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Volumn , Issue , 2016, Pages 254-264

Functional role of striatal A2A, D2, and mGlu5 receptor interactions in regulating striatopallidal GABA neuronal transmission

Author keywords

CGS21680; CHPG; extracellular GABA and glutamate levels; Parkinson's disease; quinpirole; receptor heteromers

Indexed keywords

2 CHLORO 5 HYDROXYPHENYLGLYCINE; 2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; 2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 4 AMINOBUTYRIC ACID; 4 [2 [7 AMINO 2 (2 FURYL) 1,2,4 TRIAZOLO[2,3 A][1,3,5]TRIAZIN 5 YLAMINO]ETHYL]PHENOL; ADENOSINE A2A RECEPTOR; DOPAMINE 2 RECEPTOR; GLUTAMIC ACID; METABOTROPIC RECEPTOR 5; QUINPIROLE;

EID: 84979010983     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.13652     Document Type: Article
Times cited : (39)

References (41)
  • 1
    • 0042467972 scopus 로고    scopus 로고
    • Molecular mechanisms and therapeutical implications of intramembrane receptor/receptor interactions among heptahelical receptors with examples from the striatopallidal GABA neurons
    • and
    • Agnati L. F., Ferre S., Lluis C., Franco R. and Fuxe K. (2003) Molecular mechanisms and therapeutical implications of intramembrane receptor/receptor interactions among heptahelical receptors with examples from the striatopallidal GABA neurons. Pharmacol. Rev. 55, 509–550.
    • (2003) Pharmacol. Rev. , vol.55 , pp. 509-550
    • Agnati, L.F.1    Ferre, S.2    Lluis, C.3    Franco, R.4    Fuxe, K.5
  • 2
    • 0028175521 scopus 로고
    • The development of D2 autoreceptor-mediated modulation of K(+)-evoked dopamine release in the neostriatum
    • and
    • Andersen S. L. and Gazzara R. A. (1994) The development of D2 autoreceptor-mediated modulation of K(+)-evoked dopamine release in the neostriatum. Brain Res. Dev. Brain Res. 78, 123–130.
    • (1994) Brain Res. Dev. Brain Res. , vol.78 , pp. 123-130
    • Andersen, S.L.1    Gazzara, R.A.2
  • 3
    • 80055002811 scopus 로고    scopus 로고
    • Past, present and future of A(2A) adenosine receptor antagonists in the therapy of Parkinson's disease
    • and
    • Armentero M. T., Pinna A., Ferré S., Lanciego J. L., Müller C. E. and Franco R. (2011) Past, present and future of A(2A) adenosine receptor antagonists in the therapy of Parkinson's disease. Pharmacol. Ther. 132, 280–299.
    • (2011) Pharmacol. Ther. , vol.132 , pp. 280-299
    • Armentero, M.T.1    Pinna, A.2    Ferré, S.3    Lanciego, J.L.4    Müller, C.E.5    Franco, R.6
  • 4
    • 84882859493 scopus 로고    scopus 로고
    • GET73 increases rat extracellular hippocampal CA1 GABA levels through a possible involvement of local mGlu5 receptor
    • and
    • Beggiato S., O'Connor W. T., Tomasini M. C., Antonelli T., Loche A., Tanganelli S., Cacciaglia R. and Ferraro L. (2013a) GET73 increases rat extracellular hippocampal CA1 GABA levels through a possible involvement of local mGlu5 receptor. Synapse 67, 678–691.
    • (2013) Synapse , vol.67 , pp. 678-691
    • Beggiato, S.1    O'Connor, W.T.2    Tomasini, M.C.3    Antonelli, T.4    Loche, A.5    Tanganelli, S.6    Cacciaglia, R.7    Ferraro, L.8
  • 5
    • 84877586530 scopus 로고    scopus 로고
    • Kynurenic acid, by targeting α7 nicotinic acetylcholine receptors, modulates extracellular GABA levels in the rat striatum in vivo
    • and
    • Beggiato S., Antonelli T., Tomasini M. C., Tanganelli S., Fuxe K., Schwarcz R. and Ferraro L. (2013b) Kynurenic acid, by targeting α7 nicotinic acetylcholine receptors, modulates extracellular GABA levels in the rat striatum in vivo. Eur. J. Neurosci. 37, 1470–1477.
    • (2013) Eur. J. Neurosci. , vol.37 , pp. 1470-1477
    • Beggiato, S.1    Antonelli, T.2    Tomasini, M.C.3    Tanganelli, S.4    Fuxe, K.5    Schwarcz, R.6    Ferraro, L.7
  • 6
    • 79959612579 scopus 로고    scopus 로고
    • Moonlighting characteristics of G protein-coupled receptors: focus on receptor heteromers and relevance for neurodegeneration
    • and
    • Borroto-Escuela D. O., Tarakanov A. O., Guidolin D., Ciruela F., Agnati L. F. and Fuxe K. (2011) Moonlighting characteristics of G protein-coupled receptors: focus on receptor heteromers and relevance for neurodegeneration. IUBMB Life 63, 463–472.
    • (2011) IUBMB Life , vol.63 , pp. 463-472
    • Borroto-Escuela, D.O.1    Tarakanov, A.O.2    Guidolin, D.3    Ciruela, F.4    Agnati, L.F.5    Fuxe, K.6
  • 8
    • 84865739743 scopus 로고    scopus 로고
    • Transcriptional profiling of striatal neurons in response to single or concurrent activation of dopamine D2, adenosine A(2A) and metabotropic glutamate type 5 receptors: focus on beta-synuclein expression
    • Canela L., Selga E., García-Martínez J. M. et al. (2012) Transcriptional profiling of striatal neurons in response to single or concurrent activation of dopamine D2, adenosine A(2A) and metabotropic glutamate type 5 receptors: focus on beta-synuclein expression. Gene 508, 199–205.
    • (2012) Gene , vol.508 , pp. 199-205
    • Canela, L.1    Selga, E.2    García-Martínez, J.M.3
  • 10
    • 33644789510 scopus 로고    scopus 로고
    • Dialysis delivery of an adenosine A2A agonist into the pontine reticular formation of C57BL/6J mouse increases pontine acetylcholine release and sleep
    • and
    • Coleman C. G., Baghdoyan H. A. and Lydic R. (2006) Dialysis delivery of an adenosine A2A agonist into the pontine reticular formation of C57BL/6J mouse increases pontine acetylcholine release and sleep. J. Neurochem. 96, 1750–1759.
    • (2006) J. Neurochem. , vol.96 , pp. 1750-1759
    • Coleman, C.G.1    Baghdoyan, H.A.2    Lydic, R.3
  • 11
    • 0037123728 scopus 로고    scopus 로고
    • Metabotropic glutamate mGlu5 receptor-mediated modulation of the ventral striopallidal GABA pathway in rats. Interactions with adenosine A(2A) and dopamine D(2) receptors
    • and
    • Díaz-Cabiale Z., Vivó M., Del Arco A., O'Connor W. T., Harte M. K., Müller C. E., Martínez E., Popoli P., Fuxe K. and Ferré S. (2002) Metabotropic glutamate mGlu5 receptor-mediated modulation of the ventral striopallidal GABA pathway in rats. Interactions with adenosine A(2A) and dopamine D(2) receptors. Neurosci. Lett. 324, 154–158.
    • (2002) Neurosci. Lett. , vol.324 , pp. 154-158
    • Díaz-Cabiale, Z.1    Vivó, M.2    Del Arco, A.3    O'Connor, W.T.4    Harte, M.K.5    Müller, C.E.6    Martínez, E.7    Popoli, P.8    Fuxe, K.9    Ferré, S.10
  • 12
    • 0030894148 scopus 로고    scopus 로고
    • (RS)-2-chloro-5-hydroxyphenylglycine (CHPG) activates mGlu5, but no mGlu1, receptors expressed in CHO cells and potentiates NMDA responses in the hippocampus
    • and
    • Doherty A. J., Palmer M. J., Henley J. M., Collingridge G. L. and Jane D. E. (1997) (RS)-2-chloro-5-hydroxyphenylglycine (CHPG) activates mGlu5, but no mGlu1, receptors expressed in CHO cells and potentiates NMDA responses in the hippocampus. Neuropharmacology 36, 265–267.
    • (1997) Neuropharmacology , vol.36 , pp. 265-267
    • Doherty, A.J.1    Palmer, M.J.2    Henley, J.M.3    Collingridge, G.L.4    Jane, D.E.5
  • 13
    • 0038555125 scopus 로고    scopus 로고
    • Characterisation of the actions of group I metabotropic glutamate receptor subtype selective ligands on excitatory amino acid release and sodium-dependent re-uptake in rat cerebrocortical minislices
    • and
    • Fazal A., Parker F., Palmer A. M. and Croucher M. J. (2003) Characterisation of the actions of group I metabotropic glutamate receptor subtype selective ligands on excitatory amino acid release and sodium-dependent re-uptake in rat cerebrocortical minislices. J. Neurochem. 86, 1346–1358.
    • (2003) J. Neurochem. , vol.86 , pp. 1346-1358
    • Fazal, A.1    Parker, F.2    Palmer, A.M.3    Croucher, M.J.4
  • 14
    • 0032171364 scopus 로고    scopus 로고
    • The striatal neurotensin receptor modulates striatal and pallidal glutamate and GABA release: functional evidence for a pallidal glutamate-GABA interaction via the pallidal-subthalamic nucleus loop
    • and
    • Ferraro L., Antonelli T., O'Connor W. T., Fuxe K., Soubrié P. and Tanganelli S. (1998) The striatal neurotensin receptor modulates striatal and pallidal glutamate and GABA release: functional evidence for a pallidal glutamate-GABA interaction via the pallidal-subthalamic nucleus loop. J. Neurosci. 18, 6977–6989.
    • (1998) J. Neurosci. , vol.18 , pp. 6977-6989
    • Ferraro, L.1    Antonelli, T.2    O'Connor, W.T.3    Fuxe, K.4    Soubrié, P.5    Tanganelli, S.6
  • 15
    • 84866863955 scopus 로고    scopus 로고
    • A(2A)/D(2) receptor heteromerization in a model of Parkinson's disease. Focus on striatal aminoacidergic signaling
    • and
    • Ferraro L., Beggiato S., Tomasini M. C., Fuxe K., Antonelli T. and Tanganelli S. (2012a) A(2A)/D(2) receptor heteromerization in a model of Parkinson's disease. Focus on striatal aminoacidergic signaling. Brain Res. 1476, 96–107.
    • (2012) Brain Res. , vol.1476 , pp. 96-107
    • Ferraro, L.1    Beggiato, S.2    Tomasini, M.C.3    Fuxe, K.4    Antonelli, T.5    Tanganelli, S.6
  • 16
    • 84855923294 scopus 로고    scopus 로고
    • Striatal NTS1, dopamine D2 and NMDA receptor regulation of pallidal GABA and glutamate release–a dual-probe microdialysis study in the intranigral 6-hydroxydopamine unilaterally lesioned rat
    • and
    • Ferraro L., O'Connor W. T., Beggiato S., Tomasini M. C., Fuxe K., Tanganelli S. and Antonelli T. (2012b) Striatal NTS1, dopamine D2 and NMDA receptor regulation of pallidal GABA and glutamate release–a dual-probe microdialysis study in the intranigral 6-hydroxydopamine unilaterally lesioned rat. Eur. J. Neurosci. 35, 207–220.
    • (2012) Eur. J. Neurosci. , vol.35 , pp. 207-220
    • Ferraro, L.1    O'Connor, W.T.2    Beggiato, S.3    Tomasini, M.C.4    Fuxe, K.5    Tanganelli, S.6    Antonelli, T.7
  • 17
    • 0027140986 scopus 로고
    • The striopallidal neuron: a main locus for adenosine-dopamine interactions in the brain
    • and
    • Ferré S., O'Connor W. T., Fuxe K. and Ungerstedt U. (1993) The striopallidal neuron: a main locus for adenosine-dopamine interactions in the brain. J. Neurosci. 13, 5402–5406.
    • (1993) J. Neurosci. , vol.13 , pp. 5402-5406
    • Ferré, S.1    O'Connor, W.T.2    Fuxe, K.3    Ungerstedt, U.4
  • 18
    • 0032587703 scopus 로고    scopus 로고
    • Adenosine A2A and group I metabotropic glutamate receptors synergistically modulate the binding characteristics of dopamine D2 receptors in the rat striatum
    • and
    • Ferre′ S., Popoli P., Rimondini R., Reggio R., Kehr J. and Fuxe K. (1999) Adenosine A2A and group I metabotropic glutamate receptors synergistically modulate the binding characteristics of dopamine D2 receptors in the rat striatum. Neuropharmacology 38, 129–140.
    • (1999) Neuropharmacology , vol.38 , pp. 129-140
    • Ferre′, S.1    Popoli, P.2    Rimondini, R.3    Reggio, R.4    Kehr, J.5    Fuxe, K.6
  • 19
    • 10744224952 scopus 로고    scopus 로고
    • Receptor heteromerization in adenosine A2A receptor signaling: relevance for striatal function and Parkinson's disease
    • Fuxe K., Agnati L. F., Jacobsen K. et al. (2003) Receptor heteromerization in adenosine A2A receptor signaling: relevance for striatal function and Parkinson's disease. Neurology 61, S19–S23.
    • (2003) Neurology , vol.61 , pp. S19-S23
    • Fuxe, K.1    Agnati, L.F.2    Jacobsen, K.3
  • 20
    • 25844477182 scopus 로고    scopus 로고
    • Adenosine A2A and dopamine D2 heteromeric receptor complexes and their function
    • Fuxe K., Ferré S., Canals M. et al. (2005) Adenosine A2A and dopamine D2 heteromeric receptor complexes and their function. J. Mol. Neurosci. 26, 209–220.
    • (2005) J. Mol. Neurosci. , vol.26 , pp. 209-220
    • Fuxe, K.1    Ferré, S.2    Canals, M.3
  • 21
    • 33845911715 scopus 로고    scopus 로고
    • Intramembrane receptor-receptor interactions: a novel principle in molecular medicine
    • Fuxe K., Canals M., Torvinen M. et al. (2007) Intramembrane receptor-receptor interactions: a novel principle in molecular medicine. J. Neural. Transm. 114, 49–75.
    • (2007) J. Neural. Transm. , vol.114 , pp. 49-75
    • Fuxe, K.1    Canals, M.2    Torvinen, M.3
  • 22
    • 72449203291 scopus 로고    scopus 로고
    • Molecular integration via allosteric interactions in receptor heteromers. A working hypothesis
    • and
    • Fuxe K., Marcellino D., Leo G. and Agnati L. F. (2010) Molecular integration via allosteric interactions in receptor heteromers. A working hypothesis. Curr. Opin. Pharmacol. 10, 14–22.
    • (2010) Curr. Opin. Pharmacol. , vol.10 , pp. 14-22
    • Fuxe, K.1    Marcellino, D.2    Leo, G.3    Agnati, L.F.4
  • 24
    • 84923069906 scopus 로고    scopus 로고
    • Dopamine heteroreceptor complexes as therapeutic targets in Parkinson's disease
    • and
    • Fuxe K., Guidolin D., Agnati L. F. and Borroto-Escuela D. O. (2015) Dopamine heteroreceptor complexes as therapeutic targets in Parkinson's disease. Expert Opin. Ther. Targets 19, 377–398.
    • (2015) Expert Opin. Ther. Targets , vol.19 , pp. 377-398
    • Fuxe, K.1    Guidolin, D.2    Agnati, L.F.3    Borroto-Escuela, D.O.4
  • 25
    • 0035848459 scopus 로고    scopus 로고
    • Ultrastructural localization of adenosine A2A receptors suggests multiple cellular sites for modulation of GABAergic neurons in rat striatum
    • and
    • Hettinger B. D., Lee A., Linden J. and Rosin D. L. (2001) Ultrastructural localization of adenosine A2A receptors suggests multiple cellular sites for modulation of GABAergic neurons in rat striatum. J. Comp. Neurol. 431, 331–346.
    • (2001) J. Comp. Neurol. , vol.431 , pp. 331-346
    • Hettinger, B.D.1    Lee, A.2    Linden, J.3    Rosin, D.L.4
  • 26
    • 27744450594 scopus 로고    scopus 로고
    • Interactions between metabotropic glutamate 5 and adenosine A2A receptors in normal and parkinsonian mice
    • and
    • Kachroo A., Orlando L. R., Grandy D. K., Chen J. F., Young A. B. and Schwarzschild M. A. (2005) Interactions between metabotropic glutamate 5 and adenosine A2A receptors in normal and parkinsonian mice. J. Neurosci. 25, 10414–10419.
    • (2005) J. Neurosci. , vol.25 , pp. 10414-10419
    • Kachroo, A.1    Orlando, L.R.2    Grandy, D.K.3    Chen, J.F.4    Young, A.B.5    Schwarzschild, M.A.6
  • 27
    • 84906727634 scopus 로고    scopus 로고
    • Interaction of adenosine receptors with other receptors from therapeutic perspective in Parkinson's disease
    • and
    • Morin N. and Di Paolo T. (2014) Interaction of adenosine receptors with other receptors from therapeutic perspective in Parkinson's disease. Int. Rev. Neurobiol. 119, 151–167.
    • (2014) Int. Rev. Neurobiol. , vol.119 , pp. 151-167
    • Morin, N.1    Di Paolo, T.2
  • 28
    • 84975775480 scopus 로고    scopus 로고
    • mGlu5, Dopamine D2 and Adenosine A2A Receptors in L-DOPA-Induced Dyskinesias
    • and
    • Morin N., Morissette M., Grégoire L. and Di Paolo T. (2015) mGlu5, Dopamine D2 and Adenosine A2A Receptors in L-DOPA-Induced Dyskinesias. Curr. Neuropharmacol. DOI 10.2174/1570159X14666151201185652
    • (2015) Curr. Neuropharmacol.
    • Morin, N.1    Morissette, M.2    Grégoire, L.3    Di Paolo, T.4
  • 30
    • 0042422052 scopus 로고    scopus 로고
    • Group I metabotropic glutamate receptors in the monkey striatum: subsynaptic association with glutamatergic and dopaminergic afferents
    • and
    • Paquet M. and Smith Y. (2013) Group I metabotropic glutamate receptors in the monkey striatum: subsynaptic association with glutamatergic and dopaminergic afferents. J. Neurosci. 23, 7659–7669.
    • (2013) J. Neurosci. , vol.23 , pp. 7659-7669
    • Paquet, M.1    Smith, Y.2
  • 32
    • 0034626632 scopus 로고    scopus 로고
    • The mGlu5 receptor agonist CHPG stimulates striatal glutamate release: possible involvement of A2A receptors
    • and
    • Pintor A., Pèzzola A., Reggio R., Quarta D. and Popoli P. (2000) The mGlu5 receptor agonist CHPG stimulates striatal glutamate release: possible involvement of A2A receptors. NeuroReport 11, 3611–3614.
    • (2000) NeuroReport , vol.11 , pp. 3611-3614
    • Pintor, A.1    Pèzzola, A.2    Reggio, R.3    Quarta, D.4    Popoli, P.5
  • 33
    • 0034856088 scopus 로고    scopus 로고
    • The selective mGlu(5) receptor agonist CHPG inhibits quinpirole-induced turning in 6-hydroxydopamine-lesioned rats and modulates the binding characteristics of dopamine D(2) receptors in the rat striatum: interactions with adenosine A(2a) receptors
    • and
    • Popoli P., Pèzzola A., Torvinen M., Reggio R., Pintor A., Scarchilli L., Fuxe K. and Ferré S. (2001) The selective mGlu(5) receptor agonist CHPG inhibits quinpirole-induced turning in 6-hydroxydopamine-lesioned rats and modulates the binding characteristics of dopamine D(2) receptors in the rat striatum: interactions with adenosine A(2a) receptors. Neuropsychopharmacology 25, 505–513.
    • (2001) Neuropsychopharmacology , vol.25 , pp. 505-513
    • Popoli, P.1    Pèzzola, A.2    Torvinen, M.3    Reggio, R.4    Pintor, A.5    Scarchilli, L.6    Fuxe, K.7    Ferré, S.8
  • 34
    • 0025362908 scopus 로고
    • The effects of intranigral GABA and dynorphin A injections on striatal dopamine and GABA release: evidence that dopamine provides inhibitory regulation of striatal GABA neurons via D2 receptors
    • and
    • Reid M. S., O'Connor W. T., Herrera-Marschitz M. and Ungerstedt U. (1990) The effects of intranigral GABA and dynorphin A injections on striatal dopamine and GABA release: evidence that dopamine provides inhibitory regulation of striatal GABA neurons via D2 receptors. Brain Res. 519, 255–260.
    • (1990) Brain Res. , vol.519 , pp. 255-260
    • Reid, M.S.1    O'Connor, W.T.2    Herrera-Marschitz, M.3    Ungerstedt, U.4
  • 35
    • 0033551584 scopus 로고    scopus 로고
    • Multiple intramembrane receptor-receptor interactions in the regulation of striatal dopamine D2 receptors
    • and
    • Rimondini R., Fuxe K. and Ferré S. (1999) Multiple intramembrane receptor-receptor interactions in the regulation of striatal dopamine D2 receptors. NeuroReport 10, 2051–2054.
    • (1999) NeuroReport , vol.10 , pp. 2051-2054
    • Rimondini, R.1    Fuxe, K.2    Ferré, S.3
  • 38
    • 47349112609 scopus 로고    scopus 로고
    • Adenosine A2A receptor antagonists and Parkinson's disease: state of the art and future directions
    • and
    • Simola N., Morelli M. and Pinna A. (2008) Adenosine A2A receptor antagonists and Parkinson's disease: state of the art and future directions. Curr. Pharm. Des. 14, 1475–1489.
    • (2008) Curr. Pharm. Des. , vol.14 , pp. 1475-1489
    • Simola, N.1    Morelli, M.2    Pinna, A.3
  • 39
    • 0028037239 scopus 로고
    • A role for non-NMDA excitatory amino acid receptors in regulating the basal activity of rat globus pallidus neurons and their activation by the subthalamic nucleus
    • and
    • Soltis R. P., Anderson L. A., Walters J. R. and Kelland M. D. (1994) A role for non-NMDA excitatory amino acid receptors in regulating the basal activity of rat globus pallidus neurons and their activation by the subthalamic nucleus. Brain Res. 666, 21–30.
    • (1994) Brain Res. , vol.666 , pp. 21-30
    • Soltis, R.P.1    Anderson, L.A.2    Walters, J.R.3    Kelland, M.D.4
  • 41
    • 0028987178 scopus 로고
    • Immunocytochemical localization of D1 and D2 dopamine receptors in the basal ganglia of the rat: light and electron microscopy
    • and
    • Yung K. K., Bolam J. P., Smith A. D., Hersch S. M., Ciliax B. J. and Levey A. I. (1995) Immunocytochemical localization of D1 and D2 dopamine receptors in the basal ganglia of the rat: light and electron microscopy. Neuroscience 65, 709–730.
    • (1995) Neuroscience , vol.65 , pp. 709-730
    • Yung, K.K.1    Bolam, J.P.2    Smith, A.D.3    Hersch, S.M.4    Ciliax, B.J.5    Levey, A.I.6


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