Cobalt-Catalyzed Oxidase C-H/N-H Alkyne Annulation: Mechanistic Insights and Access to Anticancer Agents

Chemistry - A European Journal

Volumn 22, Issue 20, 2016, Pages 6759-6763

  Mei, Ruhuai ^a   Wang, Hui ^a   Warratz, Svenja ^a   MacGregor, Stuart A ^b   Ackermann, Lutz ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b HERIOT WATT UNIVERSITY   (United Kingdom)

Author keywords

annulation; C H activation; cobalt; density functional calculations; isoquinolones; oxidase

Indexed keywords

ACTIVATION ANALYSIS; CATALYSIS; COBALT; DENSITY FUNCTIONAL THEORY;

ALKYNE INSERTIONS; ANNULATION; ANTI-CANCER AGENTS; C-H ACTIVATION; ELECTRONIC EFFECTS; FUNCTIONALIZATIONS; ISOQUINOLONES; OXIDASE;

HYDROCARBONS;

21,22-DIMETHOXYROSETTACIN; ALKYNE; ANTINEOPLASTIC AGENT; COBALT; COORDINATION COMPOUND; DNA TOPOISOMERASE INHIBITOR; FUSED HETEROCYCLIC RINGS; ISOQUINOLINE DERIVATIVE; OXIDOREDUCTASE;

CATALYSIS; CHEMISTRY; QUANTUM THEORY; STEREOISOMERISM; SYNTHESIS; THERMODYNAMICS;

ALKYNES; ANTINEOPLASTIC AGENTS; CATALYSIS; COBALT; COORDINATION COMPLEXES; HETEROCYCLIC COMPOUNDS, 4 OR MORE RINGS; ISOQUINOLINES; OXIDOREDUCTASES; QUANTUM THEORY; STEREOISOMERISM; THERMODYNAMICS; TOPOISOMERASE I INHIBITORS;

EID: 84979486449     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.201601101     Document Type: Article

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