The striatal neurotensin receptor modulates striatal and pallidal glutamate and GABA release: Functional evidence for a pallidal glutamate- GABA interaction via the pallidal-subthalamic nucleus loop

Journal of Neuroscience

Volumn 18, Issue 17, 1998, Pages 6977-6989

  Ferraro, Luca ^b   Antonelli, Tiziana ^b   O'Connor, William T ^b   Fuxe, Kjell ^b   Soubrié, Philippe ^b   Tanganelli, Sergio ^a  

^a UNIVERSITY OF FERRARA   (Italy)

^b NONE

Author keywords

Awake rat; Basal ganglia; Globus pallidus; Microdialysis; Neurotensin; SR48692; Striatum

Indexed keywords

2 [[1 (7 CHLORO 4 QUINOLINYL) 5 (2,6 DIMETHOXYPHENYL) 3 PYRAZOLYL]CARBONYLAMINO] 2 ADAMANTANECARBOXYLIC ACID; 4 AMINOBUTYRIC ACID; BICUCULLINE; GLUTAMIC ACID; NEUROTENSIN RECEPTOR;

4 AMINOBUTYRIC ACID RELEASE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; GLOBUS PALLIDUS; MALE; MICRODIALYSIS; NERVE PROJECTION; NEUROMODULATION; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0032171364     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.18-17-06977.1998     Document Type: Article

References (19)

1. 3H]N-propylnorapomorphine binding sites. Acta Physiol Scand 117:299-301.
2. Albin RL, Young AB, Penney JB (1989) The functional anatomy of basal ganglia disorders. Trends Neurosci 12:366-375.
3. Alexander GE, Crutcher M (1990) Functional architecture of basal ganglia circuits: neuronal substrates of parallel processing. Trends Neurosci 13:266-271.
4. Amalric M, Farin D, Dormont JF, Schmied A (1994) GABA-receptor activation in the globus pallidus and entopeduncolar nucleus: opposite effects on reaction time performance in the cat. Exp Brain Res 102:244-258.
5. 3H]SR 48692, in the guinea pig brain. J Pharmacol Exp Ther 273:1450-1458.
6. Blaha CD, Coury A, Fibiger HC, Phillips AG (1990) Effects of neurotensin on DA release and metabolism in the rat striatum and nucleus accumbens: cross-validation using in vivo voltammetry and microdialysis. Neuroscience 34:699-705.
7. Calò G, Sbrenna S, Blanchi C, Beani L (1997) Immediate and delayed effects of in vitro ischemia on glutamate efflux from guinea-pig cerebral cortex slices. Brain Res 751:300-306.
8. Carraway R, Leeman SE (1973) The isolation of a new hypotensive peptide, neurotensin, from bovine hypothalamus. J Biol Chem 248:6854-6861.
9. Castel MN, Morino P, Nylander I, Terenius L, HöKfelt T (1994) Differential dopaminergic regulation of the neurotensin striatonigral and striatopallidal pathways in the rat. Eur J Pharmacol 262:1-10.
10. Chevalier G, Deniau JM (1990) Disinhibition as a basic process in the expression of striatal functions. Trends Neurosci 13:277-280.
11. Da-Silva SL, Brandao ML, Tomaz C (1989) Behavioral effects of neurotensin applied to periventricular structures of rats. Braz J Med Biol Res 22:711-715.
12. Delfs JM, Anegawa NJ, Chesselet MF (1995) Glutamate decarboxylase messenger RNS in rat pallidum: comparison of the effects of haloperidol, clozapine, and combined haloperidol-scopolamine treatments. Neuroscience 66:67-80.
13. De Long MR (1990) Primate models of movement disorders of basal ganglia origin. Trends Neurosci 13:281-285.
14. Deutch AY, Zahm DS (1992) The current status of neurotensin-dopamine interactions: issues and speculations. Ann NY Acad Sci 668:232-252.
15. Drew KL, O'Connor WT, Kehr J, Ungerstedt U (1990) Regional specific effects of clozapine and haloperidol on GABA and dopamine release in rat basal ganglia. Eur J Pharmacol 187:385-397.
16. Fernandez A, Jenner P, Marsden CD, De Ceballos ML (1995) Characterization of neurotensin-like immunoreactivity in human basal ganglia: increased neurotensin levels in substantia nigra in Parkinson's disease. Peptides 16:339-346.
17. Ferraro L, Tanganelli S, O'Connor WT, Bianchi C, Ungerstedt U, Fuxe K (1995) Neurotensin increases endogenous glutamate release in the neostriatum of the awake rat. Synapse 20:362-364.
18. Ferraro L, O'Connor WT, Antonelli T, Fuxe K, Tanganelli S (1997) Differential effects of intrastriatal neurotensin(1-13) and neurotensin(8-13) on striatal dopamine and pallidal GABA release. A dualprobe microdialysis study in the awake rat. Eur J Neurosci 9:1838-1846.
19. Frey P, Fuxe K, Eneroth P, Agnati LF (1986) Effects of acute and long-term treatment with neuroleptics on regional telecenphalic neurotensin levels in the male rat. Neurochem Int 8:429-434.