oncogene
-
-
Ezponda, T.1
Popovic, R.2
Shah, M.Y.3
Martinez-Garcia, E.4
Zheng, Y.5
-
73
-
-
78049307486
-
H3K9 histone methyltransferase G9a promotes lung cancer invasion and metastasis by silencing the cell adhesion molecule Ep-CAM
-
Chen MW, Hua KT, Kao HJ, Chi CC, Wei LH, et al. (2010) H3K9 histone methyltransferase G9a promotes lung cancer invasion and metastasis by silencing the cell adhesion molecule Ep-CAM. Cancer Res 70: 7830-7840.
-
(2010)
Cancer Res
, vol.70
, pp. 7830-7840
-
-
Chen, M.W.1
Hua, K.T.2
Kao, H.J.3
Chi, C.C.4
Wei, L.H.5
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