A smart upconversion-based mesoporous silica nanotheranostic system for synergetic chemo-/radio-/photodynamic therapy and simultaneous MR/UCL imaging

Biomaterials

Volumn 35, Issue 32, 2014, Pages 8992-9002

  Fan, Wenpei ^a   Shen, Bo ^b   Bu, Wenbo ^a   Chen, Feng ^a   He, Qianjun ^a   Zhao, Kuaile ^c   Zhang, Shengjian ^c   Zhou, Liangping ^c   Peng, Weijun ^c   Xiao, Qingfeng ^a   Ni, Dalong ^a   Liu, Jianan ^a   Shi, Jianlin ^a  

^a SHANGHAI INSTITUTE OF CERAMICS   (China)

^b FUDAN UNIVERSITY   (China)

^c FUDAN UNIVERSITY SHANGHAI CANCER CENTER   (China)

Author keywords

Bimodal imaging; Mesoporous silica; Nanotheranostics; Synergetic tri modal therapy; Upconversion nanoparticles

Indexed keywords

DIAGNOSIS; DISEASES; NANOPARTICLES; TUMORS;

CLINICAL DIAGNOSIS; EFFICIENT TREATMENT; MESOPOROUS SILICA; NANOTHERANOSTICS; RADIOSENSITIZERS; SYNERGETIC TRI-MODAL THERAPY; UPCONVERSION NANOPARTICLES; X RAY IRRADIATION;

PHOTODYNAMIC THERAPY;

DOCETAXEL; GADOLINIUM; HEMATOPORPHYRIN; LUMINESCENT AGENT; NANOPARTICLE; NUCLEAR MAGNETIC RESONANCE IMAGING AGENT; UNCLASSIFIED DRUG; UPCONVERSION MESOPOROUS SILICA NANOPARTICLE; BIOMATERIAL; SILICON DIOXIDE;

ANIMAL EXPERIMENT; ANIMAL IMAGING SYSTEM; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER SIZE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG POTENTIATION; DRUG RELEASE; DRUG SYNTHESIS; EXCITATION; FEMALE; HELA CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LASER; LOW DRUG DOSE; LUMINESCENCE; MOUSE; MULTIMODAL IMAGING; MULTIMODALITY CANCER THERAPY; NEAR INFRARED EXCITATION; NEAR INFRARED LASER; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL; RADIOSENSITIZATION; UPCONVERSION LUMINESCENT IMAGING; X IRRADIATION; ANIMAL; BAGG ALBINO MOUSE; CELL SURVIVAL; CHEMISTRY; CONFOCAL MICROSCOPY; DIAGNOSTIC IMAGING; DRUG EFFECTS; INTRAVENOUS DRUG ADMINISTRATION; NANOTECHNOLOGY; PHOTOCHEMOTHERAPY; PROCEDURES; TOXICITY TESTING; TUMOR CELL LINE;

ADMINISTRATION, INTRAVENOUS; ANIMALS; BIOCOMPATIBLE MATERIALS; CELL LINE, TUMOR; CELL SURVIVAL; DIAGNOSTIC IMAGING; DRUG DELIVERY SYSTEMS; FEMALE; HELA CELLS; HUMANS; LUMINESCENCE; MAGNETIC RESONANCE IMAGING; MICE; MICE, INBRED BALB C; MICROSCOPY, CONFOCAL; NANOPARTICLES; NANOTECHNOLOGY; PHOTOCHEMOTHERAPY; SILICON DIOXIDE; TOXICITY TESTS;

EID: 84905751999     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2014.07.024     Document Type: Article

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