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Volumn 34, Issue 7, 2016, Pages 1836-1845

Mesenchymal Stem Cells Induce Suppressive Macrophages Through Phagocytosis in a Mouse Model of Asthma

Author keywords

Airway hyper responsiveness; Airway smooth muscle contraction; House dust mite asthma; M2 macrophage; Mesenchymal stem cells; Phagocytosis

Indexed keywords

CARBACHOL; FLUORESCENT DYE; MUSCARINIC M2 RECEPTOR;

EID: 84979082255     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.2344     Document Type: Article
Times cited : (130)

References (48)
  • 1
    • 36348977575 scopus 로고    scopus 로고
    • Immunomodulatory properties of mesenchymal stromal cells
    • Nauta AJ, Fibbe WE. Immunomodulatory properties of mesenchymal stromal cells. Blood 2007;110:3499-3506.
    • (2007) Blood , vol.110 , pp. 3499-3506
    • Nauta, A.J.1    Fibbe, W.E.2
  • 2
    • 35448996504 scopus 로고    scopus 로고
    • Immunomodulation by mesenchymal stem cells and clinical experience
    • Le Blanc K, Ringden O. Immunomodulation by mesenchymal stem cells and clinical experience. J Intern Med 2007;262:509-525.
    • (2007) J Intern Med , vol.262 , pp. 509-525
    • Le Blanc, K.1    Ringden, O.2
  • 3
    • 2342482526 scopus 로고    scopus 로고
    • Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells
    • Le Blanc K, Rasmusson I, Sundberg B et al. Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells. Lancet 2004;363:1439-1441.
    • (2004) Lancet , vol.363 , pp. 1439-1441
    • Le Blanc, K.1    Rasmusson, I.2    Sundberg, B.3
  • 4
    • 70249122431 scopus 로고    scopus 로고
    • Immunomodulatory function of bone marrow-derived mesenchymal stem cells in experimental autoimmune type 1 diabetes
    • Fiorina P, Jurewicz M, Augello A et al. Immunomodulatory function of bone marrow-derived mesenchymal stem cells in experimental autoimmune type 1 diabetes. J Immunol 2009;183:993-1004.
    • (2009) J Immunol , vol.183 , pp. 993-1004
    • Fiorina, P.1    Jurewicz, M.2    Augello, A.3
  • 5
    • 70349881103 scopus 로고    scopus 로고
    • Mesenchymal stromal cells ameliorate experimental autoimmune encephalomyelitis by inhibiting CD4 Th17 T cells in a CC chemokine ligand 2-dependent manner
    • Rafei M, Campeau PM, Aguilar-Mahecha A et al. Mesenchymal stromal cells ameliorate experimental autoimmune encephalomyelitis by inhibiting CD4 Th17 T cells in a CC chemokine ligand 2-dependent manner. J Immunol 2009;182:5994-6002.
    • (2009) J Immunol , vol.182 , pp. 5994-6002
    • Rafei, M.1    Campeau, P.M.2    Aguilar-Mahecha, A.3
  • 6
    • 84885087642 scopus 로고    scopus 로고
    • Mesenchymal stem cell therapy in lung disorders: Pathogenesis of lung diseases and mechanism of action of mesenchymal stem cell
    • Inamdar AC, Inamdar AA. Mesenchymal stem cell therapy in lung disorders: Pathogenesis of lung diseases and mechanism of action of mesenchymal stem cell. Exp Lung Res 2013;39:315-327.
    • (2013) Exp Lung Res , vol.39 , pp. 315-327
    • Inamdar, A.C.1    Inamdar, A.A.2
  • 7
    • 84891800634 scopus 로고    scopus 로고
    • Concise review: Current status of stem cells and regenerative medicine in lung biology and diseases
    • Weiss DJ. Concise review: Current status of stem cells and regenerative medicine in lung biology and diseases. Stem Cells 2014;32:16-25.
    • (2014) Stem Cells , vol.32 , pp. 16-25
    • Weiss, D.J.1
  • 8
    • 84978970021 scopus 로고    scopus 로고
    • CgWS
    • https://clinicaltrials.gov/ct2/results?term=injection+of+mesenchymal+stem+cells&Search=Search CgWS.
  • 9
    • 77950377767 scopus 로고    scopus 로고
    • Bone marrow stromal cells use TGF-beta to suppress allergic responses in a mouse model of ragweed-induced asthma
    • Nemeth K, Keane-Myers A, Brown JM et al. Bone marrow stromal cells use TGF-beta to suppress allergic responses in a mouse model of ragweed-induced asthma. Proc Natl Acad Sci USA 2010;107:5652-5657.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 5652-5657
    • Nemeth, K.1    Keane-Myers, A.2    Brown, J.M.3
  • 10
    • 84856631196 scopus 로고    scopus 로고
    • Airway delivery of soluble factors from plastic-adherent bone marrow cells prevents murine asthma
    • Ionescu LI, Alphonse RS, Arizmendi N et al. Airway delivery of soluble factors from plastic-adherent bone marrow cells prevents murine asthma. Am J Respir Cell Mol Biol 2012;46:207-216.
    • (2012) Am J Respir Cell Mol Biol , vol.46 , pp. 207-216
    • Ionescu, L.I.1    Alphonse, R.S.2    Arizmendi, N.3
  • 11
    • 79960081138 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stromal cells inhibit Th2-mediated allergic airways inflammation in mice
    • Goodwin M, Sueblinvong V, Eisenhauer P et al. Bone marrow-derived mesenchymal stromal cells inhibit Th2-mediated allergic airways inflammation in mice. Stem Cells 2011;29:1137-1148.
    • (2011) Stem Cells , vol.29 , pp. 1137-1148
    • Goodwin, M.1    Sueblinvong, V.2    Eisenhauer, P.3
  • 12
    • 77956261268 scopus 로고    scopus 로고
    • Adipose-derived stromal cells inhibit allergic airway inflammation in mice
    • Park HK, Cho KS, Park HY et al. Adipose-derived stromal cells inhibit allergic airway inflammation in mice. Stem Cells Dev 2010;19:1811-188.
    • (2010) Stem Cells Dev , vol.19 , pp. 1188-1811
    • Park, H.K.1    Cho, K.S.2    Park, H.Y.3
  • 13
    • 79952042164 scopus 로고    scopus 로고
    • Allogeneic mesenchymal stem cells prevent allergic airway inflammation by inducing murine regulatory T cells
    • Kavanagh H, Mahon BP. Allogeneic mesenchymal stem cells prevent allergic airway inflammation by inducing murine regulatory T cells. Allergy 2011;66:523-531.
    • (2011) Allergy , vol.66 , pp. 523-531
    • Kavanagh, H.1    Mahon, B.P.2
  • 14
    • 82755177356 scopus 로고    scopus 로고
    • Suppression of allergic airway inflammation in a mouse model of asthma by exogenous mesenchymal stem cells
    • Ou-Yang HF, Huang Y, Hu XB et al. Suppression of allergic airway inflammation in a mouse model of asthma by exogenous mesenchymal stem cells. Exp Biol Med (Maywood) 2011;236:1461-1467.
    • (2011) Exp Biol Med (Maywood) , vol.236 , pp. 1461-1467
    • Ou-Yang, H.F.1    Huang, Y.2    Hu, X.B.3
  • 15
    • 84890376753 scopus 로고    scopus 로고
    • Alveolar macrophages are critical for the inhibition of allergic asthma by mesenchymal stromal cells
    • Mathias LJ, Khong SM, Spyroglou L et al. Alveolar macrophages are critical for the inhibition of allergic asthma by mesenchymal stromal cells. J Immunol 2013;191:5914-5924.
    • (2013) J Immunol , vol.191 , pp. 5914-5924
    • Mathias, L.J.1    Khong, S.M.2    Spyroglou, L.3
  • 16
    • 79957619269 scopus 로고    scopus 로고
    • Concise review: Mesenchymal stem cells for acute lung injury: Role of paracrine soluble factors
    • Lee JW, Fang X, Krasnodembskaya A et al. Concise review: Mesenchymal stem cells for acute lung injury: Role of paracrine soluble factors. Stem Cells 2011;29:913-919.
    • (2011) Stem Cells , vol.29 , pp. 913-919
    • Lee, J.W.1    Fang, X.2    Krasnodembskaya, A.3
  • 17
    • 58149326737 scopus 로고    scopus 로고
    • Bone marrow stromal cells attenuate sepsis via prostaglandin E(2)-dependent reprogramming of host macrophages to increase their interleukin-10 production
    • Nemeth K, Leelahavanichkul A, Yuen PS et al. Bone marrow stromal cells attenuate sepsis via prostaglandin E(2)-dependent reprogramming of host macrophages to increase their interleukin-10 production. Nat Med 2009;15:42-49.
    • (2009) Nat Med , vol.15 , pp. 42-49
    • Nemeth, K.1    Leelahavanichkul, A.2    Yuen, P.S.3
  • 18
    • 84866636444 scopus 로고    scopus 로고
    • Human mesenchymal stem/stromal cells cultured as spheroids are self-activated to produce prostaglandin E2 that directs stimulated macrophages into an anti-inflammatory phenotype
    • Ylostalo JH, Bartosh TJ, Coble K et al. Human mesenchymal stem/stromal cells cultured as spheroids are self-activated to produce prostaglandin E2 that directs stimulated macrophages into an anti-inflammatory phenotype. Stem Cells 2012;30:2283-2296.
    • (2012) Stem Cells , vol.30 , pp. 2283-2296
    • Ylostalo, J.H.1    Bartosh, T.J.2    Coble, K.3
  • 19
    • 84938944316 scopus 로고    scopus 로고
    • Prime role of IL-17A in neutrophilia and airway smooth muscle contraction in a house dust mite-induced allergic asthma model
    • Chesne J, Braza F, Chadeuf G et al. Prime role of IL-17A in neutrophilia and airway smooth muscle contraction in a house dust mite-induced allergic asthma model. J Allergy Clin Immunol 2015;135:1643-1645, e5.
    • (2015) J Allergy Clin Immunol , vol.135 , pp. 1643-1645
    • Chesne, J.1    Braza, F.2    Chadeuf, G.3
  • 20
    • 77951667958 scopus 로고    scopus 로고
    • Regulatory B cells prevent and reverse allergic airway inflammation via FoxP3-positive T regulatory cells in a murine model
    • Amu S, Saunders SP, Kronenberg M et al. Regulatory B cells prevent and reverse allergic airway inflammation via FoxP3-positive T regulatory cells in a murine model. J Allergy Clin Immunol 2010;125:1114-1124, e8.
    • (2010) J Allergy Clin Immunol , vol.125 , pp. 1114-1124
    • Amu, S.1    Saunders, S.P.2    Kronenberg, M.3
  • 21
    • 84857883847 scopus 로고    scopus 로고
    • Macrophage plasticity and polarization: In vivo veritas
    • Sica A, Mantovani A. Macrophage plasticity and polarization: In vivo veritas. J Clin Invest 2012;122:787-795.
    • (2012) J Clin Invest , vol.122 , pp. 787-795
    • Sica, A.1    Mantovani, A.2
  • 22
    • 84886443738 scopus 로고    scopus 로고
    • Concise review: Two negative feedback loops place mesenchymal stem/stromal cells at the center of early regulators of inflammation
    • Prockop DJ. Concise review: Two negative feedback loops place mesenchymal stem/stromal cells at the center of early regulators of inflammation. Stem Cells 2013;31:2042-2046.
    • (2013) Stem Cells , vol.31 , pp. 2042-2046
    • Prockop, D.J.1
  • 23
    • 78649809743 scopus 로고    scopus 로고
    • Human mesenchymal stem cells suppress chronic airway inflammation in the murine ovalbumin asthma model
    • Bonfield TL, Koloze M, Lennon DP et al. Human mesenchymal stem cells suppress chronic airway inflammation in the murine ovalbumin asthma model. Am J Physiol Lung Cell Mol Physiol 2010;299:L760-L770.
    • (2010) Am J Physiol Lung Cell Mol Physiol , vol.299 , pp. 760-770
    • Bonfield, T.L.1    Koloze, M.2    Lennon, D.P.3
  • 24
    • 84870362545 scopus 로고    scopus 로고
    • Human pluripotent stem cell-derived mesenchymal stem cells prevent allergic airway inflammation in mice
    • Sun YQ, Deng MX, He J et al. Human pluripotent stem cell-derived mesenchymal stem cells prevent allergic airway inflammation in mice. Stem Cells 2012;30:2692-2699.
    • (2012) Stem Cells , vol.30 , pp. 2692-2699
    • Sun, Y.Q.1    Deng, M.X.2    He, J.3
  • 25
    • 38349064863 scopus 로고    scopus 로고
    • Therapeutic potential of stem cells in lung disease: Progress and pitfalls
    • Loebinger MR, Aguilar S, Janes SM. Therapeutic potential of stem cells in lung disease: Progress and pitfalls. Clin Sci (Lond) 2008;114:99-108.
    • (2008) Clin Sci (Lond) , vol.114 , pp. 99-108
    • Loebinger, M.R.1    Aguilar, S.2    Janes, S.M.3
  • 26
    • 35348855644 scopus 로고    scopus 로고
    • Limitations of green fluorescent protein as a cell lineage marker
    • Swenson ES, Price JG, Brazelton T et al. Limitations of green fluorescent protein as a cell lineage marker. Stem Cells 2007;25:2593-2600.
    • (2007) Stem Cells , vol.25 , pp. 2593-2600
    • Swenson, E.S.1    Price, J.G.2    Brazelton, T.3
  • 27
    • 84856488316 scopus 로고    scopus 로고
    • Progress in gene and cell therapy for cystic fibrosis lung disease
    • Griesenbach U, Alton EW. Progress in gene and cell therapy for cystic fibrosis lung disease. Curr Pharm Des 2012;18:642-662.
    • (2012) Curr Pharm Des , vol.18 , pp. 642-662
    • Griesenbach, U.1    Alton, E.W.2
  • 28
    • 84875910318 scopus 로고    scopus 로고
    • Effects of intratracheal mesenchymal stromal cell therapy during recovery and resolution after ventilator-induced lung injury
    • Curley GF, Ansari B, Hayes M et al. Effects of intratracheal mesenchymal stromal cell therapy during recovery and resolution after ventilator-induced lung injury. Anesthesiology 2013;118:924-932.
    • (2013) Anesthesiology , vol.118 , pp. 924-932
    • Curley, G.F.1    Ansari, B.2    Hayes, M.3
  • 30
    • 84879363528 scopus 로고    scopus 로고
    • Adult stem cells for acute lung injury: Remaining questions and concerns
    • Zhu YG, Hao Q, Monsel A et al. Adult stem cells for acute lung injury: Remaining questions and concerns. Respirology 2013;18:744-756.
    • (2013) Respirology , vol.18 , pp. 744-756
    • Zhu, Y.G.1    Hao, Q.2    Monsel, A.3
  • 32
    • 22044458500 scopus 로고    scopus 로고
    • Engraftment of bone marrow-derived epithelial cells
    • Krause DS. Engraftment of bone marrow-derived epithelial cells. Ann NY Acad Sci 2005;1044:117-124.
    • (2005) Ann NY Acad Sci , vol.1044 , pp. 117-124
    • Krause, D.S.1
  • 33
    • 33749513225 scopus 로고    scopus 로고
    • Engraftment of donor-derived epithelial cells in multiple organs following bone marrow transplantation into newborn mice
    • Bruscia EM, Ziegler EC, Price JE et al. Engraftment of donor-derived epithelial cells in multiple organs following bone marrow transplantation into newborn mice. Stem Cells 2006;24:2299-2308.
    • (2006) Stem Cells , vol.24 , pp. 2299-2308
    • Bruscia, E.M.1    Ziegler, E.C.2    Price, J.E.3
  • 34
    • 31944451977 scopus 로고    scopus 로고
    • Limited restoration of cystic fibrosis lung epithelium in vivo with adult bone marrow-derived cells
    • Loi R, Beckett T, Goncz KK et al. Limited restoration of cystic fibrosis lung epithelium in vivo with adult bone marrow-derived cells. Am J Respir Crit Care Med 2006;173:171-179.
    • (2006) Am J Respir Crit Care Med , vol.173 , pp. 171-179
    • Loi, R.1    Beckett, T.2    Goncz, K.K.3
  • 35
    • 84915748427 scopus 로고    scopus 로고
    • Alveolar macrophages are sentinels of murine pulmonary homeostasis following inhaled antigen challenge
    • Mathie SA, Dixon KL, Walker SA et al. Alveolar macrophages are sentinels of murine pulmonary homeostasis following inhaled antigen challenge. Allergy 2015;70:80-89.
    • (2015) Allergy , vol.70 , pp. 80-89
    • Mathie, S.A.1    Dixon, K.L.2    Walker, S.A.3
  • 36
    • 84907485553 scopus 로고    scopus 로고
    • Resident alveolar macrophages suppress, whereas recruited monocytes promote, allergic lung inflammation in murine models of asthma
    • Zaslona Z, Przybranowski S, Wilke C et al. Resident alveolar macrophages suppress, whereas recruited monocytes promote, allergic lung inflammation in murine models of asthma. J Immunol 2014;193:4245-4253.
    • (2014) J Immunol , vol.193 , pp. 4245-4253
    • Zaslona, Z.1    Przybranowski, S.2    Wilke, C.3
  • 37
    • 78549291553 scopus 로고    scopus 로고
    • Cell distribution after intracoronary bone marrow stem cell delivery in damaged and undamaged myocardium: Implications for clinical trials
    • Forest VF, Tirouvanziam AM, Perigaud C et al. Cell distribution after intracoronary bone marrow stem cell delivery in damaged and undamaged myocardium: Implications for clinical trials. Stem Cell Res Ther 2010;1:4.
    • (2010) Stem Cell Res Ther , vol.1 , pp. 4
    • Forest, V.F.1    Tirouvanziam, A.M.2    Perigaud, C.3
  • 38
    • 84859015846 scopus 로고    scopus 로고
    • Medical therapies with adult stem/progenitor cells (MSCs): A backward journey from dramatic results in vivo to the cellular and molecular explanations
    • Prockop DJ, Oh JY. Medical therapies with adult stem/progenitor cells (MSCs): A backward journey from dramatic results in vivo to the cellular and molecular explanations. J Cell Biochem 2012;113:1460-1469.
    • (2012) J Cell Biochem , vol.113 , pp. 1460-1469
    • Prockop, D.J.1    Oh, J.Y.2
  • 39
    • 67349204472 scopus 로고    scopus 로고
    • Repair of tissues by adult stem/progenitor cells (MSCs): Controversies, myths, and changing paradigms
    • Prockop DJ. Repair of tissues by adult stem/progenitor cells (MSCs): Controversies, myths, and changing paradigms. Mol Ther 2009;17:939-946.
    • (2009) Mol Ther , vol.17 , pp. 939-946
    • Prockop, D.J.1
  • 40
    • 84939885072 scopus 로고    scopus 로고
    • Mesenchymal stem cells alleviate experimental asthma by inducing polarization of alveolar macrophages
    • Song X, Xie S, Lu K et al. Mesenchymal stem cells alleviate experimental asthma by inducing polarization of alveolar macrophages. Inflammation 2015;38:485-492.
    • (2015) Inflammation , vol.38 , pp. 485-492
    • Song, X.1    Xie, S.2    Lu, K.3
  • 41
    • 84870239895 scopus 로고    scopus 로고
    • Exosomes mediate the cytoprotective action of mesenchymal stromal cells on hypoxia-induced pulmonary hypertension
    • Lee C, Mitsialis SA, Aslam M et al. Exosomes mediate the cytoprotective action of mesenchymal stromal cells on hypoxia-induced pulmonary hypertension. Circulation 2012;126:2601-2611.
    • (2012) Circulation , vol.126 , pp. 2601-2611
    • Lee, C.1    Mitsialis, S.A.2    Aslam, M.3
  • 42
    • 84943795327 scopus 로고    scopus 로고
    • Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs
    • Phinney DG, Di Giuseppe M, Njah J et al. Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs. Nat Commun 2015;6:8472.
    • (2015) Nat Commun , vol.6 , pp. 8472
    • Phinney, D.G.1    Di Giuseppe, M.2    Njah, J.3
  • 43
    • 84877269319 scopus 로고    scopus 로고
    • Role of m2 muscarinic receptor in the airway response to methacholine of mice selected for minimal or maximal acute inflammatory response
    • Castro JM, Resende RR, Mirotti L et al. Role of m2 muscarinic receptor in the airway response to methacholine of mice selected for minimal or maximal acute inflammatory response. Biomed Res Int 2013;2013:805627.
    • (2013) Biomed Res Int , vol.2013 , pp. 805627
    • Castro, J.M.1    Resende, R.R.2    Mirotti, L.3
  • 44
    • 0033534192 scopus 로고    scopus 로고
    • Role of M2 muscarinic receptors in airway smooth muscle contraction
    • Hirshman CA, Lande B, Croxton TL. Role of M2 muscarinic receptors in airway smooth muscle contraction. Life Sci 1999;64:443-448.
    • (1999) Life Sci , vol.64 , pp. 443-448
    • Hirshman, C.A.1    Lande, B.2    Croxton, T.L.3
  • 45
    • 0029266360 scopus 로고
    • Pretreatment with an antibody to interleukin-5 prevents loss of pulmonary M2 muscarinic receptor function in antigen-challenged guinea pigs
    • Elbon CL, Jacoby DB, Fryer AD. Pretreatment with an antibody to interleukin-5 prevents loss of pulmonary M2 muscarinic receptor function in antigen-challenged guinea pigs. Am J Respir Cell Mol Biol 1995;12:320-328.
    • (1995) Am J Respir Cell Mol Biol , vol.12 , pp. 320-328
    • Elbon, C.L.1    Jacoby, D.B.2    Fryer, A.D.3
  • 46
    • 0027232088 scopus 로고
    • Human eosinophil major basic protein is an endogenous allosteric antagonist at the inhibitory muscarinic M2 receptor
    • Jacoby DB, Gleich GJ, Fryer AD. Human eosinophil major basic protein is an endogenous allosteric antagonist at the inhibitory muscarinic M2 receptor. J Clin Invest 1993;91:1314-1318.
    • (1993) J Clin Invest , vol.91 , pp. 1314-1318
    • Jacoby, D.B.1    Gleich, G.J.2    Fryer, A.D.3
  • 47
    • 84911896174 scopus 로고    scopus 로고
    • Stem cells in animal asthma models: A systematic review
    • Srour N, Thebaud B. Stem cells in animal asthma models: A systematic review. Cytotherapy 2014;16:1629-1642.
    • (2014) Cytotherapy , vol.16 , pp. 1629-1642
    • Srour, N.1    Thebaud, B.2
  • 48
    • 84908132425 scopus 로고    scopus 로고
    • Plasticity of mesenchymal stem cells in immunomodulation: Pathological and therapeutic implications
    • Wang Y, Chen X, Cao W et al. Plasticity of mesenchymal stem cells in immunomodulation: Pathological and therapeutic implications. Nat Immunol 2014;15:1009-1016.
    • (2014) Nat Immunol , vol.15 , pp. 1009-1016
    • Wang, Y.1    Chen, X.2    Cao, W.3


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