Impaired 2-AG signaling in hippocampal glutamatergic neurons: Aggravation of anxiety-like behavior and unaltered seizure susceptibility

International Journal of Neuropsychopharmacology

Volumn 19, Issue 2, 2016, Pages 1-13

  Guggenhuber, Stephan ^a   Romo Parra, Hector ^b   Bindila, Laura ^a   Leschik, Julia ^a   Lomazzo, Ermelinda ^a   Remmers, Floortje ^a   Zimmermann, Tina ^a   Lerner, Raissa ^a   Klugmann, Matthias ^a,c   Pape, Hans Christian ^b   Lutz, Beat ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b UNIVERSITY OF MÜNSTER   (Germany)

^c UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

Anxiety; Endocannabinoids; Epilepsy; Hippocampus; Monoacylglycerol lipase

Indexed keywords

2 ARACHIDONOYLGLYCEROL; ACYLGLYCEROL LIPASE; PARVOVIRUS VECTOR; ACYLGLYCEROL; ARACHIDONIC ACID DERIVATIVE; ENDOCANNABINOID; GLUTAMIC ACID; GLYCERYL 2-ARACHIDONATE;

ADULT; ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY; ARTICLE; BRAIN REGION; CONTROLLED STUDY; DEPOLARIZATION; DNA MODIFICATION; ENZYME DEGRADATION; ENZYME INHIBITION; GLUTAMATERGIC SYNAPSE; HIPPOCAMPUS; MALE; MOUSE; NERVE CELL; NERVE CELL STIMULATION; NONHUMAN; PRESYNAPTIC NERVE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; SEIZURE SUSCEPTIBILITY; SIGNAL TRANSDUCTION; ANIMAL; C57BL MOUSE; METABOLISM; PHYSIOLOGY; PSYCHOLOGY; SEIZURE;

ANIMALS; ANXIETY; ARACHIDONIC ACIDS; ENDOCANNABINOIDS; GLUTAMIC ACID; GLYCERIDES; HIPPOCAMPUS; MALE; MICE; MICE, INBRED C57BL; NEURONS; SEIZURES; SIGNAL TRANSDUCTION;

EID: 84979234623     PISSN: 14611457     EISSN: 14695111     Source Type: Journal    
DOI: 10.1093/ijnp/pyv091     Document Type: Article

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