메뉴 건너뛰기




Volumn 79, Issue 10, 2016, Pages 858-868

Anxiety, Stress, and Fear Response in Mice with Reduced Endocannabinoid Levels

Author keywords

Anxiety; Cannabinoids; Dagla; Depression; Fear extinction; Stress

Indexed keywords

2 ARACHIDONOYLGLYCEROL; ANANDAMIDE; BROXURIDINE; CANNABINOID 1 RECEPTOR; DIACYLGLYCEROL LIPASE ALPHA; ENDOCANNABINOID; LIPOPROTEIN LIPASE; UNCLASSIFIED DRUG;

EID: 84929094440     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2015.03.033     Document Type: Article
Times cited : (139)

References (43)
  • 1
    • 4544275181 scopus 로고    scopus 로고
    • The endocannabinoid system and its therapeutic exploitation
    • V. Di Marzo, M. Bifulco, and L. De Petrocellis The endocannabinoid system and its therapeutic exploitation Nat Rev Drug Discov 3 2004 771 784
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 771-784
    • Di Marzo, V.1    Bifulco, M.2    De Petrocellis, L.3
  • 2
    • 10744229235 scopus 로고    scopus 로고
    • Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain
    • T. Bisogno, F. Howell, G. Williams, A. Minassi, M.G. Cascio, A. Ligresti, and et al. Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain J Cell Biol 163 2003 463 468
    • (2003) J Cell Biol , vol.163 , pp. 463-468
    • Bisogno, T.1    Howell, F.2    Williams, G.3    Minassi, A.4    Cascio, M.G.5    Ligresti, A.6
  • 4
    • 47749088572 scopus 로고    scopus 로고
    • A diacylglycerol lipase-CB2 cannabinoid pathway regulates adult subventricular zone neurogenesis in an age-dependent manner
    • M.B. Goncalves, P. Suetterlin, P. Yip, F. Molina-Holgado, D.J. Walker, M.J. Oudin, and et al. A diacylglycerol lipase-CB2 cannabinoid pathway regulates adult subventricular zone neurogenesis in an age-dependent manner Mol Cell Neurosci 38 2008 526 536
    • (2008) Mol Cell Neurosci , vol.38 , pp. 526-536
    • Goncalves, M.B.1    Suetterlin, P.2    Yip, P.3    Molina-Holgado, F.4    Walker, D.J.5    Oudin, M.J.6
  • 5
    • 76649137560 scopus 로고    scopus 로고
    • Loss of retrograde endocannabinoid signaling and reduced adult neurogenesis in diacylglycerol lipase knock-out mice
    • Y. Gao, D.V. Vasilyev, M.B. Goncalves, F.V. Howell, C. Hobbs, M. Reisenberg, and et al. Loss of retrograde endocannabinoid signaling and reduced adult neurogenesis in diacylglycerol lipase knock-out mice J Neurosci 30 2010 2017 2024
    • (2010) J Neurosci , vol.30 , pp. 2017-2024
    • Gao, Y.1    Vasilyev, D.V.2    Goncalves, M.B.3    Howell, F.V.4    Hobbs, C.5    Reisenberg, M.6
  • 6
    • 75949116246 scopus 로고    scopus 로고
    • The endocannabinoid 2-arachidomoylglycerol produced by diacylglycerol lipase α mediates retrograde suppression of synaptic transmission
    • A. Tanimura, M. Yamazaki, Y. Hashimotodani, M. Uchigashima, S. Kawata, A. Manube, and et al. The endocannabinoid 2-arachidomoylglycerol produced by diacylglycerol lipase α mediates retrograde suppression of synaptic transmission Neuron 25 2010 320 327
    • (2010) Neuron , vol.25 , pp. 320-327
    • Tanimura, A.1    Yamazaki, M.2    Hashimotodani, Y.3    Uchigashima, M.4    Kawata, S.5    Manube, A.6
  • 7
    • 36048995288 scopus 로고    scopus 로고
    • Effiacy and safety of of the weight-loss drug rimonabant: A meta-analysis of randomised trials
    • R. Christensen, P. Kruse Kristensen, E.M. Bartels, H. Bliddal, and A. Astrup Effiacy and safety of of the weight-loss drug rimonabant: A meta-analysis of randomised trials Lancet 370 2007 1706 1713
    • (2007) Lancet , vol.370 , pp. 1706-1713
    • Christensen, R.1    Kruse Kristensen, P.2    Bartels, E.M.3    Bliddal, H.4    Astrup, A.5
  • 9
    • 84857128654 scopus 로고    scopus 로고
    • 1 receptor-deficient mice as a model for depression
    • 1 receptor-deficient mice as a model for depression Neuroscience 204 2012 193 206
    • (2012) Neuroscience , vol.204 , pp. 193-206
    • Valverde, O.1    Torrens, M.2
  • 10
    • 20344374645 scopus 로고    scopus 로고
    • Prevalence, severity and comorbidity of twelve-month DSM-IV disorders in the National Comorbidity Survey Replication (NCS-R)
    • R.C. Kessler, W. Chiu, O. Demler, and E.E. Walters Prevalence, severity and comorbidity of twelve-month DSM-IV disorders in the National Comorbidity Survey Replication (NCS-R) Arch Gen Psychiatry 62 2005 617 627
    • (2005) Arch Gen Psychiatry , vol.62 , pp. 617-627
    • Kessler, R.C.1    Chiu, W.2    Demler, O.3    Walters, E.E.4
  • 11
    • 12844281785 scopus 로고    scopus 로고
    • Depression and cardiovascular disease: A call for recognition
    • J.S. Rumsfeld, and M. Ho Depression and cardiovascular disease: A call for recognition Circulation 111 2005 250 253
    • (2005) Circulation , vol.111 , pp. 250-253
    • Rumsfeld, J.S.1    Ho, M.2
  • 12
    • 23644431529 scopus 로고    scopus 로고
    • The stress system in the human brain in depression an neurodegeneration
    • D.F. Swaab, A.-M. Bao, and P.J. Lucassen The stress system in the human brain in depression an neurodegeneration Ageing Res Rev 4 2005 141 194
    • (2005) Ageing Res Rev , vol.4 , pp. 141-194
    • Swaab, D.F.1    Bao, A.-M.2    Lucassen, P.J.3
  • 13
    • 33749120752 scopus 로고    scopus 로고
    • Approaching the shared biology of obesity and depression: The stress axis as the locus of gene-environment interactions
    • S.R. Bornstein, A. Schuppenies, M.-L. Wong, and J. Licinio Approaching the shared biology of obesity and depression: the stress axis as the locus of gene-environment interactions Mol Psychiatry 11 2006 892 902
    • (2006) Mol Psychiatry , vol.11 , pp. 892-902
    • Bornstein, S.R.1    Schuppenies, A.2    Wong, M.-L.3    Licinio, J.4
  • 14
    • 0030638601 scopus 로고    scopus 로고
    • The effects of stressful life events on depression
    • R.C. Kessler The effects of stressful life events on depression Annu Rev Psychol 48 1997 191 214
    • (1997) Annu Rev Psychol , vol.48 , pp. 191-214
    • Kessler, R.C.1
  • 15
    • 36549030795 scopus 로고    scopus 로고
    • Stress, depression, and neuroplasticity: A convergence of mechanisms
    • C. Pittenger, and R.S. Duman Stress, depression, and neuroplasticity: A convergence of mechanisms Neuropsychopharmacology 33 2008 88 109
    • (2008) Neuropsychopharmacology , vol.33 , pp. 88-109
    • Pittenger, C.1    Duman, R.S.2
  • 16
    • 45149111341 scopus 로고    scopus 로고
    • Adaptations in endocannabinoid signaling in response to repeated homotypic stress: A novel mechanism for stress habituation
    • S. Patel, and C.J. Hillard Adaptations in endocannabinoid signaling in response to repeated homotypic stress: A novel mechanism for stress habituation Eur J Neurosci 27 2008 2821 2829
    • (2008) Eur J Neurosci , vol.27 , pp. 2821-2829
    • Patel, S.1    Hillard, C.J.2
  • 17
    • 0032030846 scopus 로고    scopus 로고
    • Maternally expressed PGK-Cre transgene as a tool for early and uniform activation oft he Cre site-specific recombinase
    • Y. Lallemand, V. Luria, R. Haffner-Krausz, and P. Lonai Maternally expressed PGK-Cre transgene as a tool for early and uniform activation oft he Cre site-specific recombinase Transgen Res 7 1998 105 112
    • (1998) Transgen Res , vol.7 , pp. 105-112
    • Lallemand, Y.1    Luria, V.2    Haffner-Krausz, R.3    Lonai, P.4
  • 18
    • 84925296781 scopus 로고    scopus 로고
    • Therapeutic potential of inhibitors of endocannabinoid degradation for the treatment of stress-related hyperalgesia in an animal model of chronic pain
    • E. Lomazzo, L. Bindila, F. Remmers, R. Lerner, C. Schwitter, U. Hoheisel, and B. Lutz Therapeutic potential of inhibitors of endocannabinoid degradation for the treatment of stress-related hyperalgesia in an animal model of chronic pain Neuropsychopharmacology. 40 2014 488 501
    • (2014) Neuropsychopharmacology , vol.40 , pp. 488-501
    • Lomazzo, E.1    Bindila, L.2    Remmers, F.3    Lerner, R.4    Schwitter, C.5    Hoheisel, U.6    Lutz, B.7
  • 19
    • 0036682222 scopus 로고    scopus 로고
    • The endogenous cannabinoid system controls extinction of aversive memories
    • G. Marsicano, C.T. Wotjak, S.C. Azad, T. Bisogno, G. Rammes, and M.G. Cascio The endogenous cannabinoid system controls extinction of aversive memories Nature 418 2002 530 534
    • (2002) Nature , vol.418 , pp. 530-534
    • Marsicano, G.1    Wotjak, C.T.2    Azad, S.C.3    Bisogno, T.4    Rammes, G.5    Cascio, M.G.6
  • 20
    • 33846478897 scopus 로고    scopus 로고
    • Mechanisms of fear extinction
    • K.M. Myers, and M. Davis Mechanisms of fear extinction Mol Psychiatry 12 2007 120 150
    • (2007) Mol Psychiatry , vol.12 , pp. 120-150
    • Myers, K.M.1    Davis, M.2
  • 21
    • 77956181836 scopus 로고    scopus 로고
    • Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system
    • J.E. Schlosburg, J.L. Blankman, J.Z. Long, D.K. Nomura, B. Pan, S.G. Kinsey, and et al. Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system Nat Neurosci 13 2010 1113 1119
    • (2010) Nat Neurosci , vol.13 , pp. 1113-1119
    • Schlosburg, J.E.1    Blankman, J.L.2    Long, J.Z.3    Nomura, D.K.4    Pan, B.5    Kinsey, S.G.6
  • 22
    • 81055156684 scopus 로고    scopus 로고
    • Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation
    • D.K. Nomura, B.E. Morrison, J.L. Blankman, J.Z. Long, S.G. Kinsey, M.C.G. Marcondes, and et al. Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation Science 334 2011 809 813
    • (2011) Science , vol.334 , pp. 809-813
    • Nomura, D.K.1    Morrison, B.E.2    Blankman, J.L.3    Long, J.Z.4    Kinsey, S.G.5    Marcondes, M.C.G.6
  • 23
    • 84875911353 scopus 로고    scopus 로고
    • A novel fluorophosphonate inhibitor of the biosynthesis of the endocannabinoid 2-arachidonoylglycerol with potential anti-obesity effects
    • T. Bisogno, A. Mahadevan, R. Coccurello, J.W. Chang, M. Allara, Y. Chen, and et al. A novel fluorophosphonate inhibitor of the biosynthesis of the endocannabinoid 2-arachidonoylglycerol with potential anti-obesity effects Br J Pharmacol 169 2013 784 793
    • (2013) Br J Pharmacol , vol.169 , pp. 784-793
    • Bisogno, T.1    Mahadevan, A.2    Coccurello, R.3    Chang, J.W.4    Allara, M.5    Chen, Y.6
  • 28
    • 79959977058 scopus 로고    scopus 로고
    • Enhancement of endocannabinoid signaling with JZL184, an inhibitor of the 2-arachidonoylglycerol hydrolyzing enzyme monoacylglycerol lipase, produces anxiolytic effects under conditions of high environmental aversiveness in rats
    • N.R. Sciolino, W. Zhou, and A.G. Hohmann Enhancement of endocannabinoid signaling with JZL184, an inhibitor of the 2-arachidonoylglycerol hydrolyzing enzyme monoacylglycerol lipase, produces anxiolytic effects under conditions of high environmental aversiveness in rats Pharmacol Res 64 2011 226 234
    • (2011) Pharmacol Res , vol.64 , pp. 226-234
    • Sciolino, N.R.1    Zhou, W.2    Hohmann, A.G.3
  • 30
    • 81355147886 scopus 로고    scopus 로고
    • 1 receptors impairs maternal behavior as well as offspring development and their adult social-emotional behavior
    • 1 receptors impairs maternal behavior as well as offspring development and their adult social-emotional behavior Behav Brain Res 226 2012 481 492
    • (2012) Behav Brain Res , vol.226 , pp. 481-492
    • Schechter, M.1    Pinhasov, A.2    Weller, A.3    Fride, E.4
  • 31
    • 84883813418 scopus 로고    scopus 로고
    • Endocannabinoid receptor deficiency affects maternal care and alters the dam's hippocampal oxytocin receptor and brain-derived neurothrophic factor expression
    • M. Schechter, A. Weller, P. Zittel, M. Gross, A. Zimmer, and A. Pinhasov Endocannabinoid receptor deficiency affects maternal care and alters the dam's hippocampal oxytocin receptor and brain-derived neurothrophic factor expression J Neuroendocrinology 25 2013 898 909
    • (2013) J Neuroendocrinology , vol.25 , pp. 898-909
    • Schechter, M.1    Weller, A.2    Zittel, P.3    Gross, M.4    Zimmer, A.5    Pinhasov, A.6
  • 32
    • 79952115483 scopus 로고    scopus 로고
    • Integration of endocannabinoid signaling into the neural network regulating stress-induced activation of the hypothalamic-pituitary-adrenal axis
    • B.B. Gorzalka, and M.N. Hill Integration of endocannabinoid signaling into the neural network regulating stress-induced activation of the hypothalamic-pituitary-adrenal axis Curr Top Behav Neurosci 1 2009 289 306
    • (2009) Curr Top Behav Neurosci , vol.1 , pp. 289-306
    • Gorzalka, B.B.1    Hill, M.N.2
  • 33
    • 84900565127 scopus 로고    scopus 로고
    • Monoacylglycerol lipase inhibition blocks chronic stress-induced depressive-like behaviors via activation of mTOR signaling
    • P. Zhong, W. Wang, B. Pan, X. Liu, Z. Zhang, J.Z. Long, and et al. Monoacylglycerol lipase inhibition blocks chronic stress-induced depressive-like behaviors via activation of mTOR signaling Neurpsychopharmacology 39 2014 1763 1776
    • (2014) Neurpsychopharmacology , vol.39 , pp. 1763-1776
    • Zhong, P.1    Wang, W.2    Pan, B.3    Liu, X.4    Zhang, Z.5    Long, J.Z.6
  • 34
    • 84916935127 scopus 로고    scopus 로고
    • Blockade of 2-arachidonoylglycerol hydrolysis produces antidepressant-like effects and enhances adult hippocampal neurogenesis and synaptic plasticity
    • Z. Zhang, W. Wang, P. Zhong, S.J. Liu, J.Z. Long, L. Zhao, and et al. Blockade of 2-arachidonoylglycerol hydrolysis produces antidepressant-like effects and enhances adult hippocampal neurogenesis and synaptic plasticity Hippocampus. 25 2014 16 26
    • (2014) Hippocampus , vol.25 , pp. 16-26
    • Zhang, Z.1    Wang, W.2    Zhong, P.3    Liu, S.J.4    Long, J.Z.5    Zhao, L.6
  • 35
    • 84903819476 scopus 로고    scopus 로고
    • Antidepressants and changes in concentration of endocannabinoids and N-acylethanolamines in rat brain structures
    • I. Smaga, B. Bystrowska, D. Gawlinski, B. Pomierny, P. Stankowicz, and M. Filip Antidepressants and changes in concentration of endocannabinoids and N-acylethanolamines in rat brain structures Neurotox Res 26 2014 190 206
    • (2014) Neurotox Res , vol.26 , pp. 190-206
    • Smaga, I.1    Bystrowska, B.2    Gawlinski, D.3    Pomierny, B.4    Stankowicz, P.5    Filip, M.6
  • 36
    • 41149130214 scopus 로고    scopus 로고
    • Serum endocannabinoid content is altered in females with depressive disorders: A preliminary report
    • M.N. Hill, G.E. Miller, V. Ho, B.B. Gorzalka, and C.J. Hillard Serum endocannabinoid content is altered in females with depressive disorders: A preliminary report Pharmacopsychiatry 41 2008 48 53
    • (2008) Pharmacopsychiatry , vol.41 , pp. 48-53
    • Hill, M.N.1    Miller, G.E.2    Ho, V.3    Gorzalka, B.B.4    Hillard, C.J.5
  • 37
    • 67650617724 scopus 로고    scopus 로고
    • Circulating endocannabinoids and N-acylethanolamines are differentially regulated in major depression and following exposure to social stress
    • M.N. Hill, G.E. Miller, E.J. Carrier, B.B. Gorzalka, and C.J. Hillard Circulating endocannabinoids and N-acylethanolamines are differentially regulated in major depression and following exposure to social stress Psychoneuroendocrinology 34 2009 1257 1262
    • (2009) Psychoneuroendocrinology , vol.34 , pp. 1257-1262
    • Hill, M.N.1    Miller, G.E.2    Carrier, E.J.3    Gorzalka, B.B.4    Hillard, C.J.5
  • 38
    • 10044272343 scopus 로고    scopus 로고
    • Nonassociative learning processes determine expression and extinction of conditioned fear in mice
    • K. Kamprath, and C.T. Wotjak Nonassociative learning processes determine expression and extinction of conditioned fear in mice Learn Mem 11 2004 770 786
    • (2004) Learn Mem , vol.11 , pp. 770-786
    • Kamprath, K.1    Wotjak, C.T.2
  • 39
    • 80055112984 scopus 로고    scopus 로고
    • The endocannabinoid system in anxiety, fear memory and habituation
    • S. Ruehle, A.A. Rey, F. Remmers, and B. Lutz The endocannabinoid system in anxiety, fear memory and habituation J Psychopharmacology 26 2012 23 39
    • (2012) J Psychopharmacology , vol.26 , pp. 23-39
    • Ruehle, S.1    Rey, A.A.2    Remmers, F.3    Lutz, B.4
  • 41
    • 37349065102 scopus 로고    scopus 로고
    • Effects of acute and repeated restraint stress on endocannabinoid content in the amygdala, ventral striatum, and medial prefrontal cortex in mice
    • D.J. Rademacher, S.E. Meier, L. Shi, W.S. Ho, A. Jarrahian, and C.J. Hillard Effects of acute and repeated restraint stress on endocannabinoid content in the amygdala, ventral striatum, and medial prefrontal cortex in mice Neuropsychopharmacology 54 2008 108 116
    • (2008) Neuropsychopharmacology , vol.54 , pp. 108-116
    • Rademacher, D.J.1    Meier, S.E.2    Shi, L.3    Ho, W.S.4    Jarrahian, A.5    Hillard, C.J.6
  • 42
    • 0035491607 scopus 로고    scopus 로고
    • Conditional control of gene expression
    • M. Lewandoski Conditional control of gene expression Nature Rev Genetics 2 2001 743 755
    • (2001) Nature Rev Genetics , vol.2 , pp. 743-755
    • Lewandoski, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.