The endothelial adaptor molecule TSAd is required for VEGF-induced angiogenic sprouting through junctional c-Src activation

Science Signaling

Volumn 9, Issue 437, 2016, Pages

  Gordon, Emma J ^a   Fukuhara, Daisuke ^a,e   Weström, Simone ^a   Padhan, Narendra ^a   Sjöström, Elisabet O ^a   Van Meeteren, Laurens ^a   He, Liqun ^a   Orsenigo, Fabrizio ^b   Dejana, Elisabetta ^a,b   Bentley, Katie ^a,c   Spurkland, Anne ^d   Lena, Claesson Welsh ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

^c HARVARD MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF OSLO   (Norway)

^e KYORIN UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

MATRIGEL; PROTEIN; PROTEIN SH2; SARACATINIB; SMALL INTERFERING RNA; T CELL SPECIFIC ADAPTOR PROTEIN; TAMOXIFEN; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 2; CSK TYROSINE-PROTEIN KINASE; KDR PROTEIN, MOUSE; PROTEIN TYROSINE KINASE; SH2D2A PROTEIN, MOUSE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; VASCULAR ENDOTHELIAL GROWTH FACTOR A, MOUSE; VASCULOTROPIN A;

ANGIOGENESIS; ANIMAL EXPERIMENT; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL ACTIVATION; CELL SELECTION; CONTROLLED STUDY; EMBRYOID BODY; ENDOTHELIUM; GENE ACTIVATION; MOUSE; NONHUMAN; ONCOGENE SRC; PRIORITY JOURNAL; PROTEIN LOCALIZATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SPROUTING; TRACHEAL BLOOD VESSEL; ANIMAL; CELL LINE; ENDOTHELIUM CELL; GENETICS; KNOCKOUT MOUSE; METABOLISM; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELL LINE; ENDOTHELIAL CELLS; MICE; MICE, KNOCKOUT; NEOVASCULARIZATION, PATHOLOGIC; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

EID: 84979287990     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.aad9256     Document Type: Article

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