메뉴 건너뛰기




Volumn 8, Issue 3, 2013, Pages

Biomarkers of Residual Disease, Disseminated Tumor Cells, and Metastases in the MMTV-PyMT Breast Cancer Model

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CYCLOPHOSPHAMIDE; DOCETAXEL; DOXORUBICIN; JANUS KINASE; NOTCH RECEPTOR; STAT1 PROTEIN;

EID: 84874782595     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0058183     Document Type: Article
Times cited : (35)

References (73)
  • 1
    • 13844310310 scopus 로고    scopus 로고
    • Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer
    • Wang Y, Klijn JG, Zhang Y, Sieuwerts AM, Look MP, et al. (2005) Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer. Lancet 365: 671-679.
    • (2005) Lancet , vol.365 , pp. 671-679
    • Wang, Y.1    Klijn, J.G.2    Zhang, Y.3    Sieuwerts, A.M.4    Look, M.P.5
  • 2
    • 27144488136 scopus 로고    scopus 로고
    • Molecular portraits and 70-gene prognosis signature are preserved throughout the metastatic process of breast cancer
    • Weigelt B, Hu Z, He X, Livasy C, Carey LA, et al. (2005) Molecular portraits and 70-gene prognosis signature are preserved throughout the metastatic process of breast cancer. Cancer Res 65: 9155-9158.
    • (2005) Cancer Res , vol.65 , pp. 9155-9158
    • Weigelt, B.1    Hu, Z.2    He, X.3    Livasy, C.4    Carey, L.A.5
  • 3
    • 19944422061 scopus 로고    scopus 로고
    • A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer
    • Paik S, Shak S, Tang G, Kim C, Baker J, et al. (2004) A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer. N Engl J Med 351: 2817-2826.
    • (2004) N Engl J Med , vol.351 , pp. 2817-2826
    • Paik, S.1    Shak, S.2    Tang, G.3    Kim, C.4    Baker, J.5
  • 4
    • 19344364880 scopus 로고    scopus 로고
    • Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials
    • Early Breast Cancer Trialists' Collaborative Group
    • Early Breast Cancer Trialists' Collaborative Group (2005) Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials. Lancet 365: 1687-1717.
    • (2005) Lancet , vol.365 , pp. 1687-1717
  • 5
    • 37549055451 scopus 로고    scopus 로고
    • Adjuvant chemotherapy in oestrogen-receptor-poor breast cancer: patient-level meta-analysis of randomised trials
    • Clarke M, Coates AS, Darby SC, Davies C, Gelber RD, et al. (2008) Adjuvant chemotherapy in oestrogen-receptor-poor breast cancer: patient-level meta-analysis of randomised trials. Lancet 371: 29-40.
    • (2008) Lancet , vol.371 , pp. 29-40
    • Clarke, M.1    Coates, A.S.2    Darby, S.C.3    Davies, C.4    Gelber, R.D.5
  • 6
    • 84863105627 scopus 로고    scopus 로고
    • Circulating tumour cells in non-metastatic breast cancer: a prospective study
    • Lucci A, Hall CS, Lodhi AK, Bhattacharyya A, Anderson AE, et al. (2012) Circulating tumour cells in non-metastatic breast cancer: a prospective study. Lancet Oncol 13: 688-695.
    • (2012) Lancet Oncol , vol.13 , pp. 688-695
    • Lucci, A.1    Hall, C.S.2    Lodhi, A.K.3    Bhattacharyya, A.4    Anderson, A.E.5
  • 7
    • 33845914033 scopus 로고    scopus 로고
    • The clinical significance of disseminated tumor cells in breast cancer
    • Slade MJ, Coombes RC, (2007) The clinical significance of disseminated tumor cells in breast cancer. Nat Clin Pract Oncol 4: 30-41.
    • (2007) Nat Clin Pract Oncol , vol.4 , pp. 30-41
    • Slade, M.J.1    Coombes, R.C.2
  • 8
    • 35548936833 scopus 로고    scopus 로고
    • Models, mechanisms and clinical evidence for cancer dormancy
    • Aguirre-Ghiso JA, (2007) Models, mechanisms and clinical evidence for cancer dormancy. Nat Rev Cancer 7: 834-846.
    • (2007) Nat Rev Cancer , vol.7 , pp. 834-846
    • Aguirre-Ghiso, J.A.1
  • 9
    • 84855493107 scopus 로고    scopus 로고
    • Disseminated tumor cells predict survival after neoadjuvant therapy in primary breast cancer
    • Hall C, Krishnamurthy S, Lodhi A, Bhattacharyya A, Anderson A, et al. (2012) Disseminated tumor cells predict survival after neoadjuvant therapy in primary breast cancer. Cancer 118: 342-348.
    • (2012) Cancer , vol.118 , pp. 342-348
    • Hall, C.1    Krishnamurthy, S.2    Lodhi, A.3    Bhattacharyya, A.4    Anderson, A.5
  • 10
    • 78649467513 scopus 로고    scopus 로고
    • Does tumour dormancy offer a therapeutic target?
    • Goss PE, Chambers AF, (2010) Does tumour dormancy offer a therapeutic target? Nat Rev Cancer 10: 871-877.
    • (2010) Nat Rev Cancer , vol.10 , pp. 871-877
    • Goss, P.E.1    Chambers, A.F.2
  • 12
    • 24944534497 scopus 로고    scopus 로고
    • Genomic analysis of single cytokeratin-positive cells from bone marrow reveals early mutational events in breast cancer
    • Schardt JA, Meyer M, Hartmann CH, Schubert F, Schmidt-Kittler O, et al. (2005) Genomic analysis of single cytokeratin-positive cells from bone marrow reveals early mutational events in breast cancer. Cancer Cell 8: 227-239.
    • (2005) Cancer Cell , vol.8 , pp. 227-239
    • Schardt, J.A.1    Meyer, M.2    Hartmann, C.H.3    Schubert, F.4    Schmidt-Kittler, O.5
  • 13
    • 0037206022 scopus 로고    scopus 로고
    • Genetic heterogeneity of single disseminated tumour cells in minimal residual cancer
    • Klein CA, Blankenstein TJ, Schmidt-Kittler O, Petronio M, Polzer B, et al. (2002) Genetic heterogeneity of single disseminated tumour cells in minimal residual cancer. Lancet 360: 683-689.
    • (2002) Lancet , vol.360 , pp. 683-689
    • Klein, C.A.1    Blankenstein, T.J.2    Schmidt-Kittler, O.3    Petronio, M.4    Polzer, B.5
  • 14
    • 41649098379 scopus 로고    scopus 로고
    • Breast cancer metastases are molecularly distinct from their primary tumors
    • Vecchi M, Confalonieri S, Nuciforo P, Vigano MA, Capra M, et al. (2008) Breast cancer metastases are molecularly distinct from their primary tumors. Oncogene 27: 2148-2158.
    • (2008) Oncogene , vol.27 , pp. 2148-2158
    • Vecchi, M.1    Confalonieri, S.2    Nuciforo, P.3    Vigano, M.A.4    Capra, M.5
  • 16
    • 77951139631 scopus 로고    scopus 로고
    • Genome remodelling in a basal-like breast cancer metastasis and xenograft
    • Ding L, Ellis MJ, Li S, Larson DE, Chen K, et al. (2010) Genome remodelling in a basal-like breast cancer metastasis and xenograft. Nature 464: 999-1005.
    • (2010) Nature , vol.464 , pp. 999-1005
    • Ding, L.1    Ellis, M.J.2    Li, S.3    Larson, D.E.4    Chen, K.5
  • 17
    • 0037226593 scopus 로고    scopus 로고
    • A molecular signature of metastasis in primary solid tumors
    • Ramaswamy S, Ross KN, Lander ES, Golub TR, (2003) A molecular signature of metastasis in primary solid tumors. Nat Genet 33: 49-54.
    • (2003) Nat Genet , vol.33 , pp. 49-54
    • Ramaswamy, S.1    Ross, K.N.2    Lander, E.S.3    Golub, T.R.4
  • 19
    • 77950809059 scopus 로고    scopus 로고
    • A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations
    • Sharma SV, Lee DY, Li B, Quinlan MP, Takahashi F, et al. (2010) A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations. Cell 141: 69-80.
    • (2010) Cell , vol.141 , pp. 69-80
    • Sharma, S.V.1    Lee, D.Y.2    Li, B.3    Quinlan, M.P.4    Takahashi, F.5
  • 21
    • 67649300721 scopus 로고    scopus 로고
    • Genes that mediate breast cancer metastasis to the brain
    • Bos PD, Zhang XH, Nadal C, Shu W, Gomis RR, et al. (2009) Genes that mediate breast cancer metastasis to the brain. Nature 459: 1005-1009.
    • (2009) Nature , vol.459 , pp. 1005-1009
    • Bos, P.D.1    Zhang, X.H.2    Nadal, C.3    Shu, W.4    Gomis, R.R.5
  • 22
    • 23144461051 scopus 로고    scopus 로고
    • Genes that mediate breast cancer metastasis to lung
    • Minn AJ, Gupta GP, Siegel PM, Bos PD, Shu W, et al. (2005) Genes that mediate breast cancer metastasis to lung. Nature 436: 518-524.
    • (2005) Nature , vol.436 , pp. 518-524
    • Minn, A.J.1    Gupta, G.P.2    Siegel, P.M.3    Bos, P.D.4    Shu, W.5
  • 23
    • 0017704436 scopus 로고
    • Metastasis results from preexisting variant cells within a malignant tumor
    • Fidler IJ, Kripke ML, (1977) Metastasis results from preexisting variant cells within a malignant tumor. Science 197: 893-895.
    • (1977) Science , vol.197 , pp. 893-895
    • Fidler, I.J.1    Kripke, M.L.2
  • 24
    • 17844406154 scopus 로고    scopus 로고
    • Expression profiling of primary tumors and matched lymphatic and lung metastases in a xenogeneic breast cancer model
    • Montel V, Huang TY, Mose E, Pestonjamasp K, Tarin D, (2005) Expression profiling of primary tumors and matched lymphatic and lung metastases in a xenogeneic breast cancer model. Am J Pathol 166: 1565-1579.
    • (2005) Am J Pathol , vol.166 , pp. 1565-1579
    • Montel, V.1    Huang, T.Y.2    Mose, E.3    Pestonjamasp, K.4    Tarin, D.5
  • 25
    • 0038488950 scopus 로고    scopus 로고
    • A multigenic program mediating breast cancer metastasis to bone
    • Kang Y, Siegel PM, Shu W, Drobnjak M, Kakonen SM, et al. (2003) A multigenic program mediating breast cancer metastasis to bone. Cancer Cell 3: 537-549.
    • (2003) Cancer Cell , vol.3 , pp. 537-549
    • Kang, Y.1    Siegel, P.M.2    Shu, W.3    Drobnjak, M.4    Kakonen, S.M.5
  • 26
    • 84864285223 scopus 로고    scopus 로고
    • RNA sequencing of pancreatic circulating tumour cells implicates WNT signalling in metastasis
    • Yu M, Ting DT, Stott SL, Wittner BS, Ozsolak F, et al. (2012) RNA sequencing of pancreatic circulating tumour cells implicates WNT signalling in metastasis. Nature 487: 510-513.
    • (2012) Nature , vol.487 , pp. 510-513
    • Yu, M.1    Ting, D.T.2    Stott, S.L.3    Wittner, B.S.4    Ozsolak, F.5
  • 27
    • 0142244181 scopus 로고    scopus 로고
    • Progression to malignancy in the polyoma middle T oncoprotein mouse breast cancer model provides a reliable model for human diseases
    • Lin EY, Jones JG, Li P, Zhu L, Whitney KD, et al. (2003) Progression to malignancy in the polyoma middle T oncoprotein mouse breast cancer model provides a reliable model for human diseases. Am J Pathol 163: 2113-2126.
    • (2003) Am J Pathol , vol.163 , pp. 2113-2126
    • Lin, E.Y.1    Jones, J.G.2    Li, P.3    Zhu, L.4    Whitney, K.D.5
  • 28
    • 0026587657 scopus 로고
    • Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease
    • Guy CT, Cardiff RD, Muller WJ, (1992) Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease. Mol Cell Biol 12: 954-961.
    • (1992) Mol Cell Biol , vol.12 , pp. 954-961
    • Guy, C.T.1    Cardiff, R.D.2    Muller, W.J.3
  • 29
    • 33845867158 scopus 로고    scopus 로고
    • Polyoma and SV40 proteins differentially regulate PP2A to activate distinct cellular signaling pathways involved in growth control
    • Rodriguez-Viciana P, Collins C, Fried M, (2006) Polyoma and SV40 proteins differentially regulate PP2A to activate distinct cellular signaling pathways involved in growth control. Proc Natl Acad Sci U S A 103: 19290-19295.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 19290-19295
    • Rodriguez-Viciana, P.1    Collins, C.2    Fried, M.3
  • 30
    • 34548863946 scopus 로고    scopus 로고
    • Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors
    • Herschkowitz JI, Simin K, Weigman VJ, Mikaelian I, Usary J, et al. (2007) Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors. Genome Biol 8: R76.
    • (2007) Genome Biol , vol.8
    • Herschkowitz, J.I.1    Simin, K.2    Weigman, V.J.3    Mikaelian, I.4    Usary, J.5
  • 31
    • 38549131901 scopus 로고    scopus 로고
    • GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model
    • Kouros-Mehr H, Bechis SK, Slorach EM, Littlepage LE, Egeblad M, et al. (2008) GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model. Cancer Cell 13: 141-152.
    • (2008) Cancer Cell , vol.13 , pp. 141-152
    • Kouros-Mehr, H.1    Bechis, S.K.2    Slorach, E.M.3    Littlepage, L.E.4    Egeblad, M.5
  • 32
    • 35748949257 scopus 로고    scopus 로고
    • A comparison of background correction methods for two-colour microarrays
    • Ritchie ME, Silver J, Oshlack A, Holmes M, Diyagama D, et al. (2007) A comparison of background correction methods for two-colour microarrays. Bioinformatics 23: 2700-2707.
    • (2007) Bioinformatics , vol.23 , pp. 2700-2707
    • Ritchie, M.E.1    Silver, J.2    Oshlack, A.3    Holmes, M.4    Diyagama, D.5
  • 33
    • 33745696736 scopus 로고    scopus 로고
    • Toxicity and health-related quality of life in breast cancer patients receiving adjuvant docetaxel, doxorubicin, cyclophosphamide (TAC) or 5-fluorouracil, doxorubicin and cyclophosphamide (FAC): impact of adding primary prophylactic granulocyte-colony stimulating factor to the TAC regimen
    • Martin M, Lluch A, Segui MA, Ruiz A, Ramos M, et al. (2006) Toxicity and health-related quality of life in breast cancer patients receiving adjuvant docetaxel, doxorubicin, cyclophosphamide (TAC) or 5-fluorouracil, doxorubicin and cyclophosphamide (FAC): impact of adding primary prophylactic granulocyte-colony stimulating factor to the TAC regimen. Ann Oncol 17: 1205-1212.
    • (2006) Ann Oncol , vol.17 , pp. 1205-1212
    • Martin, M.1    Lluch, A.2    Segui, M.A.3    Ruiz, A.4    Ramos, M.5
  • 34
    • 34547742663 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 1 in breast cancer: analysis with tissue microarray
    • Sheen-Chen SM, Huang CC, Tang RP, Yang CH, Chou FF, et al. (2007) Signal transducer and activator of transcription 1 in breast cancer: analysis with tissue microarray. Anticancer Res 27: 2481-2486.
    • (2007) Anticancer Res , vol.27 , pp. 2481-2486
    • Sheen-Chen, S.M.1    Huang, C.C.2    Tang, R.P.3    Yang, C.H.4    Chou, F.F.5
  • 35
    • 1242319531 scopus 로고    scopus 로고
    • STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells
    • Khodarev NN, Beckett M, Labay E, Darga T, Roizman B, et al. (2004) STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells. Proc Natl Acad Sci U S A 101: 1714-1719.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 1714-1719
    • Khodarev, N.N.1    Beckett, M.2    Labay, E.3    Darga, T.4    Roizman, B.5
  • 36
    • 67149111590 scopus 로고    scopus 로고
    • STAT1 pathway mediates amplification of metastatic potential and resistance to therapy
    • Khodarev NN, Roach P, Pitroda SP, Golden DW, Bhayani M, et al. (2009) STAT1 pathway mediates amplification of metastatic potential and resistance to therapy. PLoS One 4: e5821.
    • (2009) PLoS One , vol.4
    • Khodarev, N.N.1    Roach, P.2    Pitroda, S.P.3    Golden, D.W.4    Bhayani, M.5
  • 37
    • 21044456453 scopus 로고    scopus 로고
    • STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage
    • Townsend PA, Cragg MS, Davidson SM, McCormick J, Barry S, et al. (2005) STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage. J Cell Sci 118: 1629-1639.
    • (2005) J Cell Sci , vol.118 , pp. 1629-1639
    • Townsend, P.A.1    Cragg, M.S.2    Davidson, S.M.3    McCormick, J.4    Barry, S.5
  • 38
    • 0028923658 scopus 로고
    • Elevated levels of members of the STAT family of transcription factors in breast carcinoma nuclear extracts
    • Watson CJ, Miller WR, (1995) Elevated levels of members of the STAT family of transcription factors in breast carcinoma nuclear extracts. Br J Cancer 71: 840-844.
    • (1995) Br J Cancer , vol.71 , pp. 840-844
    • Watson, C.J.1    Miller, W.R.2
  • 39
    • 7244245445 scopus 로고    scopus 로고
    • Roles and regulation of stat family transcription factors in human breast cancer
    • Clevenger CV, (2004) Roles and regulation of stat family transcription factors in human breast cancer. Am J Pathol 165: 1449-1460.
    • (2004) Am J Pathol , vol.165 , pp. 1449-1460
    • Clevenger, C.V.1
  • 41
    • 9644310201 scopus 로고    scopus 로고
    • Molecular portraits of breast cancer: tumour subtypes as distinct disease entities
    • Sorlie T, (2004) Molecular portraits of breast cancer: tumour subtypes as distinct disease entities. Eur J Cancer 40: 2667-2675.
    • (2004) Eur J Cancer , vol.40 , pp. 2667-2675
    • Sorlie, T.1
  • 42
    • 33745834662 scopus 로고    scopus 로고
    • Distinct molecular mechanisms underlying clinically relevant subtypes of breast cancer: gene expression analyses across three different platforms
    • Sorlie T, Wang Y, Xiao C, Johnsen H, Naume B, et al. (2006) Distinct molecular mechanisms underlying clinically relevant subtypes of breast cancer: gene expression analyses across three different platforms. BMC Genomics 7: 127.
    • (2006) BMC Genomics , vol.7 , pp. 127
    • Sorlie, T.1    Wang, Y.2    Xiao, C.3    Johnsen, H.4    Naume, B.5
  • 43
    • 34250652449 scopus 로고    scopus 로고
    • Strong time dependence of the 76-gene prognostic signature for node-negative breast cancer patients in the TRANSBIG multicenter independent validation series
    • Desmedt C, Piette F, Loi S, Wang Y, Lallemand F, et al. (2007) Strong time dependence of the 76-gene prognostic signature for node-negative breast cancer patients in the TRANSBIG multicenter independent validation series. Clin Cancer Res 13: 3207-3214.
    • (2007) Clin Cancer Res , vol.13 , pp. 3207-3214
    • Desmedt, C.1    Piette, F.2    Loi, S.3    Wang, Y.4    Lallemand, F.5
  • 44
    • 33845209913 scopus 로고    scopus 로고
    • A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes
    • Neve RM, Chin K, Fridlyand J, Yeh J, Baehner FL, et al. (2006) A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell 10: 515-527.
    • (2006) Cancer Cell , vol.10 , pp. 515-527
    • Neve, R.M.1    Chin, K.2    Fridlyand, J.3    Yeh, J.4    Baehner, F.L.5
  • 45
    • 33845191779 scopus 로고    scopus 로고
    • Genomic and transcriptional aberrations linked to breast cancer pathophysiologies
    • Chin K, DeVries S, Fridlyand J, Spellman PT, Roydasgupta R, et al. (2006) Genomic and transcriptional aberrations linked to breast cancer pathophysiologies. Cancer Cell 10: 529-541.
    • (2006) Cancer Cell , vol.10 , pp. 529-541
    • Chin, K.1    DeVries, S.2    Fridlyand, J.3    Spellman, P.T.4    Roydasgupta, R.5
  • 46
    • 0042838307 scopus 로고    scopus 로고
    • Breast cancer classification and prognosis based on gene expression profiles from a population-based study
    • Sotiriou C, Neo SY, McShane LM, Korn EL, Long PM, et al. (2003) Breast cancer classification and prognosis based on gene expression profiles from a population-based study. Proc Natl Acad Sci U S A 100: 10393-10398.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 10393-10398
    • Sotiriou, C.1    Neo, S.Y.2    McShane, L.M.3    Korn, E.L.4    Long, P.M.5
  • 47
    • 79959956046 scopus 로고    scopus 로고
    • The JAK2/STAT3 signaling pathway is required for growth of CD44(+)CD24(-) stem cell-like breast cancer cells in human tumors
    • Marotta LL, Almendro V, Marusyk A, Shipitsin M, Schemme J, et al. (2011) The JAK2/STAT3 signaling pathway is required for growth of CD44(+)CD24(-) stem cell-like breast cancer cells in human tumors. J Clin Invest 121: 2723-2735.
    • (2011) J Clin Invest , vol.121 , pp. 2723-2735
    • Marotta, L.L.1    Almendro, V.2    Marusyk, A.3    Shipitsin, M.4    Schemme, J.5
  • 48
    • 34248545443 scopus 로고    scopus 로고
    • Gene expression profiling of breast, prostate, and glioma cells following single versus fractionated doses of radiation
    • Tsai MH, Cook JA, Chandramouli GV, DeGraff W, Yan H, et al. (2007) Gene expression profiling of breast, prostate, and glioma cells following single versus fractionated doses of radiation. Cancer Res 67: 3845-3852.
    • (2007) Cancer Res , vol.67 , pp. 3845-3852
    • Tsai, M.H.1    Cook, J.A.2    Chandramouli, G.V.3    DeGraff, W.4    Yan, H.5
  • 50
    • 57449088412 scopus 로고    scopus 로고
    • An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer
    • Weichselbaum RR, Ishwaran H, Yoon T, Nuyten DS, Baker SW, et al. (2008) An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer. Proc Natl Acad Sci U S A 105: 18490-18495.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 18490-18495
    • Weichselbaum, R.R.1    Ishwaran, H.2    Yoon, T.3    Nuyten, D.S.4    Baker, S.W.5
  • 51
    • 33845384469 scopus 로고    scopus 로고
    • STAT1 signaling is associated with acquired crossresistance to doxorubicin and radiation in myeloma cell lines
    • Fryknas M, Dhar S, Oberg F, Rickardson L, Rydaker M, et al. (2007) STAT1 signaling is associated with acquired crossresistance to doxorubicin and radiation in myeloma cell lines. Int J Cancer 120: 189-195.
    • (2007) Int J Cancer , vol.120 , pp. 189-195
    • Fryknas, M.1    Dhar, S.2    Oberg, F.3    Rickardson, L.4    Rydaker, M.5
  • 52
    • 24944521677 scopus 로고    scopus 로고
    • Identification of molecular mechanisms for cellular drug resistance by combining drug activity and gene expression profiles
    • Rickardson L, Fryknas M, Dhar S, Lovborg H, Gullbo J, et al. (2005) Identification of molecular mechanisms for cellular drug resistance by combining drug activity and gene expression profiles. Br J Cancer 93: 483-492.
    • (2005) Br J Cancer , vol.93 , pp. 483-492
    • Rickardson, L.1    Fryknas, M.2    Dhar, S.3    Lovborg, H.4    Gullbo, J.5
  • 53
    • 33749825228 scopus 로고    scopus 로고
    • Novel role of Stat1 in the development of docetaxel resistance in prostate tumor cells
    • Patterson SG, Wei S, Chen X, Sallman DA, Gilvary DL, et al. (2006) Novel role of Stat1 in the development of docetaxel resistance in prostate tumor cells. Oncogene 25: 6113-6122.
    • (2006) Oncogene , vol.25 , pp. 6113-6122
    • Patterson, S.G.1    Wei, S.2    Chen, X.3    Sallman, D.A.4    Gilvary, D.L.5
  • 54
    • 17444362227 scopus 로고    scopus 로고
    • Identification of genes associated with platinum drug sensitivity and resistance in human ovarian cancer cells
    • Roberts D, Schick J, Conway S, Biade S, Laub PB, et al. (2005) Identification of genes associated with platinum drug sensitivity and resistance in human ovarian cancer cells. Br J Cancer 92: 1149-1158.
    • (2005) Br J Cancer , vol.92 , pp. 1149-1158
    • Roberts, D.1    Schick, J.2    Conway, S.3    Biade, S.4    Laub, P.B.5
  • 55
    • 79956300159 scopus 로고    scopus 로고
    • A novel requirement for Janus kinases as mediators of drug resistance induced by fibroblast growth factor-2 in human cancer cells
    • Carmo CR, Lyons-Lewis J, Seckl MJ, Costa-Pereira AP, (2011) A novel requirement for Janus kinases as mediators of drug resistance induced by fibroblast growth factor-2 in human cancer cells. PLoS One 6: e19861.
    • (2011) PLoS One , vol.6
    • Carmo, C.R.1    Lyons-Lewis, J.2    Seckl, M.J.3    Costa-Pereira, A.P.4
  • 56
    • 77958501473 scopus 로고    scopus 로고
    • DNA damage-mediated induction of a chemoresistant niche
    • Gilbert LA, Hemann MT, (2010) DNA damage-mediated induction of a chemoresistant niche. Cell 143: 355-366.
    • (2010) Cell , vol.143 , pp. 355-366
    • Gilbert, L.A.1    Hemann, M.T.2
  • 57
    • 79958161210 scopus 로고    scopus 로고
    • Deactivation of signal transducer and activator of transcription 3 reverses chemotherapeutics resistance of leukemia cells via down-regulating P-gp
    • Zhang X, Xiao W, Wang L, Tian Z, Zhang J, (2011) Deactivation of signal transducer and activator of transcription 3 reverses chemotherapeutics resistance of leukemia cells via down-regulating P-gp. PLoS One 6: e20965.
    • (2011) PLoS One , vol.6
    • Zhang, X.1    Xiao, W.2    Wang, L.3    Tian, Z.4    Zhang, J.5
  • 58
    • 0037206950 scopus 로고    scopus 로고
    • Resistance to chemotherapy via Stat3-dependent overexpression of Bcl-2 in metastatic breast cancer cells
    • Real PJ, Sierra A, De Juan A, Segovia JC, Lopez-Vega JM, et al. (2002) Resistance to chemotherapy via Stat3-dependent overexpression of Bcl-2 in metastatic breast cancer cells. Oncogene 21: 7611-7618.
    • (2002) Oncogene , vol.21 , pp. 7611-7618
    • Real, P.J.1    Sierra, A.2    De Juan, A.3    Segovia, J.C.4    Lopez-Vega, J.M.5
  • 59
    • 0033036097 scopus 로고    scopus 로고
    • Serum interleukin-6 levels correlate to tumor progression and prognosis in metastatic breast carcinoma
    • Zhang GJ, Adachi I, (1999) Serum interleukin-6 levels correlate to tumor progression and prognosis in metastatic breast carcinoma. Anticancer Res 19: 1427-1432.
    • (1999) Anticancer Res , vol.19 , pp. 1427-1432
    • Zhang, G.J.1    Adachi, I.2
  • 60
    • 0037455841 scopus 로고    scopus 로고
    • Circulating interleukin-6 predicts survival in patients with metastatic breast cancer
    • Salgado R, Junius S, Benoy I, Van Dam P, Vermeulen P, et al. (2003) Circulating interleukin-6 predicts survival in patients with metastatic breast cancer. Int J Cancer 103: 642-646.
    • (2003) Int J Cancer , vol.103 , pp. 642-646
    • Salgado, R.1    Junius, S.2    Benoy, I.3    Van Dam, P.4    Vermeulen, P.5
  • 61
    • 34447506658 scopus 로고    scopus 로고
    • Oncogenic Ras-induced secretion of IL6 is required for tumorigenesis
    • Ancrile B, Lim KH, Counter CM, (2007) Oncogenic Ras-induced secretion of IL6 is required for tumorigenesis. Genes Dev 21: 1714-1719.
    • (2007) Genes Dev , vol.21 , pp. 1714-1719
    • Ancrile, B.1    Lim, K.H.2    Counter, C.M.3
  • 62
    • 0035799531 scopus 로고    scopus 로고
    • Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells
    • Garcia R, Bowman TL, Niu G, Yu H, Minton S, et al. (2001) Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells. Oncogene 20: 2499-2513.
    • (2001) Oncogene , vol.20 , pp. 2499-2513
    • Garcia, R.1    Bowman, T.L.2    Niu, G.3    Yu, H.4    Minton, S.5
  • 63
    • 33947414063 scopus 로고    scopus 로고
    • Significance of interleukin-6 (IL-6) in breast cancer (review)
    • Knupfer H, Preiss R, (2007) Significance of interleukin-6 (IL-6) in breast cancer (review). Breast Cancer Res Treat 102: 129-135.
    • (2007) Breast Cancer Res Treat , vol.102 , pp. 129-135
    • Knupfer, H.1    Preiss, R.2
  • 65
    • 70949094349 scopus 로고    scopus 로고
    • The JAK2 inhibitor AZD1480 potently blocks Stat3 signaling and oncogenesis in solid tumors
    • Hedvat M, Huszar D, Herrmann A, Gozgit JM, Schroeder A, et al. (2009) The JAK2 inhibitor AZD1480 potently blocks Stat3 signaling and oncogenesis in solid tumors. Cancer Cell 16: 487-497.
    • (2009) Cancer Cell , vol.16 , pp. 487-497
    • Hedvat, M.1    Huszar, D.2    Herrmann, A.3    Gozgit, J.M.4    Schroeder, A.5
  • 66
    • 84867919330 scopus 로고    scopus 로고
    • Targeting Notch, a key pathway for ovarian cancer stem cells, sensitizes tumors to platinum therapy
    • McAuliffe SM, Morgan SL, Wyant GA, Tran LT, Muto KW, et al. (2012) Targeting Notch, a key pathway for ovarian cancer stem cells, sensitizes tumors to platinum therapy. Proc Natl Acad Sci U S A 109: E2939-2948.
    • (2012) Proc Natl Acad Sci U S A , vol.109
    • McAuliffe, S.M.1    Morgan, S.L.2    Wyant, G.A.3    Tran, L.T.4    Muto, K.W.5
  • 68
    • 84859893371 scopus 로고    scopus 로고
    • Histone methylation: a dynamic mark in health, disease and inheritance
    • Greer EL, Shi Y, (2012) Histone methylation: a dynamic mark in health, disease and inheritance. Nat Rev Genet 13: 343-357.
    • (2012) Nat Rev Genet , vol.13 , pp. 343-357
    • Greer, E.L.1    Shi, Y.2
  • 69
    • 77049099785 scopus 로고    scopus 로고
    • Histone methyltransferases in cancer
    • Albert M, Helin K, (2010) Histone methyltransferases in cancer. Semin Cell Dev Biol 21: 209-220.
    • (2010) Semin Cell Dev Biol , vol.21 , pp. 209-220
    • Albert, M.1    Helin, K.2
  • 70
    • 84864434739 scopus 로고    scopus 로고
    • Emerging epigenetic targets and therapies in cancer medicine
    • Popovic R, Licht JD, (2012) Emerging epigenetic targets and therapies in cancer medicine. Cancer Discov 2: 405-413.
    • (2012) Cancer Discov , vol.2 , pp. 405-413
    • Popovic, R.1    Licht, J.D.2
  • 71
    • 65149084552 scopus 로고    scopus 로고
    • Crosstalk between histone modifications during the DNA damage response
    • van Attikum H, Gasser SM, (2009) Crosstalk between histone modifications during the DNA damage response. Trends Cell Biol 19: 207-217.
    • (2009) Trends Cell Biol , vol.19 , pp. 207-217
    • van Attikum, H.1    Gasser, S.M.2
  • 72
    • 84879421605 scopus 로고    scopus 로고
    • The histone methyltransferase MMSET/WHSC1 activates TWIST1 to promote an epithelial-mesenchymal transition and invasive properties of prostate cancer
    • Ezponda T, Popovic R, Shah MY, Martinez-Garcia E, Zheng Y, et al. (2012) The histone methyltransferase MMSET/WHSC1 activates TWIST1 to promote an epithelial-mesenchymal transition and invasive properties of prostate cancer. Oncogene.
    • (2012) Oncogene
    • Ezponda, T.1    Popovic, R.2    Shah, M.Y.3    Martinez-Garcia, E.4    Zheng, Y.5
  • 73
    • 78049307486 scopus 로고    scopus 로고
    • H3K9 histone methyltransferase G9a promotes lung cancer invasion and metastasis by silencing the cell adhesion molecule Ep-CAM
    • Chen MW, Hua KT, Kao HJ, Chi CC, Wei LH, et al. (2010) H3K9 histone methyltransferase G9a promotes lung cancer invasion and metastasis by silencing the cell adhesion molecule Ep-CAM. Cancer Res 70: 7830-7840.
    • (2010) Cancer Res , vol.70 , pp. 7830-7840
    • Chen, M.W.1    Hua, K.T.2    Kao, H.J.3    Chi, C.C.4    Wei, L.H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.