Somatic Hypermutation-Induced Changes in the Structure and Dynamics of HIV-1 Broadly Neutralizing Antibodies

Structure

Volumn 24, Issue 8, 2016, Pages 1346-1357

  Davenport, Thaddeus M ^a   Gorman, Jason ^b   Joyce, M Gordon ^b   Zhou, Tongqing ^b   Soto, Cinque ^b   Guttman, Miklos ^a   Moquin, Stephanie ^b   Yang, Yongping ^b   Zhang, Baoshan ^b   Doria Rose, Nicole A ^b   Hu, Shiu Lok ^a   Mascola, John R ^b   Kwong, Peter D ^b   Lee, Kelly K ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENVELOPE PROTEIN; GLYCOPROTEIN; HUMAN IMMUNODEFICIENCY VIRUS PROTEIN; IMMUNOGLOBULIN F(AB) FRAGMENT; NEUTRALIZING ANTIBODY; VIRUS ANTIBODY;

ANTIBODY COMBINING SITE; ANTIBODY STRUCTURE; ARTICLE; CONTROLLED STUDY; DEUTERIUM HYDROGEN EXCHANGE; DYNAMICS; HUMAN IMMUNODEFICIENCY VIRUS 1; LIGHT CHAIN; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; SOMATIC HYPERMUTATION; CHEMISTRY; GENETICS; HUMAN; IMMUNOLOGY; MOLECULAR DYNAMICS;

ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; HIV-1; HUMANS; MOLECULAR DYNAMICS SIMULATION; SOMATIC HYPERMUTATION, IMMUNOGLOBULIN;

EID: 84979741951     PISSN: 09692126     EISSN: 18784186     Source Type: Journal    
DOI: 10.1016/j.str.2016.06.012     Document Type: Article

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