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Volumn 15, Issue 3, 2014, Pages 223-230

Leukocyte extravasation and vascular permeability are each controlled in vivo by different tyrosine residues of VE-cadherin

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; ANTIGENS, CD; BENZETHONIUM; CADHERINS; CAPILLARY PERMEABILITY; CHEMOTAXIS, LEUKOCYTE; ENDOTHELIAL CELLS; FLUORESCENT ANTIBODY TECHNIQUE; GENE KNOCK-IN TECHNIQUES; HUMANS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MICE; MICE, INBRED C57BL; PHOSPHORYLATION; TYROSINE;

EID: 84894470051     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.2824     Document Type: Article
Times cited : (268)

References (40)
  • 1
    • 0032536833 scopus 로고    scopus 로고
    • Neutrophils emigrate from venules by a transendothelial cell pathway in response to FMLP
    • Feng, D., Nagy, J.A., Pyne, K., Dvorak, H.F. & Dvorak, A.M. Neutrophils emigrate from venules by a transendothelial cell pathway in response to FMLP. J. Exp. Med. 187, 903-915 (1998).
    • (1998) J. Exp. Med. , vol.187 , pp. 903-915
    • Feng, D.1    Nagy, J.A.2    Pyne, K.3    Dvorak, H.F.4    Dvorak, A.M.5
  • 2
    • 33644839612 scopus 로고    scopus 로고
    • Signaling Mechanisms regulating endothelial permeability
    • Mehta, D. & Malik, A.B. Signaling Mechanisms regulating endothelial permeability. Physiol. Rev. 86, 279-367 (2006).
    • (2006) Physiol. Rev. , vol.86 , pp. 279-367
    • Mehta, D.1    Malik, A.B.2
  • 3
    • 80054935637 scopus 로고    scopus 로고
    • Stabilizing the VE-cadherin-catenin complex blocks leukocyte extravasation and vascular permeability
    • Schulte, D. et al. Stabilizing the VE-cadherin-catenin complex blocks leukocyte extravasation and vascular permeability. EMBO J. 30, 4157-4170 (2011).
    • (2011) EMBO J. , vol.30 , pp. 4157-4170
    • Schulte, D.1
  • 4
    • 80052026271 scopus 로고    scopus 로고
    • The junctional adhesion molecule JAM-C regulates polarized transendothelial migration of neutrophils in vivo
    • Woodfin, A. et al. The junctional adhesion molecule JAM-C regulates polarized transendothelial migration of neutrophils in vivo. Nat. Immunol. 12, 761-769 (2011).
    • (2011) Nat. Immunol. , vol.12 , pp. 761-769
    • Woodfin, A.1
  • 5
    • 39849104321 scopus 로고    scopus 로고
    • Endothelial adherens and tight junctions in vascular homeostasis, inflammation and angiogenesis
    • Wallez, Y. & Huber, P. Endothelial adherens and tight junctions in vascular homeostasis, inflammation and angiogenesis. Biochim. Biophys. Acta 1778, 794-809 (2008).
    • (2008) Biochim. Biophys. Acta , vol.1778 , pp. 794-809
    • Wallez, Y.1    Huber, P.2
  • 6
    • 84855493801 scopus 로고    scopus 로고
    • Dissociation of VE-PTP from VE-cadherin is required for leukocyte extravasation and for VEGF-induced vascular permeability in vivo
    • Broermann, A. et al. Dissociation of VE-PTP from VE-cadherin is required for leukocyte extravasation and for VEGF-induced vascular permeability in vivo. J. Exp. Med. 208, 2393-2401 (2011).
    • (2011) J. Exp. Med. , vol.208 , pp. 2393-2401
    • Broermann, A.1
  • 7
    • 57749192473 scopus 로고    scopus 로고
    • And signaling of endothelial cell-to-cell junctions in various regions of the blood and lymphatic vascular trees
    • Dejana, E., Orsenigo, F., Molendini, C., Baluk, P. & McDonald, D.M. Organization and signaling of endothelial cell-to-cell junctions in various regions of the blood and lymphatic vascular trees. Cell Tissue Res. 335, 17-25 (2009).
    • (2009) Cell Tissue Res. , vol.335 , pp. 17-25
    • Dejana, E.1    Orsenigo, F.2    Molendini, C.3    Baluk, P.4    Organization, M.M.D.5
  • 8
    • 34249650761 scopus 로고    scopus 로고
    • The role of junctional adhesion molecules in vascular inflammation
    • Weber, C., Fraemohs, L. & Dejana, E. The role of junctional adhesion molecules in vascular inflammation. Nat. Rev. Immunol. 7, 467-477 (2007).
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 467-477
    • Weber, C.1    Fraemohs, L.2    Dejana, E.3
  • 9
    • 38549128935 scopus 로고    scopus 로고
    • The major endothelial adhesion molecule controlling cellular junctions and blood vessel formation
    • Vestweber, D. VE-cadherin: the major endothelial adhesion molecule controlling cellular junctions and blood vessel formation. Arterioscler. Thromb. Vasc. Biol. 28, 223-232 (2008).
    • (2008) Arterioscler. Thromb. Vasc. Biol. , vol.28 , pp. 223-232
    • Ve-Cadherin, V.D.1
  • 10
    • 0030907344 scopus 로고    scopus 로고
    • VE-cadherin antibody accelerates neutrophil recruiment in vivo
    • Gotsch, U. et al. VE-cadherin antibody accelerates neutrophil recruiment in vivo. J. Cell Sci. 110, 583-588 (1997).
    • (1997) J. Cell Sci. , vol.110 , pp. 583-588
    • Gotsch, U.1
  • 11
    • 13044264471 scopus 로고    scopus 로고
    • Vascular endothelial-cadherin is an important determinant of microvascular integrity in vivo
    • Corada, M. et al. Vascular endothelial-cadherin is an important determinant of microvascular integrity in vivo. Proc. Natl. Acad. Sci. USA 96, 9815-9820 (1999).
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 9815-9820
    • Corada, M.1
  • 12
    • 58149291905 scopus 로고    scopus 로고
    • VE-PTP maintains the endothelial barrier via plakoglobin and becomes dissociated from VE-cadherin by leukocytes and by VEGF
    • Nottebaum, A.F. et al. VE-PTP maintains the endothelial barrier via plakoglobin and becomes dissociated from VE-cadherin by leukocytes and by VEGF. J. Exp. Med. 205, 2929-2945 (2008).
    • (2008) J. Exp. Med. , vol.205 , pp. 2929-2945
    • Nottebaum, A.F.1
  • 13
    • 84862907457 scopus 로고    scopus 로고
    • VEGF-induced vascular permeability is mediated by FAK
    • Chen, X.L. et al. VEGF-induced vascular permeability is mediated by FAK. Dev. Cell 22, 146-157 (2012).
    • (2012) Dev. Cell , vol.22 , pp. 146-157
    • Chen, X.L.1
  • 14
    • 33750529948 scopus 로고    scopus 로고
    • VEGF controls endothelial-cell permeability by promoting the b-arrestin-dependent endocytosis of VE-cadherin
    • Gavard, J. & Gutkind, J.S. VEGF controls endothelial-cell permeability by promoting the b-arrestin-dependent endocytosis of VE-cadherin. Nat. Cell Biol. 8, 1223-1234 (2006).
    • (2006) Nat. Cell Biol. , vol.8 , pp. 1223-1234
    • Gavard, J.1    Gutkind, J.S.2
  • 15
    • 0031825437 scopus 로고    scopus 로고
    • Vascular endothelial growth factor induces VE-cadherin tyrosine phosphorylation in endothelial cells
    • Esser, S., Lampugnani, M.G., Corada, M., Dejana, E. & Risau, W. Vascular endothelial growth factor induces VE-cadherin tyrosine phosphorylation in endothelial cells. J. Cell Sci. 111, 1853-1865 (1998).
    • (1998) J. Cell Sci. , vol.111 , pp. 1853-1865
    • Esser, S.1    Lampugnani, M.G.2    Corada, M.3    Dejana, E.4    Risau, W.5
  • 17
    • 33845414929 scopus 로고    scopus 로고
    • TNF-alpha increases tyrosine phosphorylation of vascular endothelial cadherin and opens the paracellular pathway through fyn activation in human lung endothelia
    • Angelini, D.J. et al. TNF-alpha increases tyrosine phosphorylation of vascular endothelial cadherin and opens the paracellular pathway through fyn activation in human lung endothelia. Am. J. Physiol. Lung Cell. Mol. Physiol. 291, L1232-L1245 (2006).
    • (2006) Am. J. Physiol. Lung Cell. Mol. Physiol. , vol.291
    • Angelini, D.J.1
  • 18
    • 14044256553 scopus 로고    scopus 로고
    • Vascular endothelial-cadherin tyrosine phosphorylation in angiogenic and quiescent adult tissues
    • Lambeng, N. et al. Vascular endothelial-cadherin tyrosine phosphorylation in angiogenic and quiescent adult tissues. Circ. Res. 96, 384-391 (2005).
    • (2005) Circ. Res. , vol.96 , pp. 384-391
    • Lambeng, N.1
  • 19
    • 84870688010 scopus 로고    scopus 로고
    • Phosphorylation of VE-cadherin is modulated by haemodynamic forces and contributes to the regulation of vascular permeability in vivo
    • Orsenigo, F. et al. Phosphorylation of VE-cadherin is modulated by haemodynamic forces and contributes to the regulation of vascular permeability in vivo. Nat. Commun. 3, 1208 (2012).
    • (2012) Nat. Commun. , vol.3 , pp. 1208
    • Orsenigo, F.1
  • 20
    • 0033393771 scopus 로고    scopus 로고
    • Selective requirement for Src kinases during VEGF-induced angiogenesis and vascular permeability
    • Eliceiri, B.P. et al. Selective requirement for Src kinases during VEGF-induced angiogenesis and vascular permeability. Mol. Cell 4, 915-924 (1999).
    • (1999) Mol. Cell , vol.4 , pp. 915-924
    • Eliceiri, B.P.1
  • 21
    • 70350015332 scopus 로고    scopus 로고
    • The regulation of vascular endothelial growth factor-induced microvascular permeability requires Rac and reactive oxygen species
    • Monaghan-Benson, E. & Burridge, K. The regulation of vascular endothelial growth factor-induced microvascular permeability requires Rac and reactive oxygen species. J. Biol. Chem. 284, 25602-25611 (2009).
    • (2009) J. Biol. Chem. , vol.284 , pp. 25602-25611
    • Monaghan-Benson, E.1    Burridge, K.2
  • 22
    • 33847050140 scopus 로고    scopus 로고
    • Src kinase phosphorylates vascular endothelial-cadherin in response to vascular endothelial growth factor: Identification of tyrosine 685 as the unique target site
    • Wallez, Y. et al. Src kinase phosphorylates vascular endothelial-cadherin in response to vascular endothelial growth factor: identification of tyrosine 685 as the unique target site. Oncogene 26, 1067-1077 (2007).
    • (2007) Oncogene , vol.26 , pp. 1067-1077
    • Wallez, Y.1
  • 23
    • 35748948971 scopus 로고    scopus 로고
    • Src- and Pyk2-dependent vascular endothelial cadherin tyrosine phosphorylation is required for leukocyte transendothelial migration
    • Allingham, M.J., van Buul, J.D. & Burridge, K. ICAM-1-mediated, Src- and Pyk2-dependent vascular endothelial cadherin tyrosine phosphorylation is required for leukocyte transendothelial migration. J. Immunol. 179, 4053-4064 (2007).
    • (2007) J. Immunol. , vol.179 , pp. 4053-4064
    • Allingham, M.J.1    Van Buul, J.D.2    Icam-Mediated, B.K.3
  • 24
    • 38549169704 scopus 로고    scopus 로고
    • Phosphorylation of vascular endothelial cadherin controls lymphocyte emigration
    • Turowski, P. et al. Phosphorylation of vascular endothelial cadherin controls lymphocyte emigration. J. Cell Sci. 121, 29-37 (2008).
    • (2008) J. Cell Sci. , vol.121 , pp. 29-37
    • Turowski, P.1
  • 25
    • 77951212625 scopus 로고    scopus 로고
    • SRC-induced tyrosine phosphorylation of VE-cadherin is not sufficient to decrease barrier function of endothelial monolayers
    • Adam, A.P., Sharenko, A.L., Pumiglia, K. & Vincent, P.A. SRC-induced tyrosine phosphorylation of VE-cadherin is not sufficient to decrease barrier function of endothelial monolayers. J. Biol. Chem. 285, 7045-7055 (2010).
    • (2010) J. Biol. Chem. , vol.285 , pp. 7045-7055
    • Adam, A.P.1    Sharenko, A.L.2    Pumiglia, K.3    Vincent, P.A.4
  • 26
    • 36549052593 scopus 로고    scopus 로고
    • Clathrin-mediated endocytosis of a lipid-raft-associated protein is mediated through a dual tyrosine motif
    • Rollason, R., Korolchuk, V., Hamilton, C., Schu, P. & Banting, G. Clathrin-mediated endocytosis of a lipid-raft-associated protein is mediated through a dual tyrosine motif. J. Cell Sci. 120, 3850-3858 (2007).
    • (2007) J. Cell Sci. , vol.120 , pp. 3850-3858
    • Rollason, R.1    Korolchuk, V.2    Hamilton, C.3    Schu, P.4    Banting, G.5
  • 27
    • 67650120099 scopus 로고    scopus 로고
    • HM1.24 is internalized from lipid rafts by clathrin-mediated endocytosis through interaction with alpha-adaptin
    • Masuyama, N. et al. HM1.24 is internalized from lipid rafts by clathrin-mediated endocytosis through interaction with alpha-adaptin. J. Biol. Chem. 284, 15927-15941 (2009).
    • (2009) J. Biol. Chem. , vol.284 , pp. 15927-15941
    • Masuyama, N.1
  • 28
    • 18544390381 scopus 로고    scopus 로고
    • VE-PTP and VE-cadherin ectodomains interact to facilitate regulation of phosphorylation and cell contacts
    • Nawroth, R. et al. VE-PTP and VE-cadherin ectodomains interact to facilitate regulation of phosphorylation and cell contacts. EMBO J. 21, 4885-4895 (2002).
    • (2002) EMBO J. , vol.21 , pp. 4885-4895
    • Nawroth, R.1
  • 29
    • 0031750020 scopus 로고    scopus 로고
    • Endothelial gaps and adherent leukocytes in allergen-induced early- and late-phase plasma leakage in rat airways
    • Baluk, P., Bolton, P., Hirata, A., Thurston, G. & McDonald, D.M. Endothelial gaps and adherent leukocytes in allergen-induced early- and late-phase plasma leakage in rat airways. Am. J. Pathol. 152, 1463-1476 (1998).
    • (1998) Am. J. Pathol. , vol.152 , pp. 1463-1476
    • Baluk, P.1    Bolton, P.2    Hirata, A.3    Thurston, G.4    McDonald, D.M.5
  • 30
    • 24744449317 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of VE-cadherin prevents binding of p120- and beta-catenin and maintains the cellular mesenchymal state
    • Potter, M.D., Barbero, S. & Cheresh, D.A. Tyrosine phosphorylation of VE-cadherin prevents binding of p120- and beta-catenin and maintains the cellular mesenchymal state. J. Biol. Chem. 280, 31906-31912 (2005).
    • (2005) J. Biol. Chem. , vol.280 , pp. 31906-31912
    • Potter, M.D.1    Barbero, S.2    Cheresh, D.A.3
  • 31
    • 0031684385 scopus 로고    scopus 로고
    • T cell interaction with ICAM-1-deficient endothelium in vitro: Essential role for ICAM-1 and ICAM-2 in transendothelial migration of T cells
    • Reiss, Y., Hoch, G., Deutsch, U. & Engelhardt, B. T cell interaction with ICAM-1-deficient endothelium in vitro: essential role for ICAM-1 and ICAM-2 in transendothelial migration of T cells. Eur. J. Immunol. 28, 3086-3099 (1998).
    • (1998) Eur. J. Immunol. , vol.28 , pp. 3086-3099
    • Reiss, Y.1    Hoch, G.2    Deutsch, U.3    Engelhardt, B.4
  • 32
    • 0028605282 scopus 로고
    • Only simultaneous blocking of L- and P-selectin completely inhibits neutrophil migration into mouse petritoneum
    • Bosse, R. & Vestweber, D. Only simultaneous blocking of L- and P-selectin completely inhibits neutrophil migration into mouse petritoneum. Eur. J. Immunol. 24, 3019-3024 (1994).
    • (1994) Eur. J. Immunol. , vol.24 , pp. 3019-3024
    • Bosse, R.1    Vestweber, D.2
  • 33
    • 0026718810 scopus 로고
    • Cloning of the mouse endothelial selectins: Expression of both E- and P-selectin is inducible by tumor necrosis factor-α
    • Weller, A., Isenmann, S. & Vestweber, D. Cloning of the mouse endothelial selectins: Expression of both E- and P-selectin is inducible by tumor necrosis factor-α. J. Biol. Chem. 267, 15176-15183 (1992).
    • (1992) J. Biol. Chem. , vol.267 , pp. 15176-15183
    • Weller, A.1    Isenmann, S.2    Vestweber, D.3
  • 34
    • 33745813930 scopus 로고    scopus 로고
    • ESAM supports neutrophil extravasation, activation of Rho and VEGF-induced vascular permeability
    • Wegmann, F. et al. ESAM supports neutrophil extravasation, activation of Rho and VEGF-induced vascular permeability. J. Exp. Med. 203, 1671-1677 (2006).
    • (2006) J. Exp. Med. , vol.203 , pp. 1671-1677
    • Wegmann, F.1
  • 35
    • 0034623082 scopus 로고    scopus 로고
    • Junctional adhesion molecule (JAM) interacts with the PDZ domain containing proteins AF-6 and ZO
    • Ebnet, K., Schulz, C.U., Meyer-zu-Brickwedde, M.-K., Pendl, G.G. & Vestweber, D. Junctional adhesion molecule (JAM) interacts with the PDZ domain containing proteins AF-6 and ZO. J. Biol. Chem. 275, 27979-27988 (2000).
    • (2000) J. Biol. Chem. , vol.275 , pp. 27979-27988
    • Ebnet, K.1    Schulz, C.U.2    Meyer-Zu-Brickwedde, M.-K.3    Pendl, G.G.4    Vestweber, D.5
  • 36
    • 34250004353 scopus 로고    scopus 로고
    • A CD99-related antigen on endothelial cells mediates neutrophil but not lymphocyte extravasation in vivo
    • Bixel, M.G. et al. A CD99-related antigen on endothelial cells mediates neutrophil but not lymphocyte extravasation in vivo. Blood 109, 5327-5336 (2007).
    • (2007) Blood , vol.109 , pp. 5327-5336
    • Bixel, M.G.1
  • 37
    • 34250180872 scopus 로고    scopus 로고
    • Spleen tyrosine kinase Syk is necessary for E-selectin-induced αlβ2 integrin-mediated rolling on intercellular adhesion molecule
    • Zarbock, A., Lowell, C.A. & Ley, K. Spleen tyrosine kinase Syk is necessary for E-selectin-induced αLβ2 integrin-mediated rolling on intercellular adhesion molecule. Immunity 26, 773-783 (2007).
    • (2007) Immunity , vol.26 , pp. 773-783
    • Zarbock, A.1    Lowell, C.A.2    Ley, K.3
  • 38
    • 52949125597 scopus 로고    scopus 로고
    • Therapeutic inhibition of CXCR2 by Reparixin attenuates acute lung injury in mice
    • Zarbock, A., Allegretti, M. & Ley, K. Therapeutic inhibition of CXCR2 by Reparixin attenuates acute lung injury in mice. Br. J. Pharmacol. 155, 357-364 (2008).
    • (2008) Br. J. Pharmacol. , vol.155 , pp. 357-364
    • Zarbock, A.1    Allegretti, M.2    Ley, K.3
  • 39
    • 0345689431 scopus 로고    scopus 로고
    • Visualization of leukocyte transendothelial and interstitial migration using reflected light oblique transillumination in intravital video microscopy
    • Mempel, T.R., Moser, C., Hutter, J., Kuebler, W.M. & Krombach, F. Visualization of leukocyte transendothelial and interstitial migration using reflected light oblique transillumination in intravital video microscopy. J. Vasc. Res. 40, 435-441 (2003).
    • (2003) J. Vasc. Res. , vol.40 , pp. 435-441
    • Mempel, T.R.1    Moser, C.2    Hutter, J.3    Kuebler, W.M.4    Krombach, F.5
  • 40
    • 0242456021 scopus 로고    scopus 로고
    • Cellular levels of p120 catenin function as a set point for cadherin expression levels in microvascular endothelial cells
    • Xiao, K. et al. Cellular levels of p120 catenin function as a set point for cadherin expression levels in microvascular endothelial cells. J. Cell Biol. 163, 535-545 (2003).
    • (2003) J. Cell Biol. , vol.163 , pp. 535-545
    • Xiao, K.1


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