A paper/polymer hybrid microfluidic microplate for rapid quantitative detection of multiple disease biomarkers

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Sanjay, Sharma T ^a   Dou, Maowei ^a   Sun, Jianjun ^a   Li, Xiujun ^a  

^a UNIVERSITY OF TEXAS AT EL PASO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5-BROMO-4-CHLORO-3-INDOXYL PHOSPHATE; BIOLOGICAL MARKER; HEPATITIS B SURFACE ANTIGEN; IMMUNOGLOBULIN G; INDOLE DERIVATIVE; NITROBLUE TETRAZOLIUM; POLY(METHYL METHACRYLATE); POLYMER;

BLOOD; CHEMISTRY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; METABOLISM; MICROFLUIDICS; PAPER; PROCEDURES; TIME FACTOR;

BIOMARKERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HEPATITIS B SURFACE ANTIGENS; HUMANS; IMMUNOGLOBULIN G; INDOLES; MICROFLUIDICS; NITROBLUE TETRAZOLIUM; PAPER; POLYMERS; POLYMETHYL METHACRYLATE; TIME FACTORS;

EID: 84979555867     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep30474     Document Type: Article

References (54)

1. Lozano, R. et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 380, 2095-2128 (2013).
2. Yang, S., Rothman, R. E. PCR-based diagnostics for infectious diseases: uses, limitations, future applications in acute-care settings. Lancet Infect Dis. 4, 337-348 (2004).
3. Kivity, S. et al. A novel automated indirect immunofluorescence autoantibody evaluation. Clin. rheumatol. 31, 503-509 (2012).
4. Wild, D. The Immunoassay Handbook: Theory and applications of ligand binding, ELISA and related techniques. (Newnes, 2013).
5. Fu, G., Sanjay, S. T., Dou, M., Li, X. J. Nanoparticle-mediated photothermal effect enables a new method for quantitative biochemical analysis using a thermometer. Nanoscale. 8, 5422-5427 (2016).
6. Verbarg, J. et al. Catch and release: Integrated system for multiplexed detection of bacteria. Anal. Chem. 85, 4944-4950 (2013).
7. Urdea, M. et al. Requirements for high impact diagnostics in the developing world. Nature 444, 73-79 (2006).
8. Kai, J. et al. A novel microfluidic microplate as the next generation assay platform for enzyme linked immunoassays (ELISA). Lab Chip. 12, 4257-4262 (2012).
9. Wang, H. et al. A Microfluidic Indirect Competitive Immunoassay for Multiple and Sensitive Detection of Testosterone in Serum and Urine. Analyst. 141, 815-819 (2016).
10. Chin, C. D. et al. Microfluidics-based diagnostics of infectious diseases in the developing world. Nature medicine 17, 1015-1019 (2011).
11. Sanjay, S. T. et al. Biomarker detection for disease diagnosis using cost-effective microfluidic platforms. Analyst 140, 7062-7081 (2015).
12. Dou, M., Sanjay, S. T., Benhabib, M., Xu, F., Li, X. Low-cost bioanalysis on paper-based and its hybrid microfluidic platforms. Talanta. 145, 43-54 (2015).
13. Li, X., Chen, Y., Li, P. C. A simple and fast microfluidic approach of same-single-cell analysis (SASCA) for the study of multidrug resistance modulation in cancer cells. Lab Chip 11, 1378-1384 (2011).
14. Li, X., Li, P. C. Strategies for the real-time detection of Ca2+ channel events of single cells: recent advances and new possibilities. Expert Rev Clin Pharmacol 3, 267-280 (2010).
15. Lee, G.-H. et al. Deformable L-shaped microwell array for trapping pairs of heterogeneous cells. J. Micromech. Microeng. 25, 035005 (2015).
16. Li, X., Valadez, A. V., Zuo, P., Nie, Z. Microfluidic 3D cell culture: potential application for tissue-based bioassays. Bioanalysis. 4, 1509-1525 (2012).
17. Liu, P., Li, X., Greenspoon, S. A., Scherer, J. R., Mathies, R. A. Integrated DNA purification, PCR, sample cleanup, capillary electrophoresis microchip for forensic human identification. Lab Chip. 11, 1041-1048 (2011).
18. Andersen, A. S. e., Zheng, W., Sutherland, D. S., Jiang, X. Versatile multiple protein nanopatterning within a microfluidic channel for cell recruitment studies. Lab Chip. 15, 4524-4532 (2015).
19. Lai, D., Takayama, S., Smith, G. D. Recent microfluidic devices for studying gamete and embryo biomechanics. J. Biomech. 48, 1671-1678 (2015).
20. Li, X. J., Zhou, Y. Microfluidic devices for biomedical applications. (Elsevier, 2013).
21. Roelofs, S. H., van den Berg, A., Odijk, M. Microfluidic desalination techniques and their potential applications. Lab Chip. 15, 3428-3438 (2015).
22. De, A., Sparreboom, W., van den Berg, A., Carlen, E. T. Rapid microfluidic solid-phase extraction system for hyper-methylated DNA enrichment and epigenetic analysis. Biomicrofluidics. 8, 054119 (2014).
23. Sapsford, K. E., Francis, J., Sun, S., Kostov, Y., Rasooly, A. Miniaturized 96-well ELISA chips for staphylococcal enterotoxin B detection using portable colorimetric detector. Anal. Bioanal chem. 394, 499-505 (2009).
24. Sun, S., Yang, M., Kostov, Y., Rasooly, A. ELISA-LOC: lab-on-a-chip for enzyme-linked immunodetection. Lab Chip. 10, 2093-2100 (2010).
25. Martinez, A. W., Phillips, S. T., Butte, M. J., Whitesides, G. M. Patterned paper as a platform for inexpensive, low?volume, portable bioassays. Angew. Chem. Int. Ed. 46, 1318-1320 (2007).
26. Martinez, A. W. Microfluidic paper-based analytical devices: from POCKET to paper-based ELISA. Bioanalysis 3, 2589-2592, doi: 10.4155/bio.11.258 (2011).
27. Li, Z. et al. Direct writing electrodes using a ball pen for paper-based point-of-care testing. Analyst 140, 5526-5535 (2015).
28. Cheng, C. M. et al. Paper-Based ELISA. Angew. Chem. Int. Ed. 49, 4771-4774 (2010).
29. Murdock, R. C. et al. Optimization of a paper-based ELISA for a human performance biomarker. Anal. chem. 85, 11634-11642 (2013).
30. Wang, S. et al. Paper-based chemiluminescence ELISA: lab-on-paper based on chitosan modified paper device and wax-screenprinting. Biosens. Bioelectron. 31, 212-218 (2012).
31. Lei, K. F. et al. Paper-based enzyme-free immunoassay for rapid detection and subtyping of influenza A H1N1 and H3N2 viruses. Anal. Chim. Acta. 883, 37-44 (2015).
32. Liu, Y. et al. Microchip-based ELISA strategy for the detection of low-level disease biomarker in serum. Anal. Chim. Acta. 650, 77-82 (2009).
33. Bai, Y. et al. Surface modification for enhancing antibody binding on polymer-based microfluidic device for enzyme-linked immunosorbent assay. Langmuir. 22, 9458-9467 (2006).
34. Darain, F., Wahab, M. A., Tjin, S. C. Surface Activation of Poly (Methyl methacrylate) by Plasma Treatment: Stable Antibody Immobilization for Microfluidic Enzyme-Linked Immunosorbent Assay. Anal. Lett. 45, 2569-2579 (2012).
35. Zuo, P., Li, X., Dominguez, D. C., Ye, B.-C. A PDMS/paper/glass hybrid microfluidic biochip integrated with aptamerfunctionalized graphene oxide nano-biosensors for one-step multiplexed pathogen detection. Lab Chip. 13, 3921-3928 (2013).
36. Dou, M., Dominguez, D. C., Li, X., Sanchez, J., Scott, G. A Versatile PDMS/Paper Hybrid Microfluidic Platform for Sensitive Infectious Disease Diagnosis. Anal. Chem. 86, 7978-7986 (2014).
37. Choi, J. R. et al. A PDMS-Paper Hybrid Lateral Flow Assay for Highly Sensitive Point-of-Care Nucleic Acid Testing. Anal. Chem, doi: 10.1021/acs.analchem.6b00195, (2016).
38. Choi, S., Park, J.-K. Two-step photolithography to fabricate multilevel microchannels. Biomicrofluidics 4, 046503 (2010).
39. Nam, K.-H., Eddington, D. T. Size-based separation of microparticles in a multilayered microfluidic device. J. Microelectromech. 19, 375-383 (2010).
40. Li, X., Huang, J., Tibbits, G. F., Li, P. C. Real?time monitoring of intracellular calcium dynamic mobilization of a single cardiomyocyte in a microfluidic chip pertaining to drug discovery. Electrophoresis 28, 4723-4733 (2007).
41. Yang, C.-S. et al. Femtosecond laser ablation of polymethylmethacrylate via dual-color synthesized waveform. Appl. Phys. Lett. 106, 051902 (2015).
42. Lakos, G. et al. Anti-cyclic citrullinated peptide antibody isotypes in rheumatoid arthritis: association with disease duration, rheumatoid factor production and the presence of shared epitope. Clin. Exp. Rheumatol. 26, 253 (2008).
43. Shors, T. Understanding viruses. (Jones & Bartlett Publishers, 2011).
44. Pittock, S. J. et al. Neuromyelitis optica and non-organ-specific autoimmunity. Arch. Neurol. 65, 78-83 (2008).
45. Zhang, S., Garcia-D'Angeli, A., Brennan, J. P., Huo, Q. Predicting detection limits of enzyme-linked immunosorbent assay (ELISA) and bioanalytical techniques in general. Analyst 139, 439-445 (2014).
46. Lai, C. L., Ratziu, V., Yuen, M.-F., Poynard, T. Viral hepatitis B. Lancet. 362, 2089-2094 (2003).
47. Rodella, A. et al. Quantitative analysis of HBsAg, IgM anti-HBc and anti-HBc avidity in acute and chronic hepatitis B. J. Clin. Virol. 37, 206-212 (2006).
48. Jaroszewicz, J. et al. Hepatitis B surface antigen (HBsAg) levels in the natural history of hepatitis B virus (HBV)-infection: a European perspective. J. Hepatol. 52, 514-522 (2010).
49. Ben Slama, N., Si Ahmed, S., Zoulim, F. Quantification de l'antig?e HBs: signification virologique. Gastroenterol. Clin. Biol. 34, S112-S118 (2010).
50. Ganem, D., Prince, A. M. Hepatitis B virus infection-natural history and clinical consequences. N. Engl. J. Med. 350, 1118-1129 (2004).
51. Yazdani, Y., Roohi, A., Khoshnoodi, J., Shokri, F. Development of a sensitive enzyme-linked immunosorbent assay for detection of hepatitis B surface antigen using novel monoclonal antibodies. Avicenna J Med Biotechnol. 2, 207-214 (2011).
52. van Amsterdam, P. et al. The European Bioanalysis Forum community's evaluation, interpretation and implementation of the European Medicines Agency guideline on Bioanalytical Method Validation. Bioanalysis 5, 645-659 (2013).
53. Fu, G., Sanjay, S. T., Li, X. Cost-effective and sensitive colorimetric immunosensing using an iron oxide-to-Prussian blue nanoparticle conversion strategy. Analyst, 141, 3883-3889 (2016).
54. Xu, X. et al. Advances in Smartphone-Based Point-of-Care Diagnostics. Proc. IEEE. 103, 236-247 (2015).