Recent progress in light-triggered nanotheranostics for cancer treatment

Theranostics

Volumn 6, Issue 7, 2016, Pages 948-968

  Zhang, Pengcheng ^a   Hu, Chunhua ^a,b   Ran, Wei ^a,c   Meng, Jia ^a,c   Yin, Qi ^a   Li, Yaping ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^c UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

Imaging; Nanoparticle; Photodynamic; Photothermal; Theranostics

Indexed keywords

5,10,15,20 TETRO (4 PYRIDYL)PORPHYRIN; BACTERIOCHLORIN; CARBON NANOTUBE; CHLORIN E6; COPPER NANOPARTICLE; CYANINE DYE; CYPATE; FERRIC FERROCYANIDE; GALLIC ACID; GOLD NANOPARTICLE; GRAPHENE; HEMATOPORPHYRIN; INDOCYANINE GREEN; NANOPARTICLE; PHOTOSENSITIZING AGENT; PHTHALOCYANINE ZINC; POLYANILINE; POLYMER; POLYPYRROLE; PORPHYRIN; PROTOPORPHYRIN; PURPURIN; PURPURIN18; PYROPHEOPHORBIDE; QUANTUM DOT; SINGLE WALLED NANOTUBE; SINOPORPHYRIN; UNCLASSIFIED DRUG; UPCONVERSION NANOPARTICLE; [POLY[SODIUM 3 [(3 METHYL 3,4 DIHYDRO 2H THIENO[3,4 B][1,4]DIOXEPI N 3 YL)METHOXY]PROPANE 1 SULFONATE]];

CANCER CELL; CANCER RESEARCH; CANCER THERAPY; COMPUTER ASSISTED TOMOGRAPHY; FLUORESCENCE IMAGING; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMAN; LIGHT TRIGGERED NANOTHERANOSTICS; NEOPLASM; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PERSONALIZED MEDICINE; PHOTOACOUSTIC TOMOGRAPHY; PHOTOTHERAPY; POSITRON EMISSION TOMOGRAPHY; RAMAN SPECTROMETRY; REVIEW; THERANOSTIC NANOMEDICINE; TUMOR ABLATION; ANIMAL; DIAGNOSTIC IMAGING; DISEASE MODEL; LIGHT; NEOPLASMS; PROCEDURES; TRENDS;

ANIMALS; DISEASE MODELS, ANIMAL; LIGHT; NANOPARTICLES; NEOPLASMS; PHOTOTHERAPY; THERANOSTIC NANOMEDICINE;

EID: 84979587937     PISSN: None     EISSN: 18387640     Source Type: Journal    
DOI: 10.7150/thno.15217     Document Type: Review

References (203)

1. Torre LA, Bray F, Siegel RL, et al. Global cancer statistics, 2012. CA Cancer J Clin. 2015; 65: 87-108.
2. Bedard PL, Hansen AR, Ratain MJ, et al. Tumour heterogeneity in the clinic. Nature. 2013; 501: 355-64.
3. Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011; 144: 646-74.
4. Mura S, Couvreur P. Nanotheranostics for personalized medicine. Adv Drug Deliv Rev. 2012; 64: 1394-416.
5. Cheng Z, Al Zaki A, Hui JZ, et al. Multifunctional nanoparticles: cost versus benefit of adding targeting and imaging capabilities. Science. 2012; 338: 903-10.
6. Koo H, Huh MS, Sun IC, et al. In vivo targeted delivery of nanoparticles for theranosis. Acc Chem Res. 2011; 44: 1018-28.
7. Chen Q, Ke H, Dai Z, et al. Nanoscale theranostics for physical stimulus-responsive cancer therapies. Biomaterials. 2015; 73: 214-30.
8. Zhang P, Cheetham AG, Lock LL, et al. Activatable nanoprobes for biomolecular detection. Curr Opin Biotechnol. 2015; 34: 171-9.
9. Tong HJ, Lou KY, Wang W. Near-infrared fluorescent probes for imaging of amyloid plaques in Alzheimer's disease. Acta Pharm Sin B. 2015; 5: 25-33.
10. Agostinis P, Berg K, Cengel KA, et al. Photodynamic therapy of cancer: an update. CA Cancer J Clin. 2011; 61: 250-81.
11. Josefsen LB, Boyle RW. Unique diagnostic and therapeutic roles of porphyrins and phthalocyanines in photodynamic therapy, imaging and theranostics. Theranostics. 2012; 2: 916-66.
12. Awuah SG, You Y. Boron dipyrromethene (BODIPY)-based photosensitizers for photodynamic therapy. Rsc Advances. 2012; 2: 11169-83.
13. Lucky SS, Soo KC, Zhang Y. Nanoparticles in photodynamic therapy. Chem Rev. 2015; 115: 1990-2042.
14. Dykman L, Khlebtsov N. Gold nanoparticles in biomedical applications: recent advances and perspectives. Chem Soc Rev. 2012; 41: 2256-82.
15. Zhang Z, Wang J, Chen C. Near-infrared light-mediated nanoplatforms for cancer thermo-chemotherapy and optical imaging. Adv Mater. 2013; 25: 3869-80.
16. Ng KK, Zheng G. Molecular interactions in organic nanoparticles for phototheranostic applications. Chem Rev. 2015; 115: 11012-42.
17. Welsher K, Liu Z, Daranciang D, et al. Selective probing and imaging of cells with single walled carbon nanotubes as near-infrared fluorescent molecules. Nano Lett. 2008; 8: 586-90.
18. Hildebrandt B, Wust P, Ahlers O, et al. The cellular and molecular basis of hyperthermia. Crit Rev Oncol Hematol. 2002; 43: 33-56.
19. Hatz S, Lambert JD, Ogilby PR. Measuring the lifetime of singlet oxygen in a single cell: addressing the issue of cell viability. Photochem Photobiol Sci. 2007; 6: 1106-16.
20. Davies MJ. Singlet oxygen-mediated damage to proteins and its consequences. Biochem Biophys Res Commun. 2003; 305: 761-70.
21. Chen Z, Tabakman SM, Goodwin AP, et al. Protein microarrays with carbon nanotubes as multicolor Raman labels. Nat Biotechnol. 2008; 26: 1285-92.
22. Farhadi A, Roxin A, Wilson BC, et al. Nano-enabled SERS reporting photosensitizers. Theranostics. 2015; 5: 469-76.
23. Jain PK, Huang XH, El-Sayed IH, et al. Noble metals on the nanoscale: optical and photothermal properties and some applications in imaging, sensing, biology, and medicine. Acc Chem Res. 2008; 41: 1578-86.
24. Luther JM, Jain PK, Ewers T, et al. Localized surface plasmon resonances arising from free carriers in doped quantum dots. Nat Mater. 2011; 10: 361-6.
25. Xie Y, Carbone L, Nobile C, et al. Metallic-like stoichiometric copper sulfide nanocrystals: phase- and shape-selective synthesis, near-infrared surface plasmon resonance properties, and their modeling. ACS Nano. 2013; 7: 7352-69.
26. Melancon MP, Zhou M, Li C. Cancer theranostics with near-infrared light-activatable multimodal nanoparticles. Acc Chem Res. 2011; 44: 947-56.
27. Song J, Huang P, Duan H, et al. Plasmonic vesicles of amphiphilic nanocrystals: optically active multifunctional platform for cancer diagnosis and therapy. Acc Chem Res. 2015; 48: 2506-15.
28. Cai RX, Kubota Y, Shuin T, et al. Induction of cytotoxicity by photoexcited Tio2 particles. Cancer Res. 1992; 52: 2346-48.
29. Hackenberg S, Scherzed A, Kessler M, et al. Zinc oxide nanoparticles induce photocatalytic cell death in human head and neck squamous cell carcinoma cell lines in vitro. Int J Oncol. 2010; 37: 1583-90.
30. Mura S, Nicolas J, Couvreur P. Stimuli-responsive nanocarriers for drug delivery. Nat Mater. 2013; 12: 991-1003.
31. Priya James H, John R, Alex A, et al. Smart polymers for the controlled delivery of drugs - a concise overview. Acta Pharm Sin B. 2014; 4: 120-7.
32. Carter KA, Shao S, Hoopes MI, et al. Porphyrin-phospholipid liposomes permeabilized by near-infrared light. Nat Commun. 2014; 5: 3546.
33. Luo D, Carter KA, Razi A, et al. Doxorubicin encapsulated in stealth liposomes conferred with light-triggered drug release. Biomaterials. 2016; 75: 193-202.
34. Dai Y, Xiao H, Liu J, et al. In vivo multimodality imaging and cancer therapy by near-infrared light-triggered trans-platinum pro-drug-conjugated upconverison nanoparticles. J Am Chem Soc. 2013; 135: 18920-9.
35. Dougherty TJ, Grindey GB, Fiel R, et al. Photoradiation therapy.2. cure of animal tumors with hematoporphyrin and light. J Natl Cancer Inst. 1975; 55: 115-21.
36. Song XJ, Chen Q, Liu Z. Recent advances in the development of organic photothermal nano-agents. Nano Research. 2015; 8: 340-54.
37. Fuhrmann G, Serio A, Mazo M, et al. Active loading into extracellular vesicles significantly improves the cellular uptake and photodynamic effect of porphyrins. J Control Release. 2015; 205: 35-44.
38. Rai P, Mallidi S, Zheng X, et al. Development and applications of photo-triggered theranostic agents. Adv Drug Deliv Rev. 2010; 62: 1094-124.
39. Yang J, Choi J, Bang D, et al. Convertible organic nanoparticles for near-infrared photothermal ablation of cancer cells. Angew Chem Int Ed Engl. 2011; 50: 441-4.
40. Ethirajan M, Chen Y, Joshi P, et al. The role of porphyrin chemistry in tumor imaging and photodynamic therapy. Chem Soc Rev. 2011; 40: 340-62.
41. Lovell JF, Jin CS, Huynh E, et al. Porphysome nanovesicles generated by porphyrin bilayers for use as multimodal biophotonic contrast agents. Nat Mater. 2011; 10: 324-32.
42. Muhanna N, Jin CS, Huynh E, et al. Phototheranostic porphyrin nanoparticles enable visualization and targeted treatment of head and neck cancer in clinically relevant models. Theranostics. 2015; 5: 1428-43.
43. Huynh E, Leung BY, Helfield BL, et al. In situ conversion of porphyrin microbubbles to nanoparticles for multimodality imaging. Nat Nanotechnol. 2015; 10: 325-32.
44. Spring BQ, Bryan Sears R, Zheng LZ, et al. A photoactivable multi-inhibitor nanoliposome for tumour control and simultaneous inhibition of treatment escape pathways. Nat Nanotechnol. 2016; doi:10.1038/nnano.2015.311.
45. Zhang D, Qi GB, Zhao YX, et al. In situ formation of nanofibers from Purpurin18-peptide conjugates and the assembly induced retention effect in tumor sites. Adv Mater. 2015; 27: 6125-30.
46. Park SY, Baik HJ, Oh YT, et al. A smart polysaccharide/drug conjugate for photodynamic therapy. Angew Chem Int Ed Engl. 2011; 50: 1644-7.
47. Lee SJ, Koo H, Lee DE, et al. Tumor-homing photosensitizer-conjugated glycol chitosan nanoparticles for synchronous photodynamic imaging and therapy based on cellular on/offsystem. Biomaterials. 2011; 32: 4021-9.
48. Yoon HY, Koo H, Choi KY, et al. Tumor-targeting hyaluronic acid nanoparticles for photodynamic imaging and therapy. Biomaterials. 2012; 33: 3980-9.
49. Cheng Y, Meyers JD, Broome AM, et al. Deep penetration of a PDT drug into tumors by noncovalent drug-gold nanoparticle conjugates. J Am Chem Soc. 2011; 133: 2583-91.
50. Zhang J, Liang YC, Lin X, et al. Self-monitoring and self-delivery of photosensitizer-doped nanoparticles for highly effective combination cancer therapy in vitro and in vivo. ACS Nano. 2015; 9: 9741-56.
51. Cui L, Lin Q, Jin CS, et al. A PEGylation-free biomimetic porphyrin nanoplatform for personalized cancer theranostics. ACS Nano. 2015; 9: 4484-95.
52. Rensen PC, de Vrueh RL, Kuiper J, et al. Recombinant lipoproteins: lipoprotein-like lipid particles for drug targeting. Adv Drug Deliv Rev. 2001; 47: 251-76.
53. Geim AK, Novoselov KS. The rise of graphene. Nat Mater. 2007; 6: 183-91.
54. Yan X, Niu G, Lin J, et al. Enhanced fluorescence imaging guided photodynamic therapy of sinoporphyrin sodium loaded graphene oxide. Biomaterials. 2015; 42: 94-102.
55. Choi Y, Kim S, Choi MH, et al. Highly biocompatible carbon nanodots for simultaneous bioimaging and targeted photodynamic therapy in vitro and in vivo. Adv Funct Mater. 2014; 24: 5781-89.
56. Huang P, Lin J, Wang S, et al. Photosensitizer-conjugated silica-coated gold nanoclusters for fluorescence imaging-guided photodynamic therapy. Biomaterials. 2013; 34: 4643-54.
57. Xie J, Zheng Y, Ying JY. Protein-directed synthesis of highly fluorescent gold nanoclusters. J Am Chem Soc. 2009; 131: 888-9.
58. Li Z, Wang C, Cheng L, et al. PEG-functionalized iron oxide nanoclusters loaded with chlorin e6 for targeted, NIR light induced, photodynamic therapy. Biomaterials. 2013; 34: 9160-70.
59. Xuan SH, Lee SF, Lau JT, et al. Photocytotoxicity and magnetic relaxivity responses of dual-porous gamma-Fe2O3@meso-SiO2 microspheres. ACS Appl Mater Interfaces. 2012; 4: 2033-40.
60. Ling D, Park W, Park SJ, et al. Multifunctional tumor pH-sensitive self-assembled nanoparticles for bimodal imaging and treatment of resistant heterogeneous tumors. J Am Chem Soc. 2014; 136: 5647-55.
61. Il Park Y, Lee KT, Suh YD, et al. Upconverting nanoparticles: a versatile platform for wide-field two-photon microscopy and multi-modal in vivo imaging. Chem Soc Rev. 2015; 44: 1302-17.
62. Liu K, Liu X, Zeng Q, et al. Covalently assembled NIR nanoplatform for simultaneous fluorescence imaging and photodynamic therapy of cancer cells. ACS Nano. 2012; 6: 4054-62.
63. Wang C, Tao H, Cheng L, et al. Near-infrared light induced in vivo photodynamic therapy of cancer based on upconversion nanoparticles. Biomaterials. 2011; 32: 6145-54.
64. Idris NM, Gnanasammandhan MK, Zhang J, et al. In vivo photodynamic therapy using upconversion nanoparticles as remote-controlled nanotransducers. Nat Med. 2012; 18: 1580-5.
65. Wang C, Cheng L, Liu YM, et al. Imaging-guided pH-sensitive photodynamic therapy using charge reversible upconversion nanoparticles under near-infrared light. Adv Funct Mater. 2013; 23: 3077-86.
66. Cui S, Yin D, Chen Y, et al. In vivo targeted deep-tissue photodynamic therapy based on near-infrared light triggered upconversion nanoconstruct. ACS Nano. 2013; 7: 676-88.
67. Ai X, Ho CJ, Aw J, et al. In vivo covalent cross-linking of photon-converted rare-earth nanostructures for tumour localization and theranostics. Nat Commun. 2016; 7: 10432.
68. Park YI, Kim HM, Kim JH, et al. Theranostic probe based on lanthanide-doped nanoparticles for simultaneous in vivo dual-modal imaging and photodynamic therapy. Adv Mater. 2012; 24: 5755-61.
69. Fan W, Shen B, Bu W, et al. A smart upconversion-based mesoporous silica nanotheranostic system for synergetic chemo-/radio-/photodynamic therapy and simultaneous MR/UCL imaging. Biomaterials. 2014; 35: 8992-9002.
70. Tian G, Ren W, Yan L, et al. Red-emitting upconverting nanoparticles for photodynamic therapy in cancer cells under near-infrared excitation. Small. 2013; 9: 1929-38.
71. Huang P, Lin J, Wang X, et al. Light-triggered theranostics based on photosensitizer-conjugated carbon dots for simultaneous enhanced-fluorescence imaging and photodynamic therapy. Adv Mater. 2012; 24: 5104-10.
72. Roberts WG, Smith KM, Mccullough JL, et al. Skin photosensitivity and photodestruction of several potential photodynamic sensitizers. Photochem Photobiol. 1989; 49: 431-38.
73. Harris AL. Hypoxia--a key regulatory factor in tumour growth. Nat Rev Cancer. 2002; 2: 38-47.
74. Luo SL, Zhang EL, Su YP, et al. A review of NIR dyes in cancer targeting and imaging. Biomaterials. 2011; 32: 7127-38.
75. Yu J, Javier D, Yaseen MA, et al. Self-assembly synthesis, tumor cell targeting, and photothermal capabilities of antibody-coated indocyanine green nanocapsules. J Am Chem Soc. 2010; 132: 1929-38.
76. Yue C, Liu P, Zheng M, et al. IR-780 dye loaded tumor targeting theranostic nanoparticles for NIR imaging and photothermal therapy. Biomaterials. 2013; 34: 6853-61.
77. Huang P, Gao Y, Lin J, et al. Tumor-specific formation of enzyme-instructed supramolecular self-assemblies as cancer theranostics. ACS Nano. 2015; 9: 9517-27.
78. Sheng Z, Hu D, Zheng M, et al. Smart human serum albumin-indocyanine green nanoparticles generated by programmed assembly for dual-modal imaging-guided cancer synergistic phototherapy. ACS Nano. 2014; 8: 12310-22.
79. Wu L, Fang S, Shi S, et al. Hybrid polypeptide micelles loading indocyanine green for tumor imaging and photothermal effect study. Biomacromolecules. 2013; 14: 3027-33.
80. Chen Q, Liang C, Wang X, et al. An albumin-based theranostic nano-agent for dual-modal imaging guided photothermal therapy to inhibit lymphatic metastasis of cancer post surgery. Biomaterials. 2014; 35: 9355-62.
81. Huang P, Rong P, Jin A, et al. Dye-loaded ferritin nanocages for multimodal imaging and photothermal therapy. Adv Mater. 2014; 26: 6401-8.
82. Chen Q, Liang C, Wang C, et al. An imagable and photothermal "Abraxane-like" nanodrug for combination cancer therapy to treat subcutaneous and metastatic breast tumors. Adv Mater. 2015; 27: 903-10.
83. Rong P, Huang P, Liu Z, et al. Protein-based photothermal theranostics for imaging-guided cancer therapy. Nanoscale. 2015; 7: 16330-6.
84. Wang Y, Yang T, Ke H, et al. Smart albumin-biomineralized nanocomposites for multimodal imaging and photothermal tumor ablation. Adv Mater. 2015; 27: 3874-82.
85. Zheng M, Yue C, Ma Y, et al. Single-step assembly of DOX/ICG loaded lipid--polymer nanoparticles for highly effective chemo-photothermal combination therapy. ACS Nano. 2013; 7: 2056-67.
86. Wan Z, Mao H, Guo M, et al. Highly efficient hierarchical micelles integrating photothermal therapy and singlet oxygen-synergized chemotherapy for cancer eradication. Theranostics. 2014; 4: 399-411.
87. He XY, Bao XY, Cao HQ, et al. Tumor-penetrating nanotherapeutics loading a near-infrared probe inhibit growth and metastasis of breast cancer. Adv Funct Mater. 2015; 25: 2831-39.
88. Peng CL, Shih YH, Lee PC, et al. Multimodal image-guided photothermal therapy mediated by 188Re-labeled micelles containing a cyanine-type photosensitizer. ACS Nano. 2011; 5: 5594-607.
89. Zhu A, Miao K, Deng Y, et al. Dually pH/reduction-responsive vesicles for ultrahigh-contrast fluorescence imaging and thermo-chemotherapy-synergized tumor ablation. ACS Nano. 2015; 9: 7874-85.
90. Chen Q, Wang C, Cheng L, et al. Protein modified upconversion nanoparticles for imaging-guided combined photothermal and photodynamic therapy. Biomaterials. 2014; 35: 2915-23.
91. Ma Y, Tong S, Bao G, et al. Indocyanine green loaded SPIO nanoparticles with phospholipid-PEG coating for dual-modal imaging and photothermal therapy. Biomaterials. 2013; 34: 7706-14.
92. He XM, Carter DC. Atomic-structure and chemistry of human serum-albumin. Nature. 1992; 358: 209-15.
93. Elzoghby AO, Samy WM, Elgindy NA. Albumin-based nanoparticles as potential controlled release drug delivery systems. J Control Release. 2012; 157: 168-82.
94. Munro HN, Linder MC. Ferritin: structure, biosynthesis, and role in iron metabolism. Physiol Rev. 1978; 58: 317-96.
95. Yu HJ, Cui ZR, Yu PC, et al. pH- and NIR light-responsive micelles with hyperthermia-triggered tumor penetration and cytoplasm drug release to reverse doxorubicin resistance in breast cancer. Adv Funct Mater. 2015; 25: 2489-500.
96. Ding D, Li K, Liu B, et al. Bioprobes based on AIE fluorogens. Acc Chem Res. 2013; 46: 2441-53.
97. Yuan Y, Feng G, Qin W, et al. Targeted and image-guided photodynamic cancer therapy based on organic nanoparticles with aggregation-induced emission characteristics. Chem Commun (Camb). 2014; 50: 8757-60.
98. Hong Y, Lam JW, Tang BZ. Aggregation-induced emission: phenomenon, mechanism and applications. Chem Commun (Camb). 2009: 4332-53.
99. Yuan Y, Zhang CJ, Gao M, et al. Specific light-up bioprobe with aggregation-induced emission and activatable photoactivity for the targeted and image-guided photodynamic ablation of cancer cells. Angew Chem Int Ed Engl. 2015; 54: 1780-6.
100. Kim J, Lee E, Hong Y, et al. Self-doped conjugated polymeric nanoassembly by simplified process for optical cancer theragnosis. Adv Funct Mater. 2015; 25: 2260-69.
101. Wang C, Xu H, Liang C, et al. Iron oxide @ polypyrrole nanoparticles as a multifunctional drug carrier for remotely controlled cancer therapy with synergistic antitumor effect. ACS Nano. 2013; 7: 6782-95.
102. Song XJ, Gong H, Yin SN, et al. Ultra- small iron oxide doped polypyrrole nanoparticles for in vivo multimodal imaging guided photothermal therapy. Adv Funct Mater. 2014; 24: 1194-201.
103. Liang XL, Li YY, Li XD, et al. PEGylated polypyrrole nanoparticles conjugating gadolinium chelates for dual-modal MRI/photoacoustic imaging guided photothermal therapy of cancer. Adv Funct Mater. 2015; 25: 1451-62.
104. Liu F, He X, Chen H, et al. Gram-scale synthesis of coordination polymer nanodots with renal clearance properties for cancer theranostic applications. Nat Commun. 2015; 6: 8003.
105. Cai XJ, Jia XQ, Gao W, et al. A versatile nanotheranostic agent for efficient dual-mode imaging guided synergistic chemo-thermal tumor therapy. Adv Funct Mater. 2015; 25: 2520-29.
106. Huang HC, Barua S, Sharma G, et al. Inorganic nanoparticles for cancer imaging and therapy. J Control Release. 2011; 155: 344-57.
107. Michalet X, Pinaud FF, Bentolila LA, et al. Quantum dots for live cells, in vivo imaging, and diagnostics. Science. 2005; 307: 538-44.
108. Zhao YX, Pan HC, Lou YB, et al. Plasmonic Cu2-xS nanocrystals: optical and structural properties of copper-deficient copper(I) sulfides. J Am Chem Soc. 2009; 131: 4253-61.
109. Goel S, Chen F, Cai WB. Synthesis and biomedical applications of copper sulfide nanoparticles: from sensors to theranostics. Small. 2014; 10: 631-45.
110. Park SH, Roy A, Beaupre S, et al. Bulk heterojunction solar cells with internal quantum efficiency approaching 100%. Nat Photonics. 2009; 3: 297-U5.
111. Kataura H, Kumazawa Y, Maniwa Y, et al. Optical properties of single-wall carbon nanotubes. Synth Met. 1999; 103: 2555-58.
112. Bonaccorso F, Sun Z, Hasan T, et al. Graphene photonics and optoelectronics. Nat Photonics. 2010; 4: 611-22.
113. Jin Y, Jia C, Huang SW, et al. Multifunctional nanoparticles as coupled contrast agents. Nat Commun. 2010; 1: 41.
114. Li W, Chen X. Gold nanoparticles for photoacoustic imaging. Nanomedicine (Lond). 2015; 10: 299-320.
115. Idris NM, Lucky SS, Li ZQ, et al. Photoactivation of core-shell titania coated upconversion nanoparticles and their effect on cell death. J Mat Chem B. 2014; 2: 7017-26.
116. Zhang Z, Wang L, Wang J, et al. Mesoporous silica-coated gold nanorods as a light-mediated multifunctional theranostic platform for cancer treatment. Adv Mater. 2012; 24: 1418-23.
117. Chen J, Glaus C, Laforest R, et al. Gold nanocages as photothermal transducers for cancer treatment. Small. 2010; 6: 811-7.
118. Kuo WS, Chang CN, Chang YT, et al. Gold nanorods in photodynamic therapy, as hyperthermia agents, and in near-infrared optical imaging. Angew Chem Int Ed Engl. 2010; 49: 2711-5.
119. Xia Y, Li W, Cobley CM, et al. Gold nanocages: from synthesis to theranostic applications. Acc Chem Res. 2011; 44: 914-24.
120. Zhang Z, Wang J, Chen C. Gold nanorods based platforms for light-mediated theranostics. Theranostics. 2013; 3: 223-38.
121. Westcott SL, Oldenburg SJ, Lee TR, et al. Construction of simple gold nanoparticle aggregates with controlled plasmon-plasmon interactions. Chem Phys Lett. 1999; 300: 651-55.
122. Lu W, Melancon MP, Xiong C, et al. Effects of photoacoustic imaging and photothermal ablation therapy mediated by targeted hollow gold nanospheres in an orthotopic mouse xenograft model of glioma. Cancer Res. 2011; 71: 6116-21.
123. Ye SJ, Marston G, McLaughlan JR, et al. Engineering gold nanotubes with controlled length and near-infrared absorption for theranostic applications. Adv Funct Mater. 2015; 25: 2117-27.
124. Hembury M, Chiappini C, Bertazzo S, et al. Gold-silica quantum rattles for multimodal imaging and therapy. Proc Natl Acad Sci U S A. 2015; 112: 1959-64.
125. Huang P, Rong PF, Lin J, et al. Triphase interface synthesis of plasmonic gold bellflowers as near-infrared light mediated acoustic and thermal theranostics. J Am Chem Soc. 2014; 136: 8307-13.
126. Wang X, Wang C, Cheng L, et al. Noble metal coated single-walled carbon nanotubes for applications in surface enhanced Raman scattering imaging and photothermal therapy. J Am Chem Soc. 2012; 134: 7414-22.
127. Dong W, Li Y, Niu D, et al. Facile synthesis of monodisperse superparamagnetic Fe3O4 Core@hybrid@Au shell nanocomposite for bimodal imaging and photothermal therapy. Adv Mater. 2011; 23: 5392-7.
128. Ma Y, Liang XL, Tong S, et al. Gold nanoshell nanomicelles for potential magnetic resonance imaging, light-triggered drug release, and photothermal therapy. Adv Funct Mater. 2013; 23: 815-22.
129. Li CM, Chen T, Ocsoy I, et al. Gold- coated Fe3O4 nanoroses with five unique functions for cancer cell targeting, imaging, and therapy. Adv Funct Mater. 2014; 24: 1772-80.
130. Wang DW, Zhu XM, Lee SF, et al. Folate-conjugated Fe3O4@SiO2@gold nanorods@mesoporous SiO2 hybrid nanomaterial: a theranostic agent for magnetic resonance imaging and photothermal therapy. J Mater Chem B. 2013; 1: 2934-42.
131. Huang J, Guo M, Ke H, et al. Rational design and synthesis of gammaFe2O3 @Au magnetic gold nanoflowers for efficient cancer theranostics. Adv Mater. 2015; 27: 5049-56.
132. Sun X, Huang X, Yan X, et al. Chelator-free (64)Cu-integrated gold nanomaterials for positron emission tomography imaging guided photothermal cancer therapy. ACS Nano. 2014; 8: 8438-46.
133. Deng H, Dai F, Ma G, et al. Theranostic gold nanomicelles made from biocompatible comb-like polymers for thermochemotherapy and multifunctional imaging with rapid clearance. Adv Mater. 2015; 27: 3645-53.
134. Song J, Zhou J, Duan H. Self-assembled plasmonic vesicles of SERS-encoded amphiphilic gold nanoparticles for cancer cell targeting and traceable intracellular drug delivery. J Am Chem Soc. 2012; 134: 13458-69.
135. Lin J, Wang S, Huang P, et al. Photosensitizer-loaded gold vesicles with strong plasmonic coupling effect for imaging-guided photothermal/photodynamic therapy. ACS Nano. 2013; 7: 5320-9.
136. Huang P, Lin J, Li W, et al. Biodegradable gold nanovesicles with an ultrastrong plasmonic coupling effect for photoacoustic imaging and photothermal therapy. Angew Chem Int Ed Engl. 2013; 52: 13958-64.
137. Song J, Yang X, Jacobson O, et al. Ultrasmall gold nanorod vesicles with enhanced tumor accumulation and fast excretion from the body for cancer therapy. Adv Mater. 2015; 27: 4910-7.
138. Song J, Yang X, Jacobson O, et al. Sequential drug release and enhanced photothermal and photoacoustic effect of hybrid reduced graphene oxide-loaded ultrasmall gold nanorod vesicles for cancer therapy. ACS Nano. 2015; 9: 9199-209.
139. Song J, Cheng L, Liu A, et al. Plasmonic vesicles of amphiphilic gold nanocrystals: self-assembly and external-stimuli-triggered destruction. J Am Chem Soc. 2011; 133: 10760-3.
140. He J, Liu YJ, Babu T, et al. Self-assembly of inorganic nanoparticle vesicles and tubules driven by tethered linear block copolymers. J Am Chem Soc. 2012; 134: 11342-45.
141. Haram SK, Mahadeshwar AR, Dixit SG. Synthesis and characterization of copper sulfide nanoparticles in Triton-X 100 water-in-oil microemulsions. J Phys Chem. 1996; 100: 5868-73.
142. Li Y, Lu W, Huang Q, et al. Copper sulfide nanoparticles for photothermal ablation of tumor cells. Nanomedicine (Lond). 2010; 5: 1161-71.
143. Ku G, Zhou M, Song S, et al. Copper sulfide nanoparticles as a new class of photoacoustic contrast agent for deep tissue imaging at 1064 nm. ACS Nano. 2012; 6: 7489-96.
144. Zhou M, Li J, Liang S, et al. CuS nanodots with ultrahigh efficient renal clearance for positron emission tomography imaging and image-guided photothermal therapy. ACS Nano. 2015; 9: 7085-96.
145. Zhou M, Zhang R, Huang M, et al. A chelator-free multifunctional [64Cu]CuS nanoparticle platform for simultaneous micro-PET/CT imaging and photothermal ablation therapy. J Am Chem Soc. 2010; 132: 15351-8.
146. Liu R, Jing L, Peng D, et al. Manganese (II) chelate functionalized copper sulfide nanoparticles for efficient magnetic resonance/photoacoustic dual-modal imaging guided photothermal therapy. Theranostics. 2015; 5: 1144-53.
147. Xiao Q, Zheng X, Bu W, et al. A core/satellite multifunctional nanotheranostic for in vivo imaging and tumor eradication by radiation/photothermal synergistic therapy. J Am Chem Soc. 2013; 135: 13041-8.
148. Yi X, Yang K, Liang C, et al. Imaging-guided combined photothermal and radiotherapy to treat subcutaneous and metastatic tumors using Iodine-131-doped copper sulfide nanoparticles. Adv Funct Mater. 2015; 25: 4689-99.
149. Zhang L, Gao S, Zhang F, et al. Activatable hyaluronic acid nanoparticle as a theranostic agent for optical/photoacoustic image-guided photothermal therapy. ACS Nano. 2014; 8: 12250-8.
150. Chen F, Hong H, Goel S, et al. In vivo tumor vasculature targeting of CuS@MSN based theranostic nanomedicine. ACS Nano. 2015; 9: 3926-34.
151. Wu ZC, Li WP, Luo CH, et al. Rattle-yype Fe3O4@CuS developed to conduct magnetically guided photoinduced hyperthermia at first and second NIR biological windows. Adv Funct Mater. 2015; 25: 6527-37.
152. Chou SS, Kaehr B, Kim J, et al. Chemically exfoliated MoS2 as near-infrared photothermal agents. Angew Chem Int Ed Engl. 2013; 52: 4160-4.
153. Liu T, Shi S, Liang C, et al. Iron oxide decorated MoS2 nanosheets with double PEGylation for chelator-free radiolabeling and multimodal imaging guided photothermal therapy. ACS Nano. 2015; 9: 950-60.
154. Yin W, Yan L, Yu J, et al. High-throughput synthesis of single-layer MoS2 nanosheets as a near-infrared photothermal-triggered drug delivery for effective cancer therapy. ACS Nano. 2014; 8: 6922-33.
155. Wang S, Li X, Chen Y, et al. A facile one-pot synthesis of a two-dimensional MoS2/Bi2S3 composite theranostic nanosystem for multi-modality tumor imaging and therapy. Adv Mater. 2015; 27: 2775-82.
156. Yu J, Yin W, Zheng X, et al. Smart MoS2/Fe3O4 nanotheranostic for magnetically targeted photothermal therapy guided by magnetic resonance/photoacoustic imaging. Theranostics. 2015; 5: 931-45.
157. Cheng L, Liu J, Gu X, et al. PEGylated WS(2) nanosheets as a multifunctional theranostic agent for in vivo dual-modal CT/photoacoustic imaging guided photothermal therapy. Adv Mater. 2014; 26: 1886-93.
158. Cheng L, Yuan C, Shen S, et al. Bottom-up synthesis of metal-ion-doped WS2 nanoflakes for cancer theranostics. ACS Nano. 2015; 9: 11090-101.
159. Yang G, Gong H, Liu T, et al. Two-dimensional magnetic WS2@Fe3O4 nanocomposite with mesoporous silica coating for drug delivery and imaging-guided therapy of cancer. Biomaterials. 2015; 60: 62-71.
160. Qian X, Shen S, Liu T, et al. Two-dimensional TiS(2) nanosheets for in vivo photoacoustic imaging and photothermal cancer therapy. Nanoscale. 2015; 7: 6380-7.
161. Yang K, Yang G, Chen L, et al. FeS nanoplates as a multifunctional nano-theranostic for magnetic resonance imaging guided photothermal therapy. Biomaterials. 2015; 38: 1-9.
162. Liu J, Zheng X, Yan L, et al. Bismuth sulfide nanorods as a precision nanomedicine for in vivo multimodal imaging-guided photothermal therapy of tumor. ACS Nano. 2015; 9: 696-707.
163. Song G, Liang C, Gong H, et al. Core-shell MnSe@Bi2Se3 fabricated via a cation exchange method as novel nanotheranostics for multimodal imaging and synergistic thermoradiotherapy. Adv Mater. 2015; 27: 6110-7.
164. Song XR, Wang X, Yu SX, et al. Co9Se8 nanoplates as a new theranostic platform for photoacoustic/magnetic resonance dual-modal-imaging-guided chemo-photothermal combination therapy. Adv Mater. 2015; 27: 3285-91.
165. Kam NWS, O'Connell M, Wisdom JA, et al. Carbon nanotubes as multifunctional biological transporters and near-infrared agents for selective cancer cell destruction. Proc Natl Acad Sci U S A. 2005; 102: 11600-05.
166. Liu Z, Cai W, He L, et al. In vivo biodistribution and highly efficient tumour targeting of carbon nanotubes in mice. Nat Nanotechnol. 2007; 2: 47-52.
167. Singh R, Pantarotto D, Lacerda L, et al. Tissue biodistribution and blood clearance rates of intravenously administered carbon nanotube radiotracers. Proc Natl Acad Sci U S A. 2006; 103: 3357-62.
168. Liu Z, Davis C, Cai W, et al. Circulation and long-term fate of functionalized, biocompatible single-walled carbon nanotubes in mice probed by Raman spectroscopy. Proc Natl Acad Sci U S A. 2008; 105: 1410-5.
169. Moon HK, Lee SH, Choi HC. In vivo near-infrared mediated tumor destruction by photothermal effect of carbon nanotubes. ACS Nano. 2009; 3: 3707-13.
170. Antaris AL, Robinson JT, Yaghi OK, et al. Ultra-low doses of chirality sorted (6,5) carbon nanotubes for simultaneous tumor imaging and photothermal therapy. ACS Nano. 2013; 7: 3644-52.
171. Liu JJ, Wang C, Wang XJ, et al. Mesoporous silica coated single-walled carbon nanotubes as a multifunctional light-responsive platform for cancer combination therapy. Adv Funct Mater. 2015; 25: 384-92.
172. Cao MS, Yang J, Song WL, et al. Ferroferric oxide/multiwalled carbon nanotube vs polyaniline/ferroferric oxide/multiwalled carbon nanotube multiheterostructures for highly effective microwave absorption. ACS Appl Mater Interfaces. 2012; 4: 6949-56.
173. Liang C, Diao S, Wang C, et al. Tumor metastasis inhibition by imaging-guided photothermal therapy with single-walled carbon nanotubes. Adv Mater. 2014; 26: 5646-52.
174. Yang K, Feng L, Shi X, et al. Nano-graphene in biomedicine: theranostic applications. Chem Soc Rev. 2013; 42: 530-47.
175. Yoo JM, Kang JH, Hong BH. Graphene-based nanomaterials for versatile imaging studies. Chem Soc Rev. 2015; 44: 4835-52.
176. Yang K, Zhang S, Zhang G, et al. Graphene in mice: ultrahigh in vivo tumor uptake and efficient photothermal therapy. Nano Lett. 2010; 10: 3318-23.
177. Robinson JT, Tabakman SM, Liang YY, et al. Ultrasmall reduced graphene oxide with high near-infrared absorbance for photothermal therapy. J Am Chem Soc. 2011; 133: 6825-31.
178. Hu SH, Chen YW, Hung WT, et al. Quantum-dot-tagged reduced graphene oxide nanocomposites for bright fluorescence bioimaging and photothermal therapy monitored in situ. Adv Mater. 2012; 24: 1748-54.
179. Yang K, Hu L, Ma X, et al. Multimodal imaging guided photothermal therapy using functionalized graphene nanosheets anchored with magnetic nanoparticles. Adv Mater. 2012; 24: 1868-72.
180. Shi X, Gong H, Li Y, et al. Graphene-based magnetic plasmonic nanocomposite for dual bioimaging and photothermal therapy. Biomaterials. 2013; 34: 4786-93.
181. Ge J, Jia Q, Liu W, et al. Red-emissive carbon dots for fluorescent, photoacoustic, and thermal theranostics in living mice. Adv Mater. 2015; 27: 4169-77.
182. Ge J, Lan M, Zhou B, et al. A graphene quantum dot photodynamic therapy agent with high singlet oxygen generation. Nat Commun. 2014; 5: 4596.
183. Moon H, Kumar D, Kim H, et al. Amplified photoacoustic performance and enhanced photothermal stability of reduced graphene oxide coated gold nanorods for sensitive photo acoustic imaging. ACS Nano. 2015; 9: 2711-19.
184. Ding XG, Liow CH, Zhang MX, et al. Surface plasmon resonance enhanced light absorption and photothermal therapy in the second near-infrared window. J Am Chem Soc. 2014; 136: 15684-93.
185. Zhu XL, Shi L, Schmidt MS, et al. Enhanced light-matter interactions in graphene-covered gold nanovoid arrays. Nano Lett. 2013; 13: 4690-96.
186. Gong H, Dong ZL, Liu YM, et al. Engineering of multifunctional nano-micelles for combined photothermal and photodynamic therapy under the guidance of multimodal imaging. Adv Funct Mater. 2014; 24: 6492-502.
187. Guo M, Mao H, Li Y, et al. Dual imaging-guided photothermal/photodynamic therapy using micelles. Biomaterials. 2014; 35: 4656-66.
188. Song X, Liang C, Gong H, et al. Photosensitizer-conjugated albumin-polypyrrole nanoparticles for imaging-guided in vivo photodynamic/photothermal therapy. Small. 2015; 11: 3932-41.
189. Chen R, Wang X, Yao X, et al. Near-IR-triggered photothermal/photodynamic dual-modality therapy system via chitosan hybrid nanospheres. Biomaterials. 2013; 34: 8314-22.
190. Jang B, Park JY, Tung CH, et al. Gold nanorod-photosensitizer complex for near-infrared fluorescence imaging and photodynamic/photothermal therapy in vivo. ACS Nano. 2011; 5: 1086-94.
191. Wang Y, Wang H, Liu D, et al. Graphene oxide covalently grafted upconversion nanoparticles for combined NIR mediated imaging and photothermal/photodynamic cancer therapy. Biomaterials. 2013; 34: 7715-24.
192. Lv R, Yang P, He F, et al. A yolk-like multifunctional platform for multimodal imaging and synergistic therapy triggered by a single near-infrared light. ACS Nano. 2015; 9: 1630-47.
193. Henderson TA, Morries LD. Near-infrared photonic energy penetration: can infrared phototherapy effectively reach the human brain? Neuropsychiatr Dis Treat. 2015; 11: 2191-208.
194. Cheng L, Wang C, Feng L, et al. Functional nanomaterials for phototherapies of cancer. Chem Rev. 2014; 114: 10869-939.
195. Zhen Z, Tang W, Chuang YJ, et al. Tumor vasculature targeted photodynamic therapy for enhanced delivery of nanoparticles. ACS Nano. 2014; 8: 6004-13.
196. Hong G, Wu JZ, Robinson JT, et al. Three-dimensional imaging of single nanotube molecule endocytosis on plasmonic substrates. Nat Commun. 2012; 3: 700.
197. Wang C, Xu L, Liang C, et al. Immunological responses triggered by photothermal therapy with carbon nanotubes in combination with anti-CTLA-4 therapy to inhibit cancer metastasis. Adv Mater. 2014; 26: 8154-62.
198. Song CW. Effect of local hyperthermia on blood flow and microenvironment: a review. Cancer Res. 1984; 44: 4721s-30s.
199. Min Y, Caster JM, Eblan MJ, et al. Clinical translation of nanomedicine. Chem Rev. 2015; 115: 11147-90.
200. Kolosnjaj-Tabi J, Javed Y, Lartigue L, et al. The one year fate of iron oxide coated gold nanoparticles in mice. ACS Nano. 2015; 9: 7925-39.
201. Soenen SJ, Rivera-Gil P, Montenegro JM, et al. Cellular toxicity of inorganic nanoparticles: Common aspects and guidelines for improved nanotoxicity evaluation. Nano Today. 2011; 6: 446-65.
202. Helmchen F, Denk W. Deep tissue two-photon microscopy. Nat Methods. 2005; 2: 932-40.
203. Bagley AF, Hill S, Rogers GS, et al. Plasmonic photothermal heating of intraperitoneal tumors through the use of an implanted near-infrared source. ACS Nano. 2013; 7: 8089-97.