Rapamycin versus intermittent feeding: Dissociable effects on physiological and behavioral outcomes when initiated early and late in life

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 71, Issue 7, 2016, Pages 866-875

  Carter, Christy S ^a   Khamiss, Dallas ^a   Matheny, Michael ^a   Toklu, Hale Z ^a   Kirichenko, Nataliya ^a   Strehler, Kevin Y E ^a   Tümer, Nihal ^a,b   Scarpace, Philip J ^a   Morgan, Drake ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Calorie restriction; Healthspan; Leptin; Life span; mTOR; p70S6K; Physical function

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; IMMUNOSUPPRESSIVE AGENT; LEPTIN; RAPAMYCIN; TARGET OF RAPAMYCIN KINASE;

AGING; ANIMAL; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; DRUG EFFECTS; FOOD INTAKE; LONGEVITY; MALE; METABOLISM; PHYSIOLOGY; PROCEDURES; PSYCHOLOGY; RAT; SIGNAL TRANSDUCTION; TREATMENT OUTCOME;

AGING; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; BEHAVIOR, ANIMAL; FEEDING METHODS; IMMUNOSUPPRESSIVE AGENTS; LEPTIN; LONGEVITY; MALE; PHYSICAL CONDITIONING, ANIMAL; RATS; SIGNAL TRANSDUCTION; SIROLIMUS; TOR SERINE-THREONINE KINASES; TREATMENT OUTCOME;

EID: 84979240900     PISSN: 10795006     EISSN: 1758535X     Source Type: Journal    
DOI: 10.1093/gerona/glu238     Document Type: Article

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