Enhanced resolution of experimental ards through il-4-mediated lung macrophage reprogramming

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 310, Issue 8, 2016, Pages L733-L746

  D'Alessio F R ^a   Craig, J M ^b   Singer, B D ^a   Files, D C ^c   Mock, J R ^a   Garibaldi, B T ^a   Fallica, J ^a   Tripathi, A ^a   Mandke, P ^a   Gans, J H ^a   Limjunyawong, N ^b   Sidhaye, V K ^a   Heller, N M ^d   Mitzner, W ^b   King, L S ^a   Aggarwal, N R ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^c WAKE FOREST SCHOOL OF MEDICINE   (United States)

^d JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Acute lung injury; ARDS; Interleukin 4; Macrophage; Resolution

Indexed keywords

ARGONAUTE 1 PROTEIN; BACTERIUM LIPOPOLYSACCHARIDE; CYTOKINE; DECTIN 1; FIZZ1 PROTEIN; INTERLEUKIN 4; INTERLEUKIN 4 ANTIBODY; MACROPHAGE MANNOSE RECEPTOR; MANNOSE RECEPTOR; PROTEIN M2; RECOMBINANT INTERLEUKIN 4; STAT6 PROTEIN; UNCLASSIFIED DRUG; YM1 PROTEIN; LIPOPOLYSACCHARIDE;

ADULT RESPIRATORY DISTRESS SYNDROME; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG EFFICACY; DRUG HALF LIFE; INFLAMMATION; LIPOPOLYSACCHARIDE-INDUCED ACUTE LUNG INJURY; LUNG; LUNG ALVEOLUS MACROPHAGE; LUNG FUNCTION; LUNG PARENCHYMA; MALE; MEDIATOR; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PSEUDOMONAS; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; SURVIVAL RATE; TISSUE REPAIR; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; IMMUNOLOGY; KNOCKOUT MOUSE; MACROPHAGE ACTIVATION; PHYSIOLOGY; PRECLINICAL STUDY; REGULATORY T LYMPHOCYTE; RESPIRATORY DISTRESS SYNDROME, ADULT;

ANIMALS; DRUG EVALUATION, PRECLINICAL; INTERLEUKIN-4; LIPOPOLYSACCHARIDES; MACROPHAGE ACTIVATION; MACROPHAGES, ALVEOLAR; MALE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; RESPIRATORY DISTRESS SYNDROME, ADULT; T-LYMPHOCYTES, REGULATORY;

EID: 84979631267     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00419.2015     Document Type: Article

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