-
1
-
-
84880742193
-
Signal transduction by vascular endothelial growth factor receptors
-
Koch S, Claesson-Welsh L (2012) Signal transduction by vascular endothelial growth factor receptors. Cold Spring Harb Perspect Med 2(7):a006502.
-
(2012)
Cold Spring Harb Perspect Med
, vol.2
, Issue.7
, pp. a006502
-
-
Koch, S.1
Claesson-Welsh, L.2
-
2
-
-
0029006696
-
Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice
-
Shalaby F, et al. (1995) Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice. Nature 376(6535):62-66.
-
(1995)
Nature
, vol.376
, Issue.6535
, pp. 62-66
-
-
Shalaby, F.1
-
3
-
-
33847666928
-
Antiangiogenesis to treat cancer and intraocular neovascular disorders
-
Shojaei F, Ferrara N (2007) Antiangiogenesis to treat cancer and intraocular neovascular disorders. Lab Invest 87(3):227-230.
-
(2007)
Lab Invest
, vol.87
, Issue.3
, pp. 227-230
-
-
Shojaei, F.1
Ferrara, N.2
-
4
-
-
0032582502
-
Cardiovascular failure in mouse embryos deficient in VEGF receptor-3
-
Dumont DJ, et al. (1998) Cardiovascular failure in mouse embryos deficient in VEGF receptor-3. Science 282(5390):946-949.
-
(1998)
Science
, vol.282
, Issue.5390
, pp. 946-949
-
-
Dumont, D.J.1
-
5
-
-
0028938746
-
Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development
-
Kaipainen A, et al. (1995) Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development. Proc Natl Acad Sci USA 92(8):3566-3570.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, Issue.8
, pp. 3566-3570
-
-
Kaipainen, A.1
-
6
-
-
0033814892
-
VEGF-C and VEGF-D expression in neuroendocrine cells and their receptor, VEGFR-3, in fenestrated blood vessels in human tissues
-
Partanen TA, et al. (2000) VEGF-C and VEGF-D expression in neuroendocrine cells and their receptor, VEGFR-3, in fenestrated blood vessels in human tissues. FASEB J 14(13): 2087-2096.
-
(2000)
FASEB J
, vol.14
, Issue.13
, pp. 2087-2096
-
-
Partanen, T.A.1
-
7
-
-
48349129069
-
Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation
-
Tammela T, et al. (2008) Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation. Nature 454(7204):656-660.
-
(2008)
Nature
, vol.454
, Issue.7204
, pp. 656-660
-
-
Tammela, T.1
-
8
-
-
33847039645
-
Notch signalling limits angiogenic cell behaviour in developing zebrafish arteries
-
Siekmann AF, Lawson ND (2007) Notch signalling limits angiogenic cell behaviour in developing zebrafish arteries. Nature 445(7129):781-784.
-
(2007)
Nature
, vol.445
, Issue.7129
, pp. 781-784
-
-
Siekmann, A.F.1
Lawson, N.D.2
-
9
-
-
0032933883
-
VEGFR-3 and its ligand VEGF-C are associated with angiogenesis in breast cancer
-
Valtola R, et al. (1999) VEGFR-3 and its ligand VEGF-C are associated with angiogenesis in breast cancer. Am J Pathol 154(5):1381-1390.
-
(1999)
Am J Pathol
, vol.154
, Issue.5
, pp. 1381-1390
-
-
Valtola, R.1
-
10
-
-
0033846016
-
Vascular endothelial growth factor receptor-3 in lymphangiogenesis in wound healing
-
Paavonen K, Puolakkainen P, Jussila L, Jahkola T, Alitalo K (2000) Vascular endothelial growth factor receptor-3 in lymphangiogenesis in wound healing. Am J Pathol 156(5): 1499-1504.
-
(2000)
Am J Pathol
, vol.156
, Issue.5
, pp. 1499-1504
-
-
Paavonen, K.1
Puolakkainen, P.2
Jussila, L.3
Jahkola, T.4
Alitalo, K.5
-
11
-
-
80052015813
-
Molecular control of endothelial cell behaviour during blood vessel morphogenesis
-
Herbert SP, Stainier DY (2011) Molecular control of endothelial cell behaviour during blood vessel morphogenesis. Nat Rev Mol Cell Biol 12(9):551-564.
-
(2011)
Nat Rev Mol Cell Biol
, vol.12
, Issue.9
, pp. 551-564
-
-
Herbert, S.P.1
Stainier, D.Y.2
-
12
-
-
33847635620
-
Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting
-
Lobov IB, et al. (2007) Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting. Proc Natl Acad Sci USA 104(9):3219-3224.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.9
, pp. 3219-3224
-
-
Lobov, I.B.1
-
13
-
-
33847607880
-
The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching
-
Suchting S, et al. (2007) The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching. Proc Natl Acad Sci USA 104(9):3225-3230.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.9
, pp. 3225-3230
-
-
Suchting, S.1
-
14
-
-
77957607057
-
Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting
-
Jakobsson L, et al. (2010) Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting. Nat Cell Biol 12(10):943-953.
-
(2010)
Nat Cell Biol
, vol.12
, Issue.10
, pp. 943-953
-
-
Jakobsson, L.1
-
15
-
-
25444506836
-
Up-regulation of delta-like 4 ligand in human tumor vasculature and the role of basal expression in endothelial cell function
-
Patel NS, et al. (2005) Up-regulation of delta-like 4 ligand in human tumor vasculature and the role of basal expression in endothelial cell function. Cancer Res 65(19): 8690-8697.
-
(2005)
Cancer Res
, vol.65
, Issue.19
, pp. 8690-8697
-
-
Patel, N.S.1
-
16
-
-
80053564674
-
VEGFR-3 controls tip to stalk conversion at vessel fusion sites by reinforcing Notch signalling
-
Tammela T, et al. (2011) VEGFR-3 controls tip to stalk conversion at vessel fusion sites by reinforcing Notch signalling. Nat Cell Biol 13(10):1202-1213.
-
(2011)
Nat Cell Biol
, vol.13
, Issue.10
, pp. 1202-1213
-
-
Tammela, T.1
-
17
-
-
36048978608
-
Notch alters VEGF responsiveness in human and murine endothelial cells by direct regulation of VEGFR-3 expression
-
Shawber CJ, et al. (2007) Notch alters VEGF responsiveness in human and murine endothelial cells by direct regulation of VEGFR-3 expression. J Clin Invest 117(11): 3369-3382.
-
(2007)
J Clin Invest
, vol.117
, Issue.11
, pp. 3369-3382
-
-
Shawber, C.J.1
-
18
-
-
33646228404
-
Distinct genetic interactions between multiple Vegf receptors are required for development of different blood vessel types in zebrafish
-
Covassin LD, Villefranc JA, Kacergis MC, Weinstein BM, Lawson ND (2006) Distinct genetic interactions between multiple Vegf receptors are required for development of different blood vessel types in zebrafish. Proc Natl Acad Sci USA 103(17): 6554-6559.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, Issue.17
, pp. 6554-6559
-
-
Covassin, L.D.1
Villefranc, J.A.2
Kacergis, M.C.3
Weinstein, B.M.4
Lawson, N.D.5
-
19
-
-
77951498501
-
VEGF receptor 2/-3 heterodimers detected in situ by proximity ligation on angiogenic sprouts
-
Nilsson I, et al. (2010) VEGF receptor 2/-3 heterodimers detected in situ by proximity ligation on angiogenic sprouts. EMBO J 29(8):1377-1388.
-
(2010)
EMBO J
, vol.29
, Issue.8
, pp. 1377-1388
-
-
Nilsson, I.1
-
20
-
-
84859453770
-
Notch-dependent VEGFR3 upregulation allows angiogenesis without VEGF-VEGFR2 signalling
-
Benedito R, et al. (2012) Notch-dependent VEGFR3 upregulation allows angiogenesis without VEGF-VEGFR2 signalling. Nature 484(7392):110-114.
-
(2012)
Nature
, vol.484
, Issue.7392
, pp. 110-114
-
-
Benedito, R.1
-
21
-
-
39549098360
-
Efficient, inducible Cre-recombinase activation in vascular endothelium
-
Claxton S, et al. (2008) Efficient, inducible Cre-recombinase activation in vascular endothelium. Genesis 46(2):74-80.
-
(2008)
Genesis
, vol.46
, Issue.2
, pp. 74-80
-
-
Claxton, S.1
-
22
-
-
77953029002
-
Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis
-
Wang Y, et al. (2010) Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis. Nature 465(7297):483-486.
-
(2010)
Nature
, vol.465
, Issue.7297
, pp. 483-486
-
-
Wang, Y.1
-
23
-
-
0141503519
-
Cortical and retinal defects caused by dosage-dependent reductions in VEGF-A paracrine signaling
-
Haigh JJ, et al. (2003) Cortical and retinal defects caused by dosage-dependent reductions in VEGF-A paracrine signaling. Dev Biol 262(2):225-241.
-
(2003)
Dev Biol
, vol.262
, Issue.2
, pp. 225-241
-
-
Haigh, J.J.1
-
24
-
-
47949083776
-
Deletion of vascular endothelial growth factor C (VEGF-C) and VEGF-D is not equivalent to VEGF receptor 3 deletion in mouse embryos
-
Haiko P, et al. (2008) Deletion of vascular endothelial growth factor C (VEGF-C) and VEGF-D is not equivalent to VEGF receptor 3 deletion in mouse embryos. Mol Cell Biol 28(15):4843-4850.
-
(2008)
Mol Cell Biol
, vol.28
, Issue.15
, pp. 4843-4850
-
-
Haiko, P.1
-
25
-
-
0027997863
-
Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor
-
Waltenberger J, Claesson-Welsh L, Siegbahn A, Shibuya M, Heldin CH (1994) Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor. J Biol Chem 269(43):26988-26995.
-
(1994)
J Biol Chem
, vol.269
, Issue.43
, pp. 26988-26995
-
-
Waltenberger, J.1
Claesson-Welsh, L.2
Siegbahn, A.3
Shibuya, M.4
Heldin, C.H.5
-
26
-
-
0037815292
-
VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia
-
Gerhardt H, et al. (2003) VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia. J Cell Biol 161(6):1163-1177.
-
(2003)
J Cell Biol
, vol.161
, Issue.6
, pp. 1163-1177
-
-
Gerhardt, H.1
-
27
-
-
0034778258
-
Notch signaling is required for arterial-venous differentiation during embryonic vascular development
-
Lawson ND, et al. (2001) Notch signaling is required for arterial-venous differentiation during embryonic vascular development. Development 128(19):3675-3683.
-
(2001)
Development
, vol.128
, Issue.19
, pp. 3675-3683
-
-
Lawson, N.D.1
-
28
-
-
5444261424
-
Dosage-sensitive requirement for mouse Dll4 in artery development
-
Duarte A, et al. (2004) Dosage-sensitive requirement for mouse Dll4 in artery development. Genes Dev 18(20):2474-2478.
-
(2004)
Genes Dev
, vol.18
, Issue.20
, pp. 2474-2478
-
-
Duarte, A.1
-
29
-
-
63649138023
-
Arterial-venous specification during development
-
Swift MR, Weinstein BM (2009) Arterial-venous specification during development. Circ Res 104(5):576-588.
-
(2009)
Circ Res
, vol.104
, Issue.5
, pp. 576-588
-
-
Swift, M.R.1
Weinstein, B.M.2
-
30
-
-
60849138787
-
Engraftment and reconstitution of hematopoiesis is dependent on VEGFR2-mediated regeneration of sinusoidal endothelial cells
-
Hooper AT, et al. (2009) Engraftment and reconstitution of hematopoiesis is dependent on VEGFR2-mediated regeneration of sinusoidal endothelial cells. Cell Stem Cell 4(3):263-274.
-
(2009)
Cell Stem Cell
, vol.4
, Issue.3
, pp. 263-274
-
-
Hooper, A.T.1
-
31
-
-
84908281444
-
Neurons limit angiogenesis by titrating VEGF in retina
-
Okabe K, et al. (2014) Neurons limit angiogenesis by titrating VEGF in retina. Cell 159(3):584-596.
-
(2014)
Cell
, vol.159
, Issue.3
, pp. 584-596
-
-
Okabe, K.1
-
32
-
-
58149154746
-
Delta-like 4 is indispensable in thymic environment specific for T cell development
-
Hozumi K, et al. (2008) Delta-like 4 is indispensable in thymic environment specific for T cell development. J Exp Med 205(11):2507-2513.
-
(2008)
J Exp Med
, vol.205
, Issue.11
, pp. 2507-2513
-
-
Hozumi, K.1
-
33
-
-
33847046849
-
Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis
-
Hellström M, et al. (2007) Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis. Nature 445(7129):776-780.
-
(2007)
Nature
, vol.445
, Issue.7129
, pp. 776-780
-
-
Hellström, M.1
-
34
-
-
59649085554
-
Angiogenesis: A team effort coordinated by notch
-
Phng LK, Gerhardt H (2009) Angiogenesis: A team effort coordinated by notch. Dev Cell 16(2):196-208.
-
(2009)
Dev Cell
, vol.16
, Issue.2
, pp. 196-208
-
-
Phng, L.K.1
Gerhardt, H.2
-
35
-
-
84878362932
-
G13 controls angiogenesis through regulation of VEGFR-2 expression
-
Sivaraj KK, et al. (2013) G13 controls angiogenesis through regulation of VEGFR-2 expression. Dev Cell 25(4):427-434.
-
(2013)
Dev Cell
, vol.25
, Issue.4
, pp. 427-434
-
-
Sivaraj, K.K.1
-
36
-
-
0029839804
-
Flk-1, a receptor for vascular endothelial growth factor (VEGF), is expressed by retinal progenitor cells
-
Yang X, Cepko CL (1996) Flk-1, a receptor for vascular endothelial growth factor (VEGF), is expressed by retinal progenitor cells. J Neurosci 16(19):6089-6099.
-
(1996)
J Neurosci
, vol.16
, Issue.19
, pp. 6089-6099
-
-
Yang, X.1
Cepko, C.L.2
-
37
-
-
8644290828
-
Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development
-
Gale NW, et al. (2004) Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development. Proc Natl Acad Sci USA 101(45):15949-15954.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.45
, pp. 15949-15954
-
-
Gale, N.W.1
-
38
-
-
80255135606
-
Endothelial basement membrane limits tip cell formation by inducing Dll4/Notch signalling in vivo
-
Stenzel D, et al. (2011) Endothelial basement membrane limits tip cell formation by inducing Dll4/Notch signalling in vivo. EMBO Rep 12(11):1135-1143.
-
(2011)
EMBO Rep
, vol.12
, Issue.11
, pp. 1135-1143
-
-
Stenzel, D.1
-
39
-
-
79960357259
-
Laminin-binding integrins induce Dll4 expression and Notch signaling in endothelial cells
-
Estrach S, et al. (2011) Laminin-binding integrins induce Dll4 expression and Notch signaling in endothelial cells. Circ Res 109(2):172-182.
-
(2011)
Circ Res
, vol.109
, Issue.2
, pp. 172-182
-
-
Estrach, S.1
-
40
-
-
20444495706
-
Cell-autonomous notch signaling regulates endothelial cell branching and proliferation during vascular tubulogenesis
-
Sainson RC, et al. (2005) Cell-autonomous notch signaling regulates endothelial cell branching and proliferation during vascular tubulogenesis. FASEB J 19(8):1027-1029.
-
(2005)
FASEB J
, vol.19
, Issue.8
, pp. 1027-1029
-
-
Sainson, R.C.1
|