메뉴 건너뛰기




Volumn 26, Issue 8, 2016, Pages 1008-1020

Age-related changes in Egr1 transcription and DNA methylation within the hippocampus

Author keywords

aging; epigenetic modulation; memory; transcriptional regulation

Indexed keywords

TRANSCRIPTION FACTOR EGR 1;

EID: 84978822613     PISSN: 10509631     EISSN: 10981063     Source Type: Journal    
DOI: 10.1002/hipo.22583     Document Type: Article
Times cited : (60)

References (86)
  • 1
    • 58249118862 scopus 로고    scopus 로고
    • Transcription factors in long-term memory and synaptic plasticity
    • Alberini CM. 2009. Transcription factors in long-term memory and synaptic plasticity. Physiol Rev 89:121–145.
    • (2009) Physiol Rev , vol.89 , pp. 121-145
    • Alberini, C.M.1
  • 3
    • 0029976891 scopus 로고    scopus 로고
    • Functional integrity of NMDA-dependent LTP induction mechanisms across the lifespan of F-344 rats
    • Barnes CA, Rao G, McNaughton BL. 1996. Functional integrity of NMDA-dependent LTP induction mechanisms across the lifespan of F-344 rats. Learn Mem 3:124–137.
    • (1996) Learn Mem , vol.3 , pp. 124-137
    • Barnes, C.A.1    Rao, G.2    McNaughton, B.L.3
  • 4
    • 0038206578 scopus 로고    scopus 로고
    • Gene microarrays in hippocampal aging: Statistical profiling identifies novel processes correlated with cognitive impairment
    • Blalock EM, Chen K-C, Sharrow K, Herman JP, Porter NM, Foster TC, Landfield PW. 2003. Gene microarrays in hippocampal aging: Statistical profiling identifies novel processes correlated with cognitive impairment. J Neurosci 23:3807–3819.
    • (2003) J Neurosci , vol.23 , pp. 3807-3819
    • Blalock, E.M.1    Chen, K.-C.2    Sharrow, K.3    Herman, J.P.4    Porter, N.M.5    Foster, T.C.6    Landfield, P.W.7
  • 5
    • 33750522659 scopus 로고    scopus 로고
    • Changes in transcription within the CA1 field of the hippocampus are associated with age-related spatial learning impairments
    • Burger C, López MC, Feller JA, Baker HV, Muzyczka N, Mandel RJ. 2007. Changes in transcription within the CA1 field of the hippocampus are associated with age-related spatial learning impairments. Neurobiol Learn Mem 87:21–41.
    • (2007) Neurobiol Learn Mem , vol.87 , pp. 21-41
    • Burger, C.1    López, M.C.2    Feller, J.A.3    Baker, H.V.4    Muzyczka, N.5    Mandel, R.J.6
  • 6
    • 41649089292 scopus 로고    scopus 로고
    • Genome-wide analysis of aging and learning-related genes in the hippocampal dentate gyrus
    • Burger C, Lopez MC, Baker HV, Mandel RJ, Muzyczka N. 2008. Genome-wide analysis of aging and learning-related genes in the hippocampal dentate gyrus. Neurobiol Learn Mem 89:379–396.
    • (2008) Neurobiol Learn Mem , vol.89 , pp. 379-396
    • Burger, C.1    Lopez, M.C.2    Baker, H.V.3    Mandel, R.J.4    Muzyczka, N.5
  • 7
    • 77649305060 scopus 로고    scopus 로고
    • Senescent synapses and hippocampal circuit dynamics
    • Burke SN, Barnes CA. 2010. Senescent synapses and hippocampal circuit dynamics. Trends Neurosci 33:153–161.
    • (2010) Trends Neurosci , vol.33 , pp. 153-161
    • Burke, S.N.1    Barnes, C.A.2
  • 8
    • 84863281305 scopus 로고    scopus 로고
    • Age-related memory impairment is associated with disrupted multivariate epigenetic coordination in the hippocampus
    • Castellano JF, Fletcher BR, Kelley-Bell B, Kim DH, Gallagher M, Rapp PR. 2012. Age-related memory impairment is associated with disrupted multivariate epigenetic coordination in the hippocampus. PloS One 7:e33249-
    • (2012) PloS One , vol.7
    • Castellano, J.F.1    Fletcher, B.R.2    Kelley-Bell, B.3    Kim, D.H.4    Gallagher, M.5    Rapp, P.R.6
  • 11
    • 0024403534 scopus 로고
    • Rapid increase of an immediate early gene messenger RNA in hippocampal neurons by synaptic NMDA receptor activation
    • Cole AJ, Saffen DW, Baraban JM, Worley PF. 1989. Rapid increase of an immediate early gene messenger RNA in hippocampal neurons by synaptic NMDA receptor activation. Nature 340:474–476.
    • (1989) Nature , vol.340 , pp. 474-476
    • Cole, A.J.1    Saffen, D.W.2    Baraban, J.M.3    Worley, P.F.4
  • 12
    • 79958038559 scopus 로고    scopus 로고
    • Epigenetic mechanisms in cognition
    • Day JJ, Sweatt JD. 2011. Epigenetic mechanisms in cognition. Neuron 70:813–829.
    • (2011) Neuron , vol.70 , pp. 813-829
    • Day, J.J.1    Sweatt, J.D.2
  • 15
    • 0037775776 scopus 로고    scopus 로고
    • Selectively reduced expression of synaptic plasticity-related genes in amyloid precursor protein + presenilin-1 transgenic mice
    • Dickey CA, Loring JF, Montgomery J, Gordon MN, Eastman PS, Morgan D. 2003. Selectively reduced expression of synaptic plasticity-related genes in amyloid precursor protein + presenilin-1 transgenic mice. J Neurosci 23:5219–5226.
    • (2003) J Neurosci , vol.23 , pp. 5219-5226
    • Dickey, C.A.1    Loring, J.F.2    Montgomery, J.3    Gordon, M.N.4    Eastman, P.S.5    Morgan, D.6
  • 16
    • 84908362166 scopus 로고    scopus 로고
    • A fine balance: Regulation of hippocampal Arc/Arg3.1 transcription, translation and degradation in a rat model of normal cognitive aging
    • Fletcher BR, Hill GS, Long JM, Gallagher M, Shapiro ML, Rapp PR. 2014. A fine balance: Regulation of hippocampal Arc/Arg3.1 transcription, translation and degradation in a rat model of normal cognitive aging. Neurobiol Learn Mem 115:58–67.
    • (2014) Neurobiol Learn Mem , vol.115 , pp. 58-67
    • Fletcher, B.R.1    Hill, G.S.2    Long, J.M.3    Gallagher, M.4    Shapiro, M.L.5    Rapp, P.R.6
  • 17
    • 0031451847 scopus 로고    scopus 로고
    • Age-associated changes in Ca(2+)-dependent processes: relation to hippocampal synaptic plasticity
    • Foster TC, Norris CM. 1997. Age-associated changes in Ca(2+)-dependent processes: relation to hippocampal synaptic plasticity. Hippocampus 7:602–612.
    • (1997) Hippocampus , vol.7 , pp. 602-612
    • Foster, T.C.1    Norris, C.M.2
  • 20
    • 0027214025 scopus 로고
    • Severity of spatial learning impairment in aging: Development of a learning index for performance in the Morris water maze
    • Gallagher M, Burwell R, Burchinal M. 1993. Severity of spatial learning impairment in aging: Development of a learning index for performance in the Morris water maze. Behav Neurosci 107:618–626.
    • (1993) Behav Neurosci , vol.107 , pp. 618-626
    • Gallagher, M.1    Burwell, R.2    Burchinal, M.3
  • 21
    • 0029991039 scopus 로고    scopus 로고
    • Circuit-specific alterations of N-methyl-D-aspartate receptor subunit 1 in the dentate gyrus of aged monkeys
    • Gazzaley AH, Siegel SJ, Kordower JH, Mufson EJ, Morrison JH. 1996. Circuit-specific alterations of N-methyl-D-aspartate receptor subunit 1 in the dentate gyrus of aged monkeys. Proc Natl Acad Sci U S A 93:3121–3125.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 3121-3125
    • Gazzaley, A.H.1    Siegel, S.J.2    Kordower, J.H.3    Mufson, E.J.4    Morrison, J.H.5
  • 23
    • 79957576736 scopus 로고    scopus 로고
    • Regulation of neural process growth, elaboration and structural plasticity by NF-κB
    • Gutierrez H, Davies AM. 2011. Regulation of neural process growth, elaboration and structural plasticity by NF-κB. Trends Neurosci 34:316–325.
    • (2011) Trends Neurosci , vol.34 , pp. 316-325
    • Gutierrez, H.1    Davies, A.M.2
  • 24
    • 0033490104 scopus 로고    scopus 로고
    • Environment-specific expression of the immediate-early gene Arc in hippocampal neuronal ensembles
    • Guzowski JF, McNaughton BL, Barnes CA, Worley PF. 1999. Environment-specific expression of the immediate-early gene Arc in hippocampal neuronal ensembles. Nat Neurosci 2:1120–1124.
    • (1999) Nat Neurosci , vol.2 , pp. 1120-1124
    • Guzowski, J.F.1    McNaughton, B.L.2    Barnes, C.A.3    Worley, P.F.4
  • 25
    • 0034213297 scopus 로고    scopus 로고
    • Inhibition of activity-dependent arc protein expression in the rat hippocampus impairs the maintenance of long-term potentiation and the consolidation of long-term memory
    • Guzowski JF, Lyford GL, Stevenson GD, Houston FP, McGaugh JL, Worley PF, Barnes CA. 2000. Inhibition of activity-dependent arc protein expression in the rat hippocampus impairs the maintenance of long-term potentiation and the consolidation of long-term memory. J Neurosci 20:3993–4001.
    • (2000) J Neurosci , vol.20 , pp. 3993-4001
    • Guzowski, J.F.1    Lyford, G.L.2    Stevenson, G.D.3    Houston, F.P.4    McGaugh, J.L.5    Worley, P.F.6    Barnes, C.A.7
  • 28
    • 84866114235 scopus 로고    scopus 로고
    • Characterization of CpG island DNA methylation of impairment-related genes in a rat model of cognitive aging
    • Haberman RP, Quigley CK, Gallagher M. 2012. Characterization of CpG island DNA methylation of impairment-related genes in a rat model of cognitive aging. Epigenetics 7:1008–1019.
    • (2012) Epigenetics , vol.7 , pp. 1008-1019
    • Haberman, R.P.1    Quigley, C.K.2    Gallagher, M.3
  • 29
    • 0035869488 scopus 로고    scopus 로고
    • Cellular imaging of zif268 expression in the hippocampus and amygdala during contextual and cued fear memory retrieval: selective activation of hippocampal CA1 neurons during the recall of contextual memories
    • Hall J, Thomas KL, Everitt BJ. 2001. Cellular imaging of zif268 expression in the hippocampus and amygdala during contextual and cued fear memory retrieval: selective activation of hippocampal CA1 neurons during the recall of contextual memories. J Neurosci 21:2186–2193.
    • (2001) J Neurosci , vol.21 , pp. 2186-2193
    • Hall, J.1    Thomas, K.L.2    Everitt, B.J.3
  • 31
    • 84874197869 scopus 로고    scopus 로고
    • Transcription of the immediate-early gene Arc in CA1 of the hippocampus reveals activity differences along the proximodistal axis that are attenuated by advanced age
    • Hartzell AL, Burke SN, Hoang LT, Lister JP, Rodriguez CN, Barnes CA. 2013. Transcription of the immediate-early gene Arc in CA1 of the hippocampus reveals activity differences along the proximodistal axis that are attenuated by advanced age. J Neurosci 33:3424–3433.
    • (2013) J Neurosci , vol.33 , pp. 3424-3433
    • Hartzell, A.L.1    Burke, S.N.2    Hoang, L.T.3    Lister, J.P.4    Rodriguez, C.N.5    Barnes, C.A.6
  • 36
    • 60849111389 scopus 로고    scopus 로고
    • Hippocampal and cognitive aging across the lifespan: A bioenergetic shift precedes and increased cholesterol trafficking parallels memory impairment
    • Kadish I, Thibault O, Blalock EM, Chen K-C, Gant JC, Porter NM, Landfield PW. 2009. Hippocampal and cognitive aging across the lifespan: A bioenergetic shift precedes and increased cholesterol trafficking parallels memory impairment. J Neurosci 29:1805–1816.
    • (2009) J Neurosci , vol.29 , pp. 1805-1816
    • Kadish, I.1    Thibault, O.2    Blalock, E.M.3    Chen, K.-C.4    Gant, J.C.5    Porter, N.M.6    Landfield, P.W.7
  • 37
    • 77249129746 scopus 로고    scopus 로고
    • Nuclear factor-κB is a critical mediator of stress-impaired neurogenesis and depressive behavior
    • Koo JW, Russo SJ, Ferguson D, Nestler EJ, Duman RS. 2010. Nuclear factor-κB is a critical mediator of stress-impaired neurogenesis and depressive behavior. Proc Natl Acad Sci U S A 107:2669–2674.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 2669-2674
    • Koo, J.W.1    Russo, S.J.2    Ferguson, D.3    Nestler, E.J.4    Duman, R.S.5
  • 43
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak KJ, Schmittgen TD. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25:402–408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 44
    • 54849426071 scopus 로고    scopus 로고
    • Epigenetic regulation of BDNF gene transcription in the consolidation of fear memory
    • Lubin FD, Roth TL, Sweatt JD. 2008. Epigenetic regulation of BDNF gene transcription in the consolidation of fear memory. J Neurosci 28:10576–10586.
    • (2008) J Neurosci , vol.28 , pp. 10576-10586
    • Lubin, F.D.1    Roth, T.L.2    Sweatt, J.D.3
  • 45
    • 84856428603 scopus 로고    scopus 로고
    • Increased pattern separation in the aged fascia dentata
    • Marrone DF, Adams AA, Satvat E. 2011. Increased pattern separation in the aged fascia dentata. Neurobiol Aging 32:2317.e23–2317.32.
    • (2011) Neurobiol Aging , vol.32 , pp. 2317.e23-2317.32
    • Marrone, D.F.1    Adams, A.A.2    Satvat, E.3
  • 48
    • 33847614418 scopus 로고    scopus 로고
    • Covalent modification of DNA regulates memory formation
    • Miller CA, Sweatt JD. 2007. Covalent modification of DNA regulates memory formation. Neuron 53:857–869.
    • (2007) Neuron , vol.53 , pp. 857-869
    • Miller, C.A.1    Sweatt, J.D.2
  • 51
    • 84930947913 scopus 로고    scopus 로고
    • Environmental enrichment reverses histone methylation changes in the aged hippocampus and restores age-related memory deficits
    • Morse SJ, Butler AA, Davis RL, Soller IJ, Lubin FD. 2015. Environmental enrichment reverses histone methylation changes in the aged hippocampus and restores age-related memory deficits. Biology 4:298–313.
    • (2015) Biology , vol.4 , pp. 298-313
    • Morse, S.J.1    Butler, A.A.2    Davis, R.L.3    Soller, I.J.4    Lubin, F.D.5
  • 52
    • 84864461542 scopus 로고    scopus 로고
    • Rescue of aging-associated decline in Dnmt3a2 expression restores cognitive abilities
    • Oliveira AMM, Hemstedt TJ, Bading H. 2012. Rescue of aging-associated decline in Dnmt3a2 expression restores cognitive abilities. Nat Neurosci 15:1111–1113.
    • (2012) Nat Neurosci , vol.15 , pp. 1111-1113
    • Oliveira, A.M.M.1    Hemstedt, T.J.2    Bading, H.3
  • 53
    • 27144530643 scopus 로고    scopus 로고
    • Vulnerability of dentate granule cells to disruption of Arc expression in human amyloid precursor protein transgenic mice
    • Palop JJ, Chin J, Bien-Ly N, Massaro C, Yeung BZ, Yu G-Q, Mucke L. 2005. Vulnerability of dentate granule cells to disruption of Arc expression in human amyloid precursor protein transgenic mice. J Neurosci 25:9686–9693.
    • (2005) J Neurosci , vol.25 , pp. 9686-9693
    • Palop, J.J.1    Chin, J.2    Bien-Ly, N.3    Massaro, C.4    Yeung, B.Z.5    Yu, G.-Q.6    Mucke, L.7
  • 54
    • 84868087624 scopus 로고    scopus 로고
    • Direct bisulfite sequencing for examination of DNA methylation with gene and nucleotide resolution from brain tissues
    • Unit 7.24-
    • Parrish RR, Day JJ, Lubin FD. 2012. Direct bisulfite sequencing for examination of DNA methylation with gene and nucleotide resolution from brain tissues. Curr Protoc Neurosci Chapter 7:Unit 7.24-
    • (2012) Curr Protoc Neurosci , vol.Chapter 7
    • Parrish, R.R.1    Day, J.J.2    Lubin, F.D.3
  • 60
    • 0037025059 scopus 로고    scopus 로고
    • Complexity of sensory environment drives the expression of candidate-plasticity gene, nerve growth factor induced-A
    • Pinaud R, Tremere LA, Penner MR, Hess FF, Robertson HA, Currie RW. 2002. Complexity of sensory environment drives the expression of candidate-plasticity gene, nerve growth factor induced-A. Neuroscience 112:573–582.
    • (2002) Neuroscience , vol.112 , pp. 573-582
    • Pinaud, R.1    Tremere, L.A.2    Penner, M.R.3    Hess, F.F.4    Robertson, H.A.5    Currie, R.W.6
  • 61
    • 38749147247 scopus 로고    scopus 로고
    • Qualitatively different hippocampal subfield engagement emerges with mastery of a spatial memory task by rats
    • Poirier GL, Amin E, Aggleton JP. 2008. Qualitatively different hippocampal subfield engagement emerges with mastery of a spatial memory task by rats. J Neurosci 28:1034–1045.
    • (2008) J Neurosci , vol.28 , pp. 1034-1045
    • Poirier, G.L.1    Amin, E.2    Aggleton, J.P.3
  • 62
    • 67650860446 scopus 로고    scopus 로고
    • Impaired long-term stability of CA1 place cell representation in mice lacking the transcription factor zif268/egr1
    • Renaudineau S, Poucet B, Laroche S, Davis S, Save E. 2009. Impaired long-term stability of CA1 place cell representation in mice lacking the transcription factor zif268/egr1. Proc Natl Acad Sci U S A 106:11771–11775.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 11771-11775
    • Renaudineau, S.1    Poucet, B.2    Laroche, S.3    Davis, S.4    Save, E.5
  • 63
    • 0037936789 scopus 로고    scopus 로고
    • Impact of aging on hippocampal function: plasticity, network dynamics, and cognition
    • Rosenzweig ES, Barnes CA. 2003. Impact of aging on hippocampal function: plasticity, network dynamics, and cognition. Prog Neurobiol 69:143–179.
    • (2003) Prog Neurobiol , vol.69 , pp. 143-179
    • Rosenzweig, E.S.1    Barnes, C.A.2
  • 65
    • 63449085750 scopus 로고    scopus 로고
    • Lasting epigenetic influence of early-life adversity on the BDNF gene
    • Roth TL, Lubin FD, Funk AJ, Sweatt JD. 2009. Lasting epigenetic influence of early-life adversity on the BDNF gene. Biol Psychiatry 65:760–769.
    • (2009) Biol Psychiatry , vol.65 , pp. 760-769
    • Roth, T.L.1    Lubin, F.D.2    Funk, A.J.3    Sweatt, J.D.4
  • 66
    • 79958765149 scopus 로고    scopus 로고
    • Epigenetic modification of hippocampal Bdnf DNA in adult rats in an animal model of post-traumatic stress disorder
    • Roth TL, Zoladz PR, Sweatt JD, Diamond DM. 2011. Epigenetic modification of hippocampal Bdnf DNA in adult rats in an animal model of post-traumatic stress disorder. J Psychiatr Res 45:919–926.
    • (2011) J Psychiatr Res , vol.45 , pp. 919-926
    • Roth, T.L.1    Zoladz, P.R.2    Sweatt, J.D.3    Diamond, D.M.4
  • 67
    • 33947534891 scopus 로고    scopus 로고
    • Hippocampal expression analyses reveal selective association of immediate-early, neuroenergetic, and myelinogenic pathways with cognitive impairment in aged rats
    • Rowe WB, Blalock EM, Chen K-C, Kadish I, Wang D, Barrett JE, Thibault O, Porter NM, Rose GM, Landfield PW. 2007. Hippocampal expression analyses reveal selective association of immediate-early, neuroenergetic, and myelinogenic pathways with cognitive impairment in aged rats. J Neurosci 27:3098–3110.
    • (2007) J Neurosci , vol.27 , pp. 3098-3110
    • Rowe, W.B.1    Blalock, E.M.2    Chen, K.-C.3    Kadish, I.4    Wang, D.5    Barrett, J.E.6    Thibault, O.7    Porter, N.M.8    Rose, G.M.9    Landfield, P.W.10
  • 70
    • 0036194064 scopus 로고    scopus 로고
    • Imaging hippocampal function across the human life span: is memory decline normal or not?
    • Small SA, Tsai WY, DeLaPaz R, Mayeux R, Stern Y. 2002. Imaging hippocampal function across the human life span: is memory decline normal or not? Ann Neurol 51:290–295.
    • (2002) Ann Neurol , vol.51 , pp. 290-295
    • Small, S.A.1    Tsai, W.Y.2    DeLaPaz, R.3    Mayeux, R.4    Stern, Y.5
  • 71
    • 2342557824 scopus 로고    scopus 로고
    • Imaging correlates of brain function in monkeys and rats isolates a hippocampal subregion differentially vulnerable to aging
    • Small SA, Chawla MK, Buonocore M, Rapp PR, Barnes CA. 2004. Imaging correlates of brain function in monkeys and rats isolates a hippocampal subregion differentially vulnerable to aging. Proc Natl Acad Sci U S A 101:7181–7186.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 7181-7186
    • Small, S.A.1    Chawla, M.K.2    Buonocore, M.3    Rapp, P.R.4    Barnes, C.A.5
  • 72
    • 0035036344 scopus 로고    scopus 로고
    • Selective targeting of newly synthesized Arc mRNA to active synapses requires NMDA receptor activation
    • Steward O, Worley PF. 2001. Selective targeting of newly synthesized Arc mRNA to active synapses requires NMDA receptor activation. Neuron 30:227–240.
    • (2001) Neuron , vol.30 , pp. 227-240
    • Steward, O.1    Worley, P.F.2
  • 73
    • 34548822478 scopus 로고    scopus 로고
    • Effects of aging, dietary restriction and glucocorticoid treatment on housekeeping gene expression in rat cortex and hippocampus-evaluation by real time RT-PCR
    • Tanic N, Perovic M, Mladenovic A, Ruzdijic S, Kanazir S. 2007. Effects of aging, dietary restriction and glucocorticoid treatment on housekeeping gene expression in rat cortex and hippocampus-evaluation by real time RT-PCR. J Mol Neurosci 32:38–46.
    • (2007) J Mol Neurosci , vol.32 , pp. 38-46
    • Tanic, N.1    Perovic, M.2    Mladenovic, A.3    Ruzdijic, S.4    Kanazir, S.5
  • 74
    • 77549086301 scopus 로고    scopus 로고
    • Calcium and normal brain ageing
    • Toescu EC, Vreugdenhil M. 2010. Calcium and normal brain ageing. Cell Calcium 47:158–164.
    • (2010) Cell Calcium , vol.47 , pp. 158-164
    • Toescu, E.C.1    Vreugdenhil, M.2
  • 75
    • 4544262624 scopus 로고    scopus 로고
    • Ca2+ regulation and gene expression in normal brain aging
    • Toescu EC, Verkhratsky A, Landfield PW. 2004. Ca2+ regulation and gene expression in normal brain aging. Trends Neurosci 27:614–620.
    • (2004) Trends Neurosci , vol.27 , pp. 614-620
    • Toescu, E.C.1    Verkhratsky, A.2    Landfield, P.W.3
  • 76
    • 3242802723 scopus 로고    scopus 로고
    • Differences in hippocampal neuronal population responses to modifications of an environmental context: Evidence for distinct, yet complementary, functions of CA3 and CA1 ensembles
    • Vazdarjanova A, Guzowski JF. 2004. Differences in hippocampal neuronal population responses to modifications of an environmental context: Evidence for distinct, yet complementary, functions of CA3 and CA1 ensembles. J Neurosci 24:6489–6496.
    • (2004) J Neurosci , vol.24 , pp. 6489-6496
    • Vazdarjanova, A.1    Guzowski, J.F.2
  • 77
    • 0036896810 scopus 로고    scopus 로고
    • Experience-dependent coincident expression of the effector immediate-early genes arc and Homer 1a in hippocampal and neocortical neuronal networks
    • Vazdarjanova A, McNaughton BL, Barnes CA, Worley PF, Guzowski JF. 2002. Experience-dependent coincident expression of the effector immediate-early genes arc and Homer 1a in hippocampal and neocortical neuronal networks. J Neurosci 22:10067–10071.
    • (2002) J Neurosci , vol.22 , pp. 10067-10071
    • Vazdarjanova, A.1    McNaughton, B.L.2    Barnes, C.A.3    Worley, P.F.4    Guzowski, J.F.5
  • 78
    • 2542637241 scopus 로고    scopus 로고
    • Altered hippocampal transcript profile accompanies an age-related spatial memory deficit in mice
    • Verbitsky M, Yonan AL, Malleret G, Kandel ER, Gilliam TC, Pavlidis P. 2004. Altered hippocampal transcript profile accompanies an age-related spatial memory deficit in mice. Learn Mem 11:253–260.
    • (2004) Learn Mem , vol.11 , pp. 253-260
    • Verbitsky, M.1    Yonan, A.L.2    Malleret, G.3    Kandel, E.R.4    Gilliam, T.C.5    Pavlidis, P.6
  • 80
    • 33847093463 scopus 로고    scopus 로고
    • The transcription factor nerve growth factor-inducible protein A mediates epigenetic programming: altering epigenetic marks by immediate-early genes
    • Weaver ICG, D'Alessio AC, Brown SE, Hellstrom IC, Dymov S, Sharma S, Szyf M, Meaney MJ. 2007. The transcription factor nerve growth factor-inducible protein A mediates epigenetic programming: altering epigenetic marks by immediate-early genes. J Neurosci 27:1756–1768.
    • (2007) J Neurosci , vol.27 , pp. 1756-1768
    • Weaver, I.C.G.1    D'Alessio, A.C.2    Brown, S.E.3    Hellstrom, I.C.4    Dymov, S.5    Sharma, S.6    Szyf, M.7    Meaney, M.J.8
  • 81
    • 0027164617 scopus 로고
    • Regionally specific loss of neurons in the aging human hippocampus
    • West MJ. 1993. Regionally specific loss of neurons in the aging human hippocampus. Neurobiol Aging 14:287–293.
    • (1993) Neurobiol Aging , vol.14 , pp. 287-293
    • West, M.J.1
  • 82
    • 33749375248 scopus 로고    scopus 로고
    • Tumor necrosis factor α triggers proliferation of adult neural stem cells via IKK/NF-κB signaling
    • Widera D, Mikenberg I, Elvers M, Kaltschmidt C, Kaltschmidt B. 2006. Tumor necrosis factor α triggers proliferation of adult neural stem cells via IKK/NF-κB signaling. BMC Neurosci 7:64-
    • (2006) BMC Neurosci , vol.7 , pp. 64
    • Widera, D.1    Mikenberg, I.2    Elvers, M.3    Kaltschmidt, C.4    Kaltschmidt, B.5
  • 83
    • 80053125086 scopus 로고    scopus 로고
    • Pattern separation in the hippocampus
    • Yassa MA, Stark CEL. 2011. Pattern separation in the hippocampus. Trends Neurosci 34:515–525.
    • (2011) Trends Neurosci , vol.34 , pp. 515-525
    • Yassa, M.A.1    Stark, C.E.L.2
  • 84
    • 80051937468 scopus 로고    scopus 로고
    • Pattern separation deficits associated with increased hippocampal CA3 and dentate gyrus activity in nondemented older adults
    • Yassa MA, Lacy JW, Stark SM, Albert MS, Gallagher M, Stark CEL. 2011a. Pattern separation deficits associated with increased hippocampal CA3 and dentate gyrus activity in nondemented older adults. Hippocampus 21:968–979.
    • (2011) Hippocampus , vol.21 , pp. 968-979
    • Yassa, M.A.1    Lacy, J.W.2    Stark, S.M.3    Albert, M.S.4    Gallagher, M.5    Stark, C.E.L.6
  • 85
    • 79957738688 scopus 로고    scopus 로고
    • Age-related memory deficits linked to circuit-specific disruptions in the hippocampus
    • Yassa MA, Mattfeld AT, Stark SM, Stark CEL. 2011b. Age-related memory deficits linked to circuit-specific disruptions in the hippocampus. Proc Natl Acad Sci U S A 108:8873–8878.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 8873-8878
    • Yassa, M.A.1    Mattfeld, A.T.2    Stark, S.M.3    Stark, C.E.L.4
  • 86


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.