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Volumn 63, Issue 7, 2011, Pages 463-472

Moonlighting characteristics of G protein-coupled receptors: Focus on receptor heteromers and relevance for neurodegeneration

Author keywords

G protein coupled receptors; heterodimers; moonlighting protein; receptor tyrosine kinase

Indexed keywords

ALANYLALANYLARGINYL; ALANYLALANYLGLUTAMYL; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMINO ACID; ARGINYLALANYLALANYL; BETA ARRESTIN; CALMODULIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; EPITOPE; FIBROBLAST GROWTH FACTOR RECEPTOR 1; G PROTEIN COUPLED RECEPTOR; GLUTAMYLALANYLALANYL; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; MOONLIGHTING PROTEIN; N METHYL DEXTRO ASPARTIC ACID; PROTEIN; PROTEIN TYROSINE KINASE; RAF PROTEIN; RAS PROTEIN; SERYLALANYLGLUTAMINYLGLUTAMYLPROLYLSERYLGLUTAMINYLGLYCYLASPARAGINYLTHREONYL; STAT PROTEIN; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG; VALYLLEUCYLARGINYLARGINYLARGINYLARGINYLLYSYLARGINYLVALYLASPARAGINYL;

EID: 79959612579     PISSN: 15216543     EISSN: 15216551     Source Type: Journal    
DOI: 10.1002/iub.473     Document Type: Review
Times cited : (54)

References (64)
  • 1
    • 0024520027 scopus 로고
    • Enzyme/crystallins: Gene sharing as an evolutionary strategy
    • DOI 10.1016/0092-8674(89)90956-2
    • Piatigorsky, J., and, Wistow, G. J., (1989) Enzyme/crystallins: gene sharing as an evolutionary strategy. Cell 57, 197-199. (Pubitemid 19112359)
    • (1989) Cell , vol.57 , Issue.2 , pp. 197-199
    • Piatigorsky, J.1    Wistow, G.J.2
  • 2
    • 0037235543 scopus 로고    scopus 로고
    • Multifunctional proteins: Examples of gene sharing
    • DOI 10.1080/07853890310004101
    • Jeffery, C. J., (2003) Multifunctional proteins: examples of gene sharing. Ann. Med. 35, 28-35. (Pubitemid 36356871)
    • (2003) Annals of Medicine , vol.35 , Issue.1 , pp. 28-35
    • Jeffery, C.J.1
  • 3
    • 62949096122 scopus 로고    scopus 로고
    • Moonlighting proteins-an update
    • Jeffery, C. J., (2009) Moonlighting proteins-an update. Mol. Biosyst. 5, 345-350.
    • (2009) Mol. Biosyst. , vol.5 , pp. 345-350
    • Jeffery, C.J.1
  • 4
    • 77950369259 scopus 로고    scopus 로고
    • Moonlighting proteins: An intriguing mode of multitasking
    • Huberts, D. H., and, van der Klei, I. J., Moonlighting proteins: an intriguing mode of multitasking. Biochim. Biophys. Acta 1803, 520-525.
    • Biochim. Biophys. Acta , vol.1803 , pp. 520-525
    • Huberts, D.H.1    Van Der Klei, I.J.2
  • 5
    • 0042706146 scopus 로고    scopus 로고
    • Moonlighting proteins: Old proteins learning new tricks
    • DOI 10.1016/S0168-9525(03)00167-7
    • Jeffery, C. J., (2003) Moonlighting proteins: old proteins learning new tricks. Trends Genet. 19, 415-417. (Pubitemid 36930022)
    • (2003) Trends in Genetics , vol.19 , Issue.8 , pp. 415-417
    • Jeffery, C.J.1
  • 7
    • 23844452781 scopus 로고    scopus 로고
    • New nuclear functions of the glycolytic protein, glyceraldehyde-3- phosphate dehydrogenase, in mammalian cells
    • DOI 10.1002/jcb.20399
    • Sirover, M. A., (2005) New nuclear functions of the glycolytic protein, glyceraldehyde-3-phosphate dehydrogenase, in mammalian cells. J. Cell. Biochem. 95, 45-52. (Pubitemid 41420214)
    • (2005) Journal of Cellular Biochemistry , vol.95 , Issue.1 , pp. 45-52
    • Sirover, M.A.1
  • 9
    • 77954242320 scopus 로고    scopus 로고
    • Nuclear transport receptor goes moonlighting
    • Gruss, O. J., (2010) Nuclear transport receptor goes moonlighting. Nat. Cell. Biol. 12, 640-641.
    • (2010) Nat. Cell. Biol. , vol.12 , pp. 640-641
    • Gruss, O.J.1
  • 11
  • 12
    • 0017771466 scopus 로고
    • Evolution and tinkering
    • Jacob, F., (1977) Evolution and tinkering. Science 196, 1161-1166.
    • (1977) Science , vol.196 , pp. 1161-1166
    • Jacob, F.1
  • 13
    • 34548815693 scopus 로고    scopus 로고
    • Modular architecture of protein structures and allosteric communications: Potential implications for signaling proteins and regulatory linkages
    • Del Sol, A., Arauzo-Bravo, M. J., Amoros, D., and, Nussinov, R., (2007) Modular architecture of protein structures and allosteric communications: potential implications for signaling proteins and regulatory linkages. Genome Biol. 8, R92.
    • (2007) Genome Biol. , vol.8
    • Del Sol, A.1    Arauzo-Bravo, M.J.2    Amoros, D.3    Nussinov, R.4
  • 15
    • 36448968578 scopus 로고    scopus 로고
    • Allosteric modulation of heterodimeric G-protein-coupled receptors
    • DOI 10.1016/j.tips.2007.11.001, PII S0165614707002581
    • Milligan, G., and, Smith, N. J., (2007) Allosteric modulation of heterodimeric G-protein-coupled receptors. Trends Pharmacol. Sci. 28, 615-620. (Pubitemid 350166577)
    • (2007) Trends in Pharmacological Sciences , vol.28 , Issue.12 , pp. 615-620
    • Milligan, G.1    Smith, N.J.2
  • 16
    • 25844443526 scopus 로고    scopus 로고
    • Is the GABA B heterodimer a good drug target?
    • Marshall, F. H., (2005) Is the GABA B heterodimer a good drug target? J. Mol. Neurosci. 26, 169-176.
    • (2005) J. Mol. Neurosci. , vol.26 , pp. 169-176
    • Marshall, F.H.1
  • 17
    • 35048825300 scopus 로고    scopus 로고
    • On the nested hierarchical organization of CNS: Basic characteristics of neuronal molecular networks
    • (Esposito, E. P., Marinaro, M., and Scarpetta, S., eds.). Springer, Berlin
    • Agnati, L. F., Santarossa, L., Genedani, S., Canela, E. I., Leo, G., Franco, R., Woods, A., Lluis, C., Ferré, S., and, Fuxe, K., (2004) On the nested hierarchical organization of CNS: basic characteristics of neuronal molecular networks. In Computational Neuroscienc: Cortical Dynamics (, Esposito, E. P., Marinaro, M., and, Scarpetta, S., eds.). pp. 24-54, Springer, Berlin.
    • (2004) Computational Neuroscienc: Cortical Dynamics , pp. 24-54
    • Agnati, L.F.1    Santarossa, L.2    Genedani, S.3    Canela, E.I.4    Leo, G.5    Franco, R.6    Woods, A.7    Lluis, C.8    Ferré, S.9    Fuxe, K.10
  • 20
    • 0042467972 scopus 로고    scopus 로고
    • Molecular mechanisms and therapeutical implications of intramembrane receptor/receptor interactions among heptahelical receptors with examples from the striatopallidal GABA neurons
    • DOI 10.1124/pr.55.3.2
    • Agnati, L. F., Ferre, S., Lluis, C., Franco, R., and, Fuxe, K., (2003) Molecular mechanisms and therapeutical implications of intramembrane receptor/receptor interactions among heptahelical receptors with examples from the striatopallidal GABA neurons. Pharmacol. Rev. 55, 509-550. (Pubitemid 37013214)
    • (2003) Pharmacological Reviews , vol.55 , Issue.3 , pp. 509-550
    • Agnati, L.F.1    Ferre, S.2    Lluis, C.3    Franco, R.4    Fuxe, K.5
  • 21
    • 77957076205 scopus 로고    scopus 로고
    • An integrated view on the role of receptor mosaics at perisynaptic level: Focus on adenosine A(2A), dopamine D(2), cannabinoid CB(1), and metabotropic glutamate mGlu(5) receptors
    • Agnati, L. F., Guidolin, D., Albertin, G., Trivello, E., Ciruela, F., Genedani, S., Tarakanov, A., and, Fuxe, K., (2010) An integrated view on the role of receptor mosaics at perisynaptic level: focus on adenosine A(2A), dopamine D(2), cannabinoid CB(1), and metabotropic glutamate mGlu(5) receptors. J. Recept. Signal. Transduct. Res. 30, 355-369.
    • (2010) J. Recept. Signal. Transduct. Res. , vol.30 , pp. 355-369
    • Agnati, L.F.1    Guidolin, D.2    Albertin, G.3    Trivello, E.4    Ciruela, F.5    Genedani, S.6    Tarakanov, A.7    Fuxe, K.8
  • 23
    • 0032078541 scopus 로고    scopus 로고
    • 1 receptor interactions in the basal ganglia
    • DOI 10.1016/S0165-0173(97)00049-0, PII S0165017397000490
    • Fuxe, K., Ferre, S., Zoli, M., and, Agnati, L. F., (1998) Integrated events in central dopamine transmission as analyzed at multiple levels. Evidence for intramembrane adenosine A2A/dopamine D2 and adenosine A1/dopamine D1 receptor interactions in the basal ganglia. Brain Res. Brain Res. Rev. 26, 258-273. (Pubitemid 28318081)
    • (1998) Brain Research Reviews , vol.26 , Issue.2-3 , pp. 258-273
    • Fuxe, K.1    Ferre, S.2    Zoli, M.3    Agnati, L.F.4
  • 25
    • 72449203291 scopus 로고    scopus 로고
    • Molecular integration via allosteric interactions in receptor heteromers. A working hypothesis
    • Fuxe, K., Marcellino, D., Leo, G., and, Agnati, L. F., (2010) Molecular integration via allosteric interactions in receptor heteromers. A working hypothesis. Curr. Opin. Pharmacol. 10, 14-22.
    • (2010) Curr. Opin. Pharmacol. , vol.10 , pp. 14-22
    • Fuxe, K.1    Marcellino, D.2    Leo, G.3    Agnati, L.F.4
  • 29
    • 79953196451 scopus 로고    scopus 로고
    • Bioinformatics and mathematical modelling in the study of receptor-receptor interactions and receptor oligomerization Focus on adenosine receptors
    • Guidolin, D., Ciruela, F., Genedani, S., Guescini, M., Tortorella, C., Albertin, G., Fuxe, K., and, Agnati, L. F., (2010) Bioinformatics and mathematical modelling in the study of receptor-receptor interactions and receptor oligomerization Focus on adenosine receptors. Biochim. Biophys. Acta 1808, 1267-1283.
    • (2010) Biochim. Biophys. Acta , vol.1808 , pp. 1267-1283
    • Guidolin, D.1    Ciruela, F.2    Genedani, S.3    Guescini, M.4    Tortorella, C.5    Albertin, G.6    Fuxe, K.7    Agnati, L.F.8
  • 30
    • 78649759744 scopus 로고    scopus 로고
    • G-protein-coupled receptor heteromer dynamics
    • Vilardaga, J. P., Agnati, L. F., Fuxe, K., and, Ciruela, F., (2010) G-protein-coupled receptor heteromer dynamics. J. Cell. Sci. 123, 4215-4220.
    • (2010) J. Cell. Sci. , vol.123 , pp. 4215-4220
    • Vilardaga, J.P.1    Agnati, L.F.2    Fuxe, K.3    Ciruela, F.4
  • 31
    • 49449090028 scopus 로고    scopus 로고
    • Structural plasticity in G-protein coupled receptors as demonstrated by the allosteric actions of homocysteine and computer-assisted analysis of disordered domains
    • Agnati, L. F., Leo, G., Genedani, S., Andreoli, N., Marcellino, D., Woods, A., Piron, L., Guidolin, D., and, Fuxe, K., (2008) Structural plasticity in G-protein coupled receptors as demonstrated by the allosteric actions of homocysteine and computer-assisted analysis of disordered domains. Brain. Res. Rev. 58, 459-474.
    • (2008) Brain. Res. Rev. , vol.58 , pp. 459-474
    • Agnati, L.F.1    Leo, G.2    Genedani, S.3    Andreoli, N.4    Marcellino, D.5    Woods, A.6    Piron, L.7    Guidolin, D.8    Fuxe, K.9
  • 32
    • 77951620820 scopus 로고    scopus 로고
    • Triplet puzzle: Homologies of receptor heteromers
    • Tarakanov, A. O., and, Fuxe, K. G., (2010) Triplet puzzle: homologies of receptor heteromers. J. Mol. Neurosci. 41, 294-303.
    • (2010) J. Mol. Neurosci. , vol.41 , pp. 294-303
    • Tarakanov, A.O.1    Fuxe, K.G.2
  • 34
    • 25844479865 scopus 로고    scopus 로고
    • Functions of heteromeric association between adenosine and P2Y receptors
    • DOI 10.1385/JMN:26:2-3:233
    • Nakata, H., Yoshioka, K., Kamiya, T., Tsuga, H., and, Oyanagi, K., (2005) Functions of heteromeric association between adenosine and P2Y receptors. J. Mol. Neurosci. 26, 233-238. (Pubitemid 41389415)
    • (2005) Journal of Molecular Neuroscience , vol.26 , Issue.2-3 , pp. 233-238
    • Nakata, H.1    Yoshioka, K.2    Kamiya, T.3    Tsuga, H.4    Oyanagi, K.5
  • 35
    • 35649005909 scopus 로고    scopus 로고
    • Neuronal Gq/11-coupled dopamine receptors: An uncharted role for dopamine
    • DOI 10.1016/j.tips.2007.10.001, PII S0165614707002258
    • Rashid, A. J., O'Dowd, B. F., Verma, V., and, George, S. R., (2007) Neuronal Gq/11-coupled dopamine receptors: an uncharted role for dopamine. Trends Pharmacol. Sci. 28, 551-555. (Pubitemid 350026611)
    • (2007) Trends in Pharmacological Sciences , vol.28 , Issue.11 , pp. 551-555
    • Rashid, A.J.1    O'Dowd, B.F.2    Verma, V.3    George, S.R.4
  • 36
    • 0034688225 scopus 로고    scopus 로고
    • Direct protein-protein coupling enables cross-talk between dopamine D5 and γ-aminobutyric acid A receptors
    • DOI 10.1038/35002014
    • Liu, F., Wan, Q., Pristupa, Z. B., Yu, X. M., Wang, Y. T., and, Niznik, H. B., (2000) Direct protein-protein coupling enables cross-talk between dopamine D5 and gamma-aminobutyric acid A receptors. Nature 403, 274-280. (Pubitemid 30062376)
    • (2000) Nature , vol.403 , Issue.6767 , pp. 274-280
    • Liu, F.1    Wan, Q.2    Pristupa, Z.B.3    Yu, X.-M.4    Wang, Y.T.5    Niznik, H.B.6
  • 39
    • 18844449351 scopus 로고    scopus 로고
    • Dopamine D2 receptor stimulation of mitogen-activated protein kinases mediated by cell type-dependent transactivation of receptor tyrosine kinases
    • DOI 10.1111/j.1471-4159.2005.03055.x
    • Wang, C., Buck, D. C., Yang, R., Macey, T. A., and, Neve, K. A., (2005) Dopamine D2 receptor stimulation of mitogen-activated protein kinases mediated by cell type-dependent transactivation of receptor tyrosine kinases. J. Neurochem. 93, 899-909. (Pubitemid 40695749)
    • (2005) Journal of Neurochemistry , vol.93 , Issue.4 , pp. 899-909
    • Wang, C.1    Buck, D.C.2    Yang, R.3    Macey, T.A.4    Neve, K.A.5
  • 40
    • 65949097958 scopus 로고    scopus 로고
    • The role of intrinsically unstructured proteins in neurodegenerative diseases
    • Raychaudhuri, S., Dey, S., Bhattacharyya, N. P., and, Mukhopadhyay, D., (2009) The role of intrinsically unstructured proteins in neurodegenerative diseases. PLoS One 4, e5566.
    • (2009) PLoS One , vol.4
    • Raychaudhuri, S.1    Dey, S.2    Bhattacharyya, N.P.3    Mukhopadhyay, D.4
  • 41
    • 3543083733 scopus 로고    scopus 로고
    • Dopamine D1 and D2 receptor co-activation generates a novel phospholipase C-mediated calcium signal
    • DOI 10.1074/jbc.M401923200
    • Lee, S. P., So, C. H., Rashid, A. J., Varghese, G., Cheng, R., Lanca, A. J., O'Dowd, B. F., and, George, S. R., (2004) Dopamine D1 and D2 receptor Co-activation generates a novel phospholipase C-mediated calcium signal. J. Biol. Chem. 279, 35671-35678. (Pubitemid 39100570)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.34 , pp. 35671-35678
    • Lee, S.P.1    So, C.H.2    Rashid, A.J.3    Varghese, G.4    Cheng, R.5    Lanca, A.J.6    O'Dowd, B.F.7    George, S.R.8
  • 44
    • 79951771675 scopus 로고    scopus 로고
    • On the existence of a possible A(2A)-D(2)-beta-Arrestin2 complex: A(2A) agonist modulation of D(2) agonist-induced beta-Arrestin2 recruitment
    • Borroto-Escuela, D. O., Romero-Fernandez, W., Tarakanov, A. O., Ciruela, F., Agnati, L. F., and, Fuxe, K., (2011) On the existence of a possible A(2A)-D(2)-beta-Arrestin2 complex: A(2A) agonist modulation of D(2) agonist-induced beta-Arrestin2 recruitment. J. Mol. Biol. 406, 687-699.
    • (2011) J. Mol. Biol , vol.406 , pp. 687-699
    • Borroto-Escuela, D.O.1    Romero-Fernandez, W.2    Tarakanov, A.O.3    Ciruela, F.4    Agnati, L.F.5    Fuxe, K.6
  • 49
    • 0034737483 scopus 로고    scopus 로고
    • 2-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor
    • DOI 10.1074/jbc.275.13.9572
    • Maudsley, S., Pierce, K. L., Zamah, A. M., Miller, W. E., Ahn, S., Daaka, Y., Lefkowitz, R. J., and, Luttrell, L. M., (2000) The beta(2)-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor. J. Biol. Chem. 275, 9572-9580. (Pubitemid 30185188)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.13 , pp. 9572-9580
    • Maudsley, S.1    Pierce, K.L.2    Zamah, A.M.3    Miller, W.E.4    Ahn, S.5    Daaka, Y.6    Lefkowitz, R.J.7    Luttrell, L.M.8
  • 50
    • 0043172403 scopus 로고    scopus 로고
    • Transactivation joins multiple tracks to the ERK/MAPK cascade
    • DOI 10.1038/nrm1173
    • Wetzker, R., and, Bohmer, F. D., (2003) Transactivation joins multiple tracks to the ERK/MAPK cascade. Nat. Rev. Mol. Cell. Biol. 4, 651-657. (Pubitemid 36934967)
    • (2003) Nature Reviews Molecular Cell Biology , vol.4 , Issue.8 , pp. 651-657
    • Wetzker, R.1    Bohmer, F.-D.2
  • 52
    • 84946707736 scopus 로고    scopus 로고
    • Dopamine receptors and the treatment of schizophrenia
    • Neve, K. A., ed.). Humana Press, Portland
    • Ginovart, N., and, Kapur, S., (2010) Dopamine receptors and the treatment of schizophrenia. In The Dopamine Receptor (, Neve, K. A., ed.). pp. 431-478, Humana Press, Portland.
    • (2010) The Dopamine Receptor , pp. 431-478
    • Ginovart, N.1    Kapur, S.2
  • 53
    • 33846903377 scopus 로고    scopus 로고
    • Role of neurotrophic factors in depression
    • DOI 10.1016/j.coph.2006.08.009, PII S1471489206001718, Neurosciences
    • Castren, E., Voikar, V., and, Rantamaki, T., (2007) Role of neurotrophic factors in depression. Curr. Opin. Pharmacol. 7, 18-21. (Pubitemid 46238033)
    • (2007) Current Opinion in Pharmacology , vol.7 , Issue.1 , pp. 18-21
    • Castren, E.1    Voikar, V.2    Rantamaki, T.3
  • 54
    • 34548395111 scopus 로고    scopus 로고
    • The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive-like behavior
    • DOI 10.1097/FBP.0b013e3282ee2aa8, PII 0000887720070900000008
    • Schmidt, H. D., and, Duman, R. S., (2007) The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive-like behavior. Behav. Pharmacol. 18, 391-418. (Pubitemid 47356367)
    • (2007) Behavioural Pharmacology , vol.18 , Issue.5-6 , pp. 391-418
    • Schmidt, H.D.1    Duman, R.S.2
  • 55
    • 77958021917 scopus 로고    scopus 로고
    • Peripheral BDNF produces antidepressant-like effects in cellular and behavioral models
    • Schmidt, H. D., and, Duman, R. S., (2010) Peripheral BDNF produces antidepressant-like effects in cellular and behavioral models. Neuropsychopharmacology 35, 2378-2391.
    • (2010) Neuropsychopharmacology , vol.35 , pp. 2378-2391
    • Schmidt, H.D.1    Duman, R.S.2
  • 56
    • 78149339312 scopus 로고    scopus 로고
    • N-methyl- D -aspartate glutamate receptor antagonists and the promise of rapid-acting antidepressants
    • Krystal, J. H., (2010) N-methyl- D -aspartate glutamate receptor antagonists and the promise of rapid-acting antidepressants. Arch. Gen. Psychiatry. 67, 1110-1111.
    • (2010) Arch. Gen. Psychiatry. , vol.67 , pp. 1110-1111
    • Krystal, J.H.1
  • 57
    • 77955909841 scopus 로고    scopus 로고
    • MTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists
    • Li, N., Lee, B., Liu, R. J., Banasr, M., Dwyer, J. M., Iwata, M., Li, X. Y., Aghajanian, G., and, Duman, R. S., (2010) mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists. Science 329, 959-964.
    • (2010) Science , vol.329 , pp. 959-964
    • Li, N.1    Lee, B.2    Liu, R.J.3    Banasr, M.4    Dwyer, J.M.5    Iwata, M.6    Li, X.Y.7    Aghajanian, G.8    Duman, R.S.9
  • 58
    • 33745168973 scopus 로고    scopus 로고
    • Muscarinic receptor subtypes in neuronal and non-neuronal cholinergic function
    • DOI 10.1111/j.1474-8673.2006.00368.x
    • Eglen, R. M., (2006) Muscarinic receptor subtypes in neuronal and non-neuronal cholinergic function. Auton. Autacoid Pharmacol. 26, 219-233. (Pubitemid 43898622)
    • (2006) Autonomic and Autacoid Pharmacology , vol.26 , Issue.3 , pp. 219-233
    • Eglen, R.M.1
  • 59
    • 77949930814 scopus 로고    scopus 로고
    • Impaired M(3) muscarinic acetylcholine receptor signal transduction through blockade of binding of multiple proteins to its third intracellular loop
    • Borroto-Escuela, D. O., Correia, P. A., Perez Alea, M., Narvaez, M., Garriga, P., Fuxe, K., and, Ciruela, F., (2010) Impaired M(3) muscarinic acetylcholine receptor signal transduction through blockade of binding of multiple proteins to its third intracellular loop. Cell. Physiol. Biochem. 25, 397-408.
    • (2010) Cell. Physiol. Biochem. , vol.25 , pp. 397-408
    • Borroto-Escuela, D.O.1    Correia, P.A.2    Perez Alea, M.3    Narvaez, M.4    Garriga, P.5    Fuxe, K.6    Ciruela, F.7
  • 61
    • 4644260473 scopus 로고    scopus 로고
    • GPCR interacting proteins (GIP)
    • DOI 10.1016/j.pharmthera.2004.06.004, PII S0163725804001007
    • Bockaert, J., Fagni, L., Dumuis, A., and, Marin, P., (2004) GPCR interacting proteins (GIP). Pharmacol. Ther. 103, 203-221. (Pubitemid 39298464)
    • (2004) Pharmacology and Therapeutics , vol.103 , Issue.3 , pp. 203-221
    • Bockaert, J.1    Fagni, L.2    Dumuis, A.3    Marin, P.4
  • 63
    • 0028270938 scopus 로고
    • Inhibition of G protein-coupled receptor signaling by expression of cytoplasmic domains of the receptor
    • Hawes, B. E., Luttrell, L. M., Exum, S. T., and, Lefkowitz, R. J., (1994) Inhibition of G protein-coupled receptor signaling by expression of cytoplasmic domains of the receptor. J. Biol. Chem. 269, 15776-15785. (Pubitemid 24202174)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.22 , pp. 15776-15785
    • Hawes, B.E.1    Luttrell, L.M.2    Exum, S.T.3    Lefkowitz, R.J.4
  • 64
    • 77953364015 scopus 로고    scopus 로고
    • The M(5) muscarinic acetylcholine receptor third intracellular loop regulates receptor function and oligomerization
    • Borroto-Escuela, D. O., Garcia-Negredo, G., Garriga, P., Fuxe, K., and, Ciruela, F., (2010) The M(5) muscarinic acetylcholine receptor third intracellular loop regulates receptor function and oligomerization. Biochim. Biophys. Acta 1803, 813-825.
    • (2010) Biochim. Biophys. Acta , vol.1803 , pp. 813-825
    • Borroto-Escuela, D.O.1    Garcia-Negredo, G.2    Garriga, P.3    Fuxe, K.4    Ciruela, F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.