Calcium and normal brain ageing

Cell Calcium

Volumn 47, Issue 2, 2010, Pages 158-164

  Toescu, Emil C ^a   Vreugdenhil, Martin ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Ageing; BAPTA; Brain activity; Ca buffers; Calcium; EGTA; Endoplasmic reticulum; Frequency facilitation; Gamma oscillations; Hippocampus; Interneurons; Long term potentiation (LTP); LTD; Mitochondria; Neurodegeneration; Neuron; Neuronal networks; Normal brain ageing; Plasma membrane Ca ATPase (PMCA); Ryanodine; Slow afterhyperpolarization; VDCC; Voltage operated calcium channels (VOCCs)

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); N METHYL DEXTRO ASPARTIC ACID RECEPTOR; RYANODINE RECEPTOR; VOLTAGE GATED CALCIUM CHANNEL;

AGING; ALZHEIMER DISEASE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CALCIUM SIGNALING; CALCIUM TRANSPORT; COGNITIVE DEFECT; HUMAN; LEARNING; NERVE CELL NECROSIS; NERVE CELL NETWORK; NERVE CELL PLASTICITY; NERVE EXCITABILITY; NONHUMAN; PRIORITY JOURNAL; REVIEW;

EID: 77549086301     PISSN: 01434160     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ceca.2009.11.013     Document Type: Review

References (77)

1. Khachaturian Z.S. Towards theories of brain aging. In: Kay D., and Burrows G. (Eds). Handbook of Studies on Psychiatry and Old Age (1984), Elsevier, Amsterdam 7-30
2. Khachaturian Z.S. Calcium hypothesis of Alzheimer's disease and brain aging. Ann. N. Y. Acad. Sci. 747 (1994) 1-11
3. Case R.M., Eisner D., Gurney A., Jones O., Muallem S., and Verkhratsky A. Evolution of calcium homeostasis: from birth of the first cell to an omnipresent signalling system. Cell Calcium 42 (2007) 345-350
4. Berridge M.J., Bootman M.D., and Lipp P. Calcium-a life and death signal. Nature 395 (1998) 645-648
5. Choi D.W., Maulucci-Gedde M., and Kriegstein A.R. Glutamate neurotoxicity in cortical cell culture. J. Neurosci. 7 (1987) 357-368
6. Hof P.R., and Morrison J.H. The aging brain: morphomolecular senescence of cortical circuits. Trends Neurosci. 27 (2004) 607-613
7. Sterio D.C. The unbiased estimation of number and sizes of arbitrary particles using the disector. J. Microsc. 134 Pt 2 (1984) 127-136
8. Morrison J., and Hof P. Life and death of neurons in the aging brain. Science 278 (1997) 412-419
9. Toescu E.C., and Verkhratsky A. The importance of being subtle: small changes in calcium homeostasis control cognitive decline in normal aging. Aging Cell 6 (2007) 267-273
10. LaFerla F.M. Calcium dyshomeostasis and intracellular signalling in Alzheimer disease. Nat. Rev. Neurosci. 3 (2002) 862-872
11. Bezprozvanny I. Calcium signaling and neurodegenerative diseases. Trends Mol. Med. 15 (2009) 89-100
12. 2+-dependent afterhyperpolarizations in hippocampal neurones of aged rats. Science 226 (1984) 1089-1092
13. Thibault O., and Landfield P.W. Increase in single L-type calcium channels in hippocampal neurons during aging. Science 272 (1996) 1017-1020
14. Michaelis M., Bigelow D., Sconeich C., Williams T., Ramonada L., Yin D., Huhmer A., Yao Y., Gao J., and Squier T. Decreased plasma membrane calcium transport activity in aging brain. Life Sci. 59 (1996) 405-412
15. 2+ sink' in cerebellar granule neurones. Neuroreport 9 (1998) 1227-12231
16. Solovyova N., Veselovsky N., Toescu E.C., and Verkhratsky A. Ca(2+) dynamics in the lumen of the endoplasmic reticulum in sensory neurons: direct visualization of Ca(2+)-induced Ca(2+) release triggered by physiological Ca(2+) entry. EMBO J. 21 (2002) 622-630
17. 2+ signaling. J. Cell. Mol. Med. 4 (2000) 164-175
18. Nicholls D.G. Mitochondrial membrane potential and aging. Aging Cell 3 (2004) 35-40
19. Mattson M.P., Gleichmann M., and Cheng A. Mitochondria in neuroplasticity and neurological disorders. Neuron 60 (2008) 748-766
20. 2+ signaling. Physiology (Bethesda) 23 (2008) 84-94
21. Thibault O., Gant J.C., and Landfield P.W. Expansion of the calcium hypothesis of brain aging and Alzheimer's disease: minding the store. Aging Cell 6 (2007) 307-317
22. 2+ release. J. Neurosci. 26 (2006) 3482-3490
23. Toescu E.C. Normal brain ageing: models and mechanisms. Philos. Trans. R. Soc. Lond. 360 (2005) 2347-2354
24. Tonkikh A., Janus C., El-Beheiry H., Pennefather P.S., Samoilova M., McDonald P., Ouanounou A., and Carlen P.L. Calcium chelation improves spatial learning and synaptic plasticity in aged rats. Exp. Neurol. 197 (2006) 291-300
25. Tonkikh A.A., and Carlen P.L. Impaired presynaptic cytosolic and mitochondrial calcium dynamics in aged compared to young adult hippocampal CA1 synapses ameliorated by calcium chelation. Neuroscience 159 (2009) 1300-1308
26. Ouanounou A., Zhang L., Charlton M.P., and Carlen P.L. Differential modulation of synaptic transmission by calcium chelators in young and aged hippocampal CA1 neurons: evidence for altered calcium homeostasis in aging. J. Neurosci. 19 (1999) 906-915
27. Murchison D., and Griffith W.H. Calcium buffering systems and calcium signaling in aged rat basal forebrain neurons. Aging Cell 6 (2007) 297-305
28. Murchison D., McDermott A.N., Lasarge C.L., Peebles K.A., Bizon J.L., and Griffith W.H. Enhanced calcium buffering in f344 rat cholinergic Basal forebrain neurons is associated with age-related cognitive impairment. J. Neurophysiol. 102 (2009) 2194-2207
29. Verkhratsky A., and Toescu E. Calcium and neuronal ageing. Trends Neurosci. 21 (1998) 2-7
30. 2+ homeostasis in aged cerebellar granule neurones in brain slices. J. Neurosci. 22 (2002) 10761-10771
31. 2+]i and L-type calcium channel activity in aged hippocampal neurons: relationship to impaired synaptic plasticity. J. Neurosci. 21 (2001) 9744-9756
32. Brewer G.J., Reichensperger J.D., and Brinton R.D. Prevention of age-related dysregulation of calcium dynamics by estrogen in neurons. Neurobiol. Aging 27 (2006) 306-317
33. Raza M., Deshpande L.S., Blair R.E., Carter D.S., Sombati S., and DeLorenzo R.J. Aging is associated with elevated intracellular calcium levels and altered calcium homeostatic mechanisms in hippocampal neurons. Neurosci. Lett. 418 (2007) 77-81
34. Hajieva P., Kuhlmann C., Luhmann H.J., and Behl C. Impaired calcium homeostasis in aged hippocampal neurons. Neurosci. Lett. 451 (2009) 119-123
35. 2+ homeostatic mechanisms in hippocampal neurons surviving brain injury. Eur. J. Neurosci. 27 (2008) 1659-1672
36. 2+ pump activity in rat hippocampal neurons. J. Neurochem. 98 (2006) 1646-1656
37. Brewer L.D., Thibault O., Staton J., Thibault V., Rogers J.T., Garcia-Ramos G., Kraner S., Landfield P.W., and Porter N.M. Increased vulnerability of hippocampal neurons with age in culture: temporal association with increases in NMDA receptor current, NR2A subunit expression and recruitment of L-type calcium channels. Brain Res. 1151 (2007) 20-31
38. Wong T.P., Marchese G., Casu M.A., Ribeiro-da-Silva A., Cuello A.C., and De Koninck Y. Loss of presynaptic and postsynaptic structures is accompanied by compensatory increase in action potential-dependent synaptic input to layer V neocortical pyramidal neurons in aged rats. J. Neurosci. 20 (2000) 8596-8606
39. Disterhoft J.F., and Oh M.M. Learning, aging and intrinsic neuronal plasticity. Trends Neurosci. 29 (2006) 587-599
40. Brown D.A., Lancaster B., and Shah M.M. Hippocalcin: a new solution to an old puzzle. Neuron 53 (2007) 467-468
41. Tzingounis A.V., Kobayashi M., Takamatsu K., and Nicoll R.A. Hippocalcin gates the calcium activation of the slow afterhyperpolarization in hippocampal pyramidal cells. Neuron 53 (2007) 487-493
42. Campbell L.W., Hao S.-Y., Thibault O., Blalock E.M., and LAndfield P.W. Aging changes in voltage-gated calcium currents in hippocampal CA1 neurones. J. Neurosci. 16 (1996) 6286-6295
43. Verkhratsky A. Physiology and pathophysiology of the calcium store in the endoplasmic reticulum of neurons. Physiol. Rev. 85 (2005) 201-279
44. Toescu E.C., and Verkhratsky A. Neuronal ageing from an intraneuronal perspective: roles of endoplasmic reticulum and mitochondria. Cell Calcium 34 (2003) 311-323
45. Tombaugh G.C., Rowe W.B., and Rose G.M. The slow afterhyperpolarization in hippocampal CA1 neurons covaries with spatial learning ability in aged Fisher 344 rats. J. Neurosci. 25 (2005) 2609-2616
46. Matthews E.A., Linardakis J.M., and Disterhoft J.F. The fast and slow afterhyperpolarizations are differentially modulated in hippocampal neurons by aging and learning. J. Neurosci. 29 (2009) 4750-4755
47. Clapham D.E. Calcium signaling. Cell 131 (2007) 1047-1058
48. Disterhoft J.F., and Oh M.M. Alterations in intrinsic neuronal excitability during normal aging. Aging Cell 6 (2007) 327-336
49. C.B. Lu, J.B. Hamilton, A.D. Powell, E.C. Toescu, M. Vreugdenhil, Effect of ageing on CA3 interneuron sAHP and gamma oscillations is activity-dependent, Neurobiol. Aging, doi:10.1016/j.neurobiolaging.2009.05.006, in press.
50. Kudryashova I.V. Frequency facilitation in the hippocampal slices of conditioned rats. Neuroscience 75 (1996) 695-702
51. Hebb D. The Organization of Behavior (1949), Wiley, New York
52. Morgan S.L., and Teyler T.J. VDCCs and NMDARs underlie two forms of LTP in CA1 hippocampus in vivo. J. Neurophysiol. 82 (1999) 736-740
53. Rosenzweig E.S., and Barnes C.A. Impact of aging on hippocampal function: plasticity, network dynamics, and cognition. Prog. Neurobiol. 69 (2003) 143-179
54. Ris L., and Godaux E. Synapse specificity of long-term potentiation breaks down with aging. Learn. Mem. 14 (2007) 185-189
55. Foster T.C. Calcium homeostasis and modulation of synaptic plasticity in the aged brain. Aging Cell 6 (2007) 319-325
56. Dan Y., and Poo M.M. Spike timing-dependent plasticity: from synapse to perception. Physiol. Rev. 86 (2006) 1033-1048
57. Csicsvari J., Jamieson B., Wise K.D., and Buzsaki G. Mechanisms of gamma oscillations in the hippocampus of the behaving rat. Neuron 37 (2003) 311-322
58. Womelsdorf T., and Fries P. The role of neuronal synchronization in selective attention. Curr. Opin. Neurobiol. 17 (2007) 154-160
59. Tallon-Baudry C. The roles of gamma-band oscillatory synchrony in human visual cognition. Front. Biosci. 14 (2009) 321-332
60. Bottger D., Herrmann C.S., and von Cramon D.Y. Amplitude differences of evoked alpha and gamma oscillations in two different age groups. Int. J. Psychophysiol. 45 (2002) 245-251
61. Werkle-Bergner M., Shing Y.L., Muller V., Li S.C., and Lindenberger U. EEG gamma-band synchronization in visual coding from childhood to old age: evidence from evoked power and inter-trial phase locking. Clin. Neurophysiol. 120 (2009) 1291-1302
62. Lenz D., Schadow J., Thaerig S., Busch N.A., and Herrmann C.S. What's that sound? Matches with auditory long-term memory induce gamma activity in human EEG. Int. J. Psychophysiol. 64 (2007) 31-38
63. Jeschke M., Lenz D., Budinger E., Herrmann C.S., and Ohl F.W. Gamma oscillations in gerbil auditory cortex during a target-discrimination task reflect matches with short-term memory. Brain Res. 1220 (2008) 70-80
64. Fuchs E.C., Zivkovic A.R., Cunningham M.O., Middleton S., Lebeau F.E., Bannerman D.M., Rozov A., Whittington M.A., Traub R.D., Rawlins J.N., and Monyer H. Recruitment of parvalbumin-positive interneurons determines hippocampal function and associated behavior. Neuron 53 (2007) 591-604
65. Buhl E.H., Tamas G., and Fisahn A. Cholinergic activation and tonic excitation induce persistent gamma oscillations in mouse somatosensory cortex in vitro. J. Physiol. 513 Pt 1 (1998) 117-126
66. Fisahn A., Pike F.G., Buhl E.H., and Paulsen O. Cholinergic induction of network oscillations at 40 Hz in the hippocampus in vitro. Nature 394 (1998) 186-189
67. Pietersen A.N., Patel N., Jefferys J.G., and Vreugdenhil M. Comparison between spontaneous and kainate-induced gamma oscillations in the mouse hippocampus in vitro. Eur. J. Neurosci. 29 (2009) 2145-2156
68. Fisahn A. Kainate receptors and rhythmic activity in neuronal networks: hippocampal gamma oscillations as a tool. J. Physiol. 562 (2005) 65-72
69. Fries P., Nikolic D., and Singer W. The gamma cycle. Trends Neurosci. 30 (2007) 309-316
70. Vreugdenhil M., and Toescu E.C. Age-dependent reduction of gamma oscillations in the mouse hippocampus in vitro. Neuroscience 132 (2005) 1151-1157
71. Driver J.E., Racca C., Cunningham M.O., Towers S.K., Davies C.H., Whittington M.A., and LeBeau F.E. Impairment of hippocampal gamma-frequency oscillations in vitro in mice overexpressing human amyloid precursor protein (APP). Eur. J. Neurosci. 26 (2007) 1280-1288
72. 2 and concomitant changes in mitochondrial redox state. J. Neurosci. 28 (2008) 1153-1162
73. Hajos N., Palhalmi J., Mann E.O., Nemeth B., Paulsen O., and Freund T.F. Spike timing of distinct types of GABAergic interneuron during hippocampal gamma oscillations in vitro. J. Neurosci. 24 (2004) 9127-9137
74. Turner J.G., Hughes L.F., and Caspary D.M. Affects of aging on receptive fields in rat primary auditory cortex layer V neurons. J. Neurophysiol. 94 (2005) 2738-2747
75. Yang Y., Liang Z., Li G., Wang Y., and Zhou Y. Aging affects response variability of V1 and MT neurons in rhesus monkeys. Brain Res. 1274 (2009) 21-27
76. Wilson I.A., Ikonen S., Gallagher M., Eichenbaum H., and Tanila H. Age-associated alterations of hippocampal place cells are subregion specific. J. Neurosci. 25 (2005) 6877-6886
77. Yan J., Zhang Y., Roder J., and McDonald R.J. Aging effects on spatial tuning of hippocampal place cells in mice. Exp. Brain Res. 150 (2003) 184-193