SIRT7 is a histone desuccinylase that functionally links to chromatin compaction and genome stability

Nature Communications

Volumn 7, Issue , 2016, Pages

  Li, Lei ^a   Shi, Lan ^a   Yang, Shangda ^b   Yan, Ruorong ^a   Zhang, Di ^a   Yang, Jianguo ^a   He, Lin ^a   Li, Wanjin ^a   Yi, Xia ^a   Sun, Luyang ^a   Liang, Jing ^a   Cheng, Zhongyi ^c   Shi, Lei ^b   Shang, Yongfeng ^a,b   Yu, Wenhua ^a  

^a PEKING UNIVERSITY   (China)

^b TIANJIN MEDICAL UNIVERSITY   (China)

^c Jingjie PTM BioLab (Hangzhou) Co Ltd   (China)

Author keywords

[No Author keywords available]

Indexed keywords

SIRTUIN 7; HISTONE; LYSINE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; SIRT7 PROTEIN, HUMAN; SIRTUIN; SUCCINIC ACID DERIVATIVE;

CATALYSIS; CELL ORGANELLE; DNA; ENZYME ACTIVITY; EXPERIMENTAL STUDY; GENE; GENETIC ANALYSIS; MOLECULAR ANALYSIS; PROTEIN;

ARTICLE; CATALYSIS; CELL FUNCTION; CELL SURVIVAL; CHROMATIN; CHROMATIN COMPACTION; CHROMATIN CONDENSATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA HISTONE INTERACTION; DNA REPAIR; DOUBLE STRANDED DNA BREAK; ENZYME ACTIVITY; EPIGENETICS; FEMALE; GENETIC REGULATION; GENOMIC INSTABILITY; HISTONE MODIFICATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MCF 7 CELL LINE; NUCLEOSOME; PROTEIN DEPLETION; PROTEIN EXPRESSION; U2OS CELL LINE; BIOCATALYSIS; CELL LINE; DNA DAMAGE; METABOLISM;

BIOCATALYSIS; CELL LINE; CELL SURVIVAL; CHROMATIN; DNA DAMAGE; DNA REPAIR; GENOMIC INSTABILITY; HISTONES; HUMANS; LYSINE; POLY(ADP-RIBOSE) POLYMERASES; SIRTUINS; SUCCINATES;

EID: 84979498569     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms12235     Document Type: Article

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