메뉴 건너뛰기




Volumn 192, Issue 9, 2014, Pages 4453-4464

Immunological priming requires regulatory T Cells and IL-10-producing macrophages to accelerate resolution from severe lung inflammation

Author keywords

[No Author keywords available]

Indexed keywords

CPG OLIGONUCLEOTIDE; INTERLEUKIN 10; LIPOPOLYSACCHARIDE; OLIGONUCLEOTIDE; UNCLASSIFIED DRUG;

EID: 84899542322     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1400146     Document Type: Article
Times cited : (36)

References (86)
  • 1
    • 80052305941 scopus 로고    scopus 로고
    • The Toll-like receptor 4 agonist monophosphoryl lipid a augments innate host resistance to systemic bacterial infection
    • Romero, C. D., T. K. Varma, J. B. Hobbs, A. Reyes, B. Driver, and E. R. Sherwood. 2011. The Toll-like receptor 4 agonist monophosphoryl lipid a augments innate host resistance to systemic bacterial infection. Infect. Immun. 79: 3576-3587
    • (2011) Infect. Immun , vol.79 , pp. 3576-3587
    • Romero, C.D.1    Varma, T.K.2    Hobbs, J.B.3    Reyes, A.4    Driver, B.5    Sherwood, E.R.6
  • 5
    • 0023733047 scopus 로고
    • Monocyte retention and migration in pulmonary inflammation: Requirement for neutrophils
    • Doherty, D. E., G. P. Downey, G. S. Worthen, C. Haslett, and P. M. Henson. 1988. Monocyte retention and migration in pulmonary inflammation: Requirement for neutrophils. Lab. Invest. 59: 200-213
    • (1988) Lab. Invest , vol.59 , pp. 200-213
    • Doherty, D.E.1    Downey, G.P.2    Worthen, G.S.3    Haslett, C.4    Henson, P.M.5
  • 6
    • 84864015813 scopus 로고    scopus 로고
    • Acute lung injury: How macrophages orchestrate resolution of inflammation and tissue repair
    • Herold, S., K. Mayer, and J. Lohmeyer. 2011. Acute lung injury: How macrophages orchestrate resolution of inflammation and tissue repair. Front. Immunol. 2: 65
    • (2011) Front. Immunol , vol.2 , pp. 65
    • Herold, S.1    Mayer, K.2    Lohmeyer, J.3
  • 7
    • 0037180812 scopus 로고    scopus 로고
    • Points of control in inflammation
    • Nathan, C. 2002. Points of control in inflammation. Nature 420: 846-852
    • (2002) Nature , vol.420 , pp. 846-852
    • Nathan, C.1
  • 8
    • 0024378214 scopus 로고
    • Alveolar macrophage elimination in vivo is associated with an increase in pulmonary immune response in mice
    • Thepen, T., N. Van Rooijen, and G. Kraal. 1989. Alveolar macrophage elimination in vivo is associated with an increase in pulmonary immune response in mice. J. Exp. Med. 170: 499-509
    • (1989) J. Exp. Med , vol.170 , pp. 499-509
    • Thepen, T.1    Van Rooijen, N.2    Kraal, G.3
  • 9
    • 0037033073 scopus 로고    scopus 로고
    • Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the Toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction
    • Latz, E., A. Visintin, E. Lien, K. A. Fitzgerald, B. G. Monks, E. A. Kurt-Jones, D. T. Golenbock, and T. Espevik. 2002. Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the Toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction. J. Biol. Chem. 277: 47834-47843
    • (2002) J. Biol. Chem , vol.277 , pp. 47834-47843
    • Latz, E.1    Visintin, A.2    Lien, E.3    Fitzgerald, K.A.4    Monks, B.G.5    Kurt-Jones, E.A.6    Golenbock, D.T.7    Espevik, T.8
  • 10
    • 0242552753 scopus 로고    scopus 로고
    • Molecular mechanisms of macrophage activation and deactivation by lipopolysaccharide: Roles of the receptor complex
    • Fujihara, M., M. Muroi, K. Tanamoto, T. Suzuki, H. Azuma, and H. Ikeda. 2003. Molecular mechanisms of macrophage activation and deactivation by lipopolysaccharide: Roles of the receptor complex. Pharmacol. Ther. 100: 171-194
    • (2003) Pharmacol. Ther , vol.100 , pp. 171-194
    • Fujihara, M.1    Muroi, M.2    Tanamoto, K.3    Suzuki, T.4    Azuma, H.5    Ikeda, H.6
  • 11
    • 70349559403 scopus 로고    scopus 로고
    • Endotoxin tolerance: New mechanisms, molecules and clinical significance
    • Biswas, S. K., and E. Lopez-Collazo. 2009. Endotoxin tolerance: New mechanisms, molecules and clinical significance. Trends Immunol. 30: 475-487
    • (2009) Trends Immunol , vol.30 , pp. 475-487
    • Biswas, S.K.1    Lopez-Collazo, E.2
  • 13
    • 0032734726 scopus 로고    scopus 로고
    • Clinical aspects: From systemic inflammation to immunoparalysis
    • Volk, H. D., P. Reinke, and W. D. Döcke. 2000. Clinical aspects: From systemic inflammation to immunoparalysis. Chem. Immunol. 74: 162-177
    • (2000) Chem Immunol , vol.74 , pp. 162-177
    • Volk, H.D.1    Reinke, P.2    Döcke, W.D.3
  • 14
    • 68049084831 scopus 로고    scopus 로고
    • Microcirculation and vascular reactivity during endotoxemia and endotoxin tolerance in humans
    • Draisma, A., R. Bemelmans, J. G.Van Der Hoeven, P. Spronk, and P. Pickkers. 2009. Microcirculation and vascular reactivity during endotoxemia and endotoxin tolerance in humans. Shock 31: 581-585
    • (2009) Shock , vol.31 , pp. 581-585
    • Draisma, A.1    Bemelmans, R.2    Van Der Hoeven, J.G.3    Spronk, P.4    Pickkers, P.5
  • 17
    • 42149083307 scopus 로고    scopus 로고
    • CCR2+ monocyte-derived dendritic cells and exudate macrophages produce influenzainduced pulmonary immune pathology and mortality
    • Lin, K. L., Y. Suzuki, H. Nakano, E. Ramsburg, and M. D. Gunn. 2008. CCR2+ monocyte-derived dendritic cells and exudate macrophages produce influenzainduced pulmonary immune pathology and mortality. J. Immunol. 180: 2562-2572
    • (2008) J. Immunol , vol.180 , pp. 2562-2572
    • Lin, K.L.1    Suzuki, Y.2    Nakano, H.3    Ramsburg, E.4    Gunn, M.D.5
  • 19
    • 0038283161 scopus 로고    scopus 로고
    • Interleukin-10 therapy-review of a new approach
    • Asadullah, K., W. Sterry, and H. D. Volk. 2003. Interleukin-10 therapy-review of a new approach. Pharmacol. Rev. 55: 241-269
    • (2003) Pharmacol. Rev , vol.55 , pp. 241-269
    • Asadullah, K.1    Sterry, W.2    Volk, H.D.3
  • 22
    • 0028815553 scopus 로고
    • Interleukin-10 is a central regulator of the response to LPS in murine models of endotoxic shock and the Shwartzman reaction but not endotoxin tolerance
    • Berg, D. J., R. Kuhn, K. Rajewsky, W. Muller, S. Menon, N. Davidson, G. Grunig, and D. Rennick. 1995. Interleukin-10 is a central regulator of the response to LPS in murine models of endotoxic shock and the Shwartzman reaction but not endotoxin tolerance. J. Clin. Invest. 96: 2339-2347
    • (1995) J. Clin. Invest , vol.96 , pp. 2339-2347
    • Berg, D.J.1    Kuhn, R.2    Rajewsky, K.3    Muller, W.4    Menon, S.5    Davidson, N.6    Grunig, G.7    Rennick, D.8
  • 23
    • 0036721716 scopus 로고    scopus 로고
    • Shaping gene expression in activated and resting primary macrophages by IL-10
    • Lang, R., D. Patel, J. J. Morris, R. L. Rutschman, and P. J. Murray. 2002. Shaping gene expression in activated and resting primary macrophages by IL-10. J. Immunol. 169: 2253-2263
    • (2002) J. Immunol , vol.169 , pp. 2253-2263
    • Lang, R.1    Patel, D.2    Morris, J.J.3    Rutschman, R.L.4    Murray, P.J.5
  • 26
    • 61449243725 scopus 로고    scopus 로고
    • Macrophage phagocytosis of apoptotic neutrophils is critically regulated by the opposing actions of pro-inflammatory and anti-inflammatory agents: Key role for TNF-A
    • Michlewska, S., I. Dransfield, I. L. Megson, and A. G. Rossi. 2009. Macrophage phagocytosis of apoptotic neutrophils is critically regulated by the opposing actions of pro-inflammatory and anti-inflammatory agents: Key role for TNF-a. FASEB J. 23: 844-854
    • (2009) FASEB J. , vol.23 , pp. 844-854
    • Michlewska, S.1    Dransfield, I.2    Megson, I.L.3    Rossi, A.G.4
  • 28
    • 0037083341 scopus 로고    scopus 로고
    • Lipopolysaccharide induces rapid production of IL-10 by monocytes in the presence of apoptotic neutrophils
    • Byrne, A., and D. J. Reen. 2002. Lipopolysaccharide induces rapid production of IL-10 by monocytes in the presence of apoptotic neutrophils. J. Immunol. 168: 1968-1977
    • (2002) J. Immunol , vol.168 , pp. 1968-1977
    • Byrne, A.1    Reen, D.J.2
  • 29
    • 0035337139 scopus 로고    scopus 로고
    • Reversing lipopolysaccharide toxicity by ligating the macrophage Fcg receptors
    • Gerber, J. S., and D. M. Mosser. 2001. Reversing lipopolysaccharide toxicity by ligating the macrophage Fcg receptors. J. Immunol. 166: 6861-6868
    • (2001) J. Immunol , vol.166 , pp. 6861-6868
    • Gerber, J.S.1    Mosser, D.M.2
  • 30
    • 34948886712 scopus 로고    scopus 로고
    • Adaptive immune cells temper initial innate responses
    • Kim, K. D., J. Zhao, S. Auh, X. Yang, P. Du, H. Tang, and Y. X. Fu. 2007. Adaptive immune cells temper initial innate responses. Nat. Med. 13: 1248-1252
    • (2007) Nat. Med , vol.13 , pp. 1248-1252
    • Kim, K.D.1    Zhao, J.2    Auh, S.3    Yang, X.4    Du, P.5    Tang, H.6    Fu, Y.X.7
  • 31
    • 78651062856 scopus 로고    scopus 로고
    • Phenotypic and functional switch of macrophages induced by regulatory CD4+CD25+ T cells in mice
    • Liu, G., H. Ma, L. Qiu, L. Li, Y. Cao, J. Ma, and Y. Zhao. 2011. Phenotypic and functional switch of macrophages induced by regulatory CD4+CD25+ T cells in mice. Immunol. Cell Biol. 89: 130-142
    • (2011) Immunol. Cell Biol , vol.89 , pp. 130-142
    • Liu, G.1    Ma, H.2    Qiu, L.3    Li, L.4    Cao, Y.5    Ma, J.6    Zhao, Y.7
  • 35
    • 84859427531 scopus 로고    scopus 로고
    • Ex vivo expansion of human Tregs by rabbit ATG is dependent on intact STAT3-signaling in CD4+ T cells and requires the presence of monocytes
    • Boenisch, O., M. Lopez, W. Elyaman, C. N. Magee, U. Ahmad, and N. Najafian. 2012. Ex vivo expansion of human Tregs by rabbit ATG is dependent on intact STAT3-signaling in CD4+ T cells and requires the presence of monocytes. Am. J. Transplant. 12: 856-866
    • (2012) Am. J. Transplant , vol.12 , pp. 856-866
    • Boenisch, O.1    Lopez, M.2    Elyaman, W.3    Magee, C.N.4    Ahmad, U.5    Najafian, N.6
  • 36
    • 80855138077 scopus 로고    scopus 로고
    • An instructive role of donor macrophages in mixed chimeras in the induction of recipient CD4+ Foxp3+ Treg cells
    • Liu, G., K. Duan, H. Ma, Z. Niu, J. Peng, and Y. Zhao. 2011. An instructive role of donor macrophages in mixed chimeras in the induction of recipient CD4+ Foxp3+ Treg cells. Immunol. Cell Biol. 89: 827-835
    • (2011) Immunol. Cell Biol , vol.89 , pp. 827-835
    • Liu, G.1    Duan, K.2    Ma, H.3    Niu, Z.4    Peng, J.5    Zhao, Y.6
  • 37
    • 84881018661 scopus 로고    scopus 로고
    • Alveolar macrophages contribute to respiratory tolerance by inducing FoxP3 expression in naive T cells
    • Coleman, M. M., D. Ruane, B. Moran, P. J. Dunne, J. Keane, and K. H. Mills. 2013. Alveolar macrophages contribute to respiratory tolerance by inducing FoxP3 expression in naive T cells. Am. J. Respir. Cell Mol. Biol. 48: 773-780
    • (2013) Am. J. Respir. Cell Mol. Biol , vol.48 , pp. 773-780
    • Coleman, M.M.1    Ruane, D.2    Moran, B.3    Dunne, P.J.4    Keane, J.5    Mills, K.H.6
  • 39
    • 33846485153 scopus 로고    scopus 로고
    • Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice
    • Kim, J. M., J. P. Rasmussen, and A. Y. Rudensky. 2007. Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice. Nat. Immunol. 8: 191-197
    • (2007) Nat. Immunol , vol.8 , pp. 191-197
    • Kim, J.M.1    Rasmussen, J.P.2    Rudensky, A.Y.3
  • 41
    • 0028106745 scopus 로고
    • Agarose infiltration improves morphology of cryostat sections of lung
    • Halbower, A. C., R. J. Mason, S. H. Abman, and R. M. Tuder. 1994. Agarose infiltration improves morphology of cryostat sections of lung. Lab. Invest. 71: 149-153
    • (1994) Lab. Invest , vol.71 , pp. 149-153
    • Halbower, A.C.1    Mason, R.J.2    Abman, S.H.3    Tuder, R.M.4
  • 44
    • 0037393128 scopus 로고    scopus 로고
    • The role of apoptosis in acute lung injury
    • Martin, T. R., M. Nakamura, and G. Matute-Bello. 2003. The role of apoptosis in acute lung injury. Crit. Care Med. 31(Suppl. 4): S184-S188
    • (2003) Crit. Care Med , vol.31 , Issue.SUPPL. 4
    • Martin, T.R.1    Nakamura, M.2    Matute-Bello, G.3
  • 46
    • 0141885959 scopus 로고    scopus 로고
    • Science review: Apoptosis in acute lung injury
    • Matute-Bello, G., and T. R. Martin. 2003. Science review: Apoptosis in acute lung injury. Crit. Care 7: 355-358
    • (2003) Crit. Care , vol.7 , pp. 355-358
    • Matute-Bello, G.1    Martin, T.R.2
  • 47
    • 80052510176 scopus 로고    scopus 로고
    • Excessive neutrophils and neutrophil extracellular traps contribute to acute lung injury of influenza pneumonitis
    • Narasaraju, T., E. Yang, R. P. Samy, H. H. Ng, W. P. Poh, A. A. Liew, M. C. Phoon, N. Van Rooijen, and V. T. Chow. 2011. Excessive neutrophils and neutrophil extracellular traps contribute to acute lung injury of influenza pneumonitis. Am. J. Pathol. 179: 199-210
    • (2011) Am. J. Pathol , vol.179 , pp. 199-210
    • Narasaraju, T.1    Yang, E.2    Samy, R.P.3    Ng, H.H.4    Poh, W.P.5    Liew, A.A.6    Phoon, M.C.7    Van Rooijen, N.8    Chow, V.T.9
  • 48
    • 0031950180 scopus 로고    scopus 로고
    • Expression of pro-inflammatory cytokines by flow-sorted alveolar macrophages in severe pneumonia
    • Maus, U., S. Rosseau, U. Knies, W. Seeger, and J. Lohmeyer. 1998. Expression of pro-inflammatory cytokines by flow-sorted alveolar macrophages in severe pneumonia. Eur. Respir. J. 11: 534-541
    • (1998) Eur. Respir. J. , vol.11 , pp. 534-541
    • Maus, U.1    Rosseau, S.2    Knies, U.3    Seeger, W.4    Lohmeyer, J.5
  • 50
    • 0035106745 scopus 로고    scopus 로고
    • Divergent effects of tumor necrosis factor a on apoptosis of human neutrophils
    • Van Den Berg, J. M., S. Weyer, J. J. Weening, D. Roos, and T. W. Kuijpers. 2001. Divergent effects of tumor necrosis factor a on apoptosis of human neutrophils. J. Leukoc. Biol. 69: 467-473
    • (2001) J. Leukoc. Biol , vol.69 , pp. 467-473
    • Van Den Berg, J.M.1    Weyer, S.2    Weening, J.J.3    Roos, D.4    Kuijpers, T.W.5
  • 51
    • 37349117622 scopus 로고    scopus 로고
    • Alveolar interleukin-10 regulates neutrophil apoptosis in severely traumatized patients
    • Turina, M., J. J. Hoth, R. M. Turpen, M. J. Scott, and W. G. Cheadle. 2007. Alveolar interleukin-10 regulates neutrophil apoptosis in severely traumatized patients. J. Trauma 63: 733-739
    • (2007) J. Trauma , vol.63 , pp. 733-739
    • Turina, M.1    Hoth, J.J.2    Turpen, R.M.3    Scott, M.J.4    Cheadle, W.G.5
  • 55
    • 34447128388 scopus 로고    scopus 로고
    • Antiinfective applications of Toll-like receptor 9 agonists
    • Krieg, A. M. 2007. Antiinfective applications of Toll-like receptor 9 agonists. Proc. Am. Thorac. Soc. 4: 289-294
    • (2007) Proc. Am. Thorac. Soc , vol.4 , pp. 289-294
    • Krieg, A.M.1
  • 58
    • 60849117220 scopus 로고    scopus 로고
    • IL-10 administration attenuates pulmonary neutrophil infiltration and alters pulmonary iNOS activation following hemorrhagic shock
    • Kobbe, P., J. Schmidt, B. Stoffels, R. S. ChanthaphaVong, A. J. Bauer, and H. C. Pape. 2009. IL-10 administration attenuates pulmonary neutrophil infiltration and alters pulmonary iNOS activation following hemorrhagic shock. Inflamm. Res. 58: 170-174.
    • (2009) Inflamm. Res , vol.58 , pp. 170-174
    • Kobbe, P.1    Schmidt, J.2    Stoffels, B.3    Chanthaphavong, R.S.4    Bauer, A.J.5    Pape, H.C.6
  • 64
    • 0141910249 scopus 로고    scopus 로고
    • Modulation of neutrophil apoptosis by granulocyte colony-stimulating factor and granulocyte/macrophage colonystimulating factor during the course of acute respiratory distress syndrome
    • Matute-Bello, G., W. C. Liles, F. Radella, II, K. P. Steinberg, J. T. Ruzinski, L. D. Hudson, and T. R. Martin. 2000. Modulation of neutrophil apoptosis by granulocyte colony-stimulating factor and granulocyte/macrophage colonystimulating factor during the course of acute respiratory distress syndrome. Crit. Care Med. 28: 1-7
    • (2000) Crit. Care Med , vol.28 , pp. 1-7
    • Matute-Bello, G.1    Liles, W.C.2    Radella, I.I.F.3    Steinberg, K.P.4    Ruzinski, J.T.5    Hudson, L.D.6    Martin, T.R.7
  • 66
    • 84874062334 scopus 로고    scopus 로고
    • STAT1-regulated lung MDSC-like cells produce IL-10 and efferocytose apoptotic neutrophils with releVance in resolution of bacterial pneumonia
    • Poe, S. L., M. Arora, T. B. Oriss, M. Yarlagadda, K. Isse, A. Khare, D. E. Levy, J. S. Lee, R. K. Mallampalli, Y. R. Chan, et al. 2013. STAT1-regulated lung MDSC-like cells produce IL-10 and efferocytose apoptotic neutrophils with releVance in resolution of bacterial pneumonia. Mucosal Immunol. 6: 189-199
    • (2013) Mucosal Immunol , vol.6 , pp. 189-199
    • Poe, S.L.1    Arora, M.2    Oriss, T.B.3    Yarlagadda, M.4    Isse, K.5    Khare, A.6    Levy, D.E.7    Lee, J.S.8    Mallampalli, R.K.9    Chan, Y.R.10
  • 67
    • 57149107350 scopus 로고    scopus 로고
    • Gene-specific control of the TLR-induced inflammatory response
    • Foster, S. L., and R. Medzhitov. 2009. Gene-specific control of the TLR-induced inflammatory response. Clin. Immunol. 130: 7-15
    • (2009) Clin. Immunol , vol.130 , pp. 7-15
    • Foster, S.L.1    Medzhitov, R.2
  • 68
    • 2342430991 scopus 로고    scopus 로고
    • Molecular mechanisms of endotoxin tolerance
    • Fan, H., and J. A. Cook. 2004. Molecular mechanisms of endotoxin tolerance. J. Endotoxin Res. 10: 71-84
    • (2004) J. Endotoxin Res , vol.10 , pp. 71-84
    • Fan, H.1    Cook, J.A.2
  • 69
    • 0036099755 scopus 로고    scopus 로고
    • Endotoxin tolerance-current concepts in historical perspective
    • Cross, A. S. 2002. Endotoxin tolerance-current concepts in historical perspective. J. Endotoxin Res. 8: 83-98
    • (2002) J. Endotoxin Res , vol.8 , pp. 83-98
    • Cross, A.S.1
  • 70
    • 34250869345 scopus 로고    scopus 로고
    • Bench-to-bedside review: Endotoxin tolerance as a model of leukocyte reprogramming in sepsis
    • Cavaillon, J. M., and M. Adib-Conquy. 2006. Bench-to-bedside review: Endotoxin tolerance as a model of leukocyte reprogramming in sepsis. Crit. Care 10: 233
    • (2006) Crit. Care , vol.10 , pp. 233
    • Cavaillon, J.M.1    Adib-Conquy, M.2
  • 72
    • 0034043956 scopus 로고    scopus 로고
    • Inhibition of lipopolysaccharide-induced signal transduction in endotoxin-tolerized mouse macrophages: Dysregulation of cytokine, chemokine, and toll-like receptor 2 and 4 gene expression
    • Medvedev, A. E., K. M. Kopydlowski, and S. N. Vogel. 2000. Inhibition of lipopolysaccharide-induced signal transduction in endotoxin-tolerized mouse macrophages: Dysregulation of cytokine, chemokine, and Toll-like receptor 2 and 4 gene expression. J. Immunol. 164: 5564-5574
    • (2000) J. Immunol , vol.164 , pp. 5564-5574
    • Medvedev, A.E.1    Kopydlowski, K.M.2    Vogel, S.N.3
  • 73
    • 0036067659 scopus 로고    scopus 로고
    • Toll receptors CD14, and macrophage activation and deactivation by LPS
    • Dobrovolskaia, M. A., and S. N. Vogel. 2002. Toll receptors, CD14, and macrophage activation and deactivation by LPS. Microbes Infect. 4: 903-914
    • (2002) Microbes Infect , vol.4 , pp. 903-914
    • Dobrovolskaia, M.A.1    Vogel, S.N.2
  • 74
    • 37049018219 scopus 로고    scopus 로고
    • A genome-wide analysis of LPS tolerance in macrophages
    • Mages, J., H. Dietrich, and R. Lang. 2007. A genome-wide analysis of LPS tolerance in macrophages. Immunobiology 212: 723-737
    • (2007) Immunobiology , vol.212 , pp. 723-737
    • Mages, J.1    Dietrich, H.2    Lang, R.3
  • 75
    • 33846207958 scopus 로고    scopus 로고
    • MyD88-dependent and MyD88-independent pathways in synergy, priming, and tolerance between TLR agonists
    • Bagchi, A., E. A. Herrup, H. S. Warren, J. Trigilio, H. S. Shin, C. Valentine, and J. Hellman. 2007. MyD88-dependent and MyD88-independent pathways in synergy, priming, and tolerance between TLR agonists. J. Immunol. 178: 1164-1171
    • (2007) J. Immunol , vol.178 , pp. 1164-1171
    • Bagchi, A.1    Herrup, E.A.2    Warren, H.S.3    Trigilio, J.4    Shin, H.S.5    Valentine, C.6    Hellman, J.7
  • 76
    • 0037218547 scopus 로고    scopus 로고
    • Induction of in vitro reprogramming by Toll-like receptor (TLR)2 and TLR4 agonists in murine macrophages: Effects of TLR
    • Homotolerance versus heterotolerance on NF-kB signaling pathway components
    • Dobrovolskaia, M. A., A. E. Medvedev, K. E. Thomas, N. Cuesta, V. Toshchakov, T. Ren, M. J. Cody, S. M. Michalek, N. R. Rice, and S. N. Vogel. 2003. Induction of in vitro reprogramming by Toll-like receptor (TLR)2 and TLR4 agonists in murine macrophages: Effects of TLR homotolerance versus heterotolerance on NF-kB signaling pathway components. J. Immunol. 170: 508-519
    • (2003) J. Immunol , vol.170 , pp. 508-519
    • Dobrovolskaia, M.A.1    Medvedev, A.E.2    Thomas, K.E.3    Cuesta, N.4    Toshchakov, V.5    Ren, T.6    Cody, M.J.7    Michalek, S.M.8    Rice, N.R.9    Vogel, S.N.10
  • 77
    • 0034671772 scopus 로고    scopus 로고
    • Synergy and cross-tolerance between Toll-like receptor (TLR)2-and TLR4-mediated signaling pathways
    • Sato, S., F. Nomura, T. Kawai, O. Takeuchi, P. F. Muhlradt, K. Takeda, and S. Akira. 2000. Synergy and cross-tolerance between Toll-like receptor (TLR)2-and TLR4-mediated signaling pathways. J. Immunol. 165: 7096-7101
    • (2000) J. Immunol , vol.165 , pp. 7096-7101
    • Sato, S.1    Nomura, F.2    Kawai, T.3    Takeuchi, O.4    Muhlradt, P.F.5    Takeda, K.6    Akira, S.7
  • 78
    • 0031471001 scopus 로고    scopus 로고
    • Induction of endotoxin tolerance depletes nuclear factor-kB and suppresses its activation in rat alveolar macrophages
    • Blackwell, T. S., T. R. Blackwell, and J. W. Christman. 1997. Induction of endotoxin tolerance depletes nuclear factor-kB and suppresses its activation in rat alveolar macrophages. J. Leukoc. Biol. 62: 885-891
    • (1997) J. Leukoc. Biol , vol.62 , pp. 885-891
    • Blackwell, T.S.1    Blackwell, T.R.2    Christman, J.W.3
  • 79
    • 0031570463 scopus 로고    scopus 로고
    • Impaired activation of nuclear factor-kB in endotoxin-tolerant rats is associated with downregulation of chemokine gene expression and inhibition of neutrophilic lung inflammation
    • Blackwell, T. S., T. R. Blackwell, and J.W. Christman. 1997. Impaired activation of nuclear factor-kB in endotoxin-tolerant rats is associated with downregulation of chemokine gene expression and inhibition of neutrophilic lung inflammation. J. Immunol. 158: 5934-5940
    • (1997) J. Immunol , vol.158 , pp. 5934-5940
    • Blackwell, T.S.1    Blackwell, T.R.2    Christman, J.W.3
  • 80
    • 2942534195 scopus 로고    scopus 로고
    • IL-16 is constitutively present in peripheral blood monocytes and spontaneously released during apoptosis
    • Elssner, A., A. I. Doseff, M. Duncan, M. Kotur, and M. D. Wewers. 2004. IL-16 is constitutively present in peripheral blood monocytes and spontaneously released during apoptosis. J. Immunol. 172: 7721-7725
    • (2004) J. Immunol , vol.172 , pp. 7721-7725
    • Elssner, A.1    Doseff, A.I.2    Duncan, M.3    Kotur, M.4    Wewers, M.D.5
  • 86
    • 40949133887 scopus 로고    scopus 로고
    • CpG oligodeoxynucleotides as immunotherapy in cancer
    • Jahrsdörfer, B., and G. J. Weiner. 2008. CpG oligodeoxynucleotides as immunotherapy in cancer. Update Cancer Ther. 3: 27-32
    • (2008) Update Cancer Ther , vol.3 , pp. 27-32
    • Jahrsdörfer, B.1    Weiner, G.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.